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https://www.readbyqxmd.com/read/28445888/differential-effects-of-inflammatory-and-psychosocial-stress-on-mood-hypothalamic-pituitary-adrenal-axis-and-inflammation-in-remitted-depression
#1
Peter Niemegeers, Peter De Boer, Glenn J H Dumont, Filip Van Den Eede, Erik Fransen, Stephan J Claes, Manuel Morrens, Bernard G C Sabbe
BACKGROUND/AIMS: Major depressive disorder (MDD) is highly recurrent. This may be due to increased stress sensitivity after remission. Both inflammatory and psychosocial stressors are implicated in the pathogenesis of MDD, but the additive or differential effect is unclear. METHODS: We conducted a single-blind placebo-controlled study to investigate the effects of inflammatory stress (i.e., typhoid vaccination), psychosocial stress (i.e., Trier Social Stress Test [TSST]), or a combination of both in women (25-45 years old) with (partially) remitted recurrent MDD (n = 21) and healthy female controls (n = 18)...
April 27, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28445727/environmental-enrichment-induces-pericyte-and-iga-dependent-wound-repair-and-lifespan-extension-in-a-colon-tumor-model
#2
Benjamin D Bice, Megan R Stephens, Stephanie J Georges, Ashlee R Venancio, Peter C Bermant, Annika V Warncke, Kajsa E Affolter, Julio R Hidalgo, Melinda L Angus-Hill
Environmental enrichment (EE) replicates mind-body therapy by providing complex housing to laboratory animals to improve their activity levels, behavior, and social interactions. Using a Tcf4(Het/+)Apc(Min/+)-mediated model of colon tumorigenesis, we found that EE vastly improved the survival of tumor-bearing animals, with differential effect on tumor load in male compared to female animals. Analysis of Tcf4(Het/+)Apc(Min/+) males showed drastically reduced expression of circulating inflammatory cytokines and induced nuclear hormone receptor (NHR) signaling, both of which are common in the wound repair process...
April 25, 2017: Cell Reports
https://www.readbyqxmd.com/read/28445214/teaching-the-social-determinants-of-health-a-path-to-equity-or-a-road-to-nowhere
#3
Malika Sharma, Andrew D Pinto, Arno K Kumagai
Medical schools are increasingly called to include social responsibility in their mandates. As such, they are focusing their attention on the social determinants of health (SDOH) as key drivers in the health of the patients and communities they serve. However, underlying this emphasis on SDOH is the assumption that teaching medical students about SDOH will lead future physicians to take action to help achieve health equity. There is little evidence to support this belief. In many ways, the current approach to SDOH within medical education positions the SDOH as "facts to be known" rather than as "conditions to be challenged and changed...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28444554/relationships-between-environmental-factors-and-participation-in-adults-with-traumatic-brain-injury-stroke-and-spinal-cord-injury-a-cross-sectional-multi-center-study
#4
Alex W K Wong, Sheryl Ng, Jessica Dashner, M Carolyn Baum, Joy Hammel, Susan Magasi, Jin-Shei Lai, Noelle E Carlozzi, David S Tulsky, Ana Miskovic, Arielle Goldsmith, Allen W Heinemann
PURPOSE: To develop and evaluate a model of environmental factors-participation relationships for persons with traumatic brain injury (TBI), stroke, and spinal cord injury (SCI), and test whether this model differed across three diagnostic groups, as well as other demographic and clinical characteristics. METHODS: A cross-sectional observational study included 545 community-dwelling adults with neurological disorders (TBI = 166; stroke = 189; SCI = 190) recruited at three academic medical centers...
April 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28444208/adverse-impacts-of-chronic-pain-on-health-related-quality-of-life-work-productivity-depression-and-anxiety-in-a-community-based-study
#5
Kosuke Kawai, Alison Tse Kawai, Peter Wollan, Barbara P Yawn
Background.: Chronic pain has major clinical and social consequences. Few studies have examined any variation in the extent of impairment on quality of life and work productivity by site and type of chronic pain. Objective.: The objective of our study is to examine adverse impacts of chronic pain on physical and psychological health and work productivity. Methods.: Our community-population study was based on a phone-interview of adults with chronic pain, residing in Olmsted County, MN...
April 22, 2017: Family Practice
https://www.readbyqxmd.com/read/28443992/educational-interventions-for-knowledge-on-the-disease-treatment-adherence-and-control-of-diabetes-mellitus
#6
Ana Laura Galhardo Figueira, Lilian Cristiane Gomes Villas Boas, Anna Claudia Martins Coelho, Maria Cristina Foss de Freitas, Ana Emilia Pace
OBJECTIVE: to assess the effect of educational interventions for knowledge on the disease, medication treatment adherence and glycemic control of diabetes mellitus patients. METHOD: evaluation research with "before and after" design, developed in a sample of 82 type 2 diabetes mellitus patients. To collect the data, the Brazilian version of the Diabetes Knowledge Scale (DKN-A), the Measure of Adherence to Treatments and the electronic system at the place of study were used...
April 20, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28443981/mapping-the-dengue-scientific-landscape-worldwide-a-bibliometric-and-network-analysis
#7
Fabio Batista Mota, Bruna de Paula Fonseca E Fonseca, Andréia Cristina Galina, Roseli Monteiro da Silva
BACKGROUND: Despite the current global trend of reduction in the morbidity and mortality of neglected diseases, dengue's incidence has increased and occurrence areas have expanded. Dengue also persists as a scientific and technological challenge since there is no effective treatment, vaccine, vector control or public health intervention. Combining bibliometrics and social network analysis methods can support the mapping of dengue research and development (R&D) activities worldwide. OBJECTIVES: The aim of this paper is to map the scientific scenario related to dengue research worldwide...
May 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28443678/outcomes-along-the-hiv-care-continuum-among-undocumented-immigrants-in-clinical-care
#8
Jonathan Ross, Uriel R Felsen, Chinazo O Cunningham, Viraj V Patel, David B Hanna
HIV-infected undocumented immigrants face unique barriers to care yet little is known about their clinical outcomes. We performed a retrospective cohort study of HIV-infected adults in clinical care from 2006-2014 at a large academic medical center in a setting where medical insurance is available to HIV-infected undocumented immigrants. Undocumented status was assessed based on Social Security number and insurance status and verified through medical chart review. Using Poisson regression models, we compared undocumented and documented patients with respect to retention in care (≥ 2 HIV-related lab tests ≥ 90 days apart), antiretroviral therapy (ART) prescription (≥ 3 active antiretroviral agents prescribed in a year) and viral suppression (HIV RNA <200 copies/ml for the last measured viral load) for each year in care...
April 26, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28443647/identifying-and-modeling-the-structural-discontinuities-of-human-interactions
#9
Sebastian Grauwin, Michael Szell, Stanislav Sobolevsky, Philipp Hövel, Filippo Simini, Maarten Vanhoof, Zbigniew Smoreda, Albert-László Barabási, Carlo Ratti
The idea of a hierarchical spatial organization of society lies at the core of seminal theories in human geography that have strongly influenced our understanding of social organization. Along the same line, the recent availability of large-scale human mobility and communication data has offered novel quantitative insights hinting at a strong geographical confinement of human interactions within neighboring regions, extending to local levels within countries. However, models of human interaction largely ignore this effect...
April 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28443367/preventing-risky-behaviours-among-young-adolescents-in-eastern-democratic-republic-of-congo-a-qualitative-study
#10
Anjalee Kohli, Mitima Mpanano Remy, Arsene Kajabika Binkurhorhwa, Clovis Murhula Mitima, Alfred Bacikenge Mirindi, Nadine Bufole Mwinja, Jean Heri Banyewesize, Gisele Mushengezi Ntakwinja, Nancy A Perrin, Nancy Glass
This qualitative study explores and describes adolescent risk behaviours, specifically consumption of alcohol and use of violence; the perceived consequences of these behaviours on future well-being and relationships; and collaboratively identifies the essential components of a prevention intervention for risk behaviours (alcohol use, violence) among young adolescents while strengthening the protective individual and relationship factors in post-conflict Democratic Republic of Congo. One-on-one in-depth interviews were conducted with 28 male and female youth, 20 parents/guardians and 20 stakeholders in three rural villages of South Kivu Province...
April 26, 2017: Global Public Health
https://www.readbyqxmd.com/read/28443220/do-factors-associated-self-rated-good-health-and-their-influences-differ-between-males-and-females-across-different-age-groups-in-korean-and-australia
#11
Hyo Young Lee, Stephanie Doris Short
OBJECTIVES: This was a comparative study between Australia and Korea that investigated whether and to what extent factors related to self-rated good health (SRGH) differ by gender among age groups. METHODS: This study was a secondary analysis of data that were collected in nationally representative, cross-sectional, and population-based surveys. We analyzed Australian and Korean participants > 20 years of age using 2011 data from the Australian National Nutritional Physical Activity Survey (n = 9,276) and the Korean National Health and Nutritional Examination Survey (n = 5,915)...
February 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/28443041/national-identification-counteracts-the-sedative-effect-of-positive-intergroup-contact-on-ethnic-activism
#12
Adrienne Pereira, Eva G T Green, Emilio Paolo Visintin
Positive intergroup contact with socially and economically advantaged national majorities has been shown to reduce ethnic identification among minorities, thereby undermining ethnic minority activism. This finding implies that ethnic identity is the relevant social identity driving ethnic minorities' struggle for equality. We argue that the study of the "sedating" effect of positive intergroup contact for minorities should be more nuanced. The existence of multiple and sometimes interplaying social identities can foster a reinterpretation of the meaning of "ethnic" activism...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28442902/self-rated-health-aspects-among-persons-living-with-chronic-obstructive-pulmonary-disease
#13
Anne-Grethe Halding, Ellen Karine Grov
PURPOSE: To describe a cohort of chronic obstructive pulmonary disease (COPD) patients and perform a within-group comparison regarding self-management activation, social provision, and health status. PATIENTS AND METHODS: A cross-sectional survey including 116 persons. RESULTS: The sample comprised 65 men and 38 women, mean age 69 years. Fourteen percent reported very high impact of COPD on their health; 19% had received pulmonary rehabilitation offers, 39% had been offered self-management education, and 64% had acute hospital admissions due to COPD complications in the past year...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28442744/biomimetic-antimicrobial-cloak-by-graphene-oxide-agar-hydrogel
#14
Massimiliano Papi, Valentina Palmieri, Francesca Bugli, Marco De Spirito, Maurizio Sanguinetti, Carlotta Ciancico, Maria Chiara Braidotti, Silvia Gentilini, Luca Angelani, Claudio Conti
Antibacterial surfaces have an enormous economic and social impact on the worldwide technological fight against diseases. However, bacteria develop resistance and coatings are often not uniform and not stable in time. The challenge is finding an antibacterial coating that is biocompatible, cost-effective, not toxic, and spreadable over large and irregular surfaces. Here we demonstrate an antibacterial cloak by laser printing of graphene oxide hydrogels mimicking the Cancer Pagurus carapace. We observe up to 90% reduction of bacteria cells...
December 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28442452/homestyles-a-web-based-childhood-obesity-prevention-program-for-families-with-preschool-children-protocol-for-a-randomized-controlled-trial
#15
Carol Byrd-Bredbenner, Jennifer Martin-Biggers, Mallory Koenings, Virginia Quick, Nobuko Hongu, John Worobey
BACKGROUND: The home environment is where young children spend most of their time, and is critically important to supporting behaviors that promote health and prevent obesity. However, the home environment and lifestyle patterns remain understudied, and few interventions have investigated parent-led makeovers designed to create home environments that are supportive of optimal child health and healthy child weights. OBJECTIVE: The aim of the HomeStyles randomized controlled trial (RCT) is to determine whether the Web-based HomeStyles intervention enables and motivates parents to shape the weight-related aspects of their home environments and lifestyle behavioral practices (diet, exercise, and sleep) to be more supportive of their preschool children's optimal health and weight...
April 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28442360/the-oxtr-gene-implicit-learning-and-social-processing-does-empathy-evolve-from-perceptual-skills-for-details
#16
Martin Melchers, Christian Montag, Sebastian Markett, Nawael Niazy, Johanna Groß-Bölting, Jelena Zimmermann, Martin Reuter
Oxytocin is an important messenger in the brain that has been linked to a variety of social functions in pharmacological studies. Besides, functional genetic variations on the oxytocin receptor gene have been repeatedly associated with social processing and functioning. Despite this knowledge, there are very few studies investigating the mechanisms that may explain the link between oxytocin and social functions. In the endeavor to fill this gap in the literature, the current study searches for associations between the prominent rs2268498 polymorphism on the oxytocin receptor gene and participants' ability to perceive and store implicit social information, which is a fundamental function in social information processing...
April 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28442353/facebook-usage-on-smartphones-and-gray-matter-volume-of-the-nucleus-accumbens
#17
Christian Montag, Alexander Markowetz, Konrad Blaszkiewicz, Ionut Andone, Bernd Lachmann, Rayna Sariyska, Boris Trendafilov, Mark Eibes, Julia Kolb, Martin Reuter, Bernd Weber, Sebastian Markett
A recent study has implicated the nucleus accumbens of the ventral striatum in explaining why online-users spend time on the social network platform Facebook. Here, higher activity of the nucleus accumbens was associated with gaining reputation on social media. In the present study, we touched a related research field. We recorded the actual Facebook usage of N=62 participants on their smartphones over the course of five weeks and correlated summary measures of Facebook use with gray matter volume of the nucleus accumbens...
April 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28442175/reframing-continence-care-in-care-dependence
#18
Joan Ostaszkiewicz
International guidelines promote active investigation and treatment of incontinence; however, these guidelines do not fully accommodate the psychosocial aspects associated with providing continence care i.e. the caregiving dynamics. The author developed a new framework that aims to support nurses and care workers in their efforts to identify and meet the continence care needs of individuals with complex health conditions who are dependent on another person for assistance to manage incontinence or to maintain continence...
April 23, 2017: Geriatric Nursing
https://www.readbyqxmd.com/read/28442074/predictors-of-perceived-barriers-to-physical-activity-in-the-general-adult-population-a-cross-sectional-study
#19
Yaneth Herazo-Beltrán, Yisel Pinillos, José Vidarte, Estela Crissien, Damaris Suarez, Rafael García
BACKGROUND: The perception of personal barriers to physical activity varies according to the sociodemographic characteristics of individuals. OBJECTIVE: To determine the predictors of the perception of barriers to physical activity in the adult population. METHOD: A cross-sectional study with 1066 adult women and 1036 adult men. The sociodemographic variables (age, gender, marital status, socioeconomic level, level of education), the perception of barriers that do not allow performance of physical activity (i...
January 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28441895/ketamine-s-dose-related-effects-on-anxiety-symptoms-in-patients-with-treatment-refractory-anxiety-disorders
#20
Paul Glue, Natalie J Medlicott, Sarah Harland, Shona Neehoff, Bridie Anderson-Fahey, Martin Le Nedelec, Andrew Gray, Neil McNaughton
The N-methyl-D-aspartate receptor antagonist ketamine has rapid onset activity in treatment-resistant depression, post-traumatic stress disorder and obsessive compulsive disorder. Due to similarities in brain network activity in depression and anxiety disorders, we hypothesized that ketamine might also be active in other refractory anxiety disorders. We evaluated the efficacy and safety of ketamine in 12 patients with refractory generalized anxiety disorder and/or social anxiety disorder who were not currently depressed, using an ascending single dose study design (0...
April 1, 2017: Journal of Psychopharmacology
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