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https://www.readbyqxmd.com/read/28093301/protocol-driven-management-of-suspected-common-duct-stones
#1
Anthony Manning, Richard Frazee, Stephen Abernathy, Claire Isbell, Travis Isbell, Justin Regner, Yolanda Munoz Maldanado, Randall Smith
INTRO: Common duct stones can be diagnosed by magnetic resonance cholangiopancreatography (MRCP), endoscopic ultrasound/endoscopic retrograde cholangiopancreatography (EUS/ERCP), and intra-operative cholangiogram (IOC). In 2015, our group adopted a standard approach of preoperative EUS/ERCP followed by laparoscopic cholecystectomy for patients with an admission bilirubin over 4.0 (mg/dL). For bilirubin less than 4.0, laparoscopic cholecystectomy with IOC was the initial procedure. Post-operative EUS/ERCP with endoscopic sphincterotomy was pursued for positive IOC...
January 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28029219/defining-the-tipping-point-in-surgical-performance-for-laparoscopic-donor-nephrectomy-among-transplant-surgery-fellows-a-risk-adjusted-cumulative-summation-learning-curve-analysis
#2
O K Serrano, A S Bangdiwala, D M Vock, D Berglund, T B Dunn, E B Finger, T L Pruett, A J Matas, R Kandaswamy
UNOS recommends that fellowship-trained surgeons participate in 15 LDN to be considered proficient. ASTS mandates 12 LDN during abdominal transplant surgery fellowship (ATSF). We performed a retrospective intraoperative case analysis to create a risk-adjusted cumulative summation (RACUSUM) model to assess the learning curve (LC) of novice TSF (nTSF). Between January 2000 and December 2014, 30 nTSF rotated on the Organ Procurement Rotation (OPR) of our ASTS-approved ATSF. Measures of surgical performance included: 1) intraoperative time (ORT), 2) estimated blood loss (EBL), and 3) incidence of intraoperative complications (IOC)...
December 28, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/28028405/complications-of-laparoscopic-cholecystectomy-our-experience-from-a-retrospective-analysis
#3
Miodrag Radunovic, Ranko Lazovic, Natasa Popovic, Milorad Magdelinic, Milutin Bulajic, Lenka Radunovic, Marko Vukovic, Miroslav Radunovic
AIM: The aim of this study was to evaluate the intraoperative and postoperative complications of laparoscopic cholecystectomy, as well as the frequency of conversions. MATERIAL AND METHODS: Medical records of 740 patients who had laparoscopic cholecystectomy were analysed retrospectively. We evaluated patients for the presence of potential risk factors that could predict the development of complications such as age, gender, body mass index, white blood cell count and C-reactive protein (CRP), gallbladder ultrasonographic findings, and pathohistological analysis of removed gallbladders...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27992066/assessing-the-bioaccumulation-potential-of-ionizable-organic-compounds-current-knowledge-and-research-priorities
#4
REVIEW
James M Armitage, Russell J Erickson, Till Luckenbach, Carla A Ng, Ryan S Prosser, Jon A Arnot, Kristin Schirmer, John W Nichols
The objective of the present study was to review the current knowledge regarding the bioaccumulation potential of ionizable organic compounds (IOCs), with a focus on the availability of empirical data for fish. Aspects of the bioaccumulation potential of IOCs in fish that can be characterized relatively well include the pH dependence of gill uptake and elimination, uptake in the gut, and sorption to phospholipids (membrane-water partitioning). Key challenges include the lack of empirical data for biotransformation and binding in plasma...
November 7, 2016: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/27986260/utility-of-mrcp-in-clinical-decision-making-of-suspected-choledocholithiasis-an-institutional-analysis-and-literature-review
#5
Wesley R Badger, Andrew J Borgert, Kara J Kallies, Shanu N Kothari
BACKGROUND: The ideal treatment algorithm for suspected choledocholithiasis is not yet well defined. Imaging options include magnetic resonance cholangiopancreatography (MRCP), endoscopic retrograde cholangiopancreatography (ERCP), and intraoperative cholangiogram (IOC). MRCP is diagnostic, while the other two modalities can also be therapeutic. Each of these modalities for diagnosis and treatment carries its own set of risks, benefits, and institutional costs. We hypothesized that there would be a significant difference between the biochemical profiles and characteristics of patients who undergo ERCP vs...
December 1, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27934284/which-molecular-features-affect-the-intrinsic-hepatic-clearance-rate-of-ionizable-organic-chemicals-in-fish
#6
Yi Chen, Joop L M Hermens, Michiel T O Jonker, Jon A Arnot, James M Armitage, Trevor Brown, John W Nichols, Kellie A Fay, Steven T J Droge
Greater knowledge of biotransformation rates for ionizable organic compounds (IOCs) in fish is required to properly assess the bioaccumulation potential of many environmentally relevant contaminants. In this study, we measured in vitro hepatic clearance rates for 50 IOCs using a pooled batch of liver S9 fractions isolated from rainbow trout (Oncorhynchus mykiss). The IOCs included four types of strongly ionized acids (carboxylates, phenolates, sulfonates, and sulfates), three types of strongly ionized bases (primary, secondary, tertiary amines), and a pair of quaternary ammonium compounds (QACs)...
December 6, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27933720/autogenous-bone-grafting-for-treatment-of-osseous-defect-after-impacted-mandibular-third-molar-extraction-a-randomized-controlled-trial
#7
Jing Ge, Chi Yang, Jiawei Zheng, Yingkai Hu
BACKGROUND: Extraction of impacted mandibular third molar (M3) has been cited as causing osseous defect at the distal aspect of the adjacent second molar (M2). PURPOSE: This randomized controlled trial was aimed to evaluate the effect of autogenous bone grafting in situ for regeneration of periodontal osseous defect distal to the M2 compared with non-grafting after impacted M3 removal. MATERIALS AND METHODS: A total of 60 sites in 51 adult patients were enrolled and randomly assigned to the control group or the test group...
December 8, 2016: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/27912114/remediation-of-cr-vi-by-inorganic-organic-clay
#8
Suramya I Rathnayake, Wayde N Martens, Yunfei Xi, Ray L Frost, Godwin A Ayoko
Application of inorganic-organic clays (IOCs) for the remediation of hexavalent chromium (Cr (VI)) and the effect of bisphenol-A (BPA) were investigated. IOCs were better adsorbents for the removal of Cr (VI) than organoclay. Solution pH significantly affected the surface charge of IOCs and speciation of Cr in the solution; hence, the adsorption of Cr onto IOCs. Pseudo-second order model and Langmuir model were the best fit for the kinetics and equilibrium data, indicating chemisorption and formation of monolayer on homogenous adsorption sites, respectively...
March 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/27900197/research-priorities-of-international-sporting-federations-and-the-ioc-research-centres
#9
Caroline F Finch, Scott Talpey, Ashley Bradshaw, Torbjorn Soligard, Lars Engebretsen
BACKGROUND/AIM: To be fully effective, the prevention of injury in sport and promotion of athlete's health needs to be both targeted and underpinned by scientific evidence. This study aimed to identify the research priorities of International Sporting Federation (ISFs) compared to the current research focus of the International Olympic Committee Research Centres (IOC-RCs). METHODS: Online survey of ISF Medical Chairpersons (n=22, 69% response) and IOC-RC Directors (n=7, 78% response)...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27879256/determination-and-regulation-of-body-composition-in-elite-athletes
#10
Peter Sonksen
In 2011, the International Association of Athletics Federations (IAAF) and IOC introduced a 'hyperandrogenism' rule that excluded women with a serum testosterone >10 nmol/L from participating in elite sport. This rule was based on the false premise that the greater lean body mass in men was a consequence of their higher serum testosterone. This rule did not have scientific backing and the Court of Arbitration for Sport subsequently rescinded the rule following an appeal from an Indian athlete barred from the Commonwealth Games...
November 22, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27863870/fast-and-slow-adsorption-of-carbamazepine-on-biochar-as-affected-by-carbon-structure-and-mineral-composition
#11
Jian Chen, Di Zhang, Huang Zhang, Saikat Ghosh, Bo Pan
The influence of carbon structure and mineral composition of biochar on fast adsorption and slow adsorption of ionic organic contaminants (IOCs) is still unclear. This study used carbamazepine (CBZ) as adsorbate, peanut-shell-derived biochars produced at different charred temperatures, and the corresponding acid-washed biochars as adsorbents, to investigate the adsorption kinetics as affected by carbon structure and mineral composition of biochar. The adsorption of CBZ on amorphous (loose) carbon was lower than aromatic (condensed) carbon, but the former mainly contributed to the fast adsorption of CBZ...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27862627/perceived-impact-of-cancer-among-adolescents-and-young-adults-relationship-with-health-related-quality-of-life-and-distress
#12
O Husson, B Zebrack
OBJECTIVE: To examine whether perceptions of the impact of cancer are related to health-related quality of life (HRQoL) and psychological distress among survivors of cancer in adolescence and young adulthood (AYA). METHODS: 173 AYA cancer survivors (aged 18-35 years and 15-29 years at time of diagnosis) completed a mailed survey assessing impact of cancer (IOC-AYA), HRQoL (SF-36), and distress (BSI-18). Hierarchical linear regression models analyzed the independent effects of perceived impacts of cancer on HRQoL and distress after controlling for clinical and socio-demographic characteristics...
November 8, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27857966/endoscopic-versus-laparoscopic-treatment-for-choledocholithiasis-a-prospective-randomized-controlled-trial
#13
Javier Ernesto Barreras González, Rafael Torres Peña, Julián Ruiz Torres, Miguel Ángel Martínez Alfonso, Raúl Brizuela Quintanilla, Maricela Morera Pérez
Background and study aims: Overall, 5 % to 15 % of patients undergoing cholecystectomy for cholelithiasis have concomitant bile duct stones, and the incidence of choledocholithiasis increases with age. There is no clear consensus on the best therapeutic approach (endoscopic versus surgical). Patients and methods: A prospective randomized controlled clinical trial was performed to compare three treatment options for patients with choledocholithiasis at the National Center for Minimally Invasive Surgery in Havana, Cuba from November 2007 to November 2011...
November 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27844236/biliary-tract-visualization-using-near-infrared-imaging-with-indocyanine-green-during-laparoscopic-cholecystectomy-results-of-a-systematic-review
#14
S L Vlek, D A van Dam, S M Rubinstein, E S M de Lange-de Klerk, L J Schoonmade, J B Tuynman, W J H J Meijerink, M Ankersmit
BACKGROUND: Near-infrared imaging with indocyanine green (ICG) has been extensively investigated during laparoscopic cholecystectomy (LC). However, methods vary between studies, especially regarding patient selection, dosage and timing. The aim of this systematic review was to evaluate the potential of the near-infrared imaging technique with ICG to identify biliary structures during LC. METHODS: A comprehensive systematic literature search was performed. Prospective trials examining the use of ICG during LC were included...
November 14, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27826873/comparison-of-the-impact-of-cancer-between-british-and-us-long-term-non-hodgkin-lymphoma-survivors
#15
Shah-Jalal Sarker, Sophia K Smith, Kashfia Chowdhury, Patricia A Ganz, Sheryl Zimmerman, John Gribben, Ania Korszun
PURPOSE: The aims of this study were to examine quality of life, using the Impact of Cancer version 2 (IOCv2), in British non-Hodgkin lymphoma (NHL) survivors and investigate differences between survivors in the UK and the USA. METHODS: NHL survivors (326 UK and 667 US) completed the 37-item IOCv2 and psychological distress, fatigue and social support questionnaires. RESULTS: The IOCv2 showed good reliability in the British sample with higher internal consistency (Cronbach alpha 0...
November 8, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27780559/routine-intraoperative-cholangiography-is-unnecessary-in-patients-with-mild-gallstone-pancreatitis-and-normalizing-bilirubin-levels
#16
Xuan-Binh D Pham, Christian de Virgilio, Lutfi Al-Khouja, Michael C Bermudez, Alexander C Schwed, Amy H Kaji, David S Plurad, Steven L Lee, Robert S Bennion, Darin J Saltzman, Dennis Y Kim
BACKGROUND: The benefit of intraoperative cholangiography (IOC) is controversial in patients with gallstone pancreatitis whose bilirubin levels are normalizing. IOC with subsequent endoscopic retrograde cholangiopancreatography may lengthen duration of surgery and length of stay, whereas failure to clear the common bile duct may result in recurrent pancreatitis. METHODS: We performed a 6-year retrospective cohort analysis of consecutive adult patients with mild gallstone pancreatitis undergoing same-admission cholecystectomy at 2 university-affiliated medical centers...
December 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27779989/analysis-of-endoscopic-retrograde-cholangiopancreatography-after-positive-intraoperative-cholangiogram-is-it-necessary
#17
John V Gahagan, Steven Maximus, Matthew D Whealon, Michael J Phelan, Aram Demirjian, Victor C Joe
The necessity of routine endoscopic retrograde cholangiopancreatography (ERCP) after positive intraoperative cholangiogram (IOC) during laparoscopic cholecystectomy is not well defined. We aimed to examine the incidence of positive IOC among patients who undergo IOC during cholecystectomy and the rate of subsequent ERCP stone extraction. The Nationwide Inpatient Sample database was reviewed for all patients undergoing cholecystectomy with IOC from 2002 to 2012. Patients were then analyzed for ERCP and stone extraction...
October 2016: American Surgeon
https://www.readbyqxmd.com/read/27761885/diagnostic-assessment-of-intraoperative-cytology-for-papillary-thyroid-carcinoma-using-a-decision-tree-analysis
#18
J-S Pyo, J H Sohn, G Kang
PURPOSE: The aim of this study was to elucidate the cytological characteristics and the diagnostic usefulness of intraoperative cytology (IOC) for papillary thyroid carcinoma (PTC). In addition, using decision tree analysis, effective features for accurate cytological diagnosis were sought. METHODS: We investigated cellularity, cytological features and diagnosis based on the Bethesda System for Reporting Thyroid Cytopathology in IOC of 240 conventional PTCs. The cytological features were evaluated in terms of nuclear score with nuclear features, and additional figures such as presence of swirling sheets, psammoma bodies, and multinucleated giant cells...
October 19, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27733352/exercise-and-pregnancy-in-recreational-and-elite-athletes-2016-evidence-summary-from-the-ioc-expert-group-meeting-lausanne-part-2-the-effect-of-exercise-on-the-fetus-labour-and-birth
#19
Kari Bø, Raul Artal, Ruben Barakat, Wendy Brown, Michael Dooley, Kelly R Evenson, Lene A H Haakstad, Karin Larsen, Bengt Kayser, Tarja I Kinnunen, Michelle F Mottola, Ingrid Nygaard, Mireille van Poppel, Britt Stuge, Gregory A L Davies
This is Part 2 of 5 in the series of evidence statements from the IOC expert committee on exercise and pregnancy in recreational and elite athletes. Part 1 focused on the effects of training during pregnancy and on the management of common pregnancy-related symptoms experienced by athletes. In Part 2, we focus on maternal and fetal perinatal outcomes.
October 12, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27535991/how-much-is-too-much-part-2-international-olympic-committee-consensus-statement-on-load-in-sport-and-risk-of-illness
#20
Martin Schwellnus, Torbjørn Soligard, Juan-Manuel Alonso, Roald Bahr, Ben Clarsen, H Paul Dijkstra, Tim J Gabbett, Michael Gleeson, Martin Hägglund, Mark R Hutchinson, Christa Janse Van Rensburg, Romain Meeusen, John W Orchard, Babette M Pluim, Martin Raftery, Richard Budgett, Lars Engebretsen
The modern-day athlete participating in elite sports is exposed to high training loads and increasingly saturated competition calendar. Emerging evidence indicates that inappropriate load management is a significant risk factor for acute illness and the overtraining syndrome. The IOC convened an expert group to review the scientific evidence for the relationship of load-including rapid changes in training and competition load, competition calendar congestion, psychological load and travel-and health outcomes in sport...
September 2016: British Journal of Sports Medicine
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