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Post-stroke cognitive impairment

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https://www.readbyqxmd.com/read/29451096/elevated-crp-at-admission-predicts-post-stroke-cognitive-impairment-in-han-chinese-patients-with-intracranial-arterial-stenosis
#1
Jian Guo, Wei Su, Jinhuan Fang, Ning Chen, Muke Zhou, Yang Zhang, Li He
OBJECTIVES: Elevated C-reactive protein (CRP) levels have been associated with cognitive deficits in certain patient populations, but whether this is also true of ischemic stroke patients is controversial. This study aims to examine the possible association between CRP concentration and post-stroke cognitive impairment (PSCI) in Han Chinese patients and to determine whether this association depends on intracranial arterial stenosis (ICAS). METHODS: Patients with mild or moderate stroke admitted to a large regional medical center in Western China were consecutively enrolled in our study...
February 16, 2018: Neurological Research
https://www.readbyqxmd.com/read/29448162/cognitive-motor-dual-task-interference-modulates-mediolateral-dynamic-stability-during-gait-in-post-stroke-individuals
#2
R Tisserand, S Armand, G Allali, A Schnider, S Baillieul
Gait asymmetry and dynamic balance impairments observed in post-stroke individuals increase their risk of fall. Moreover, walking while performing a cognitive task (i.e. dual-task) disturbs the control of balance in post-stroke individuals. Here we investigated the mediolateral dynamic stability in twenty-two community-dwelling participants (12 post-strokes and 10 healthy controls) while walking in single-task (normal gait) and four different dual-tasks (cognitive-motor interference). Positions of the extrapolated center of mass and mediolateral widths of both margin of stability and base of support were extracted from 35 marker trajectories...
February 12, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29427575/rhythm-perception-and-production-abilities-and-their-relationship-to-gait-after-stroke
#3
Kara K Patterson, Jennifer S Wong, Svetlana Knorr, Jessica A Grahn
OBJECTIVES: To assess rhythm abilities, describe their relationship to clinical presentation, and to determine if rhythm production independently contributes to temporal gait asymmetry post-stroke. DESIGN: Cross-sectional. SETTING: Large urban rehabilitation hospital and university. PARTICIPANTS: Individuals with subacute and chronic stroke (n=39) and data for healthy adults extracted from a pre-existing database (n=21)...
February 7, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29427168/diagnostic-test-accuracy-of-the-montreal-cognitive-assessment-in-the-detection-of-post-stroke-cognitive-impairment-under-different-stages-and-cutoffs-a-systematic-review-and-meta-analysis
#4
Dan Shi, Xiao Chen, Zheng Li
The purposes of this review were to give the optimal cutoffs of the Montreal Cognitive Assessment (MoCA) by comparing sensitivity and specificity under different cutoffs and compare the MoCA with other screening tools in post-stroke cognitive impairment (PSCI) determined by a neuropsychological evaluation. Articles were derived from a systematic search in PubMed, Web of science, Embase, and CINAHL and were assessed for internal validity by the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). The figure of risk of bias was made by Review Manager 5...
February 9, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29423616/frequency-and-predictors-of-post-stroke-delirium-in-prospective-observational-polish-study-propolis
#5
P Pasinska, K Kowalska, E Klimiec, A Szyper-Maciejowska, A Wilk, A Klimkowicz-Mrowiec
Delirium is the most common and serious neurobehavioral complication in acute hospital admissions. Some patients develop signs of delirium but do not meet all diagnostic criteria. Stroke is a major risk factor for delirium. The aim of this prospective study was to build a predictive model for delirium and subsyndromal post-stroke delirium. Patients with stroke were screened for delirium during the first 7 days after admission. Delirium was diagnosed according to DSM-V criteria. Baseline demographic, biochemical, stroke-related data, medications used, neurological deficit, and premorbid cognitive and functional impairment were assessed...
February 8, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29409115/expression-of-nerve-growth-factor-carried-by-pseudotyped-lentivirus-improves-neuron-survival-and-cognitive-functional-recovery-of-post-ischemia-in-rats
#6
Jia-Yu Cao, Yong Lin, Yan-Fei Han, Sheng-Hao Ding, Yi-Ling Fan, Yao-Hua Pan, Bing Zhao, Qin-Hua Guo, Wen-Hua Sun, Jie-Qing Wan, Xiao-Ping Tong
AIMS: Nerve growth factor (NGF) has been reported to prevent neuronal damage and contributes to the functional recovery in animal brain injury models and human ischemic disease as well. We aimed to investigate a potential therapeutic effect of NGF gene treatment in ischemic stroke and to estimate the functional recovery both at the cellular and cognitive levels in an ischemia rat model. METHODS: After microinjection of pseudolentivirus-delivered β-NGF into an established ischemic stroke model in rats (tMCAO), we estimated neuronal cell apoptosis with TUNEL labeling and neurogenesis by cell proliferation marker Ki67 staining in both ischemic core and penumbra of striatum...
February 6, 2018: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29406402/impaired-cognitive-performance-in-endothelial-nitric-oxide-synthase-knock-out-mice-after-ischemic-stroke-a-pilot-study
#7
Shanshan Li, Yao Wang, Ze Jiang, Yaping Huai, James K Liao, Kaari A Lynch, Ross Zafonte, Lisa J Wood, Qing Mei Wang
OBJECTIVES: Cognitive dysfunction and dementia are common following ischemic stroke. Endothelial nitric oxide synthase (eNOS) has been found to play an important role in neurological function and cognition. The purpose of the present study was to assess the specific role of eNOS in cognitive performance after stroke. DESIGN: Male wildtype (WT) and mice lacking eNOS (eNOS) underwent middle cerebral artery occlusion (MCAO) or sham-surgery. Primary outcomes were repeated measures of neurological score, limb asymmetry, sensory/motor function and spatial memory/learning assessed at intervals up to 28-days post-surgery...
February 5, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29372883/brain-repair-by-hematopoietic-growth-factors-in-the-subacute-phase-of-traumatic-brain-injury
#8
Gentian Toshkezi, Michele Kyle, Sharon L Longo, Lawrence S Chin, Li-Ru Zhao
OBJECTIVE Traumatic brain injury (TBI) is a major cause of long-term disability and death in young adults. The lack of pharmaceutical therapy for post-acute TBI recovery remains a crucial medical challenge. Stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF), which are 2 key hematopoietic growth factors, have shown neuroprotective and neurorestorative effects in experimental stroke. The objective of this study was to determine the therapeutic efficacy of combined treatment (SCF + G-CSF) in subacute TBI...
January 26, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29354984/-electroacupuncture-for-post-stroke-cognitive-impairment-a-systematic-review-and-meta-analyses
#9
Jie Zhan, Xuewen Wang, Nanfang Cheng, Feng Tan
OBJECTIVE: To systematically evaluate the efficacy and safety of electroacupuncture (EA) for post stroke cognitive impairment (PSCI). METHODS: The randomized clinical trials (RCTs) regarding EA for PSCI published before October of 2016 were researched in China National Knowledge Infrastructure (CNKI), Chinese Biomedical Database (CBM), WanFang database, VIP medicine information system, PubMed and Cochrane Library. The literature screening and information extraction was conducted by two independent reviewers...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29354218/evolution-of-short-cognitive-test-performance-in-stroke-patients-with-vascular-cognitive-impairment-and-vascular-dementia-baseline-evaluation-and-follow-up
#10
Nilton Custodio, Rosa Montesinos, David Lira, Eder Herrera-Perez, Yadira Bardales, Lucia Valeriano-Lorenzo
There is limited evidence about the progression of cognitive performance during the post-stroke stage. Objective: To assess the evolution of cognitive performance in stroke patients without vascular cognitive impairment (VCI), patients with vascular mild cognitive impairment (MCI), and patients with vascular dementia (VD). Methods: A prospective cohort of stroke outpatients from two secondary medical centers in Lima, Peru was studied. We performed standardized evaluations at definitive diagnosis (baseline evaluation), and control follow-ups at 6 and 12 months, including a battery of short cognitive tests: Clinical Dementia Rating (CDR), Addenbrooke's Cognitive Examination (ACE), and INECO Frontal Screening (IFS)...
October 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29338817/correlation-of-stress-hyperglycemia-after-ischemic-stroke-with-early-vascular-cognitive-impairment
#11
Yi Dong Zhou, Huai Wu Yuan, Ren Jie Ji, Ben Yan Luo
Objective To investigate the influence and forecast value of stress hyperglycemia on the early vascular cognitive impairment (VCI) in stroke patients.Methods Totally 422 patients with acute non-diabetic stroke were divided into three groups according to the fasting plasma glucose level:the euglycemia group (<6.1 mmol/L),the mild stress hyperglycemia group (6.1-7.0 mmol/L),and the severe stress hyperglycemia group (≥7.0 mmol/L).Mini-mental state examination,Alzheimer's disease rating scale cognitive subscale,and clinical dementia rating scale were used to evaluate early cognition in post-stroke patients,and patients were divided into three groups accordingly:normal cognitive function group,mild VCI group,and vascular dementia group...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29334331/transport-mobility-5%C3%A2-years-after-stroke-in-an-urban-setting
#12
Hanna C Persson, Helena Selander
Background People after stroke may have residual problems with mobility that can affect their independence and mode of transport. However, there is limited knowledge about transport mobility several years after stroke. Objective The objective was to survey the outdoor mobility and transportation in an urban setting five years post-stroke. Method This cross-sectional study was based on a mail survey focusing on long-term consequences after stroke. The survey comprises a set of self-evaluated questionnaires and was sent to 457 persons, of whom 281 responded (61...
January 15, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29325929/post-stroke-cognitive-impairment-depression-and-apathy-untangling-the-relationship
#13
EDITORIAL
Perminder S Sachdev
No abstract text is available yet for this article.
December 11, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29322861/community-mobility-after-stroke-a-systematic-review
#14
Steven Wesselhoff, Timothy A Hanke, Christian C Evans
Background Stroke is the leading cause of severe disability and many survivors report long-term physical or cognitive impairments that may impact their ability to achieve community mobility (CM). PURPOSE: To determine the extent to which people with chronic stroke achieve CM compared to age-matched norms or non-neurologically impaired controls. Methods The StrokEDGE outcome measures were searched to identify validated tools that included >25% of items addressing CM. MEDLINE, CINAHL, Google Scholar, PubMed, PEDro and the Cochrane databases were searched from 2001 to 2015 with the identified outcome measures cross-referenced against search terms related to stroke and CM...
January 11, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29310988/an-updated-diagnostic-approach-to-subtype-definition-of-vascular-parkinsonism-recommendations-from-an-expert-working-group
#15
REVIEW
Ivan Rektor, Nicolaas I Bohnen, Amos D Korczyn, Viktoria Gryb, Hrishikesh Kumar, Milica G Kramberger, Frank-Erik de Leeuw, Zvezdan Pirtošek, Irena Rektorová, Ilana Schlesinger, Jaroslaw Slawek, Peter Valkovič, Branislav Veselý
This expert working group report proposes an updated approach to subtype definition of vascular parkinsonism (VaP) based on a review of the existing literature. The persistent lack of consensus on clear terminology and inconsistent conceptual definition of VaP formed the impetus for the current expert recommendation report. The updated diagnostic approach intends to provide a comprehensive tool for clinical practice. The preamble for this initiative is that VaP can be diagnosed in individual patients with possible prognostic and therapeutic consequences and therefore should be recognized as a clinical entity...
December 29, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29298550/maximising-recovery-from-aphasia-with-central-and-peripheral-agraphia-the-benefit-of-sequential-treatments
#16
Pélagie M Beeson, Chelsea Bayley, Christine Shultz, Kindle Rising
Maximal recovery from acquired language impairment may require progression from one behavioural treatment protocol to the next in order to build upon residual and relearned cognitive-linguistic and sensory-motor processes. We present a five-stage treatment sequence that was initiated at one year post stroke in a woman with acquired impairments of spoken and written language. As is typical of individuals with left perisylvian damage, she demonstrated marked impairment of phonological retrieval and sublexical phonology, but she also faced additional challenges due to impaired letter shape knowledge and visual attention...
January 3, 2018: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29291599/a-2-year-prospective-follow-up-study-of-temporal-changes-associated-with-post-stroke-cognitive-impairment
#17
HyunSoo Oh, JongSuk Park, WhaSook Seo
AIMS: To explore temporal patterns of change in cognitive impairments during the 2 years following stroke and to identify factors that affect these temporal changes. BACKGROUND: Despite the prognostic importance, temporal changes in post-stroke cognitive impairment have not been systematically investigated. DESIGN: A non-experimental, prospective, longitudinal descriptive study design. METHODS: Fifty-two stroke patients were enrolled...
January 1, 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29289546/prediabetes-is-associated-with-post-stroke-cognitive-impairment-in-ischaemic-stroke-patients
#18
Qiongzhang Wang, Kai Zhao, Yan Cai, Xinjie Tu, Yuntao Liu, Jincai He
AIM: Diabetes mellitus is associated with post-stroke cognitive impairment. To the best of our knowledge, no study has explored the relationship between prediabetes and post-stroke cognitive impairment. The purpose of this study is to explore the association between prediabetes and cognitive impairment in ischaemic stroke patients at 1 month. METHODS: Two hundred one acute ischaemic stroke patients were consecutively recruited within the first 24 h after admission and were followed up for 1 month...
December 28, 2017: Brain Research
https://www.readbyqxmd.com/read/29288141/functional-reach-depression-scores-and-number-of-medications-are-associated-with-number-of-falls-in-people-with-chronic-stroke
#19
Aqeel M Alenazi, Mohammed M Alshehri, Shaima Alothman, Jason Rucker, Kari Dunning, Linda D'Silva, Patricia M Kluding
BACKGROUND: Falls are a common adverse event among people with stroke. Previous studies investigating risk of falls after stroke have relied primarily on retrospective fall history ranging from 6-12 months recall, with inconsistent findings. OBJECTIVES: To identify factors and balance assessment tools that are associated with number of falls in individuals with chronic stroke. DESIGN: Secondary analysis of a randomized clinical trial. SETTING: Multisite academic and clinical institutions...
December 26, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29248158/the-role-of-left-insula-in-executive-set-switching-lesion-evidence-from-an-acute-stroke-cohort
#20
Andreja Varjačić, Dante Mantini, Jacob Levenstein, Elitsa D Slavkova, Nele Demeyere, Céline R Gillebert
Impairments in executive functions are common in stroke survivors, both in the acute and in the chronic phase. However, little is known about the underlying lesion neuroanatomy of these deficits. This study aimed to elucidate the pattern of brain damage underlying executive dysfunction in a large and acute stroke cohort. Executive set-switching deficits were evaluated by a shape-based analogue of the Trail Making Test (from the Oxford Cognitive Screen) in a consecutive sample of 144 stroke patients (age: 70 ± 15 years, examination: 5 ± 4 days post-stroke; brain imaging: 1...
November 22, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
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