We have located links that may give you full text access.
JOURNAL ARTICLE
REVIEW
Assessing the aquatic toxicity of complex hydrocarbon mixtures using solid phase microextraction.
Toxicology Letters 2000 March 16
Assessing the ecotoxicity of hydrocarbon mixtures is complicated by the complex nature of these mixtures. Traditional analytical methods for characterizing hydrocarbon contamination are not good predictors of potential ecotoxicity because these methods fail to characterize the bioavailability of individual hydrocarbon components. Recent research indicates that hydrocarbons act by a common narcotic mode of action and that ecotoxicity occurs when the molar concentration in organism lipid exceeds a critical threshold. Since the ecotoxicity of narcotic mixtures appears to be additive, ecotoxicity thus depends upon the partitioning of individual hydrocarbons from the environment to lipids and the total molar sum of individual hydrocarbons in lipids. These insights have led previous investigators to advance the concept of 'biomimetic' extraction as a novel analytical tool for assessing narcosis-type or 'baseline'. Drawing from this earlier work, a simple method to quantify bioavailable petroleum hydrocarbons (BPHs) in hydrocarbon-contaminated aqueous and soil/sediment samples was developed. The proposed method combines the essential features of biomimetic extraction for simulating the bioconcentration process with the analytical advantages of solid phase microextraction (SPME). The procedure for determining BPH involves two steps. The sample is first equilibrated with a SPME fiber that serves as a surrogate for organism lipids. The total moles of hydrocarbons that partition to the SPME fiber is then quantified using GC/FID. The capability of this method to predict ecotoxicity was assessed by comparing BPH measurements for hydrocarbon contaminated aqueous samples to corresponding toxicity test results for rainbow trout. Results indicate that BPH analyses correlate to the observed acute toxicity. Consequently, BPH analyses offer a promising, cost-effective screening tool for predicting aquatic toxicity of complex hydrocarbon mixtures.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app