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arcus senilis

Peiqing Chen, Yanan Zhu, Ke Yao
BACKGROUND: Femtosecond laser-assisted cataract surgery (FLACS) has grown in popularity among ophthalmologists as a novel technique. However, descemet membrane detachment (DMD) began to be found as the complication after FLACS. We report a case of serious DMD following FLACS due to the inappropriate incision design. CASE PRESENTATION: An 85-year-old man with apparent cornea arcus senilis underwent femtosecond laser-assisted cataract surgery in his right eye. A biplanar model was chosen for the main incision...
September 16, 2017: BMC Ophthalmology
William A Pettinger
The Hypertension Community has 3 conflicting dilemmas: a goal systolic pressure of 120 mm Hg or less (the SPRINT Trials), 40% of our 60,000,000 hypertensives still sustain blood pressures above 140/90 mm Hg, and our most potent antihypertensive drug minoxidil sits on the sidelines, imprisoned in the Food and Drug Administration's Black Box designation. My solutions to these dilemmas are: (1) review of the facts of our most potent antihypertensive drug minoxidil which is essentially free of toxicity, (2) treatment focus on the fundamental cause of high blood pressure, that is excess dietary sodium and, (3) prevention of, and/or reversal of, the fundamental mechanism of worsening hypertension, arteriolar hypertrophy...
March 2017: Journal of Cardiovascular Pharmacology
Ziya Ayhan, Taylan Ozturk, Mahmut Kaya, Gul Arikan, Uzeyir Gunenc
PURPOSE: To compare the corneal biomechanical properties and intraocular pressure (IOP) levels in patients with and without arcus senilis (AS). METHODS: Ocular response analyzer measurements were performed on the right eyes of 37 patients with AS (group 1) and 37 control eyes (group 2). Corneal hysteresis, corneal resistance factor, Goldmann-correlated IOP, and corneal compensated IOP were recorded with Ocular response analyzer. Spherical equivalent value of the refractive errors, axial length, central corneal thickness, and IOP measured with Goldmann applanation tonometer were noted for each study eyes...
July 2016: Cornea
Hassan Hashemi, Mehdi Khabazkhoob, Mohammad Hassan Emamian, Mohammad Shariati, Akbar Fotouhi
PURPOSE: To determine the prevalence of corneal arcus, its risk factors, and its relationship to ocular and visual indices. METHODS: In this cross-sectional study, 300 clusters were randomly selected from Shahroud in the north of Iran, using multistage sampling. A total of 20 people were invited to participate from each cluster. After enrollment, all optometric, biometric and ophthalmic exams were conducted on site. RESULTS: Of 6311 people invited, 5190 (82...
October 2014: Ophthalmic Epidemiology
Marina Cuchel, Eric Bruckert, Henry N Ginsberg, Frederick J Raal, Raul D Santos, Robert A Hegele, Jan Albert Kuivenhoven, Børge G Nordestgaard, Olivier S Descamps, Elisabeth Steinhagen-Thiessen, Anne Tybjærg-Hansen, Gerald F Watts, Maurizio Averna, Catherine Boileau, Jan Borén, Alberico L Catapano, Joep C Defesche, G Kees Hovingh, Steve E Humphries, Petri T Kovanen, Luis Masana, Päivi Pajukanta, Klaus G Parhofer, Kausik K Ray, Anton F H Stalenhoef, Erik Stroes, Marja-Riitta Taskinen, Albert Wiegman, Olov Wiklund, M John Chapman
AIMS: Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening condition characterized by markedly elevated circulating levels of low-density lipoprotein cholesterol (LDL-C) and accelerated, premature atherosclerotic cardiovascular disease (ACVD). Given recent insights into the heterogeneity of genetic defects and clinical phenotype of HoFH, and the availability of new therapeutic options, this Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society (EAS) critically reviewed available data with the aim of providing clinical guidance for the recognition and management of HoFH...
August 21, 2014: European Heart Journal
Yugal K Sharma, Aayush Gupta, Nitin D Chaudhari
No abstract text is available yet for this article.
July 2014: Indian Journal of Dermatology, Venereology and Leprology
Marina Macchiaiolo, Paola Sabrina Buonuomo, Paola Valente, Ippolita Rana, Francesca Romana Lepri, Michaela Veronika Gonfiantini, Andrea Bartuli
No abstract text is available yet for this article.
March 2014: Journal of Pediatrics
Sophie Acquart, Nelly Campolmi, Zhiguo He, Giacomo Pataia, Rémy Jullienne, Olivier Garraud, Frédéric Nguyen, Michel Péoc'h, Thierry Lépine, Gilles Thuret, Philippe Gain
We developed a non-invasive device to quantify transparency (T), clear corneal diameter (CCD) excluding arcus senilis, and scleral rim diameter (SRD) of stored corneas. The T value (expressed in % on a relative scale), based on the modulation transfer function principle, referred to the ratio of local contrasts of a special LED backlit chart measured with and without cornea. CCD and SRD (in mm) were automatically calculated by morphologic operations. Firstly, we assessed measurement reproducibility. We then determined the agreement of T and CCD values with 3-level scores given independently by three experts on 179 scientific corneas...
September 2014: Cell and Tissue Banking
Xin Meng, Jie Lin, Xinxiao Gao, Jia Guo, Chen Xin, Jun Wang
We report the case of a 12-year-old male who developed corneal arcus and multiple skin lesions with a 10-year history of xanthomas. The lesions appeared over his fingers, hands, elbows, knees, buttocks and feet. Laboratory studies showed a total serum cholesterol level of 752.1 mg/dL; a triglyceride level of 96.6 mg/dL; a low-density lipoprotein cholesterol level of 661.3 mg/dL. Findings were consistent with homozygous familial hypercholesterolemia. To our knowledge, this is the first such case to be reported from China...
December 2013: Indian Journal of Ophthalmology
Ahmed Al Montasir, Mainul Hasan Sadik
Familial hypercholesterolemia is a single gene disorder. It has autosomal dominant pattern of inheritance. We report a 28-year-old man who presented with acute myocardial infarction. He had xanthomas and an elevated serum low density lipoprotein cholesterol (LDL-C). His only sibling, 32-year-old brother have similar cutaneous lesions and lipid profile. His mother and maternal uncle died at a young age due to myocardial infarction. This report is to emphasize the need to clinically recognize xanthomas and its familial inheritance with elevated LDL-C, premature atherosclerosis...
March 2012: Indian Journal of Medical Sciences
Andrew W Eller, Ian R Gorovoy, Vera A Mayercik
PURPOSE: To report the first described cases of peripheral yellow corneal rings secondary to vitamin supplementation for age-related macular degeneration (ARMD). DESIGN: Retrospective single-center case series. PARTICIPANTS: The eyes of 4 patients taking vitamin supplementation for ARMD were examined at the University of Pittsburgh Medical Center Department of Ophthalmology between January 2010 and April 2011. METHODS: We reviewed the medical records of 4 patients with peripheral corneal rings receiving vitamin supplementation for ARMD...
May 2012: Ophthalmology
Bilge Ozturk Sahin, Goktug Seymenoglu, Esin F Baser
Cornea plana is a rare disease in which the cornea is flattened with a low refractive power. In addition to these features, hypermetropia, deep central corneal opacities, hazy corneal limbus, peripheral scleralization of the cornea and early arcus senilis can also be seen. Closed-angle glaucoma may occur as a result of shallow anterior chamber and narrow angle; however, open-angle glaucoma has also been reported in these patients. Measuring the real intraocular pressure (IOP) value of such eyes is difficult since tonometers are affected by corneal curvature...
December 2011: International Ophthalmology
Sujiv Vurgese, Songhomitra Panda-Jonas, Nandita Saini, Ajit Sinha, Vinay Nangia, Jost Bruno Jonas
PURPOSE: To investigate the prevalence of corneal arcus and its associations. METHODS: The Central India Eye and Medical Study was a population-based study performed in rural Central India on 4711 subjects (age, 30+ years). Corneal arcus was assessed in corneal photographs. RESULTS: The study included 952 randomly selected participants. Mean body mass index (BMI) was 19.8 ± 3.6 kg/m(2), with 786 (41.3%) subjects being underweight (BMI < 18...
December 20, 2011: Investigative Ophthalmology & Visual Science
Mette Christoffersen, Ruth Frikke-Schmidt, Peter Schnohr, Gorm B Jensen, Børge G Nordestgaard, Anne Tybjærg-Hansen
OBJECTIVE: To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population. DESIGN: Prospective population based cohort study. SETTING: The Copenhagen City Heart Study. PARTICIPANTS: 12,745 people aged 20-93 years free of ischaemic vascular disease at baseline and followed from 1976-8 until May 2009 with 100% complete follow-up...
September 15, 2011: BMJ: British Medical Journal
Antonio B Fernandez, Paul D Thompson
No abstract text is available yet for this article.
2011: BMJ: British Medical Journal
Marcus Ang, Wanling Wong, Judy Park, Renyi Wu, Raghavan Lavanya, Yingfeng Zheng, Howard Cajucom-Uy, E Shyong Tai, Tien Yin Wong
PURPOSE: To examine the association of corneal arcus to cardiovascular disease (CVD) in an adult, ethnic Indian population. DESIGN: Population-based cross-sectional study. METHODS: Population-based study of ethnic South Asian Indians 40 to 80 years of age in Singapore from June 2007 through March 2009. We obtained a 75.5% response rate (3397/4497). All participants underwent standardized interview and systemic and ocular examinations, followed by nonfasting blood sampling...
November 2011: American Journal of Ophthalmology
Renyi Wu, Tien-Yin Wong, Seang-Mei Saw, Howard Cajucom-Uy, Mohamad Rosman, Tin Aung
OBJECTIVES: To examine the association of corneal arcus with central corneal thickness (CCT), intraocular pressure (IOP), and the prevalence of primary open-angle glaucoma. METHODS: This was a population-based cross-sectional study of Malay participants aged 40 to 80 years living in Singapore. Participants underwent a standardized interview and systemic and ocular examinations, including CCT, IOP, and corneal curvature radius measurements. Corneal arcus, assessed using a slitlamp, was defined as gray-white or yellow opacity located near the periphery of the cornea but separated from the limbus by a clear zone...
November 2010: Archives of Ophthalmology
A Garcia-Rios, P Perez-Martinez, P Mata, F Fuentes, J Lopez-Miranda, R Alonso, J Caballero, N Mata, F Perez-Jimenez, J M Ordovas
BACKGROUND AND AIMS: rs17321515 SNP has been associated with variation in LDL-C, high density lipoprotein cholesterol and triglycerides concentrations. This effect has never been studied in patients with severe hypercholesterolemia. Therefore, our aims were to assess the association of the rs17321515 (TRIB1) SNP with plasma lipids concentrations and anthropometric variables and to explore the interaction between this SNP and some classic risk factors in patients with familial hypercholesterolemia (FH)...
December 2011: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Renyi Wu, Jie Jin Wang, E Shyong Tai, Tien Yin Wong
PURPOSE: To examine the relationship of corneal arcus with cardiovascular risk factors and inflammation in Malay adults living in Singapore. DESIGN: Population-based cross-sectional study. METHODS: A total of 3280 Malays aged 40-80 years (out of 4168 eligible participants; 78.7% response rate) had a standardized interview, systemic and ocular examinations, and laboratory investigations, including measurement of C-reactive protein (CRP), chronic kidney disease, and peripheral artery disease...
October 2010: American Journal of Ophthalmology
Murat Sucu, Vedat Davutoglu
A 32-year-old man was transferred to our emergency service with the diagnosis of sudden cardiopulmonary arrest. During eye examination, a typical corneal arcus was observed. The patient underwent the primary percutaneous coronary intervention. Coronary angiography showed a total occlusion of proximal left anterior descending artery. Primary coronary balloon angioplasty was successfully performed. Independently of total cholesterol, serum high-density lipoprotein cholesterol and smoking, corneal arcus has been suggested as a predictor of coronary heart disease among hyperlipidemic men...
2009: Bratislavské Lekárske Listy
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