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https://www.readbyqxmd.com/read/28187770/malaria-risk-in-young-male-travellers-but-local-transmission-persists-a-case-control-study-in-low-transmission-namibia
#1
Jennifer L Smith, Joyce Auala, Erastus Haindongo, Petrina Uusiku, Roly Gosling, Immo Kleinschmidt, Davis Mumbengegwi, Hugh J W Sturrock
BACKGROUND: A key component of malaria elimination campaigns is the identification and targeting of high risk populations. To characterize high risk populations in north central Namibia, a prospective health facility-based case-control study was conducted from December 2012-July 2014. Cases (n = 107) were all patients presenting to any of the 46 health clinics located in the study districts with a confirmed Plasmodium infection by multi-species rapid diagnostic test (RDT). Population controls (n = 679) for each district were RDT negative individuals residing within a household that was randomly selected from a census listing using a two-stage sampling procedure...
February 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28185296/a-report-of-cerebral-malaria-treated-with-automated-red-blood-cell-exchange
#2
Waseem Q Anani, Gerald P Smith, Mehraboon Irani, Kathleen E Puca
BACKGROUND: Adjunctive automated whole blood or red blood cell exchange (RBCEx) can rapidly decrease malarial hyperparasitemia. Several case reports and series suggest improvement in clinical symptomatology; however, recent Centers of Disease Control and Prevention (CDC) recommendations concluded that RBCEx has no efficacy as an adjunctive therapy. We present a case of mental status changes secondary to cerebral malaria treated with automated RBCEx resulting in rapid and dramatic neurologic improvement...
February 10, 2017: Transfusion
https://www.readbyqxmd.com/read/28173862/pre-travel-malaria-chemoprophylaxis-counselling-in-a-public-travel-medicine-clinic-in-s%C3%A3-o-paulo-brazil
#3
Tânia do Socorro Souza Chaves, Wuelton Marcelo Monteiro, Jessé Reis Alves, Marcus Lacerda, Marta Heloisa Lopes
BACKGROUND: Malaria is one of the most prevalent parasitic diseases in the world and represents a threat to travellers visiting endemic areas. Chemoprophylaxis is the prevention measure used in travel medicine, avoiding clinical manifestations and protecting against the development of severe disease and death. METHODS: Retrospective and descriptive analysis of malaria prevention data in travellers was recorded from a travel medicine clinic in São Paulo, Brazil, between January 2006 and December 2010...
February 7, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28148300/increase-in-imported-malaria-in-the-netherlands-in-asylum-seekers-and-vfr-travellers
#4
Brechje de Gier, Franciska S T Suryapranata, Mieke Croughs, Perry J J van Genderen, Monique Keuter, Leo G Visser, Michele van Vugt, Gerard J B Sonder
BACKGROUND: Malaria is a notifiable disease in the Netherlands, a non-endemic country. Imported malaria infections occur regularly among travellers, migrants and visitors. Surveillance data were analysed from 2008 to 2015. Trends in amounts of notifications among risk groups were analysed using Poisson regression. For asylum seekers, yearly incidence was calculated per region of origin, using national asylum request statistics as denominator data. For tourists, denominator data were used from travel statistics to estimate incidence per travel region up to 2012...
February 2, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28143519/severe-malaria-in-europe-an-8-year-multi-centre-observational-study
#5
Florian Kurth, Michel Develoux, Matthieu Mechain, Denis Malvy, Jan Clerinx, Spinello Antinori, Ida E Gjørup, Joaquím Gascon, Kristine Mørch, Emanuele Nicastri, Michael Ramharter, Alessandro Bartoloni, Leo Visser, Thierry Rolling, Philipp Zanger, Guido Calleri, Joaquín Salas-Coronas, Henrik Nielsen, Gudrun Just-Nübling, Andreas Neumayr, Anna Hachfeld, Matthias L Schmid, Pietro Antonini, Tilman Lingscheid, Peter Kern, Annette Kapaun, José Saraiva da Cunha, Peter Pongratz, Antoni Soriano-Arandes, Mirjam Schunk, Norbert Suttorp, Christoph Hatz, Thomas Zoller
BACKGROUND: Malaria remains one of the most serious infections for travellers to tropical countries. Due to the lack of harmonized guidelines a large variety of treatment regimens is used in Europe to treat severe malaria. METHODS: The European Network for Tropical Medicine and Travel Health (TropNet) conducted an 8-year, multicentre, observational study to analyse epidemiology, treatment practices and outcomes of severe malaria in its member sites across Europe...
January 31, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28143518/submicroscopic-plasmodium-prevalence-in-relation-to-malaria-incidence-in-20-villages-in-western-cambodia
#6
Rupam Tripura, Thomas J Peto, Christianne C Veugen, Chea Nguon, Chan Davoeung, Nicola James, Mehul Dhorda, Richard J Maude, Jureeporn Duanguppama, Krittaya Patumrat, Mallika Imwong, Lorenz von Seidlein, Martin P Grobusch, Nicholas J White, Arjen M Dondorp
BACKGROUND: Cambodia has seen a marked reduction in the incidence of Plasmodium falciparum over the past decade without a corresponding decline in Plasmodium vivax incidence. It is unknown to what extent local transmission is sustained by a chain of clinical and sub-clinical infections or by continued re-introduction via migration. Using an ultrasensitive molecular technique, 20 villages in western Cambodia were surveyed to detect the low season prevalence of P. falciparum and P. vivax and local treatment records were reviewed...
January 31, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28140603/update-malaria-u-s-armed-forces-2016
#7
(no author information available yet)
Malaria infection remains an important health threat to U.S. service members who are located in endemic areas because of long-term duty assignments, participation in shorter-term contingency operations, or personal travel. In 2016, 57 service members were diagnosed with or reported to have malaria, which is the highest number of cases since 2011 (n=124). The relatively low numbers of cases during 2012-2016 mainly reflect decreases in cases acquired in Afghanistan, a reduction due largely to the progressive withdrawal of U...
January 2017: MSMR
https://www.readbyqxmd.com/read/28137810/pfk13-independent-treatment-failure-in-four-imported-cases-of-plasmodium-falciparum-malaria-given-artemether-lumefantrine-in-the-uk
#8
Colin J Sutherland, Paul Lansdell, Mandy Sanders, Julian Muwanguzi, Donelly A van Schalkwyk, Harparkash Kaur, Debbie Nolder, Julie Tucker, Hayley M Bennett, Thomas D Otto, Matthew Berriman, Trupti A Patel, Roderick Lynn, Effrossyni Gkrania-Klotsas, Peter L Chiodini
We present case histories of four patients treated with artemether-lumefantrine for falciparum malaria in UK hospitals in 2015-16. Each subsequently presented with recurrent symptoms and Plasmodium falciparum parasitaemia within 6 weeks of treatment with no intervening travel to malarious countries. Parasite isolates, all of African origin, harboured variants at some candidate resistance loci. No evidence of pfk13-mediated artemisinin resistance was found. Vigilance for signs of unsatisfactory antimalarial efficacy among imported cases of malaria is recommended...
January 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28129766/severe-plasmodium-vivax-infection-in-korea
#9
Jae Hyoung Im, Hea Yoon Kwon, JiHyeon Baek, Seong Wook Park, Areum Durey, Kyung Hee Lee, Moon-Hyun Chung, Jin-Soo Lee
BACKGROUND: Although severe malaria by Plasmodium vivax has been increasingly reported, there are marked variations in the type and rate of the complications by geographic area. This is possibly because of the presence of concurrent falciparum malaria or bacteraemia, and of differences in underlying immune status among the infected subjects. Furthermore, published studies on P. vivax in temperate regions are limited. The present study investigated severe vivax malaria in Korea, where only vivax malaria occurs...
January 28, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28122576/response-to-fever-and-utilization-of-standby-emergency-treatment-sbet-for-malaria-in-travellers-to-southeast-asia-a-questionnaire-based-cohort-study
#10
Christof D Vinnemeier, Camilla Rothe, Benno Kreuels, Marylyn M Addo, Sabine Vygen-Bonnet, Jakob P Cramer, Thierry Rolling
BACKGROUND: Guidelines in several European countries recommend standby emergency treatment (SBET) for travellers to regions with low or medium malaria transmission instead of continuous chemoprophylaxis: travellers are advised to seek medical assistance within 24 h in case of fever and to self-administer SBET only if they are not able to consult a doctor within the time period specified. Data on healthcare-seeking behaviour of febrile travellers and utilization of SBET is however scarce as only two studies were performed in the mid-1990s...
January 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28122572/artemether-lumefantrine-and-liver-enzyme-abnormalities-in-non-severe-plasmodium-falciparum-malaria-in-returned-travellers-a-retrospective-comparative-study-with-quinine-doxycycline-in-a-portuguese-centre
#11
André Silva-Pinto, Rogério Ruas, Francisco Almeida, Raquel Duro, André Silva, Cândida Abreu, António Sarmento
BACKGROUND: Artemisinin-based therapy is the current standard treatment for non-severe malaria due to Plasmodium falciparum. The potential for asymptomatic liver toxicity of this therapy and its implication in clinical practice is currently unknown. The aim of this study is to assess the hepatic function in patients treated with a standard three-day artemisinin-based regimen and to compare it with the quinine-doxycycline regimen. METHODS: Retrospective and comparative study of returned adult travellers admitted with non-severe P...
January 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28104695/infectious-disease-risk-and-international-tourism-demand
#12
Jaume Rosselló, Maria Santana-Gallego, Waqas Awan
CONTEXT:  For some countries, favourable climatic conditions for tourism are often associated with favourable conditions for infectious diseases, with the ensuing development constraints on the tourist sectors of impoverished countries where tourism's economic contribution has a high potential. This paper evaluates the economic implications of eradication of Malaria, Dengue, Yellow Fever and Ebola on the affected destination countries focusing on the tourist expenditures. METHODS:  A gravity model for international tourism flows is used to provide an estimation of the impact of each travel-related disease on international tourist arrivals...
January 18, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28104109/mixed-species-malaria-infection-in-midwestern-returned-traveler
#13
Eric Abston, Sydney Rooney, Melinda Johnson, Ambar Haleem
No abstract text is available yet for this article.
January 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28100237/surveillance-and-response-for-high-risk-populations-what-can-malaria-elimination-programmes-learn-from-the-experience-of-hiv
#14
REVIEW
Jerry O Jacobson, Carmen Cueto, Jennifer L Smith, Jimee Hwang, Roly Gosling, Adam Bennett
To eliminate malaria, malaria programmes need to develop new strategies for surveillance and response appropriate for the changing epidemiology that accompanies transmission decline, in which transmission is increasingly driven by population subgroups whose behaviours place them at increased exposure. Conventional tools of malaria surveillance and response are likely not sufficient in many elimination settings for accessing high-risk population subgroups, such as mobile and migrant populations (MMPs), given their greater likelihood of asymptomatic infections, illegal risk behaviours, limited access to public health facilities, and high mobility including extended periods travelling away from home...
January 18, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28091389/trali-syndrome-during-the-treatment-of-a-plasmodium-falciparum-malaria-case
#15
Hülya Çaşkurlu, Rahman Nurmuhammedov, Zarni Htway
Malaria, which is one of the three most important infectious diseases globally, is endemic in many areas of the world. Plasmodium falciparum is not endemic to Turkey but can be seen after travel to epidemic countries. Transfusion-related acute lung injury (TRALI) syndrome is a rare disease, which may develop following the transfusion of all types of blood products, including plasma. Here we describe a case of TRALI syndrome in a 29-year-old male, who presented with fever after 15 days of returning from a business trip to Burkina Faso...
December 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28078947/monitoring-of-plasmodium-infection-in-humans-and-potential-vectors-of-malaria-in-a-newly-emerged-focus-in-southern-iran
#16
Mohsen Kalantari, Zahra Soltani, Mostafa Ebrahimi, Masoud Yousefi, Masoumeh Amin, Ayda Shafiei, Kourosh Azizi
Despite control programs, which aim to eliminate malaria from Iran by 2025, transmission of malaria has not been removed from the country. This study aimed to monitor malaria from asymptomatic parasitaemia and clinical cases from about one year of active case surveillance and potential vectors of malaria in the newly emerged focus of Mamasani and Rostam, southern Iran during 2014-2015. Samples were collected and their DNAs were extracted for Polymerase Chain Reaction (PCR) assay using specific primers for detection of Plasmodium species...
February 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28061871/lamp-kit-for-diagnosis-of-non-falciparum-malaria-in-plasmodium-ovale-infected-patients
#17
Juan Cuadros, Alexandra Martin Ramírez, Iveth J González, Xavier C Ding, Ramon Perez Tanoira, Gerardo Rojo-Marcos, Peña Gómez-Herruz, Jose Miguel Rubio
BACKGROUND: Microscopy and rapid diagnosis tests have a limited sensitivity in diagnosis of malaria by Plasmodium ovale. The LAMP kit (LoopAMP®) can be used in the field without special equipment and could have an important role in malaria control programmes in endemic areas and for malaria diagnosis in returned travellers. The performance of the Pan primer of the kit in detecting malaria by P. ovale was compared with the results of standard nPCR in samples of patients returning from P...
January 7, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28006651/identification-of-dengue-type-2-virus-in-febrile-travellers-returning-from-burkina-faso-to-france-related-to-an-ongoing-outbreak-october-to-november-2016
#18
Carole Eldin, Philippe Gautret, Antoine Nougairede, Mélanie Sentis, Laetitia Ninove, Nadia Saidani, Matthieu Million, Philippe Brouqui, Remi Charrel, Philippe Parola
Dengue fever is rarely reported in travellers returning from Africa. We report two cases of dengue fever in travellers returning from Burkina Faso to France. One of them presented a severe dengue fever with ALT > 1,000 IU/L and pericarditis. Serotype 2 was identified. The cases reflect a large ongoing outbreak with over 1,000 reported cases between August and November in the capital city. Clinicians should consider dengue fever in malaria-negative febrile travellers returning from Africa.
December 15, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28000753/plasmodium-falciparum-malaria-importation-from-africa-to-china-and-its-mortality-an-analysis-of-driving-factors
#19
Shengjie Lai, Nicola A Wardrop, Zhuojie Huang, Claudio Bosco, Junling Sun, Tomas Bird, Amy Wesolowski, Sheng Zhou, Qian Zhang, Canjun Zheng, Zhongjie Li, Andrew J Tatem, Hongjie Yu
Plasmodium falciparum malaria importation from Africa to China is rising with increasing Chinese overseas investment and international travel. Identifying networks and drivers of this phenomenon as well as the contributors to high case-fatality rate is a growing public health concern to enable efficient response. From 2011-2015, 8653 P. falciparum cases leading to 98 deaths (11.3 per 1000 cases) were imported from 41 sub-Saharan countries into China, with most cases (91.3%) occurring in labour-related Chinese travellers...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27986683/high-rate-of-treatment-failures-in-nonimmune-travelers-treated-with-artemether-lumefantrine-for-uncomplicated-plasmodium-falciparum-malaria-in-sweden-retrospective-comparative-analysis-of-effectiveness-and-case-series
#20
Klara Sondén, Katja Wyss, Irina Jovel, Antero Vieira da Silva, Anton Pohanka, Muhammad Asghar, Manijeh Vafa Homann, Lars L Gustafsson, Urban Hellgren, Anna Färnert
BACKGROUND: Artemisinin-based combination therapy (ACT) is the first-line treatment of Plasmodium falciparum malaria. Since the introduction of artemether-lumefantrine (AL) for treatment of uncomplicated malaria in Sweden, treatment failures have been reported in adults. METHODS: A retrospective comparative analysis of treatment regimen for P. falciparum malaria in adults in Stockholm during 2000-2015 was performed to evaluate the effectiveness of AL. Parasite genotyping and drug concentrations were investigated in the AL treatment failures...
October 24, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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