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https://www.readbyqxmd.com/read/28628684/megasessions-efficacy-of-fewer-longer-treatment-sessions-for-fat-reduction-in-noninvasive-body-contouring-using-a-radiofrequency-based-device
#1
Diane Duncan
<p>While the field of noninvasive body contouring is booming, many patients still note a lesser result than they might achieve with a single session of liposuction or dermolipectomy. The duration of a noninvasive fat reduction treatment series can be daunting. Patients have questioned the worth of these procedures when the expected benefit is modest and the time they devote to the project is significant. An eight-patient mini-study was performed to see if two or three "megasessions" could be substituted for eight weekly sessions of bipolar radiofrequency based fat reduction treatments...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28620480/reduction-of-hba1c-levels-by-fucoxanthin-enriched-akamoku-oil-possibly-involves-the-thrifty-allele-of-uncoupling-protein-1-ucp1-a-randomised-controlled-trial-in-normal-weight-and-obese-japanese-adults
#2
Nana Mikami, Masashi Hosokawa, Kazuo Miyashita, Hitoshi Sohma, Yoichi M Ito, Yasuo Kokai
Lifestyle-related problems are becoming a major health threat in East Asian countries. Therefore, finding an efficacious nutraceutical for this population is important. One candidate is fucoxanthin (Fx), a carotenoid abundantly found in edible brown seaweed that has been associated with a number of valuable health-promoting benefits. Unfortunately, clinical studies of Fx are limited. In the present study, we aimed to evaluate the effects of Fx on obesity-related parameters in Japanese subjects harbouring an SNP associated with lifestyle-related problems...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28610410/prognostic-value-of-clinicopathological-factors-for-indonesian-breast-carcinomas-of-different-molecular-subtypes
#3
Irianiwati Widodo, Ery Kus Dwianingsih, Sumadi Lukman Anwar, Triningsih Fx Ediati, Totok Utoro, Teguh Aryandono, Soeripto
Background: Breast carcinoma (BC) is a heterogeneous disease due to its different molecular profiles i.e. luminal (luminal A and luminal B) and non-luminal (HER2 positive and triple negative) subtypes. Prognostic value of clinicopathological factors of Indonesian BC of different molecular subtypes has never been reported previously. This study aims to elaborate prognostic impacts on Indonesian BCs focusing on separate molecular subtypes. Methods: A hundred and fifty cases of invasive BC, stage I-IIIA, in Sardjito Hospital, Indonesia, were stained using anti ER, PR, HER2 and Ki-67 antibodies...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28609196/horizontal-ground-reaction-forces-to-stationary-running-performed-in-the-water-and-on-dry-land-at-different-physiological-intensities
#4
Cristine Lima Alberton, Stephanie Santana Pinto, Gabriela Neves Nunes, Douglas Guerreiro Dos Santos Rau, Paula Finatto, Amanda Haberland Antunes, Marcus Peikriszwili Tartaruga, Marco Bergamin, Eduardo Lusa Cadore, Luiz Fernando Martins Kruel
The aim of the present study was to compare the peak anterior-posterior (Fy) and medio-lateral (Fx) ground reaction forces (GRFs) of women performing stationary running at different intensities in aquatic and dry land environments. Fourteen young women performed the stationary running exercise at three cadences (first ventilatory threshold, second ventilatory threshold and maximum effort, as determined during exercise in water) in aquatic and dry land environments. Two-way repeated measures ANOVA was used to analyse the data (α = ...
June 13, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28608503/acute-radiation-oesophagitis-associated-with-2-deoxy-2-18f-fluoro-d-glucose-uptake-on-positron-emission-tomography-ct-during-chemo-radiation-therapy-in-patients-with-non-small-cell-lung-cancer
#5
Sarah Everitt, Jason Callahan, Eman Obeid, Rodney J Hicks, Michael Mac Manus, David Ball
INTRODUCTION: Acute radiation oesophagitis (ARO) is frequently experienced by patients receiving concurrent chemo-radiation therapy (cCRT) for non-small-cell lung cancer (NSCLC). We investigated ARO symptoms (CTCAE v3.0), radiation dose and oesophageal FDG PET/CT uptake. METHOD: Candidates received cCRT (60 Gy, 2 Gy/fx) and sequential FDG PET/CT (baseline FDG0 , FDGwk2 and FDGwk4 ). Mean and maximum standardized uptake value (SUVmean and SUVmax) and radiation dose (Omean and Omax ) were calculated within the whole oesophagus and seven sub-regions (5-60 Gy)...
June 13, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28598293/stereotactic-body-radiotherapy-for-de-novo-spinal-metastases-systematic-review
#6
Zain A Husain, Arjun Sahgal, Antonio De Salles, Melissa Funaro, Janis Glover, Motohiro Hayashi, Masahiro Hiraoka, Marc Levivier, Lijun Ma, Roberto Martínez-Alvarez, J Ian Paddick, Jean Régis, Ben J Slotman, Samuel Ryu
OBJECTIVE The aim of this systematic review was to provide an objective summary of the published literature pertaining to the use of stereotactic body radiation therapy (SBRT) specific to previously untreated spinal metastases. METHODS The authors performed a systematic review, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, of the literature found in a search of Medline, PubMed, Embase, and the Cochrane Library up to March 2015. The search strategy was limited to publications in the English language...
June 9, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28588789/curative-effect-of-stereotactic-body-radiotherapy-for-unresectable-massive-primary-liver-cancer
#7
Ya-Zheng Dang, Xin Li, Shi-Gao Huang, Wan-Ling Lu, Guodong Wang, Dongxian Zhang, Qian-Yun Wang
The aim of this study was to evaluate the curative effect of gamma knife stereotactic body radiotherapy (SBRT) for unresectable massive primary liver cancer. A total of 69 patients with unresectable massive (>10 cm) primary liver cancer who were treated by SBRT at the Department of Radiation Oncology of the 323 Hospital of People's Liberation Army (Xi'an, China) between October, 2006 and October, 2010, were analyzed. According to the Union for International Cancer Control TNM staging guidelines, the patients were graded as stage T1 (n=8), T2 (n=12), T3 (n=21) and T4 (n=28)...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28587681/pet-ct-guided-dose-painting-versus-ct-based-intensity-modulated-radiation-therapy-in-locoregional-advanced-nasopharyngeal-carcinoma
#8
Feng Liu, Xu-Ping Xi, Hui Wang, Ya-Qian Han, Feng Xiao, Ying Hu, Qian He, Lin Zhang, Qin Xiao, Lin Liu, Le Luo, Yun Li, Yi Mo, Hong-Zhi Ma
BACKGROUND: The effect of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT)-guided dose-painting intensity-modulated radiation therapy (IMRT) in locoregionally advanced nasopharyngeal carcinoma (NPC) is unclear. This study aimed to assess the efficacy and toxicity of such combination. METHODS: From 2012 to 2014, 213 patients with stage III-IVB NPC received chemoradiotherapy by PET/CT-guided DP-IMRT (group A, n = 101) or CT-based IMRT (group B, n = 112)...
January 13, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28574040/-use-of-a-filtering-protective-device-during-angioplasty-and-stenting-of-the-brachiocephalic-trunk
#9
V N Tsygankov, A M Frantsevich
The authors carried out a pilot study aimed at assessing the possibility and efficacy of using filtering systems for protection of cerebral arteries from distal embolism during angioplasty and stenting of the brachiocephalic trunk. A total of five patients presenting with lesions of the brachiocephalic trunk underwent 5 roentgenoendovascular interventions with the use of the filtering protective device Spider FX. Angiographic and clinical success was achieved in 100% of cases. Particles of debris were obtained from the protective device in all cases...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28572606/automated-screening-for-fragile-x-premutation-carriers-based-on-linguistic-and-cognitive-computational-phenotypes
#10
Arezoo Movaghar, Marsha Mailick, Audra Sterling, Jan Greenberg, Krishanu Saha
Millions of people globally are at high risk for neurodegenerative disorders, infertility or having children with a disability as a result of the Fragile X (FX) premutation, a genetic abnormality in FMR1 that is underdiagnosed. Despite the high prevalence of the FX premutation and its effect on public health and family planning, most FX premutation carriers are unaware of their condition. Since genetic testing for the premutation is resource intensive, it is not practical to screen individuals for FX premutation status using genetic testing...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28570781/the-effect-of-antioxidants-on-the-long-term-stability-of-thc-and-related-cannabinoids-in-sampled-whole-blood
#11
Lambert K Sørensen, Jørgen B Hasselstrøm
The stability of cannabinoids is complex, and crucial for the assessment of impaired driving caused by cannabis. Therefore, the effect of antioxidants on the long-term stability of Δ(9) -tetrahydrocannabinol (THC), cannabinol (CBN), cannabidiol (CBD), 11-hydroxy-Δ(9) -tetrahydrocannabinol (THC-OH) and 11-nor-9-carboxy-Δ(9) -tetrahydrocannabinol (THC-COOH) in whole blood samples preserved with fluoride citrate (FC) and fluoride oxalate (FX) mixtures was investigated at different temperatures. The measured concentrations of the cannabinoids in authentic whole blood preserved solely with FC or FX mixtures decreased significantly during prolonged storage at -20°C...
June 1, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28541279/do-the-data-really-support-ordering-fragile-x-testing-as-a-first-tier-test-without-clinical-features
#12
Veronique Weinstein, Pranoot Tanpaiboon, Kimberly A Chapman, Nicholas Ah Mew, Sean Hofherr
PurposeCurrent guidelines recommend first-tier chromosome microarray analysis (CMA) and fragile X syndrome (FX) testing for males with isolated intellectual disabilities/learning delay (ID/LD) and autism spectrum disorders (ASDs).MethodsMales in our clinic with ID/LD or ASD (310) were analyzed for positive results from CMA and/or FX testing.ResultsCMA detected abnormalities in 29% of males with ID/LD and only 9% of males with ASD (including variants of uncertain significance and absence of heterozygosity). When males with ID/LD were tested for FX, the detection rate was 2...
May 25, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28533605/the-change-of-lung-capacity-in-elderly-women-caused-by-life-span
#13
Jaeseok Lee, Taewook Kang, Yundong Yeo, Dongwook Han
[Purpose] Although lung capacity in the elderly is affected by age, little research has been performed studying decreasing lung capacity in relation to increasing life expectancy. The aim of this study was to examine the effects of increased life span on the lung capacity of women. [Subjects and Methods] The subjects of this study were 55 healthy elderly women over 60 years of age who were living in Busan. Subjects were classified in the following age categories: 60s, 70s and 80s. For the pulmonary function test, a spirometry (Pony FX, COSMED Inc...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28517010/suppression-of-near-band-edge-emission-in-specially-engineered-zno-twin-nanorods
#14
Avanendra Singh, Kartik Senapati, Biswarup Satpati, Pratap K Sahoo
We report the synthesis of a unique zinc oxide nanorod structure in which an amorphous ZnO layer is sandwiched between two identical crystalline segments of ZnO. A simple hydrothermal reaction method was used for this purpose, which allowed us to tune the amorphous and crystalline sections of the nanorods via reaction temperature. A systematic study of the morphology and dimensions of the nanorods grown under various conditions was performed using a combination of scanning and transmission electron microscopy...
May 31, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28483635/crystal-structure-of-tissue-factor-in-complex-with-antibody-10h10-reveals-the-signaling-epitope
#15
Alexey Teplyakov, Galina Obmolova, Thomas J Malia, Bingyuan Wu, Yonghong Zhao, Susann Taudte, G Mark Anderson, Gary L Gilliland
Tissue factor (TF) initiates the extrinsic pathway of blood coagulation through sequential binding and activation of coagulation factors VII (FVII) and X (FX). In addition, through activation of G-protein-coupled protease activated receptors (PARs) TF induces cell signaling that is related to cancer, angiogenesis and inflammation. Monoclonal antibodies (mAbs) proved to be a useful tool for studying the interplay between TF signaling and coagulation. MAb 10H10 is unique in that it blocks the signaling pathway and thus inhibits angiogenesis and tumor growth without interfering with coagulation...
May 5, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28473841/contrasting-hydraulic-architectures-of-scots-pine-and-sessile-oak-at-their-southernmost-distribution-limits
#16
Elisabet Martínez-Sancho, Isabel Dorado-Liñán, Uwe G Hacke, Hannes Seidel, Annette Menzel
Many temperate European tree species have their southernmost distribution limits in the Mediterranean Basin. The projected climatic conditions, particularly an increase in dryness, might induce an altitudinal and latitudinal retreat at their southernmost distribution limit. Therefore, characterizing the morphological and physiological variability of temperate tree species under dry conditions is essential to understand species' responses to expected climate change. In this study, we compared branch-level hydraulic traits of four Scots pine and four sessile oak natural stands located at the western and central Mediterranean Basin to assess their adjustment to water limiting conditions...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28466137/bone-material-strength-index-as-measured-by-impact-microindentation-is-low-in-patients-with-fractures-irrespective-of-fracture-site
#17
F Malgo, N A T Hamdy, S E Papapoulos, N M Appelman-Dijkstra
We evaluated the relationship between bone material strength index (BMSi) and fragility fractures, including vertebral fractures. Our data showed that BMSi is low in all fracture patients with low bone mass, independently of whether patients sustained a vertebral or a non-vertebral fracture. INTRODUCTION: Impact microindentation (IMI) is a new technique for the measurement of tissue level properties of cortical bone in vivo. Previous studies showed an association between BMSi and non-vertebral fractures, but an association with vertebral fractures is still being debated...
May 2, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28464697/assessment-of-the-procoagulant-activity-of-microparticles-and-the-protein-z-system-in-patients-undergoing-off-pump-coronary-artery-bypass-surgery
#18
Artur Słomka, Aleksandra Piekuś, Mariusz Kowalewski, Wojciech Pawliszak, Lech Anisimowicz, Ewa Żekanowska
To understand the coagulation changes after off-pump coronary artery bypass (OPCAB) surgery, we evaluated the procoagulant activity of microparticles (MPs) and microparticles exposing tissue factor (MPs-TF), together with the levels of total tissue factor (TF), protein Z (PZ), protein Z-dependent protease inhibitor (ZPI), and factor X (FX) before (first day) and 1 week after surgery (seventh day) in plasma samples from 30 patients. Twenty healthy controls were also included. Compared to the controls, patients scheduled for surgery had significantly higher MPs-TF procoagulant activity and lower TF levels ( P = ...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28460470/a-novel-oncolytic-adenovirus-based-on-simian-adenovirus-serotype-24
#19
Tao Cheng, Yufeng Song, Yan Zhang, Chao Zhang, Jieyun Yin, Yudan Chi, Dongming Zhou
Among the oncolytic virotherapy, an emerging treatment for tumor, adenoviruses are widely used at present in preclinical and clinical trials. Traditionally, oncolytic adenoviruses were developed based on the human adenovirus serotype 5 (AdHu5). However, AdHu5 has the drawbacks of preexisting anti-AdHu5 immunity in most populations, and extensive sequestration of Adhu5 by the liver through hexon, blood coagulation factor X (FX), and FX receptor interactions. To tackle these problems, we explored a novel oncolytic adenovirus AdC7-SP/E1A-ΔE3 for cancer treatment...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28455601/paravertebral-block-catheter-breakage-by-electrocautery-during-thoracic-surgery
#20
Noboru Saeki, Yuki Sugimoto, Yoko Mori, Takahiro Kato, Hirotsugu Miyoshi, Ryuji Nakamura, Tomomichi Koga
Advantages of thoracic paravertebral analgesia (TPA) include placement of the catheter closer to the surgical field; however, the catheter can become damaged during the operation. We experienced a case of intraoperative TPA catheter breakage that prompted us to perform an experiment to investigate possible causes. A 50-year-old male underwent a thoracoscopic lower lobectomy under general anesthesia with TPA via an intercostal approach. Following surgery, it was discovered that the catheter had become occluded, as well as cut and fused, so we reopened the incision and removed the residual catheter...
June 2017: Journal of Anesthesia
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