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Kathryn P White
Given the unparalleled popularity of botanicals in the United States, it is safe to say that almost every psychopharmacological prescriber will see some patients using Chinese herbs. Data show that between 36% and 42% of Americans use complementary and alternative medicine (CAM) each year and that persons suffering from depression and anxiety (67%) use CAM services significantly more than do their nonanxious and nondepressed counterparts (39%). This article gives an overview of several classical Chinese medical single herbs and herbal formulas commonly used for persons with psychiatric disorders and discusses some of the herbs that have the potential to interact with various pharmaceutical drugs...
December 2009: Experimental and Clinical Psychopharmacology
Guy Bernard Bantsiele, Danièle Bentué-Ferrer, Noëlla Amiot, Hervé Allain, Michel Bourin, Jean-Michel Reymann
We used two validated psychopharmacological methods, the forced swimming test (FST 20 min and 5 min) and the elevated plus-maze (EPM), to quantify depression-like and anxiety-like behavior induced by transient global cerebral ischemia in the rat. We also validated use of these methods for the study of antidepressant (imipramine) and anti-anxiety drugs (diazepam). Twelve days after surgery to provoke transient global ischemia, spontaneous motor activity was 40% higher in ischemic rats than in sham-operated controls...
December 2004: Fundamental & Clinical Pharmacology
No abstract text is available yet for this article.
January 1965: Annales Médico-psychologiques
John P Gluck, Jordan Bell
RATIONALE: The ethical debate concerning the use of animals in biomedical and pharmacological research continues to be replete with misunderstandings about whether animals have moral standing. OBJECTIVES: This article briefly reviews the central ethical positions and their relationship to the basic parameters of research regulation from an international perspective. The issues associated with the validation of animal models will then be discussed. Finally, suggestions for empirical ethics research will be presented...
December 2003: Psychopharmacology
Barbara Y Whitman, Susan Myers, Aaron Carrel, David Allen
INTRODUCTION: Prader-Willi syndrome (PWS) is characterized by obesity, hypotonia, hypogonadism, hyperphagia, short stature, and a neurobehavioral profile that includes cognitive deficits, learning problems, and behavioral difficulties that increase in both quantity and severity over time. PWS results from an alteration in the molecular composition of a critical region of C#15q. Morbid obesity resulting from hyperphagia is amplified by decreased energy expenditure and reduced physical activity...
February 2002: Pediatrics
M B Keller, R M Hirschfeld, D Hanks
Whether depression is a single disease that varies from mild to severe, with varying episode durations and difficult course patterns, or whether it is an umbrella diagnosis representing depressive subtypes with different psychological and biological characteristics has been debated by clinicians and researchers for many years. However, most scientists now agree that understanding the heterogeneous subtypes of depression allows for greater accuracy in describing and differentiating patients suffering from depression and, therefore, greater precision in describing the most efficacious treatment plan...
August 1997: Journal of Affective Disorders
P Wessely
Headaches form an essential part of the syndrome after concussion of the brain. The origin of these may be extracranial (neuralgias in scar tissue and hematomas, neuralgiform headache as a result of injury to the cervical spine) as well as diffuse in the sense of vasomotr cephalalgia which are due to central regulation disorders of the circulation caused by psychogenic mechanisms and compensatory neurosis. Methods of therapy include the use of vasoactive substances especially for vasomotor cephalalgia, immobilisation and local anesthesia in neuralgias, and psychopharmocological as well as psychotherapeutic aid in psychogenic complaints...
April 8, 1977: MMW, Münchener Medizinische Wochenschrift
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