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Antonia Rizzuto, Massimiliano Fabozzi, Anna Settembre, Stefano Reggio, Ernesto Tartaglia, Salomone Di Saverio, Piero Angelini, Vania Silvestri, Chiara Mignogna, Raffaele Serra, Stefano De Franciscis, Leonardo De Luca, Diego Cuccurullo, Francesco Corcione
BACKGROUND: Choledocholithiasis occurs in 10-15% of patients with cholecystolithiasis. Despite the existence of many therapeutic options for the treatment of cholecystocholedocholithiasis, a sequential treatment in which pre-operative ERCP is combined with intraoperative cholangiography (IOC) and laparoscopic cholecystectomy (LC), is the most commonly accepted strategy. However, use of IOC in the "splitting treatment" of cholecystocholedocholithiasis is controversial. The aim of the present study is to investigate the utility of IOC in detecting residual stones in patients undergoing LC in the sequential treatment of common biliary duct or gallbladder stones...
March 16, 2018: International Journal of Surgery
Carles Díez-López, Josep Comín-Colet, José González-Costello
PURPOSE OF REVIEW: Iron overload cardiomyopathy (IOC) is an important predictor of prognosis in a significant number of patients with hereditary hemochromatosis and hematologic diseases. Its prevalence is increasing because of improved treatment strategies, which significantly improve life expectancy. We will review diagnosis, treatment, and recent findings in the field. RECENT FINDINGS: The development of preclinical translational disease models during the last years have helped our understanding of specific disease pathophysiological pathways that might eventually change the outcomes of these patients...
March 14, 2018: Current Opinion in Cardiology
Benjamin R Poh, Paul A Cashin, Daniel G Croagh
INTRODUCTION: Traditional teaching dictates that it may not be prudent to take the jaundiced patient to theatre for emergency laparoscopic cholecystectomy as they may experience worse outcomes following surgery. METHODS: A prospective cohort of 104 patients undergoing emergency laparoscopic cholecystectomy was stratified into two groups using a serum total bilirubin of above 50 μmol/L (2.9 mg/dL) to define the jaundiced group. Primary outcomes were morbidity and mortality rate...
March 14, 2018: World Journal of Surgery
Ronald John Maughan
No abstract text is available yet for this article.
March 14, 2018: British Journal of Sports Medicine
Ronald J Maughan, Louise M Burke, Jiri Dvorak, D Enette Larson-Meyer, Peter Peeling, Stuart M Phillips, Eric S Rawson, Neil P Walsh, Ina Garthe, Hans Geyer, Romain Meeusen, Lucas J C van Loon, Susan M Shirreffs, Lawrence L Spriet, Mark Stuart, Alan Vernec, Kevin Currell, Vidya M Ali, Richard Gm Budgett, Arne Ljungqvist, Margo Mountjoy, Yannis P Pitsiladis, Torbjørn Soligard, Uğur Erdener, Lars Engebretsen
Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition programme. Nonetheless, supplement use is widespread at all levels of sport. Products described as supplements target different issues, including (1) the management of micronutrient deficiencies, (2) supply of convenient forms of energy and macronutrients, and (3) provision of direct benefits to performance or (4) indirect benefits such as supporting intense training regimens...
March 14, 2018: British Journal of Sports Medicine
Nikolaos Tsiantis, Eva Balsa-Canto, Julio R Banga
Motivation: Optimality principles have been used to explain many biological processes and systems. However, the functions being optimized are in general unknown a priori. Here we present an inverse optimal control (IOC) framework for modeling dynamics in systems biology. The objective is to identify the underlying optimality principle from observed time-series data and simultaneously estimate unmeasured time-dependent inputs and time-invariant model parameters. As a special case, we also consider the problem of optimal simultaneous estimation of inputs and parameters from noisy data...
March 7, 2018: Bioinformatics
Romain Seil, Daniel Theisen, Håvard Moksnes, Lars Engebretsen
No abstract text is available yet for this article.
March 5, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Andrea Zanirato, Marco Damilano, Matteo Formica, Andrea Piazzolla, Alessio Lovi, Jorge Hugo Villafañe, Pedro Berjano
PURPOSE: To review the incidence of perioperative and late complications of surgery for spinal deformity (ASD). METHODS: Review of the literature. We reviewed recent literature in English to investigate the incidence of complications in ASD surgery in the perioperative (≤ 3 months post-operative) and late (> 3 months post-operative) periods. Randomized-controlled trials, non-randomized trials, cohort studies, case-control studies, and case series published in 2005 or later were included...
March 1, 2018: European Spine Journal
Yun Li, Shengpei Wang, Chuxiong Pan, Fushan Xue, Junfang Xian, Yaqi Huang, Xiaoyi Wang, Tianzuo Li, Huiguang He
BACKGROUND: The mechanism of general anesthesia (GA) has been explored for hundreds of years, but unclear. Previous studies indicated a possible correlation between NREM sleep and GA. The purpose of this study is to compare them by in vivo human brain function to probe the neuromechanism of consciousness, so as to find out a clue to GA mechanism. METHODS: 24 healthy participants were equally assigned to sleep or propofol sedation group by sleeping ability. EEG and Ramsay Sedation Scale were applied to determine sleep stage and sedation depth respectively...
2018: PloS One
Peter H Sönksen, Richard I G Holt, Walailuck Böhning, Nishan Guha, David A Cowan, Christiaan Bartlett, Dankmar Böhning
Background: Endocrine profiles have been measured on blood samples obtained immediately post-competition from 693 elite athletes from 15 Olympic Sports competing at National or International level; four were subsequently excluded leaving 689 for the current analysis. Methods: Body composition was measured by bioimpedance in a sub-set of 234 (146 men and 88 women) and from these data a regression model was constructed that enabled 'estimated' lean body mass and fat mass to be calculated on all athletes...
2018: Clinical Diabetes and Endocrinology
Cynthia J Bell, Ryan A Bell, Brad Zebrack, Ikuko Kato, Alyssa Morse, Scott C Borinstein
Adolescents and young adults (AYAs) 15-39 years old face unique challenges during cancer treatment as developmental and social needs are often disrupted to achieve cure. Developmentally appropriate supportive care for AYAs across the cancer trajectory is needed. The purpose of this review is to identify and describe instruments that measure AYA development across physical, psychological, and social domains, commenting on the instruments' psychometric properties and usefulness in clinical practice and research...
February 9, 2018: Journal of Adolescent and Young Adult Oncology
Sangita Bohara, Shyama Jain, Nita Khurana, Darilin M Shangpliang, Swapnil Agarwal, Gauri Gandhi
Background: Intraoperative cytology (IOC) is a simple and quick technique with excellent preservation of cellular details. In the present study, we have evaluated the role of IOC by various methods of smear preparation and compared it with frozen section diagnosis. A scoring system was followed for epithelial tumors for characterization and grading on the basis of cellularity, pattern, nuclear, cytoplasmic features, and background details. Materials and Methods: The study was conducted during a time span of 2 years in total 48 cases of ovarian tumors...
January 2018: Journal of Cytology
Alexandre Reynaud, Robert F Hess
Stereoscopic vision uses the disparity between the images received by the two eyes to derive three-dimensional estimates. Here, we were interested in providing a measure of the strength of binocular vision alternate to disparity processing. In particular, we wanted to assess the spatial dependence of sensitivity to detect interocular correlation (IOC). Thus we designed dichoptic stimuli composed of bandpass textures whose IOC is sinusoidally modulated at different correlation frequencies and compared sensitivity to these stimuli to that of analogous stimuli modulated in disparity...
January 1, 2018: Journal of Vision
Ziyan Wu, Catherine A Mazzola, Lori Catania, Oyindamola Owoeye, Chang Yaramothu, Tara Alvarez, Yu Gao, Xiaobo Li
AIMS: This study aimed at understanding the neurobiological mechanisms associated with inattention induced by traumatic brain injury (TBI). To eliminate the potential confounding caused by the heterogeneity of TBI, we focused on young adults postsports-related concussion (SRC). METHODS: Functional near-infrared spectroscopy (fNIRS) data were collected from 27 young adults post-SRC and 27 group-matched normal controls (NCs), while performing a visual sustained attention task...
January 22, 2018: CNS Neuroscience & Therapeutics
Julien Meyer, Guy Paré
BACKGROUND: Coordination between physicians and allied professionals is essential to the effective delivery of care services and is associated with positive patient outcomes. As information technology can radically transform how professionals collaborate, both researchers and healthcare accreditation bodies are devoting a growing interest to the means of achieving better coordination. INTRODUCTION: The primary aim of this study is to explain the extent to which and how coordination practices between pathologists, technologists, and surgeons are transformed when telepathology is being implemented...
January 3, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
Ruly Terán Hilares, Rebeca Andrade de Souza, Paulo Franco Marcelino, Silvio Silvério da Silva, Giuliano Dragone, Solange I Mussatto, Júlio César Santos
Sugarcane bagasse (SCB) hydrolysate could be an interesting source for red pigment production by Monascus ruber Tieghem IOC 2225. The influence of different wavelength of light-emitting diode (LED) at 250 μmol.m-2.s-1 of photon flux density on red pigment production by M. ruber in glucose-based medium was evaluated. Then, SCB hydrolysate was used as carbon source under the previously selected light incidence conditions. In glucose-based medium, the highest pigment production was achieved in fermentation assisted with orange LED light (8...
April 15, 2018: Food Chemistry
Brittany Ciepluch, Heather Wilson-Robles, Gwendolyn Levine, Roger Smith, Gus A Wright, Tasha Miller, Maureen T O'Brien, Kelley M Thieman Mankin
OBJECTIVE: To determine the ability of an intraoperative cell salvage (IOCS) system and a leukocyte reduction filter (LRF) to remove hemangiosarcoma (HSA) cells from canine blood. STUDY DESIGN: Cultured HSA cells were added to canine blood to simulate intraoperative hemorrhage and address hemoabdomen from ruptured splenic HSA. The blood/HSA cell mixture was processed through an IOCS, followed by LRF processing. SAMPLE POPULATION: Whole blood from 3 healthy dogs combined with cultured HSA cells...
February 2018: Veterinary Surgery: VS
Benjamin Martin, Evelyn Geok Peng Ong
AIMS: Intraoperative cholangiograms (IOC) during laparoscopic cholecystectomy have been advocated to detect biliary anomalies and intraductal calculi. However, IOC increases operative time and patient irradiation, and therefore is not universally used. We hypothesise selective IOC may be a valuable tool in children. METHODS: A retrospective case note review was performed of all children who underwent laparoscopic cholecystectomy at a single institution by a single surgeon between January 2011 and March 2017...
February 2018: Journal of Pediatric Surgery
Michel D Crema, Mohamed Jarraya, Lars Engebretsen, Frank W Roemer, Daichi Hayashi, Romulo Domingues, Abdalla Y Skaf, Ali Guermazi
BACKGROUND: Acute muscle injuries in elite athletes are responsible for a large portion of time loss injuries. AIM: To describe the frequency, the anatomic distribution, and severity of imaging-detected acute muscle injuries among athletes who competed in the Rio de Janeiro 2016 Summer Olympics. METHODS: We recorded all sports injuries reported by the National Olympic Committee medical teams and the Organising Committee medical staff during the 2016 Summer Olympics...
December 7, 2017: British Journal of Sports Medicine
Begüm Kıran, Muhittin Toman, Nurcan Buduneli, David F Lappin, Suna Toksavul, Nejat Nizam
OBJECTIVES: Implant supported single metal-ceramic crowns cemented either extraorally or intraorally were comparatively evaluated by clinical, radiologic, biomarker, and microbiological parameters. MATERIALS AND METHODS: Twelve patients with bilateral single tooth gap in the maxillary posterior region received two locking-taper implants; 4.5 mm width, 8 mm length. Selection of intraoral (IOC) or extraoral cementation (EOC) using screwless titanium abutments was done randomly...
December 6, 2017: Clinical Implant Dentistry and related Research
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