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Margaret Brunton, Catherine Cook
BACKGROUND: Several earlier studies have provided evidence of the difficulties nurses have had adapting to foreign workplaces, however few have considered wider perspectives of the workplace communication environment. OBJECTIVE: The aim of this study was to examine the viewpoints and experience of both New Zealand qualified nurses and internationally qualified nurses in managing communication within teams and the clinical practice context in an increasingly diverse healthcare workplace in New Zealand...
April 6, 2018: International Journal of Nursing Studies
Wenpeng Wang, Wenyun Zheng, Fengzhi Hu, Xiujuan He, Dong Wu, Wenliang Zhang, Haipeng Liu, Xingyuan Ma
Chinese hamster ovary (CHO) cells are the famous expression system for industrial production of recombinant proteins, such as therapeutic antibodies. However, there retained still bottlenecks in protein quality and weakness in expression efficiency because of the intrinsic genetic properties of the cell. Here we have enhanced biosynthesis performance of heterologous proteins in CHO-K1 cell using CRISPR-Cas9 by editing the genome precisely with two genes for improving ER microenvironment and reinforcing anti-apoptotic ability...
April 23, 2018: ACS Synthetic Biology
Shayne C Gad, JoAnn C L Schuh
Safety ("biocompatibility") assessment of medical devices has evolved along a different path than that of drugs, being historically governed more by the considerations and needs of engineers rather than chemists and biologists. As a result, the involvement of veterinary pathologists has been much more limited-almost entirely to evaluating tissue responses in tissues in direct contact with implanted devices. As devices have become more complex in composition, structure, placement, and use, concerns as to adverse systemic responses in patients have called for more comprehensive and thoughtful evaluations of effects throughout the body...
January 1, 2018: Toxicologic Pathology
Ricardo Roque
This essay traces the connected histories of Portuguese and French anthropology in the late nineteenth century. By looking at a Portuguese scientific institution, the Carlos Ribeiro Society, it considers how French race science, known as anthropologie, was adopted and adapted across the European Latin world as a type of "stranger-science." That is: as an authoritative outsider scientific formation, installed into national terrain in accordance with insider strategies for turning foreign elements into native forms of scientific sovereignty and modernity...
April 1, 2018: History of Science; An Annual Review of Literature, Research and Teaching
Yingjiang Ye, Fan Liu
Anastomotic leakage is a common and severe postoperative complication foollowing sphincter-preserving surgery of rectal cancer. Many useful studies on anastomotic leakage were conducted both in our country and abroad. However, the lack of standardized and influential definition and diagnostic criteria is responsible for confusion in the literature. In this paper, the history of studies on the definition and diagnostic criteria of anastomotic leakage is reviewed, and the name evolution process of anastomotic leakage in domestic and foreign studies is introduced...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
S F Bwatota, M Makungu, H E Nonga
A cross-sectional study was conducted to determine the occurrence of indigestible foreign bodies (IFB) in cattle slaughtered at Morogoro Municipal Slaughterhouse, Tanzania. A total of 387 slaughter cattle were examined for presence of IFB. Out of 387 examined cattle, 93 (24.03%) had IFB in their forestomachs. The observed IFB were plastic bags, fruit seeds, clothing materials, ropes, hairballs, leather materials, stones, metallic nails, and wire. Plastic bags were the most frequently (50.5%) observed IFB followed by fruit seeds (18...
2018: Journal of Veterinary Medicine
Amir Alireza Rasouli-Ghahroudi, Amirreza Rokn, Mohammad Abdollahi, Fatemeh Mashhadi-Abbas, Siamak Yaghobee
Background: This study aims to analyze the effect of Semelil, an herbal selenium-based medicine, on osteogenesis in rabbit calvarium defects. Methods: Four identical bony defects (8 mm) were created in the calvarium of 16 New Zealand male rabbits and filled randomly with xenogenic bone substitute material (Bio-Oss®) and semelil herbal drug (ANGIPARS™). One site was filled with Bio-Oss (B); the second site was treated with ANGIPARS (A); the third site was treated with ANGIPARS + Bio-Oss (AB); and the fourth site was left as untreated control (C) and defects were left unfilled...
2018: BioMed Research International
Shalini Hegde, Umesh Bahadur, Ravi Prakash Kanojia, Monika Bawa, Ram Samujh
Aim: Airway foreign body (FB) is a very common pediatric surgical emergency. On certain difficult occasions, the extraction of FB with optical forceps (OFs) is difficult. These conditions create a life-threatening scenario. We present some of the alternative methods of FB extraction for these situations. Patients and Methods: This is a retrospective case review of patients presenting to pediatric emergency with airway FB. All patients had a chest X-ray done before the procedure...
April 2018: Journal of Indian Association of Pediatric Surgeons
Lilia Arguello-Guerra, Estefanía Vargas-Chandomid, Jose Manuel Díaz-González, Silvia Méndez-Flores, Ana Ruelas-Villavicencio, Judith Domínguez-Cherit
Introduction: Surgery is performed more frequently now at days, due to the increasing incidence of melanoma and no-melanoma skin cancer. There are different opinions among dermatologic surgeons between to continue or discontinue antithrombotic therapy prior to the procedure, which increases the risk of thromboembolic events. Prophylaxis with oral antibiotics in the postsurgical period is controversial. Objective: To report the safety of surgery without suspending antithrombotic therapy and without oral antibiotic prophylaxis in dermatology surgery of patients with multiple comorbidities and polypharmacy...
2018: Cirugia y Cirujanos
Marta M Marzi, Miryam S Pires, Nora B Quaglia
OBJECTIVES: To perform a list agreed by Argentinean experts and adapted to the local context containing potentially inappropriate (PI) medications in old people (OP) usingthe Delphi consensus technique optimized for this subject. METHODS: A preliminary list of potentially inappropriate medications (PIM) was drawn up based on foreign PIM lists and a selective search in the scientific literature. The iterative Delphi process was used to submit the active pharmaceutical ingredients (APIs) of the preliminary PIM list to the panel of Argentinean experts...
April 18, 2018: Value in Health Regional Issues
Haihong Fang, Jiao Feng, Yuanhong Xu, Ying Zhang, Zhe Zhan, Zhe Yin, Xiongbo Duan, Bo Gao, Yigang Tong, Jinglin Wang, Yanping Luo, Erhei Dai, Dongsheng Zhou
This study proposed a replicon-based scheme for typing IncX into nine separately clustering subgroups, including IncX1α, IncX1β and IncX2-8. The complete nucleotide sequences of three IncX8 plasmids, namely pT5282-CTXM and p30860-NR from Enterobacter cloacae and p13190-KPC from Klebsiella pneumoniae, were determined and compared with all the other two previously sequenced IncX8 plasmids pCAV1043-58 and pCAV1741-16. These five plasmids possessed conserved IncX8 backbones with limited genetic variations with respect to gene content and organization, and each of them carried one or three accessory modules that harbored resistance markers and metabolic gene clusters as well as transposons, insertion sequence (IS)-based transposition units and miniature inverted repeat transposable elements, indicating that the relatively small IncX8 backbones were able to integrate various foreign genetic contents...
April 18, 2018: International Journal of Antimicrobial Agents
Yasufumi Kawasaki, Kazuya Sato, Hiroko Hayakawa, Norihito Takayama, Hirofumi Nakano, Ryoji Ito, Kiyomi Mashima, Iekuni Oh, Daisuke Minakata, Ryoko Yamasaki, Kaoru Morita, Masahiro Ashizawa, Chihiro Yamamoto, Kaoru Hatano, Shin-Ichiro Fujiwara, Ken Ohmine, Kazuo Muroi, Yoshinobu Kanda
Xenogeneic graft-versus-host disease (GVHD) models in highly immunodeficient mice are currently being used worldwide to investigate human immune responses against foreign antigens in vivo. However, the individual roles of CD4+ and CD8+ T-cells, and donor/host hematopoietic and non-hematopoietic antigen-presenting cells (APCs) in the induction and development of GVHD have not been fully investigated. In the present study, we comprehensively investigated the immune responses of human T-cells and the antigen presentation capacity of donor/host hematopoietic and non-hematopoietic APCs in xenogeneic GVHD models using NOD/Shi-scid-IL2rgnull (NOG) mice...
April 17, 2018: Biology of Blood and Marrow Transplantation
Jeffrey A Steinberg, Jayson Sack, Bayard Wilson, David Weingarten, Bob Carter, Alexander Khalessi, Sharona Ben-Haim, John Alksne
OBJECTIVE Trigeminal neuralgia is a debilitating pain disorder most often caused by arterial compression of the trigeminal nerve, although there are other etiologies. Microvascular decompression (MVD) remains the most definitive treatment for this disorder, with cure rates reported between 60% and 80%. Traditional MVD techniques involve a retrosigmoid craniotomy with placement of an inert foreign material, such as Teflon, between the nerve and compressive vessel. Recurrence of trigeminal neuralgia after MVD has been associated with vessel migration, adhesion formation, and arterial pulsation against the Teflon abutting the nerve...
April 20, 2018: Journal of Neurosurgery
Raghav Ravani, Rohan Chawla, Shorya Vardhan Azad, Yogita Gupta, Vinod Kumar, Atul Kumar
Purpose: The objective of this study is to describe the removal of retained intraocular foreign body (RIOFB) by bimanual pars plana vitrectomy through midline sclerotomy in phakic patients. Technique: Four eyes with RIOFB and clear lens underwent microincision vitrectomy surgery. A chandelier illumination was placed through one of the existing ports. The foreign body (FB) was localized by direct visualization (intravitreal) or indentation (pars plana), stabilized using an intraocular magnet/FB forceps introduced through a midline sclerotomy and freed of vitreous from all sides using a vitrectomy cutter through the other port bimanually, reoriented along their long axis and extracted through the midline sclerotomy...
May 2018: Indian Journal of Ophthalmology
Anita Ambastha, Rakhi Kusumesh, Gyan Bhasker, Bibhuti Prassan Sinha
Purpose: To study the safety and efficacy of biologic fibrin glue (FG) in comparison with infinity suture in SICS with compromised scleral flap. Methods: A retrospective comparative study of patients who were treated with FG (Group A) with 10-0 nylon (Group B) as sealing agent for intraoperative compromised tunnels in SICS. Parameters noted were postoperative inflammation, wound integrity, anterior chamber (AC) depth, intraocular pressure (IOP), and surgically induced astigmatism (SIA) at postoperative day 1, 4 weeks, 6 weeks, and 6 months, respectively...
May 2018: Indian Journal of Ophthalmology
Ba H Do, Toyoaki Ohbuchi, Tetsuro Wakasugi, Hiroki Koizumi, Mitsuru Yokoyama, Nobusuke Hohchi, Hideaki Suzuki
Background Airway mucociliary transport is an important function for the clearance of inhaled foreign particulates in the respiratory tract. The present study aimed at investigating the regulatory mechanism of acetylcholine (Ach)-induced ciliary beat of the human nasal mucosa in ex vivo. Methods The inferior turbinate mucosa was collected from patients with chronic hypertrophic rhinitis during endoscopic surgery. The mucosa was cut into thin strips, and ciliary movement was observed under a phase-contrast light microscope with a high-speed digital video camera...
January 1, 2018: American Journal of Rhinology & Allergy
Marco Crostelli, Osvaldo Mazza, Massimo Mariani, Dario Mascello, Carlo Iorio
PURPOSE: Bone substitutes' advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes' integration is often incomplete. METHODS: From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft...
April 19, 2018: European Spine Journal
Dina Abdel Salam El-Dakhs, Jeanette Altarriba
Empirical evidence has recently been provided for the distinctiveness of emotion words as compared to abstract and concrete words for monolinguals, calling for a reconsideration of the relation between emotion and language. The present study investigates whether the distinctiveness of emotion words among monolinguals holds for foreign language learners. To this end, three groups (n = 120 per group) of late Arabic-English bilinguals who learned English as a foreign language completed tasks including free recall, rating, and discrete word association...
April 19, 2018: Journal of Psycholinguistic Research
Xiaoyu Liang, Jianwei Duan, Xuanling Li, Xiaowei Zhu, Youlu Chen, Xiaoli Wang, Hongfan Sun, Deling Kong, Chen Li, Jing Yang
Subunit vaccines that are designed based on recombinant antigens or peptides have shown promising potential as viable substitutes for traditional vaccines due to their better safety and specificity. However, the induction of adequate in vivo immune responses with appropriate effectiveness remains a major challenge for vaccine development. More recently, the implementation of a nanoparticle-based antigen delivery system has been considered a promising approach to improve the in vivo efficacy for subunit vaccine development...
April 20, 2018: Nanoscale
Xin Xiao, Leiming Tao, Man Li, Xiaowei Lv, Dekang Huang, Xingxing Jiang, Haiping Pan, Mingkui Wang, Yan Shen
It is highly desirable to develop efficient and low-cost catalysts to minimize the overpotential of the hydrogen evolution reaction (HER) for large-scale hydrogen production from electrochemical water splitting. Doping a foreign element into the host catalysts has been proposed as an effective approach to optimize the electronic characteristics of catalysts and thus improve their electrocatalytic performance. Herein we, for the first time, report vanadium-doped CoP on self-supported conductive carbon cloth (V-CoP/CC) as a robust HER electrocatalyst, which achieves ultra-low overpotentials of 71, 123 and 47 mV to afford a current density of 10 mA cm-2 in 1 M KOH, 1 M PBS and 0...
February 21, 2018: Chemical Science
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