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https://www.readbyqxmd.com/read/29792549/analysis-of-the-effects-of-individual-and-community-level-predictors-on-migrant-children-s-primary-immunization-in-yiwu-city-east-china
#1
Yu Hu, Yaping Chen, Liang Hui, Ying Wang
BACKGROUND: To evaluate the effects of a wide range of individual- and community-level factors on migrant children's primary immunization. METHODS: Migrant children aged 13-24 months (born from 1 June 2013 to 31 May 2014) were surveyed in Yiwu city, in June 2015. Social-demographic factors and vaccination records were collected. Five factors at community-level including community wealth, distance to the nearest immunization clinic, maternal education, antenatal clinic (ANC) visits, and hospital delivery were constructed...
May 24, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29792340/multidisciplinary-care-model-for-hiv-improves-treatment-outcome-a-single-centre-experience-from-the-middle-east
#2
Ali Elgalib, Halima Al-Sawafi, Bina Kamble, Saud Al-Harthy, Qamra Al-Sariri
Multidisciplinary team (MDT) care models have been shown to improve clinical outcomes among HIV patients. We aim to assess the impact of adopting MDT approach in a tertiary HIV clinic in Muscat, Sultanate of Oman. We introduced MDT approach in our HIV centre in January 2016 where existing team members (counsellors, nurses, social workers, pharmacists and doctors) worked together, through care pathways, to support patients as they go through the HIV care continuum from diagnosis to viral suppression. Notes were reviewed for demographics and clinical data...
May 24, 2018: AIDS Care
https://www.readbyqxmd.com/read/29792231/high-burden-of-birthweight-lowering-genetic-variants-in-africans-and-asians
#3
Fasil Tekola-Ayele, Tsegaselassie Workalemahu, Azmeraw T Amare
BACKGROUND: Birthweight is an important predictor of infant morbidity and mortality, and is associated with cardiovascular diseases, obesity, and diabetes in childhood and adulthood. Birthweight and fetal growth show regional and population variations even under similar maternal conditions, and a large proportion of these differences are not explained by environmental factors. Whether and to what extent population genetic variations at key birthweight-associated loci account for the residual birthweight disparities not explained by environmental determinants is unknown...
May 24, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29792207/metagenomic-analysis-of-viruses-associated-with-maize-lethal-necrosis-in-kenya
#4
Mwathi Jane Wamaitha, Deepti Nigam, Solomon Maina, Francesca Stomeo, Anne Wangai, Joyce Njoki Njuguna, Timothy A Holton, Bramwel W Wanjala, Mark Wamalwa, Tanui Lucas, Appolinaire Djikeng, Hernan Garcia-Ruiz
BACKGROUND: Maize lethal necrosis is caused by a synergistic co-infection of Maize chlorotic mottle virus (MCMV) and a specific member of the Potyviridae, such as Sugarcane mosaic virus (SCMV), Wheat streak mosaic virus (WSMV) or Johnson grass mosaic virus (JGMV). Typical maize lethal necrosis symptoms include severe yellowing and leaf drying from the edges. In Kenya, we detected plants showing typical and atypical symptoms. Both groups of plants often tested negative for SCMV by ELISA...
May 23, 2018: Virology Journal
https://www.readbyqxmd.com/read/29791440/cost-effectiveness-of-dog-rabies-vaccination-programs-in-east-africa
#5
Rebekah H Borse, Charisma Y Atkins, Manoj Gambhir, Eduardo A Undurraga, Jesse D Blanton, Emily B Kahn, Jessie L Dyer, Charles E Rupprecht, Martin I Meltzer
BACKGROUND: Dog rabies annually causes 24,000-70,000 deaths globally. We built a spreadsheet tool, RabiesEcon, to aid public health officials to estimate the cost-effectiveness of dog rabies vaccination programs in East Africa. METHODS: RabiesEcon uses a mathematical model of dog-dog and dog-human rabies transmission to estimate dog rabies cases averted, the cost per human rabies death averted and cost per year of life gained (YLG) due to dog vaccination programs (US 2015 dollars)...
May 23, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29791048/long-term-course-of-inflammatory-bowel-disease-after-the-great-east-japan-earthquake
#6
Teruko Miyazawa, Hisashi Shiga, Yoshitaka Kinouchi, Seiichi Takahashi, Gen Tominaga, Hiroki Takahashi, Sho Takagi, Nobuya Obana, Tatsuya Kikuchi, Shinya Omori, Yuichirou Sato, Shuichiro Takahashi, Ken Umemura, Katsuya Endo, Yoichi Kakuta, Masaki Matsuura, Tomoya Kimura, Masatake Kuroha, Tooru Shimosegawa
BACKGROUND AND AIM: This study analyzed inflammatory bowel disease activity for two years after the Great East Japan Earthquake. METHODS: We compared the relapse rates of patients with ulcerative colitis or Crohn's disease 1 and 2 years after the earthquake with rates immediately after the earthquake. To evaluate continuous disease courses, we also performed multivariate time-to-event analyses from the time of the earthquake to the onset of additional treatments...
May 23, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29790874/point-of-care-whole-exome-sequencing-of-idiopathic-male-infertility
#7
Khalid A Fakhro, Haitham Elbardisi, Mohamed Arafa, Amal Robay, Juan L Rodriguez-Flores, Alya Al-Shakaki, Najeeb Syed, Jason G Mezey, Charbel Abi Khalil, Joel A Malek, Abdulla Al-Ansari, Sami Al Said, Ronald G Crystal
PurposeNonobstructive azoospermia (NOA) affects 1% of the male population; however, despite state-of-the-art clinical assessment, for most patients the cause is unknown. We capitalized on an analysis of multiplex families in the Middle East to identify highly penetrant genetic causes.MethodsWe used whole-exome sequencing (WES) in 8 consanguineous families and combined newly discovered genes with previously reported ones to create a NOA gene panel, which was used to identify additional variants in 75 unrelated idiopathic NOA subjects and 74 fertile controls...
April 12, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29790872/genomic-sequencing-identifies-secondary-findings-in-a-cohort-of-parent-study-participants
#8
Michelle L Thompson, Candice R Finnila, Kevin M Bowling, Kyle B Brothers, Matthew B Neu, Michelle D Amaral, Susan M Hiatt, Kelly M East, David E Gray, James M J Lawlor, Whitley V Kelley, Edward J Lose, Carla A Rich, Shirley Simmons, Shawn E Levy, Richard M Myers, Gregory S Barsh, E Martina Bebin, Gregory M Cooper
PurposeClinically relevant secondary variants were identified in parents enrolled with a child with developmental delay and intellectual disability.MethodsExome/genome sequencing and analysis of 789 "unaffected" parents was performed.ResultsPathogenic/likely pathogenic variants were identified in 21 genes within 25 individuals (3.2%), with 11 (1.4%) participants harboring variation in a gene defined as clinically actionable by the American College of Medical Genetics and Genomics. These 25 individuals self-reported either relevant clinical diagnoses (5); relevant family history or symptoms (13); or no relevant family history, symptoms, or clinical diagnoses (7)...
April 12, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29790669/genetically-determined-height-was-associated-with-lung-cancer-risk-in-east-asian-population
#9
Lu Wang, Mingtao Huang, Hui Ding, Guangfu Jin, Liang Chen, Feng Chen, Hongbing Shen
The association between adult height and risk of lung cancer has been investigated by epidemiology studies, but the results are inconsistent. Mendelian randomization (MR) analyses with individual-level data from two genome-wide association studies, including a total of 7127 lung cancer cases and 6818 controls, were carried out to explore whether adult height is causally associated with risk of lung cancer. A weighted genetic risk score (wGRS) was created based on genotypes of 101 known height-associated genetic variants...
May 23, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29790236/forecasting-zoonotic-cutaneous-leishmaniasis-using-meteorological-factors-in-eastern-fars-province-iran-a-sarima-analysis
#10
Hamid Reza Tohidinik, Mehdi Mohebali, Mohammad Ali Mansournia, Sharareh R Niakan Kalhori, Mohsen Ali-Akbarpour, Kamran Yazdani
OBJECTIVES: To predict the occurrence of zoonotic cutaneous leishmaniasis (ZCL) and evaluate the effect of climatic variables on disease incidence in the east of Fars province, Iran using the Seasonal Autoregressive Integrated Moving Average (SARIMA) model. METHODS: The Box-Jenkins approach was applied to fit the SARIMA model for ZCL incidence from 2004 to 2015. Then the model was used to predict the number of ZCL cases for the year 2016. Finally, we assessed the relation of meteorological variables (rainfall, rainy days, temperature, hours of sunshine and relative humidity) with ZCL incidence...
May 22, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29790059/characteristics-of-distribution-of-mycobacterium-tuberculosis-lineages-in-china
#11
Haixia Chen, Li He, Chao Cai, Jingyi Liu, Junnan Jia, Liang Ma, Hairong Huang, Lixia Wang, Xumin Ni, Jimin Gao, Weimin Li
The genotyping methods of Mycobacterium tuberculosis would dramatically improve our understanding of the molecular epidemiology of tuberculosis. 3,929 isolates, from a National Survey of Drug-Resistant Tuberculosis in 2007 in China, were successfully genotyped by large sequence polymorphisms and 15 loci variable number tandem repeats. We found that 2,905 (2,905/3,929, 73.9%) cases belonged to Lineage 2, dominated in the east and central regions, 975 cases (975/3,929, 24.8%) were Lineage 4, highly prevailed in the west regions, and 36 and 13 cases were Lineage 3 and Lineage 1, respectively...
March 21, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29789642/spatial-and-temporal-variations-of-particulate-organic-carbon-in-the-yellow-bohai-sea-over-2002-2016
#12
Hang Fan, Xiujun Wang, Haibo Zhang, Zhitong Yu
The Yellow-Bohai Sea (YBS) is a typical marginal sea in the Northwest Pacific Ocean; however, little is known about the dynamics of particulate organic carbon (POC) and underlying mechanisms. Here, we analyze the spatial and temporal variations of surface POC derived from MODIS-Aqua during 2002-2016. Overall, POC is higher in the Bohai Sea (315-588 mg m-3 ) than in the Yellow Sea (181-492 mg m-3 ), and higher in the nearshore than in the offshore. Surface POC is highest in spring in the YBS, and lowest in winter (summer) in the Bohai Sea (the Yellow Sea)...
May 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29789537/detection-of-japanese-encephalitis-virus-rna-in-human-throat-samples-in-laos-a-pilot-study
#13
Tehmina Bharucha, Onanong Sengvilaipaseuth, Malee Seephonelee, Malavanh Vongsouvath, Manivanh Vongsouvath, Sayaphet Rattanavong, Géraldine Piorkowski, Marc Lecuit, Christopher Gorman, Jean-David Pommier, Paul N Newton, Xavier de Lamballerie, Audrey Dubot-Pérès
Japanese encephalitis virus (JEV) is the most commonly identified cause of acute encephalitis syndrome (AES) in Asia. The WHO recommended test is anti-JEV IgM-antibody-capture-enzyme-linked-immunosorbent-assay (JEV MAC-ELISA). However, data suggest this has low positive predictive value, with false positives related to other Flavivirus infections and vaccination. JEV RT-PCR in cerebrospinal fluid (CSF) and/or serum is highly specific, but is rarely positive; 0-25% of patients that fulfil the WHO definition of JE (clinical Acute Encephalitis Syndrome (AES) and JEV MAC-ELISA positive)...
May 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29789456/human-health-risk-assessment-of-toxic-elements-in-farmland-topsoil-with-source-identification-in-jilin-province-china
#14
Fengxu Li, Jiquan Zhang, Tiehua Cao, Sijia Li, Yanan Chen, Xuanhe Liang, Xin Zhao, Junwei Chen
The presence of toxic elements in agricultural soils from anthropogenic activities is a potential threat to human health through the food chain. In this study, the concentration of toxic elements in 122 agricultural topsoil composite samples were determined in order to study the current status, identify their sources and assess the level of pollution and human health risk. The results showed that the mean concentrations of Zn, Cu, Pb, Cd, Hg and As in the farmland topsoil were 21.72, 15.09, 36.08, 0.2451, 0...
May 22, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29788994/tick-abundance-pathogen-prevalence-and-disease-incidence-in-two-contrasting-regions-at-the-northern-distribution-range-of-europe
#15
Atle Mysterud, Vetle Malmer Stigum, Ingrid Vikingsdal Seland, Anders Herland, W Ryan Easterday, Solveig Jore, Olav Østerås, Hildegunn Viljugrein
BACKGROUND: Emergence of tick-borne diseases is impacting humans and livestock across the Northern Hemisphere. There are, however, large regional variations in number of cases of tick-borne diseases. Some areas have surprisingly few cases of disease compared to other regions. The aim here is to provide a first step towards a better understanding of such contrasting regional patterns of disease emergences at the northern distribution range of Ixodes ricinus in Europe. METHODS: We compare disease incidence, vector abundance and pathogen prevalence in eastern and western Norway differing in the number of tick-borne disease cases...
May 22, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29788924/exploration-of-the-association-between-foxe1-gene-polymorphism-and-differentiated-thyroid-cancer-a-meta-analysis
#16
Yong-Hui Chen, Ying-Qiang Zhang
BACKGROUND: Several association analyses and linkage researches indicated that inherited genetic variations effectively influence differentiated thyroid carcinogenesis. METHODS: The results from 15 published studies on differentiated thyroid carcinoma (DTC) were combined. The genetic model included rs965513, rs944289 and rs1867277. Meta-analyses were performed and cochran's χ2 based Q-statistic and I2 test were performed to assess heterogeneity using STATA software...
May 22, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29788691/a-novel-concept-for-determining-the-direction-of-implanted-hair-in-hairline-correction-surgery-in-east-asian-women
#17
Jae Hyun Park
No abstract text is available yet for this article.
May 2018: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29788464/confucian-values-as-a-buffer-against-age-based-stereotype-threat-for-chinese-older-adults
#18
Shyuan Ching Tan, Sarah J Barber
Objectives: Research has shown that stereotype threat can impair older adults' memory in Western cultures. We tested whether this also occurs for older adults from the East Asian Chinese culture. We also tested whether an intervention that highlighted Confucian principles would protect Chinese older adults from stereotype threat's detrimental effects. Method : Culturally-Chinese older adults residing in the United States completed a memory test either under age-based stereotype threat about cognitive decline or not...
May 16, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29788400/real-time-incidence-of-travel-related-symptoms-through-a-smartphone-based-app-remote-monitoring-system-a-pilot-study
#19
N Rodriguez-Valero, M J Ledesma Carbayo, D Cuadrado Sanchez, A Vladimirov, M Espriu, I Vera, M Roldan, T de Alba, S Sanz, J L Gonzalez Moreno, M Luengo Oroz, J Muñoz
Trip Doctor®, a Smartphone-based app monitoring system, was developed to detect infections among travelers in real-time. For testing, 106 participants were recruited (62.2% male, mean age 36 years (SD = 11)). Majority of trips were for tourism and main destinations were in South East Asia. Mean travel duration was 14 days (SD = 10). Diarrhea was the most frequently reported symptom (15.5%). The system demonstrated adequate usability and is ready to be used on a larger scale.
January 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29788280/genetic-and-environmental-factors-affecting-birth-size-variation-a-pooled-individual-based-analysis-of-secular-trends-and-global-geographical-differences-using-26-twin-cohorts
#20
Yoshie Yokoyama, Aline Jelenkovic, Yoon-Mi Hur, Reijo Sund, Corrado Fagnani, Maria A Stazi, Sonia Brescianini, Fuling Ji, Feng Ning, Zengchang Pang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Esther Rebato, John L Hopper, Tessa L Cutler, Kimberly J Saudino, Tracy L Nelson, Keith E Whitfield, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Clare H Llewellyn, Abigail Fisher, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Robert F Krueger, Matt McGue, Shandell Pahlen, Meike Bartels, Catharina E M van Beijsterveldt, Gonneke Willemsen, Jennifer R Harris, Ingunn Brandt, Thomas S Nilsen, Jeffrey M Craig, Richard Saffery, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Claire M A Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Finn Rasmussen, Per Tynelius, Adam D Tarnoki, David L Tarnoki, Syuichi Ooki, Richard J Rose, Kirsi H Pietiläinen, Thorkild I A Sørensen, Dorret I Boomsma, Jaakko Kaprio, Karri Silventoinen
Background: The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia) and across birth cohorts, and how gestational age modifies these effects. Methods: Data from 26 twin cohorts in 16 countries including 57 613 monozygotic and dizygotic twin pairs were pooled...
May 19, 2018: International Journal of Epidemiology
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