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K Azma, S A Raeissadat, A Hosseini, H Mahmoudi, M Sepehrian, Z Salehi
OBJECTIVE: To delineate H-reflex parameters and specify the diagnostic accuracy measures of thenar muscle H-reflex in Fibromyalgia (FM). METHODS: The study was a cross sectional study performed on 30 subjects with FM and 30 healthy volunteers in two major referral hospitals. We recorded the number of obtainable thenar H-reflexes and their minimum latency, threshold and amplitude in each group. RESULTS: There was a significantly more chance to elicit the H-reflex in patients with FM...
April 2016: Acta Reumatológica Portuguesa
Arnab Samanta
We perform an inviscid, spatial stability analysis of supersonic, heated round jets with the mean properties assumed uniform on either side of the jet shear layer, modelled here via a cylindrical vortex sheet. Apart from the hydrodynamic Kelvin-Helmholtz (K-H) wave, the spatial growth rates of the acoustically coupled supersonic and subsonic instability waves are computed for axisymmetric conditions (m=0) to analyse their role on the jet stability, under increased heating and compressibility. With the ambient stationary, supersonic instability waves may exist for any jet Mach number M j ≥2, whereas the subsonic instability waves, in addition, require the core-to-ambient flow temperature ratio T j /T o >1...
April 2016: Proceedings. Mathematical, Physical, and Engineering Sciences
Kamran Azma, Seyyed Ahmad Raeissadat, Alireza Hosseini, Hooman Mahmoudi, Mohammad Hosein Sepehrian, Zahra Salehi
OBJECTIVE: To delineate H-reflex parameters and specify the diagnostic accuracy measures of thenar muscle H-reflex in Fibromyalgia (FM). METHODS: The study was a cross sectional study performed on 30 subjects with FM and 30 healthy volunteers in two major referral hospitals. We recorded the number of obtainable thenar H-reflexes and their minimum latency, threshold and amplitude in each group. RESULTS: There was a significantly more chance to elicit the H-reflex in patients with FM...
January 3, 2016: Acta Reumatológica Portuguesa
Guillaume Caron, Tanguy Marqueste, Patrick Decherchi
The purpose of this study was to evaluate the effects of aging and chronic physical activity on the postactivation depression of the Hoffman reflex (H-reflex). The maximal amplitude H wave/maximal amplitude M wave ratio was measured, and the rate-sensitive depression of the H-reflex was assessed. Measurements were performed on sedentary rats aged of 3, 6, 12, and 20 months and on animals aged of 12 and 20 months performing an incremental treadmill exercise protocol during the last eight weeks preceding the recordings...
June 2016: Neurobiology of Aging
Katsuhiro Furukawa, Takayuki Fujiwara, Koji Abe, Masayosi Kamijo
The aim of this study was to measure the H wave by using voice-activated electromyography to reveal how different speech outputs affect the spinal cord segments innervating the lower limb skeletal muscles. In 21 healthy adults (16 men and 5 women) seated in a semi-reclined position, the H wave was recorded using surface electrodes over the soleus muscle of the pivot leg after stimulating the tibial nerve. The amplitude of the H wave was 1.02 SD 0.69 mV under the pre-vocalization condition; 1.51 SD 0.76 mV under the submaximal vocalization condition (≥60-<80 dB); and 1...
2016: Physiotherapy Theory and Practice
Sarah Kneis, Anja Wehrle, Kathrin Freyler, Katrin Lehmann, Britta Rudolphi, Bernd Hildenbrand, Hans Helge Bartsch, Hartmut Bertz, Albert Gollhofer, Ramona Ritzmann
OBJECTIVE: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. Resulting sensory and motor dysfunctions often lead to functional impairments like gait or balance disorders. As the underlying neuromuscular mechanisms are not fully understood, we compared balance performance of CIPN patients with healthy controls (CON) to specify differences responsible for postural instability. METHODS: 20 breast cancer patients with CIPN (PAT) and 16 matched CONs were monitored regarding centre of pressure displacement (COP) and electromyographic activity of M...
February 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Dae Hyun Kim, Ji Cheol Shin, Seungsoo Jung, Tae-Min Jung, Deog Young Kim
Spasticity is a common cause of long-term disability in poststroke hemiplegic patients. We investigated whether intermittent theta burst stimulation (iTBS) could reduce upper-limb spasticity after a stroke. Fifteen hemiplegic stroke patients were recruited for a double-blind sham-controlled cross-over design study. A single session of iTBS or sham stimulation was delivered on the motor hotspot of the affected flexor carpi radialis muscle in a random and counterbalanced order with a 1-week interval. Modified Ashworth scale (MAS), modified Tardieu scale (MTS), H-wave/M-wave amplitude ratio, peak torque (PT), peak torque angle (PTA), work of affected wrist flexor, and rectified integrated electromyographic activity of the flexor carpi radialis muscle were measured before, immediately after, 30 min after, and 1 week after iTBS or sham stimulation...
July 8, 2015: Neuroreport
C G Jolivalt, M Rodriguez, J Wahren, N A Calcutt
AIMS: To investigate the efficacy of a pegylated C-peptide (Peg-C-peptide) against indices of peripheral neuropathy in a mouse model of type 1 diabetes and to compare efficacy of this C-peptide analogue against that of the native molecule. METHODS: C57Bl/6 mice were injected with two consecutive doses of streptozotocin (STZ) to induce type 1 diabetes. Mice were treated twice daily with native C-peptide [0.4-1.3 mg/kg subcutaneously (s.c.)] or twice weekly with Peg-C-peptide (0...
August 2015: Diabetes, Obesity & Metabolism
Anteneh M Feyissa, Sudhakar Tummala
The aim of this study was examine the role of Hoffmann reflex (H-reflex) monitoring in identifying intraoperative spinal cord injury and predicting postoperative neurological outcome in patients undergoing thoracic spine surgery. Despite the physiologic basis for the use of H-reflex to monitor spinal motor pathways, there are only a few reports highlighting its application as an intraoperative neuromonitoring tool. We retrospectively reviewed the electronic medical records of 19 consecutive patients who underwent thoracic spine surgery for metastatic thoracic spinal tumors between 2011 and 2013 at the MD Anderson Cancer Center...
June 2015: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Yujiro Masu, Ken Muramatsu
[Purpose] This study aimed to clarify the characteristics of motor neuron excitability by examining the soleus H-reflex in the ready position adopted immediately before making a return during badminton games. [Subjects] Sixteen individuals with (badminton group) and 16 without (control group) experience of playing badminton were studied. [Methods] Each subject was instructed to take up various stances for returning a shuttlecock to measure the H- and M-waves in the soleus. [Results] The H-wave was significantly decreased when gripping a racket was held in the dominant hand than compared to just standing in the badminton group...
January 2015: Journal of Physical Therapy Science
Michelle C Potter, Krystyna M Wozniak, Noelle Callizot, Barbara S Slusher
Pyridoxine is used as a supplement for treating conditions such as vitamin deficiency as well as neurological disorders such as depression, epilepsy and autism. A significant neurologic complication of pyridoxine therapy is peripheral neuropathy thought to be a result of long-term and high dose usage. Although pyridoxine-induced neuropathy is transient and can remit after its withdrawal, the process of complete recovery can be slow. Glutamate carboxypeptidase II (GCP II) inhibition has been shown to improve symptoms of both chemotherapy- and diabetic-induced neuropathy...
2014: PloS One
Christopher C Matthews, Paul S Fishman, George F Wittenberg
INTRODUCTION: Skeletal muscles that are under the influence of tetanus toxin show an exaggerated reflex response to stretch. We examined which changes in the stretch reflex may underlie the exaggerated response. METHODS: H-reflexes were obtained from the tibialis anterior (TA) and flexor digitorum brevis (FDB) muscles in rats 7 days after intramuscular injection of tetanus toxin into the TA. RESULTS: We found effects of the toxin on the threshold, amplitude, and duration of H-waves from the TA...
April 2014: Muscle & Nerve
Matthew D Beekley
The purpose of this study was to examine the effect of changes in capillary blood pH on the resting soleus Hoffmann (H) reflex in the intact human. H-max size, H-wave at 20% of H-max, M-max and H-reflex latency were recorded in 10 subjects (apparently healthy, ages 19-36) before and after exposure to 3 hours of NaHCO(3), CaCO(3), NH(4)Cl (all at 0.3 g/kg) or 10 minutes 7% Carbon dioxide (CO(2)) administration. NaHCO(3) increased capillary blood pH, CaCO(3) did not change capillary blood pH, and NH(4)Cl and 7% CO(2) decreased capillary blood pH...
July 2014: International Journal of Neuroscience
Serena L J Tan, Jia Min Kan, Richard D Webster
The electrochemical reduction mechanisms of flavin mononucleotide (FMN) in buffered aqueous solutions at pH 3-11 and unbuffered aqueous solutions at pH 2-11 were examined in detail using variable-scan-rate cyclic voltammetry (ν = 0.1-20 V s(-1)), controlled-potential bulk electrolysis, UV-vis spectroscopy, and rotating-disk-electrode voltammetry. In buffered solutions at pH 3-5, FMN undergoes a two-electron/two-proton (2e(-)/2H(+)) reduction to form FMNH2 at all scan rates. When the buffered pH is increased to 7-9, FMN undergoes a 2e(-) reduction to form FMN(2-), which initially undergoes hydrogen bonding with water molecules, followed by protonation to form FMNH(-)...
November 7, 2013: Journal of Physical Chemistry. B
Katarzyna Pawlak-Osińska, Wojciech Kaźmierczak, Henryk Kaźmierczak, Małgorzata Wierzchowska, Izabela Matuszewska
OBJECTIVE: The goal of this study was to observe spontaneous cortical activity and cortical activity modulated by tinnitus-matched sound in tinnitus patients and healthy subjects with no otoneurologic symptoms. METHOD: Data were prospectively collected from 50 tinnitus patients and 25 healthy subjects. Cortical activity was recorded in all subjects with eyes closed and open and during photostimulation, hyperventilation and acoustic stimulation using 19-channel quantitative electroencephalography...
April 2013: Clinics
Matthew S Thiese, Matthew Hughes, Jeremy Biggs
BACKGROUND: Non-invasive electrotherapy is commonly used for treatment of chronic low back pain. Evidence for efficacy of most electrotherapy modalities is weak or lacking. This study aims to execute a high-quality, double-blinded randomized controlled clinical trial comparing 1) H-Wave(®) Device stimulation plus usual care with 2) transcutaneous electrical nerve stimulation (TENS) plus usual care, and 3) Sham electrotherapy plus usual care to determine comparative efficacy for treatment of chronic non-specific low back pain patients...
2013: BMC Musculoskeletal Disorders
Hao Ren, Rui-Ling Zhou, Chong-Tan Zhou
The aim of the present study was to establish a minimally invasive H reflex model in mice for the benefit of the research of clinical spinal cord injury and related diseases. Minimally invasive surgery was performed in hind limb of Kunming mouse under light anesthesia. The skin was incised at the point of one-third of the distance from greater trochanter to the base of the cauda. A pair of fine copper conductors were inserted into the shallow muscle using a syringe needle. After the needles were withdrawed, the retained conductors were ligated and fixed with the tissues surrounding the sciatic nerve as the first pair of stimulating electrodes...
August 25, 2012: Sheng Li Xue Bao: [Acta Physiologica Sinica]
Thomas L Smith, Michael F Callahan, Kenneth Blum, Nicholas A Dinubile, Thomas J H Chen, Roger L Waite
Effects of repeated H-Wave® device stimulation (HWDS) on blood flow and angiogenesis in the rat hind limb were studied. The hypothesis tested was that HWDS acutely increases hind limb blood flow, and that repeated HWDS would elicit angiogenesis. Animals were HWDS-conditioned (``Conditioned'') or sham-stimulated (``Sham'') (n = 5/group) daily for 3 weeks. The contralateral limb in both groups served as the control. Each animal was injected with bromodeoxyuridine (BrDU). After 3 weeks, rats were anesthetized and iliac artery blood flow was measured bilaterally before, during, and after acute HWDS...
2011: Journal of Surgical Orthopaedic Advances
Sidney Grosprêtre, Alain Martin
The Hoffmann reflex has been the tool most commonly used in exercise studies to investigate modulations in spinal excitability. However, the evolution of electromyographic responses with the increase in stimulation intensity has rarely been assessed when the muscle is active. The purpose of this study was thus to identify that part of the recruitment curve at which the investigation of the Hoffmann reflex is the most reliable in assessing spinal excitability during muscle contraction. Two recruitment curves were determined from the soleus and the medialis gastrocnemius, in passive and active (50% of maximal isometric voluntary contraction) conditions...
March 2012: Journal of Neurophysiology
Carolina Vila-Chã, Deborah Falla, Miguel Velhote Correia, Dario Farina
This study examined the effects of 3 wk of either endurance or strength training on plasticity of the neural mechanisms involved in the soleus H reflex and V wave. Twenty-five sedentary healthy subjects were randomized into an endurance group (n = 13) or strength group (n = 12). Evoked V-wave, H-reflex, and M-wave recruitment curves, maximal voluntary contraction (MVC), and time-to-task-failure (isometric contraction at 40% MVC) of the plantar flexors were recorded before and after training. Following strength training, MVC of the plantar flexors increased by 14...
January 2012: Journal of Applied Physiology
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