keyword
https://read.qxmd.com/read/38508100/exploring-the-association-between-suicidal-thoughts-self-injury-and-glp-1-receptor-agonists-in-weight-loss-treatments-insights-from-pharmacovigilance-measures-and-unmasking-analysis
#21
JOURNAL ARTICLE
A Guirguis, S Chiappini, G D Papanti P, R Vickers-Smith, D Harris, J M Corkery, D Arillotta, G Floresta, G Martinotti, F Schifano
INTRODUCTION: The study addresses concerns about potential psychiatric side effects of Glucagon-like peptide-1 receptor agonists (GLP-1 RA). AIM: The aim of this work was to analyse adverse drug reports (ADRs) from the Food and Drug Administration Adverse Events Reporting System (FAERS) using metformin and orlistat as comparators. METHODS: Descriptive and pharmacovigilance disproportionality analyses was performed. RESULTS: A total of 209,354 ADRs were reported, including 59,300 serious cases...
March 19, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/38506817/decoding-suicide-decedent-profiles-and-signs-of-suicidal-intent-using-latent-class-analysis
#22
JOURNAL ARTICLE
Yunyu Xiao, Kaiwen Bi, Paul Siu-Fai Yip, Julie Cerel, Timothy T Brown, Yifan Peng, Jyotishman Pathak, J John Mann
IMPORTANCE: Suicide rates in the US increased by 35.6% from 2001 to 2021. Given that most individuals die on their first attempt, earlier detection and intervention are crucial. Understanding modifiable risk factors is key to effective prevention strategies. OBJECTIVE: To identify distinct suicide profiles or classes, associated signs of suicidal intent, and patterns of modifiable risks for targeted prevention efforts. DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used data from the 2003-2020 National Violent Death Reporting System Restricted Access Database for 306 800 suicide decedents...
March 20, 2024: JAMA Psychiatry
https://read.qxmd.com/read/38503923/discontinuation-of-psychotropic-medication-a-synthesis-of-evidence-across-medication-classes
#23
REVIEW
Christiaan H Vinkers, Ralph W Kupka, Brenda W Penninx, Henricus G Ruhé, Jakob M van Gaalen, Paul C F van Haaren, Arnt F A Schellekens, Sameer Jauhar, Josep A Ramos-Quiroga, Eduard Vieta, Jari Tiihonen, Stijn E Veldman, Wim Veling, Roeland Vis, Laura E de Wit, Jurjen J Luykx
Pharmacotherapy is an effective treatment modality across psychiatric disorders. Nevertheless, many patients discontinue their medication at some point. Evidence-based guidance for patients, clinicians, and policymakers on rational discontinuation strategies is vital to enable the best, personalized treatment for any given patient. Nonetheless, there is a scarcity of guidelines on discontinuation strategies. In this perspective, we therefore summarize and critically appraise the evidence on discontinuation of six major psychotropic medication classes: antidepressants, antipsychotics, benzodiazepines, mood stabilizers, opioids, and stimulants...
March 19, 2024: Molecular Psychiatry
https://read.qxmd.com/read/38503576/a-roadmap-beyond-dispensing-for-educating-and-training-community-pharmacists-on-key-mental-health-competencies-a-mixed-methods-national-study
#24
JOURNAL ARTICLE
Hamzah Alzubaidi, Ward Saidawi, Lisa Goldstone, Basema Saddik, Abduelmula R Abduelkarem, Eman Abu-Gharbieh, Karem H Alzoubi, Catarina Samorinha
BACKGROUND: Including pharmacists in collaborative mental healthcare models has yielded positive results. Establishing processes to enhance pharmacists' mental health care capabilities is crucial for addressing the increasing burden and improving access to mental health services. OBJECTIVES: This study evaluated community pharmacists' mental health competencies and analyzed associated factors using a rigorous international framework. Additionally, it sought to identify pharmacists' training needs and support requirements as the first stop in creating a roadmap for enhancing mental healthcare through community pharmacies...
March 14, 2024: Research in Social & Administrative Pharmacy: RSAP
https://read.qxmd.com/read/38503084/mindfulness-based-cognitive-therapy-neurobiology-in-treatment-resistant-obsessive-compulsive-disorder-a-domain-related-resting-state-networks-approach
#25
JOURNAL ARTICLE
Víctor De la Peña-Arteaga, Marta Cano, Daniel Porta-Casteràs, Muriel Vicent-Gil, Neus Miquel-Giner, Ignacio Martínez-Zalacaín, Lorea Mar-Barrutia, Marina López-Solà, Jessica R Andrews-Hanna, Carles Soriano-Mas, Pino Alonso, Maria Serra-Blasco, Clara López-Solà, Narcís Cardoner
Mindfulness-based cognitive therapy (MBCT) stands out as a promising augmentation psychological therapy for patients with obsessive-compulsive disorder (OCD). To identify potential predictive and response biomarkers, this study examines the relationship between clinical domains and resting-state network connectivity in OCD patients undergoing a 3-month MBCT programme. Twelve OCD patients underwent two resting-state functional magnetic resonance imaging sessions at baseline and after the MBCT programme. We assessed four clinical domains: positive affect, negative affect, anxiety sensitivity, and rumination...
March 18, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/38502842/-correction-to-a-predictive-biomarker-model-using-quantitative-electroencephalography-in-adolescent-major-depressive-disorder-by-mcvoy-et-al-j-child-adolesc-psychopharmacol-2022-32-9-460-466-doi-10-1089-cap-2022-0041
#26
(no author information available yet)
No abstract text is available yet for this article.
March 19, 2024: Journal of Child and Adolescent Psychopharmacology
https://read.qxmd.com/read/38502361/-binge-drinking-in-early-adolescence-results-of-the-pr%C3%A3-ventionsradar-from-2016-to-2023
#27
JOURNAL ARTICLE
Reiner Hanewinkel, Julia Hansen
INTRODUCTION: In Germany, no other psychotropic substance is consumed as often and in such large quantities during adolescence as alcohol. This work aims to examine trends in binge drinking in early adolescence from 2016 to 2023. METHOD: Based on seven waves of the "Präventionsradar," which is a school-based epidemiological study in lower secondary education, the lifetime as well as the 30-day prevalence of binge drinking (for girls 4, for boys 5 alcoholic drinks on one occasion) were determined for the period from 2016 to 2023 for 12- to 15-year-olds...
March 19, 2024: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://read.qxmd.com/read/38502289/an-evidence-based-update-on-anticholinergic-use-for-drug-induced-movement-disorders
#28
JOURNAL ARTICLE
Nora Vanegas-Arroyave, Stanley N Caroff, Leslie Citrome, Jovita Crasta, Roger S McIntyre, Jonathan M Meyer, Amita Patel, J Michael Smith, Khody Farahmand, Rachel Manahan, Leslie Lundt, Samantha A Cicero
Drug-induced movement disorders (DIMDs) are associated with use of dopamine receptor blocking agents (DRBAs), including antipsychotics. The most common forms are drug-induced parkinsonism (DIP), dystonia, akathisia, and tardive dyskinesia (TD). Although rare, neuroleptic malignant syndrome (NMS) is a potentially life-threatening consequence of DRBA exposure. Recommendations for anticholinergic use in patients with DIMDs were developed on the basis of a roundtable discussion with healthcare professionals with extensive expertise in DIMD management, along with a comprehensive literature review...
March 19, 2024: CNS Drugs
https://read.qxmd.com/read/38499795/evolution-of-the-profiles-of-new-psychotropic-drug-users-before-and-during-the-covid-19-crisis-an-original-longitudinal-approach-through-multichannel-sequence-analysis-using-the-french-health-care-database
#29
JOURNAL ARTICLE
Marion Istvan, Mélanie Duval, Karl Hodel, Aurélie Aquizerate, Anicet Chaslerie, Pascal Artarit, Edouard-Jules Laforgue, Caroline Victorri-Vigneau
The COVID-19 pandemic has had a substantial impact on mental health. An increase in the use of anxiolytic, hypnotic, and antidepressant drugs has been highlighted in France, but with no information at the individual level (trajectories) or concerning patient characteristics. The objective of this study was to describe the profile of new psychotropic drug users since the beginning of the pandemic. We formed two historical cohorts using the Pays-de-la-Loire regional component of the National Health Data System (SNDS): a "COVID-19 crisis cohort" (2020-2021) and a "control cohort" (2018-2019)...
March 18, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38498202/people-with-intellectual-disabilities-dysphagia-and-post-covid-syndrome
#30
JOURNAL ARTICLE
Lance Watkins, Amit Kulkarni, Emma Webber, Paul Bassett, Kirsten Lamb, Indermeet Sawhney, Richard Laugharne, Pauline Heslop, Angela Jones, Geraldine Napier, Angela Crocker, Manoj Sivan, Rohit Shankar
People with Intellectual Disability (ID) were more likely to contract COVID-19 infection and more likely to die from the consequences. However, there is no evidence on the long-term impact of COVID-19 infection in people with ID. Post-Covid Syndrome (PCS) is an established diagnosis that requires specialist clinical support. To date there is no data on how common PCS is in people with ID, or how symptoms present. Dysphagia is identified as a clinical marker because of the known association with PCS, and the clear objective diagnostic criteria applicable through specialist assessment...
March 18, 2024: Dysphagia
https://read.qxmd.com/read/38497333/association-of-pneumonia-admission-with-polypharmacy-and-drug-use-in-community-dwelling-older-people
#31
JOURNAL ARTICLE
Hironobu Hamaya, Taro Kojima, Yukari Hattori, Masahiro Akishita
AIM: The purpose of the present study was to clarify the association of pneumonia admission with polypharmacy and specific drug use in community-dwelling older people. METHODS: Using health insurance and long-term care insurance data from Kure city in Japan, we retrospectively collected data for older community-dwelling people (aged ≥65 years) from April 2017 to March 2019. The outcome was pneumonia admission. We carried out multivariate logistic regression analysis to identify the association of pneumonia admission with polypharmacy (≥5 drugs), the use of psychotropic drugs or anticholinergics with adjustment for patient backgrounds, such as comorbidity, and the daily life independence level for the older people with disability...
March 18, 2024: Geriatrics & Gerontology International
https://read.qxmd.com/read/38494139/irritability-across-adolescence-examining-longitudinal-trajectory-stability-and-associations-with-psychopathology-and-functioning-at-age-18
#32
JOURNAL ARTICLE
Jamilah Silver, Leah Sorcher, Gabrielle A Carslon, Lea R Dougherty, Daniel N Klein
BACKGROUND: Irritability, marked by diminished frustration tolerance, holds significant implications for youth mental health treatment. Despite prior research on irritability trajectories, understanding of individual differences during adolescence remains limited. This study examines the stability and trajectory of irritability across ages 12-18, investigating associations with psychopathology and functioning at age 18. METHODS: A community sample of families with 3-year-old children (N = 518) was recruited via commercial mailing lists...
March 15, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38494136/two-multimodal-neuroimaging-subtypes-of-obsessive-compulsive-disorder-disclosed-by-semi-supervised-machine-learning
#33
JOURNAL ARTICLE
Zhipeng Ding, Tinghuizi Shang, Zhenning Ding, Xu Yang, Jiale Qi, Xiaoqing Qin, Yunhui Chen, Dan Lv, Tong Li, Jidong Ma, Chuang Zhan, Jian Xiao, Zhenghai Sun, Na Wang, Zengyan Yu, Chengchong Li, Ping Li
BACKGROUND: Obsessive-compulsive disorder (OCD) is a highly heterogeneous mental condition with a diverse symptom. Existing studies classified OCD on the basis of conventional phenomenology-based taxonomy ignoring the fact that the same subtype identified in accordance with clinical symptom may have different mechanisms and treatment responses. METHODS: This research involved 50 medicine-free patients with OCD and 50 matched healthy controls (HCs). All the participants were subjected to structural and functional magnetic resonance imaging (MRI)...
March 15, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38492550/trait-anxiety-is-associated-with-attentional-brain-networks
#34
JOURNAL ARTICLE
Víctor De la Peña-Arteaga, Pamela Chavarría-Elizondo, Asier Juaneda-Seguí, Ignacio Martínez-Zalacaín, Pedro Morgado, José Manuel Menchón, Maria Picó-Pérez, Miquel A Fullana, Carles Soriano-Mas
Trait anxiety is a well-established risk factor for anxiety and depressive disorders, yet its neural correlates are not clearly understood. In this study, we investigated the neural correlates of trait anxiety in a large sample (n = 179) of individuals who completed the trait and state versions of the State-Trait Anxiety Inventory and underwent resting-state functional magnetic resonance imaging. We used independent component analysis to characterize individual resting-state networks (RSNs), and multiple regression analyses to assess the relationship between trait anxiety and intrinsic connectivity...
March 15, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/38492329/identification-and-treatment-of-individuals-with-childhood-onset-and-early-onset-schizophrenia
#35
REVIEW
Christoph U Correll, Celso Arango, Birgitte Fagerlund, Silvana Galderisi, Martien J Kas, Stefan Leucht
Approximately 8 % of patients with schizophrenia are diagnosed before age 18, and 18 % experience their first symptoms before age 18. This narrative review explores the management of patients with early-onset schizophrenia (EOS) and childhood-onset schizophrenia (COS) from diagnosis to their transition to adult care settings. Early diagnosis of schizophrenia in children and adolescents is essential for improving outcomes, but delays are common due to overlapping of symptoms with developmental phenomena and other psychiatric conditions, including substance use, and lack of clinicians' awareness...
March 15, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/38492023/association-between-intuitive-eating-and-health-outcomes-in-outpatients-with-type-2-diabetes-a-cross-sectional-study
#36
JOURNAL ARTICLE
Olívia Garbin Koller, Vanessa Machado Menezes, Aline Busanello, Jussara Carnevale de Almeida
PURPOSE: To evaluate the association between intuitive eating and health outcomes in patients with type 2 diabetes in a cross-sectional study. METHODS: Consecutively, outpatients attending at university hospital underwent clinical, laboratory, lifestyle, and eating behavior evaluations. Intuitive eating was assessed using the Intuitive Eating Scale-2 (IES-2), and the Three Factor Eating Questionnaire-21 was adopted as a confirmatory tool for disordered eating behavior...
March 16, 2024: European Journal of Nutrition
https://read.qxmd.com/read/38491344/correlates-of-suicidal-behaviors-and-genetic-risk-among-united-states-veterans-with-schizophrenia-or-bipolar-i-disorder
#37
JOURNAL ARTICLE
Tim B Bigdeli, Peter B Barr, Nallakkandi Rajeevan, David P Graham, Yuli Li, Jacquelyn L Meyers, Bryan R Gorman, Roseann E Peterson, Frederick Sayward, Krishnan Radhakrishnan, Sundar Natarajan, David A Nielsen, Anna V Wilkinson, Anil K Malhotra, Hongyu Zhao, Mary Brophy, Yunling Shi, Timothy J O'Leary, Theresa Gleason, Ronald Przygodzki, Saiju Pyarajan, Sumitra Muralidhar, J Michael Gaziano, Grant D Huang, John Concato, Larry J Siever, Lynn E DeLisi, Nathan A Kimbrel, Jean C Beckham, Alan C Swann, Thomas R Kosten, Ayman H Fanous, Mihaela Aslan, Philip D Harvey
Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-injurious behavior, suicidal ideation, and suicidal behaviors (SB). Characterizing associations between diagnosed health problems, prior pharmacological treatments, and polygenic scores (PGS) has potential to inform risk stratification. We examined self-reported SB and ideation using the Columbia Suicide Severity Rating Scale (C-SSRS) among 3,942 SCZ and 5,414 BPI patients receiving care within the Veterans Health Administration (VHA)...
March 15, 2024: Molecular Psychiatry
https://read.qxmd.com/read/38490760/5-year-mental-health-outcomes-for-children-and-adolescents-presenting-with-psychiatric-symptoms-to-general-practitioners-in-england-a-retrospective-cohort-study
#38
JOURNAL ARTICLE
Morwenna Senior, Matthias Pierce, Vicky P Taxiarchi, Shruti Garg, Dawn Edge, Tamsin Newlove-Delgado, Sharon A S Neufeld, Kathryn M Abel
BACKGROUND: Little information is available on the clinical trajectories of children and adolescents who attend general practice (GP) with psychiatric symptoms. We aimed to examine 5-year service use in English primary care for children and adolescents with neurodevelopmental or mental health symptoms or diagnoses. METHODS: In this retrospective cohort study, we used anonymised primary care health records from the Clinical Practice Research Datalink Aurum database (CPRD-Aurum)...
April 2024: Lancet Psychiatry
https://read.qxmd.com/read/38490086/the-why-and-the-how-of-transdiagnostic-clinical-research-in-youth-psychiatry
#39
JOURNAL ARTICLE
Covadonga M Díaz-Caneja, Sinan Guloksuz
No abstract text is available yet for this article.
March 14, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/38490085/the-pros-and-cons-of-banning-electronic-cigarettes
#40
JOURNAL ARTICLE
Wim van den Brink, Jan van Amsterdam
No abstract text is available yet for this article.
March 14, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
keyword
keyword
9989
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.