Joonho Choi, Hyung-Jun Yoon, Jae Hong Park, Yukako Nakagami, Chika Kubota, Toshiya Inada, Takahiro A Kato, Shu-Yu Yang, Sih-Ku Lin, Mian-Yoon Chong, Ajit Avasthi, Sandeep Grover, Roy Abraham Kallivayalil, Andi Jaylangkara Tanra, Kok Yoon Chee, Yu-Tao Xiang, Kang Sim, Afzal Javed, Chay Hoon Tan, Norman Sartorius, Shigenobu Kanba, Naotaka Shinfuku, Yong Chon Park, Seon-Cheol Park
The symptom heterogeneity of schizophrenia is consistent with Wittgenstein's analogy of a language game. From the perspective of precision medicine, this study aimed to estimate the symptom presentation and identify the psychonectome in Asian patients, using data obtained from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics. We constructed a network structure of the Brief Psychiatric Rating Scale (BPRS) items in 1438 Asian patients with schizophrenia. Furthermore, all the BPRS items were considered to be an ordered categorical variable ranging in value from 1-7...
January 3, 2022: Journal of Personalized Medicine