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https://www.readbyqxmd.com/read/27424071/executive-summary-of-the-guidelines-for-the-use-of-interferon-gamma-release-assays-in-the-diagnosis-of-tuberculosis-infection
#1
Miguel Santin, José-María García-García, David Rigau, Neus Altet, Luis Anibarro, Irma Casas, Nuria Díez, Mercedes García-Gasalla, Xavier Martínez-Lacasa, Antón Penas, Elvira Pérez-Escolano, Francisca Sánchez, José Domínguez
Interferon-gamma release assays are widely used for the diagnosis of tuberculosis infection in Spain. However, there is no consensus on their application in specific clinical scenarios. To develop a guide-line for their use, a panel of experts comprising specialists in infectious diseases, respiratory diseases, microbiology, pediatrics and preventive medicine, together with a methodologist, conducted a systematic literature search, summarized the findings, rated the quality of the evidence, and formulated recommendations following the Grading of Recommendations of Assessment Development and Evaluations methodology...
September 2016: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/25346992/-the-hrm-new-molecular-technique-of-detection-of-pharmaceutical-resistance-of-micobacteria-of-tuberculosis
#2
REVIEW
O I Lavrova, M V Al'vares Figerova, M G Tvorogova
The early detection of isolates of mycobacterium of tuberculosis resistant to anti-tuberculosis pharmaceuticals is ultimately needed for optimization of treatment scheme and prevention of propagation of resistant strains. The literature review presents analysis of data concerning the new, fast and inexpensive technique of detection of mutations in genes of mycobacterium of tuberculosis competent for multiple medicinal resistance. The molecular genetic technique HRM (high resolution melting curve analysis) is based on implementation of amplification of DNA fragments with subsequent analysis of their curves of melting with high resolution...
July 2014: Klinicheskaia Laboratornaia Diagnostika
https://www.readbyqxmd.com/read/23272392/-concurrent-interventions-for-pulmonary-tuberculosis-complicated-by-chronic-pleural-tuberculosis
#3
I D Duzhyĭ, N I Hlazunova, R Z El'-Astal', H P Piddubna
Basing on the literature data analysis the authors suppose the insufficient studying of issues, concerning simultant interventions for pulmonary tuberculosis, coinciding with chronic phthysic pleurytis. Surgical treatment of such processes was performed in 181 patients, total pleurectomy--in 172 (95%) of them, partial--in 9 (5%). Various kinds of pulmonary resection as the additional intervention were performed in 172 (95%) patients, extrapleural thoracoplasty--in 15 (8.3%), diaphragmatic plasty--in 15 (8.3%)...
November 2012: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/22686019/-ultrastructural-changes-in-cells-of-mycobacteria-affected-by-flurenizid-derivatives
#4
O R Kulachkovs'kyĭ, O Z Zarichna, A V Sybirnyĭ
In cells of micobacteria of all investigated samples the following ultrastructural changes were observed: disorganization of a nucleoid and citoplasm, formation of the citoplasmic vacuoles and endocellular lipide-like inclusions, and also change of the cells form into spheroid and formeless mass, disappearance of periplasmatic space, occurrence of cells of small-size and short incompletely divided cells in the samples. They were observed more often after 72 hours of exposition of the cultures with antibacterial substances, than after 24 hours of exposition...
March 2012: Mikrobiolohichnyĭ Zhurnal., Mikrobiologichny Zhurnal
https://www.readbyqxmd.com/read/22522153/-recommendations-from-the-spanish-society-of-paediatric-infectious-diseases-on-the-diagnosis-and-treatment-of-non-tuberculous-mycobacterial-cervical-lymphadenitis
#5
E Núñez Cuadros, F Baquero Artigao
Non-tuberculous mycobacteria (NTM) have been increasingly isolated over the last 20 years in Spain. However, as NTM disease is not a notifiable condition, there is no national registry, thus the true prevalence and incidence of these infections in children are difficult to estimate. Cervical adenitis is the most common clinical manifestation of NTM infection in immunocompetent children. The clinical course can be sub-acute or chronic, and is often associated with fluctuation, fistulisation, and scarring at a later stage...
September 2012: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/21496246/supramolecular-assemblies-of-rifampicin-and-cationic-bilayers-preparation-characterization-and-micobactericidal-activity
#6
Lilian Barbassa, Elsa M Mamizuka, Ana M Carmona-Ribeiro
BACKGROUND: Cationic bilayers based on the inexpensive synthetic lipid dioctadecyldimethylammonium bromide (DODAB) have been useful as carriers for drug delivery, immunoadjuvants for vaccines and active antimicrobial agents. METHODS: Rifampicin (RIF) or isoniazid (ISO) interacted with DODAB bilayer fragments (BF) or large vesicles (LV). Dispersions were evaluated by dynamic light-scattering for zeta-average diameter (Dz) and zeta-potential (ζ) analysis; dialysis for determination of drug entrapment efficiency; plating and CFU counting for determination of cell viability of Mycobacterium smegmatis or tuberculosis, minimal bactericidal concentration (MBC) and synergism index for DODAB/drug combinations...
2011: BMC Biotechnology
https://www.readbyqxmd.com/read/21234459/effect-of-preliminary-load-of-macrophages-with-silicium-dioxide-on-phagocytosis-of-bcg-strain-micobacteria-by-macrophages-and-antimicrobial-activity
#7
S A Arkhipov, V A Shkurupy, Yu S Bugrimova
We studied the effect of preliminary loading of peritoneal macrophages with silicium dioxide on in vitro viability, phagocytosis of BCG strain mycobacteria, and the capability to destroy the phagocytosed mycobacterium tuberculosis. It was shown that preliminary loading of macrophages with silicium dioxide did not reduce their viability and stimulated phagocytosis of BCG strain mycobacteria, but reduced their antibacterial activity.
October 2010: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/20469715/-1-st-young-scientist-s-competitions-endoscopic-diagnosis-of-esophageal-pathology-in-hiv-infected-patients-with-active-tuberculosis
#8
E I Trefil'eva
UNLABELLED: The main object of this work was to determine the role and place of esophagogastroduodenoscopy (EGDS) in the diagnostic diseases upper portion of the gastrointestinal tract. We analysed endoscopic pictures of patients, which have HIV and active form of tuberculosis (T. B.). THE MATERIALS AND METHODS: 141 patients with HIV/T. B., who are on the treatment in Tubercular hospital No 11 of Moscow, were examined during 2008 year. THE RESULTS: About 86% of patients (121 of 141) had a positive endoscopic picture of gastroesophageal reflux disease (GERB)...
2009: Experimental & Clinical Gastroenterology
https://www.readbyqxmd.com/read/20209361/-differentiation-of-micobacteria-by-multiplex-pcr
#9
Diogo da Rocha Poroca, Andrea Santos Lima, Juliana Falcão de Araújo Lima, Heidi Lacerda Alves da Cruz, Rosana de Albuquerque Montenegro, Fábio Lopes de Melo, Haiana Charifker Schindler, Lílian Maria Lapa Montenegro
This study aimed to optimize a method based on the polymerase chain reaction - multiplex PCR - for differentiation of mycobacteria species of interest for public health. The multiplex PCR was based on simultaneous amplification of the hsp65 gene, which is present in all species of the Mycobacterium genus, the dnaJ gene, which is present only in Mycobacterium tuberculosis and Mycobacterium avium and the IS6110 insertion sequence, which is present in the Mycobacterium tuberculosis complex, generating amplicons of 165 bp, 365 bp and 541 bp, respectively...
November 2009: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/17899696/cnk-t-cell-brain-lymphoma-associated-with-epstein-barr-virus-in-a-patient-with-aids
#10
Fernando Cobo, Paloma Talavera, Heriberto Busquier, Angel Concha
We report a case of extranodal NK/T-cell lymphoma, nasal type, with exclusive cerebral localization in a patient with AIDS. The patient presented with neurological alterations, fever and convulsions, so the initial presumptive diagnosis was an opportunistic brain infection. MRI showed a left parietal necrotic lesion and a stereotactic brain biopsy was performed for pathological, microbiological and molecular studies. Histological sections showed an angiocentric and angiodestructive growth pattern and the immunophenotype of this tumor was CD56+, CD45+, CD3+ (cytoplasmic), Granzyme B+ and Perforin+...
August 2007: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/16178466/-mycobacterium-bovis-tuberculosis-in-a-female-patient-with-aids
#11
M Valerga, C Viola, A Thwaites, O Bases, M Ambroggi, S Poggi, R Marino
M. bovis, the agent of bovine tuberculosis, was in other times, the main ethiological agent of tuberculosis (TBC) in industrialized countries. At the moment, the human cases have become not very frequent, except in those countries where the illness is even endemic. In patients with immunodeficiency syndrome, it usually presents as a systemic illness. We present the case of a woman with AIDS and disseminated TBC caused by M. bovis. The isolated micobacteria turned out to be resistant to rifampin and pyrazinamide...
April 2005: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/13051376/-the-enzymology-of-micobacteria-and-their-significance-for-the-analysis-of-the-effect-of-various-antibiotics
#12
E A ZELLER
No abstract text is available yet for this article.
1953: Beiträge Zur Klinik der Tuberkulose und Spezifischen Tuberkulose-Forschung
https://www.readbyqxmd.com/read/10918089/-current-state-of-multidrug-resistance-in-tuberculosis
#13
COMPARATIVE STUDY
M Casal, J Gutiérrez, P Ruiz
Given the current concern about multiresistance to drugs in tuberculosis, the data from a large study in two different centers are presented. At the Hospital Universitario Reina Sofía de Córdoba 71,359 clinical isolates of Mycobacterium tuberculosis were processed and at the Centro de Referencia de Micobacterias 2,350 cultures were studied. The percentage of total multiresistance at the Hospital Universitario was 6% from 1996-1998, and 6.7% at the Centro de Referencia in 1998. Although these figures are high, they are lower than in previous years and could indicate the beginning of a decreasing trend, following years of increasing in the 1990s...
June 2000: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/10547911/-tuberculosis-resistant-to-treatment-with-antitubercular-drugs-a-study-in-the-state-of-chiapas-mexico
#14
G C Alvarez Gordillo, H Sandoval Trujillo, L F Bojalil Jaber
OBJECTIVE: To identify the frequency of drug resistant tuberculosis and to determine risk factors for its development in five health districts in the State of Chiapas, Mexico. DESIGN: A cross-sectional study. EMPLACEMENT: Primary care. PARTICIPANTS: Patients with pulmonary tuberculosis diagnosed between September 1 and December 31, 1995. Each patient responded to a questionnaire regarding epidemiological, diagnostic and treatment variables...
September 15, 1999: Atencion Primaria
https://www.readbyqxmd.com/read/9780553/-ultrastructural-aspects-of-lesions-caused-by-mycobacterium-spp-in-aids
#15
D Parada, E Caleiras, S Estrada, R Tovar, J García-Tamayo
Samples from necrotizing lesions in eight autopsy cases of AIDS were examined with transmission electron microscopy. They were selected among 35 autopsies of Mycobacterium spp infection and AIDS, and were part of a series of 230 autopsy cases of AIDS performed from 1984 to 1995 in the Anatomopathologic Institute at Central University of Venezuela. Ultrastructural aspects of micobacteriae, their relationship with macrophages and tissue alterations are discussed and related to the immune defcit observed in AIDS patients...
September 1998: Investigación Clínica
https://www.readbyqxmd.com/read/4473598/-symposium-2-effects-of-chemical-structure-and-biological-activity-of-peptidoglycolipid-on-the-pattern-of-action-of-the-micobacteria-derived-adjuvant
#16
D E Stewart-Tull
No abstract text is available yet for this article.
June 1974: Nihon Rinsho. Japanese Journal of Clinical Medicine
https://www.readbyqxmd.com/read/1144289/-atypical-mycobacterias-in-mexico-incidence-and-epidemiology-in-a-general-hospital
#17
A C Frati Munari, R Vargas Cuba, L Vergara Sedeño, S Gonzaĺez Sanchez
All the cultures for mycobacteriae taken from 1967 to 1973 at the Hospital General del Centro Médico Nacional del Instituto Mexicano del Seguro Social were reviewed. From 802 positive cultures, 361 (44.2 per cent) were atypical mycobacteriae. 89 per cent of them were scotochromogen, 10.3 per cent of rapid growth, one non-chromogen, and none were photochromogen. These data are in contrast with those observed in other countries. Isolation sources varied also from other reports, in this series the most common isolation were from urine specimens, sputum, feces and bone marrow...
January 1975: La Prensa Médica Mexicana
https://www.readbyqxmd.com/read/177028/analysis-of-metabolic-changes-in-revertants-of-antibiotic-resistant-micobacteria
#18
M Alberghina, F Palermo
In the present report evaluation of the possible metabolic changes in partially revertants of M. tuberculosis var. hominis, reisolated from strains at high levels of drug-resistance after treatment with mutagenic agents, was reported. Based on the data presented here, it must be concluded that no significant biological and biochemical differences in mycobacterial cells revertant from high mutants mono-resistant to four aminoglycosides (Sm, Kana, Vio, Neo) and p-aminonasalicylic acid (PAS) are to be found.
1975: Bollettino Dell'Istituto Sieroterapico Milanese
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