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https://www.readbyqxmd.com/read/29766202/photochemical-device-for-selective-detection-of-phenol-in-aqueous-solutions
#1
Nianbing Zhong, Ming Chen, Zhengkun Wang, Xin Xin, Bingxin Li
We demonstrate that a lab-on-a-chip device (hereafter termed a photochemical phenol sensor) that integrates a photocatalytic long-period fiber grating (PLPFG), fiber Bragg grating (FBG), polymer membrane, ultraviolet (UV) visible light, and microchannels can be exploited to selectively detect phenol in aqueous solutions. The novel PLPFG consisted of a thinned long-period fiber grating (LPFG) and a UV-visible-light-driven Er3+:YAlO3/SiO2/TiO2 (EYST) coating. The polymer membrane with high phenol permselectivity was synthesized using PEBA2533 doped with β-cyclodextrin and was wrapped around the EYST surface, thus forming a microchannel between the membrane and PLPFG to enable the injection and outflow of standard analytes...
May 16, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29756477/anti-hyperglycemic-and-anti-inflammatory-activities-of-polyphenolic-rich-extract-of-syzygium-cumini-linn-leaves-in-alloxan-induced-diabetic-rats
#2
Basiru O Ajiboye, Oluwafemi A Ojo, Olivia S Akuboh, Okesola M Abiola, Olajumoke Idowu, Aliyu O Amuzat
In this study, anti-hyperglycemic and anti-inflammatory activities of polyphenolic-rich extract of Syzygium cumini leaves in alloxan-induced diabetic rats were determined. Diabetes was induced by a single intraperitoneal injection of alloxan (150 mg/kg body weight) in female Wistar rats. The rats were orally administered with 400 mg/kg free phenol, 400 mg/kg bound phenol, and 5 mg/kg metformin, respectively. On the 14th day of oral administration, the animals were sacrificed, anti-hyperglycemic and anti-inflammatory were assessed...
January 2018: Journal of evidence-based integrative medicine
https://www.readbyqxmd.com/read/29746935/summer-savory-satureja-hortensis-l-extract-phytochemical-profile-and-modulation-of-cisplatin-induced-liver-renal-and-testicular-toxicity
#3
Tatjana Boroja, Jelena Katanić, Gvozden Rosić, Dragica Selaković, Jovana Joksimović, Danijela Mišić, Vesna Stanković, Nemanja Jovičić, Vladimir Mihailović
The aim of our study was to examine the potential ameliorating effect of the methanolic extract of Satureja hortensis L. (summer savory) aerial parts against cisplatin-induced oxidative damage in renal, hepatic, and testicular tissues. S. hortensis methanol extract at the doses of 50, 100 and 200 mg/kg of body weight were orally administered to Wistar rats once daily for 10 days. Toxicity was induced by intraperitoneal injection of a single dose of cisplatin (7.5 mg/kg of body weight) on the 5th day of the experiment...
May 7, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29744610/walnut-phenolic-extract-inhibits-nuclear-factor-kappab-signaling-in-intestinal-epithelial-cells-and-ameliorates-experimental-colitis-and-colitis-associated-colon-cancer-in-mice
#4
Seong-Joon Koh, Youn-I Choi, Yuri Kim, Yoo-Sun Kim, Sang Woon Choi, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee
PURPOSE: Walnuts (Juglans regia) are known to have anti-cancer and immunomodulatory effects. However, little information is available on the effects of walnut phenolic extract (WPE) on intestinal inflammation and colitis-associated colon cancer. METHODS: COLO205 cells were pretreated with WPE and then stimulated with tumor necrosis factor (TNF)-α. In the acute colitis model, wild type mice (C57BL/6) were administered 4% dextran sulfate sodium (DSS) for 5 days. In the chronic colitis model, interleukin (IL)-10-/- mice were administered with either the vehicle or WPE (20 mg/kg) by oral gavage daily for 2 weeks...
May 9, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29727782/determination-of-flavanols-by-liquid-chromatography-with-fluorescence-detection-application-to-the-characterization-of-cranberry-based-pharmaceuticals-through-profiling-and-fingerprinting-approaches
#5
Inal Bakhytkyzy, Oscar Nuñez, Javier Saurina
In this work, a new method based on reversed-phase high-performance liquid chromatography (HPLC) with fluorescence detection (FLD) was established for the determination of catechins and related oligomeric proanthocyanidins (PACs) in cranberry-based pharmaceuticals. Compounds were recovered by liquid extraction using methanol/water/hydrochloric acid (60:39:1, v:v:v) as the extraction solvent. The chromatographic separation was carried out using a core-shell C18 column under an elution program based on 0.1% formic acid in water and methanol as the components of the mobile phase...
April 24, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29683521/ionic-liquid-based-headspace-in-tube-liquid-phase-microextraction-coupled-with-capillary-electrophoresis-for-sensitive-detection-of-phenols
#6
Mei-E Yue, Qiaoyan Lin, Jie Xu, Ting-Fu Jiang
An ionic liquid-based headspace in-tube liquid-phase microextraction (IL-HS-ITLPME) in-line coupled with capillary electrophoresis (CE) is proposed. The method is capable of quantifying trace amounts of phenols in environmental water samples. In the newly developed method, simply by placing a capillary injected with IL in the HS above the aqueous sample, volatile phenols were extracted into the IL acceptor phase in the capillary. After extraction, electrophoresis of the phenols in the capillary was carried out...
April 23, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29677459/hepatoprotective-and-antioxidant-properties-of-the-aqueous-extract-of-olea-europaea-leaves-against-diclofenac-induced-liver-damages-in-mice
#7
Rawya Soussi, Najla Hfaiedh, Fatma Guesmi, Mohsen Sakly, Khémais Ben Rhouma
Historically, olive tree "Olea europaea" is one of the most important fruit trees in Mediterranean countries. Several studies suggest that olive leaf is a significant source of bioactive phenolic compounds compared to olive oil and fruits. This study was undertaken to investigate, the protective effect of the aqueous extract of « Chemlali » olive leaves against diclofenac-induced damages in liver and haematological alterations in swiss albinos mice. For this, twenty-eight mice were divided into four groups: a control group, a diclofenac-treated group (2...
April 20, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29676126/-hplc-uv-fingerprints-and-chemical-pattern-recognition-of-ilicis-pubescentis-radix
#8
Ming-Juan Zhu, Guo-Jun Kuang, Wei Gao, Huan Yi, Zhong-Xiang Zhao, Yuan Zhou, Pin-Qing Wei, Qiong-Feng Liao, Lei Zhang
The present study is to establish the fingerprints for the quality evaluation of Ilicis Pubescentis Radix by HPLC-UV. The chromatographic conditions were defined as Phenomenex Luna C₁₈(4.6 mm × 250 mm, 5 μm). Mobile phase was acetonitrile-0.05% phosphoric acid in gradient elution, and the flow rate was 0.8 mL·min⁻¹.Column temperature was 30 °C and the injection volume was 10 μL.The detection wavelength was 210 nm. According to the similarity evaluation, the chemometric method was used to assess the quality of Ilicis Pubescentis Radix...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29675072/phenol-versus-botulinum-toxin-a-injection-in-ambulatory-cerebral-palsy-spastic-diplegia-a-comparative-study
#9
Nitesh Gonnade, Vaibhav Lokhande, Mohammed Ajij, Anil Gaur, Kamalakant Shukla
The aim of this study is to compare the treatment effectiveness of botulinum toxin type A (BTX-A) and phenol blocks in the management of lower limb spasticity and to measure improvement in gross motor functional outcome in children with cerebral palsy (CP). This is a hospital-based prospective, noncontrolled randomized study that took place in a tertiary care center. A total of 61 ambulatory children with CP spastic diplegia, aged from 4 to 10 years, were randomly divided into two groups and included in this study...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29669498/an-indian-desert-shrub-hiran-chabba-farsetia-hamiltonii-royle-exhibits-potent-antioxidant-and-hepatoprotective-effect-against-iron-overload-induced-liver-toxicity-in-swiss-albino-mice
#10
Tapasree Basu, Bipul Kumar, Anil Khushalrao Shendge, Sourav Panja, Heerak Chugh, Hemant K Gautam, Nripendranath Mandal
BACKGROUND: Farsetia hamiltonii Royle, also known as Hiran Chabba grows in desert regions. It is widely used as folk medicine to treat joint pains, diarrhea and diabetes. However, its antioxidant and iron chelation abilities both in vitro and in vivo have not yet been investigated. METHODS: The 70% methanolic extract of F.hamiltonii (FHME) was investigated for its free radical scavenging and iron chelation potential, in vitro. An iron-overload situation was established by intraperitoneal injection of iron-dextran in Swiss albino mice, followed by oral administration of FHME...
April 18, 2018: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/29665653/upregulation-of-ppar-%C3%AE-mediates-the-renoprotective-effect-of-omega-3-pufa-and-ferulic-acid-in-gentamicin-intoxicated-rats
#11
Nahla E El-Ashmawy, Naglaa F Khedr, Hoda A El-Bahrawy, Sara A Helal
Ferulic acid (FrA) is a natural product containing phenolic compounds. ω-3 PUFA is the major constituent of fish oil. The aim of this study was to investigate the renoprotective role of FrA and FO in gentamicin (GM)-induced nephrotoxicity in rats. Forty four male rats were divided equally into 4 groups: Control group, GM group, FrA + GM group and FO + GM group. Each of the treated groups was injected with GM (40 mg/kg) i.p. for 9 consecutive days. FrA (100 mg/kg) and FO (5 mL/kg) were given to rats orally daily for 10 days prior to GM and then concomitantly with GM for additional 9 days...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29629570/modulatory-effects-of-rosemary-leaves-aqueous-extraction-against-oxidative-stress-and-related-damages-in-experimental-model-of-ccl4-induced-cardiac-toxicity-in-mice
#12
Houda Hamed, Khaled Bellassoued, Noura Brahmi, Ahmed Gargouri, Zied Ghannoudi, Abdelfattah El Feki
Rosmarinus officialis L., Lamiaceae, has been traditionally used in Tunisia to treat several diseases. The aim of the present study is to analyze the cardiopreventive effect of Aqueous Extract of Rosemary (Rosmarinus officinalis) Leaves (AERL) against oxidative stress induced by carbon tetrachloride in experimental mice. The current study was performed on female Wistar mice divided into four groups of seven animals each. Cardiotoxity was induced by a single intraperitoneal injection of CCl4 (10ml/kg in 0.3 % olive oil) in mice which were gavaged daily with 100 mg of AERL for 15 days...
April 9, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29607788/inhibitory-effect-of-filipendula-ulmaria-on-mammary-carcinogenesis-induced-by-local-administration-of-methylnitrosourea-to-target-organ-in-rats
#13
Vladimir G Bespalov, Valerij A Alexandrov, Galina I Vysochina, Vera A Kostikova, Alexandr L Semenov, Denis A Baranenko
BACKGROUND: The meadowsweet (Filipendula ulmaria (L.) Maxim.) may have a cancer prophylactic activity, since its extracts exhibits antioxidant, antiinflammatory and other effects. We investigated the ability of a meadowsweet decoction to inhibit mammary carcinogenesis induced by intramammary injections of methylnitrosourea (MNU) to the target organ in rats. MATERIALS AND METHODS: The chemical composition of meadowsweet extracts was studied by traditional methods...
April 2, 2018: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29604592/quercus-dilatata-lindl-ex-royle-ameliorates-bpa-induced-hepatotoxicity-in-sprague-dawley-rats
#14
Syeda Tayyaba Batool Kazmi, Muhammad Majid, Sonia Maryam, Aymen Rahat, Madiha Ahmed, Muhammad Rashid Khan, Ihsan Ul Haq
Quercus dilatata Lindl. ex Royle was evaluated for in vitro polyphenol content and antioxidant potential as well as in vivo protective role against bisphenol A (BPA) induced hepatotoxicity. The distilled water-acetone (QDDAE) and methanol-ethyl acetate (QDMEtE) extracts were standardized and administered in high (300 mg/kg body weight (BW) and low (150 mg/kg BW) doses to Sprague Dawley rats, injected with BPA (25 mg/kg BW). Silymarin (50 mg/kg BW) was used as positive control. Subsequently, blood and liver homogenates were collected after four weeks of treatment, and the defensive effects of both extracts against oxidative damage and genotoxicity were assessed via hematological and biochemical investigations, determination of endogenous expression of enzymes as well as levels of free radicals and comet assay...
March 28, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29599640/the-effects-of-4-hydroxybenzoic-acid-identified-from-bamboo-dendrocalamus-asper-shoots-on-kv1-4-channel
#15
Jingli Zhang, Fatin H Mohamad, Jia Hui Wong, Habsah Mohamad, Abdul Hadi Ismail, Abdul Aziz Mohamed Yusoff, Hasnah Osman, Kok Tong Wong, Zamzuri Idris, Jafri Malin Abdullah
Background: Bamboo shoot has been used as a treatment for epilepsy in traditional Chinese medicine for generations to treat neuronal disorders such as convulsive, dizziness and headaches. 4-hydroxybenzoic acid (4-hba) is a non-flavonoid phenol found abundantly in Dendrocalamus asper shoots (bamboo), fruits (strawberries and apples) and flowers. Kv1.4 is a rapidly inactivating Shaker -related member of the voltage-gated potassium channels with two inactivation mechanisms; the fast N-type and slow C-type...
February 2018: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/29587597/ellagic-acid-as-a-potential-antioxidant-alleviates-methotrexate-induced-hepatotoxicity-in-male-rats
#16
Saeed Mehrzadi, Mehrnaz Mehrabani, Ali Reza Malayeri, Masoumeh Bakhshayesh, Heibatullah Kalantari, Mehdi Goudarzi
BACKGROUND: Hepatotoxicity is one of the most life-threatening side-effects of Methotrexate therapy. Former studies highlighted the significance of oxidative stress in promoting Methotrexate-induced hepatotoxicity (MIH). Hence, the current study investigated the protective effect of Ellagic acid (EA), a poly-phenolic antioxidant, against MIH. METHODS: Twenty-eight male Wistar rats were grouped into four sets: group 1 (control), group 2 (injected intraperitoneally with 20 mg/kg of Methotrexate on the 9th day), group 3 (treated orally with 10 mg/kg/day of EA for 10 days and injected with Methotrexate on the 9th day) and group 4 (treated with EA for 10 days)...
March 28, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29569071/coloproctology-procedure-clinic-a-novel-service-developed-to-reduce-suffering-of-patients-with-bleeding-per-rectum
#17
Yasir Bashir, Bernadette McGovern, Mohammed Tahtouh, Tahir Abbasi, Maria Murphy, Paul Neary
AIMS: Evaluation of the role and impact of introducing a dedicated coloproctology procedure clinic in tertiary referral colorectal unit. METHODS: A retrospective analysis of 126 consecutive patients managed in the coloproctology clinic between March2015 and September 2016 was carried out. All patients were preselected for attendance based on symptom-based protocol. RESULTS: Based on the information available in GP referrals, 126 patients with bleeding per rectum with low risk of cancer were re-triaged from the general outpatient to dedicated coloproctology procedure clinic...
March 22, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29560632/-effect-of-different-stimulating-strength-of-electroacupuncture-on-gastrointestinal-motility-and-rhoa-rock-signaling-in-gastric-antral-smooth-muscle-in-diabetic-gastroparesis-rats
#18
Xue-Fen Wu, Xiao-Li Chen, Xue-Na Zheng, Xin Guo, Zhi-Qiang Xie, Li Liu, Xin-Ran Wei, Zeng-Hui Yue
OBJECTIVE: To observe the effect of different strength of electroacupuncture (EA) stimulation on gastrointestinal motility and Ras homolog gene family member (RhoA)/Rho associated coiled-coil forming protein kinase (ROCK) signaling in diabetic gastroparesis (DGP) rats, so as to reveal the underlying mechanisms of EA for improving DGP. METHODS: Sixty SD rats were randomly and equally divided into blank control, DGP model, weak EA, medium EA, and strong EA groups ( n =12 rats in each)...
March 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29555357/preparation-of-polymer-monolithic-column-functionalized-by-arsonic-acid-groups-for-mixed-mode-capillary-liquid-chromatography
#19
Zhang-Na Qin, Qiong-Wei Yu, Ren-Qi Wang, Yu-Qi Feng
A mixed-mode polymer monolithic column functionalized by arsonic acid groups was prepared by single-step in situ copolymerization of monomers p-methacryloylaminophenylarsonic acid (p-MAPHA) and pentaerythritol triacrylate (PETA). The prepared poly(p-MAPHA-co-PETA) monolithic column has a homogeneous monolithic structure with good permeability and mechanical stability. Zeta potential measurements reveal that the monolithic stationary phase holds a negative surface charge when the mobile phase resides in the pH range of 3...
March 5, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29548829/lab-scale-evaluation-of-aerated-burial-concept-for-treatment-and-emergency-disposal-of-infectious-animal-carcasses
#20
Jacek A Koziel, Heekwon Ahn, Thomas D Glanville, Timothy S Frana, J Hans van Leeuwen, Lam T Nguyen
Nearly 55,000 outbreaks of animal disease were reported to the World Animal Health Information Database between 2005 and 2016. To suppress the spread of disease, large numbers of animal mortalities often must be disposed of quickly and are frequently buried on the farm where they were raised. While this method of emergency disposal is fast and relatively inexpensive, it also can have undesirable and lasting impacts (slow decay, concerns about groundwater contamination, pathogens re-emergence, and odor). Following the 2010 foot-and-mouth disease outbreak, the Republic of Korea's National Institute of Animal Science funded research on selected burial alternatives or modifications believed to have potential to reduce undesirable impacts of burial...
March 13, 2018: Waste Management
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