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Collection analysis matrix quality assurance

Rafat Mohebifar, Hana Hasani, Ameneh Barikani, Sima Rafiei
OBJECTIVES: Providing high service quality is one of the main functions of health systems. Measuring service quality is the basic prerequisite for improving quality. The aim of this study was to evaluate the quality of service in teaching hospitals using importance-performance analysis matrix. METHODS: A descriptive-analytic study was conducted through a cross-sectional method in six academic hospitals of Qazvin, Iran, in 2012. A total of 360 patients contributed to the study...
August 2016: Osong Public Health and Research Perspectives
Susan Waldron, E Marian Scott, Leena E Vihermaa, Jason Newton
RATIONALE: We describe an analytical procedure that allows sample collection and measurement of carbon isotopic composition (δ(13)C(V-PDB) value) and dissolved inorganic carbon concentration, [DIC], in aqueous samples without further manipulation post field collection. By comparing outputs from two different mass spectrometers, we quantify with the statistical rigour uncertainty associated with the estimation of an unknown measurement. This is rarely undertaken, but it is needed to understand the significance of field data and to interpret quality assurance exercises...
May 30, 2014: Rapid Communications in Mass Spectrometry: RCM
Pim Mw Janssens
BACKGROUND: Prospective risk analysis (PRA) is an essential element in quality assurance for clinical laboratories. Practical approaches to conducting PRA in laboratories, however, are scarce. METHODS: On the basis of the classical Failure Mode and Effect Analysis method, an approach to PRA was developed for application to key laboratory processes. First, the separate, major steps of the process under investigation are identified. Scores are then given for the Probability (P) and Consequence (C) of predefined types of failures and the chances of Detecting (D) these failures...
November 2014: Annals of Clinical Biochemistry
Sotirios Stathakis, Pamela Myers, Carlos Esquivel, Panayiotis Mavroidis, Nikos Papanikolaou
PURPOSE: In this study, the authors are evaluating a new, commercially available 2D array that offers 3D dose reconstruction for patient specific intensity modulated radiation therapy quality assurance (IMRT QA). METHODS: The OCTAVIUS 4D system and its accompanying software (VERISOFT) by PTW were evaluated for the accuracy of the dose reconstruction for patient specific pretreatment IMRT QA. OCTAVIUS 4D measures the dose plane at the linac isocenter as the phantom rotates synchronously with the gantry, maintaining perpendicularity with the beam, by means of an inclinometer and a motor...
July 2013: Medical Physics
Víctor Reyes-Alcázar, Marta Casas-Delgado, Manuel Herrera-Usagre, Antonio Torres-Olivera
The aim of this study was to identify the different groups that can affect or be affected by an agency charged with the promoting and guaranteeing of health care quality in Andalusian region (Spain) and to provide a framework with the stakeholders included in different categories. The study adopted a cross-sectional research design. A case study with structured interviews among Andalusian Agency for Healthcare Quality Steering Committee members was carried out in 2010 to define stakeholders' categories and map the interest groups using 5 attributes: influence, importance, legitimacy, power, and urgency...
October 2012: Health Care Manager
Alysa Fairchild, Edwin Aird, Paul A Fenton, Vincent Gregoire, Akos Gulyban, Denis Lacombe, Oscar Matzinger, Philip Poortmans, Pascal Ruyskart, Damien C Weber, Coen W Hurkmans
OBJECTIVE: Quality assurance (QA) in clinical trials is essential to ensure treatment is safely and effectively delivered. As QA requirements have increased in complexity in parallel with evolution of radiation therapy (RT) delivery, a need to facilitate digital data exchange emerged. Our objective is to present the platform developed for the integration and standardization of QART activities across all EORTC trials involving RT. METHODS: The following essential requirements were identified: secure and easy access without on-site software installation; integration within the existing EORTC clinical remote data capture system; and the ability to both customize the platform to specific studies and adapt to future needs...
June 2012: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Sylwia Król, Bożena Zabiegała, Jacek Namieśnik
The paper reviews the subject literature concerning analytical procedures routinely sed for monitoring polybrominated diphenyl ethers (PBDE) in environmental samples. It describes and summarizes subsequent stages of analytical procedure including sample collection and preparation, extraction, clean-up and final determination. Different approaches with their advantages and limitations are presented. Special attention is drawn to the newly developed, promising extraction techniques, especially: liquid-liquid-microextraction (LLME) with its modifications, cloud point extraction (CPE) and hollow fiber microextraction...
May 15, 2012: Talanta
Pradip Kumar Ray, V K Tewari
Management of Tata Steel, the largest steel making company of India in the private sector, felt the need to develop a framework to determine the levels of ergonomic performance at its different workplaces. The objectives of the study are manifold: to identify and characterize the ergonomic variables for a given worksystem with regard to work efficiency, operator safety, and working conditions, to design a comprehensive Ergonomic Performance Indicator (EPI) for quantitative determination of the ergonomic status and maturity of a given worksystem...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
Banu Sizirici, Berrin Tansel
The development of a systematic approach which can be used as a decision-making tool to extend or shorten the post-closure care (PCC) period requires technically sound and justifiable methods. These methods can incorporate analysis and interpretation of available data and information from closed landfill. Analysis of existing data from closed landfills may present challenges due to variations in the data collection procedures, data analysis methods and reporting methodologies used during active and post-closure periods of a landfill...
February 2012: Waste Management & Research
Nicholas Heyer, Thais C Morata, Lynne E Pinkerton, Scott E Brueck, Daniel Stancescu, Mary Prince Panaccio, Hyoshin Kim, J Stephen Sinclair, Martha A Waters, Cherie F Estill, John R Franks
OBJECTIVES: To evaluate the effectiveness of hearing conservation programs (HCP) and their specific components in reducing noise-induced hearing loss (NIHL). METHODS: This retrospective cohort study was conducted at one food-processing plant and two automotive plants. Audiometric and work-history databases were combined with historical noise monitoring data to develop a time-dependent exposure matrix for each plant. Historical changes in production and HCP implementation were collected from company records, employee interviews and focus groups...
July 2011: Occupational and Environmental Medicine
Maria C Jaimes, Holden T Maecker, Ming Yan, Vernon C Maino, Mary Beth Hanley, Angela Greer, Janice M Darden, M Patricia D'Souza
When evaluating candidate prophylactic HIV and cancer vaccines, intracellular cytokine staining (ICS) assays that measure the frequency and magnitude of antigen-specific T-cell subsets are one tool to monitor immunogen performance and make product advancement decisions. To assess the inter-laboratory assay variation among multiple laboratories testing vaccine candidates, the NIH/NIAID/DAIDS in collaboration with BD Biosciences implemented an ICS Quality Assurance Program (QAP). Seven rounds of testing have been conducted in which 16 laboratories worldwide participated...
January 5, 2011: Journal of Immunological Methods
A C Hambly, R K Henderson, M V Storey, A Baker, R M Stuetz, S J Khan
Dual distribution systems are becoming increasingly common in greenfield housing developments in Australia for the redistribution of recycled water to households for non-potable use. Within such schemes there exists the potential for cross-connections between recycled and drinking water systems. Due to the high level of recycled water treatment, these events are unlikely to lead to outbreaks of illness in the community. Nonetheless, they do represent a breach of the recycled water risk management strategy and therefore an elevated level of risk to consumers...
October 2010: Water Research
Steven J Lehotay, Robert A Gates
Unlike quantitative analysis, which must commonly undergo an extensive method validation process in labs to assure quality of results, the quality of the qualitative results in the analysis of pesticide residues in food is generally ignored in practice. Instead, chemists tend to rely on advanced MS techniques and general subjective guidelines or fixed acceptability criteria when making analyte identifications. All analytes and matrices have unique characteristics that make this current approach less effective than desirable in many real-world situations...
November 2009: Journal of Separation Science
William Egan, Timothy Schofield
An understanding of the principles of degradation, as well as the statistical tools for measuring product stability, is essential to management of product quality. Key to this is management of vaccine potency. Vaccine shelf life is best managed through determination of a minimum potency release requirement, which helps assure adequate potency throughout expiry. Use of statistical tools such a least squares regression analysis should be employed to model potency decay. The use of such tools provides incentive to properly design vaccine stability studies, while holding stability measurements to specification presents a disincentive for collecting valuable data...
November 2009: Biologicals: Journal of the International Association of Biological Standardization
Yongnian Ni, Yanhua Lai, Sarina Brandes, Serge Kokot
Multi-wavelength fingerprints of Cassia seed, a traditional Chinese medicine (TCM), were collected by high-performance liquid chromatography (HPLC) at two wavelengths with the use of diode array detection. The two data sets of chromatograms were combined by the data fusion-based method. This data set of fingerprints was compared separately with the two data sets collected at each of the two wavelengths. It was demonstrated with the use of principal component analysis (PCA), that multi-wavelength fingerprints provided a much improved representation of the differences in the samples...
August 11, 2009: Analytica Chimica Acta
Zongwei Cai, Guibin Jiang
Soil samples collected from an electronic waste recycling site were prepared by using Soxhlet extraction and multiple-step column chromatographic clean-up. Gas chromatography/ion trap mass spectrometry method was developed to determine polybrominated diphenyl ethers (PBDEs) in the sample extracts. The method performance was evaluated by the recovery of (13)C-labeled internal standards and by analyzing quality assurance and quality control samples. Relative error and relative standard deviation obtained from the analysis of duplicated samples and spiked matrix were better than 10%...
August 15, 2006: Talanta
William Graham Wood
External quality assessment surveys for thyroid-related antibodies have been offered by INSTAND for 20 years. During this time, some problems have remained, especially those between the similarity of samples sent and routine patient samples. Here the questions of "matrix effects" and "commutability of results" are topics discussed at most EQA-meetings. This short communication deals with the effects of lyophilization on results for thyroid-associated antibodies in an EQA-survey carried out by over 230 participants in October 2005 by INSTAND in Düsseldorf, Germany...
2007: Clinical Laboratory
Alex J Rai, Craig A Gelfand, Bruce C Haywood, David J Warunek, Jizu Yi, Mark D Schuchard, Richard J Mehigh, Steven L Cockrill, Graham B I Scott, Harald Tammen, Peter Schulz-Knappe, David W Speicher, Frank Vitzthum, Brian B Haab, Gerard Siest, Daniel W Chan
There is a substantial list of pre-analytical variables that can alter the analysis of blood-derived samples. We have undertaken studies on some of these issues including choice of sample type, stability during storage, use of protease inhibitors, and clinical standardization. As there is a wide range of sample variables and a broad spectrum of analytical techniques in the HUPO PPP effort, it is not possible to define a single list of pre-analytical standards for samples or their processing. We present here a compendium of observations, drawing on actual results and sound clinical theories and practices...
August 2005: Proteomics
M S Al-Masri, A Aba, A Al-Hamwi, A Shakhashiro
An in-house reference soil sample containing high levels of naturally occurring radioactive materials collected from contaminated areas in the Syrian oilfields has been prepared as a part of the quality assurance program in AECS. Homogeneity of the sample has been examined using three methods, viz. particle size distribution of the sample matrix, total alpha/beta counting and gamma spectrometry. In conjunction with Dixon and Grubb tests as statistical tools, ten random samples from the original sample were used for this investigation...
December 2004: Applied Radiation and Isotopes
T P Conrads, V A Fusaro, S Ross, D Johann, V Rajapakse, B A Hitt, S M Steinberg, E C Kohn, D A Fishman, G Whitely, J C Barrett, L A Liotta, E F Petricoin, T D Veenstra
Serum proteomic pattern diagnostics is an emerging paradigm employing low-resolution mass spectrometry (MS) to generate a set of biomarker classifiers. In the present study, we utilized a well-controlled ovarian cancer serum study set to compare the sensitivity and specificity of serum proteomic diagnostic patterns acquired using a high-resolution versus a low-resolution MS platform. In blinded testing sets, the high-resolution mass spectral data contained multiple diagnostic signatures that were superior to the low-resolution spectra in terms of sensitivity and specificity (P<0...
June 2004: Endocrine-related Cancer
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