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Post-stroke cognitive impairment

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https://www.readbyqxmd.com/read/27901591/driving-restrictions-post-stroke-physicians-compliance-with-regulations
#1
Selina Mårdh, Pamela Mårdh, Anna Anund
Objective Suffering a stroke might lead to permanent cognitive and/or physical impairment. It has been shown that these impairments could have an impact on the individual's fitness to drive. In Sweden, as in many other countries, there are regulations on driving cessation post-stroke. The information on driving cessation should be given to all patients and noted in the journal. The present study sought to find out physician's compliance to driving regulations post-stroke as well as follow-up and gender aspects...
November 30, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27899753/temporal-evolution-of-poststroke-cognitive-impairment-using-the-montreal-cognitive-assessment
#2
Britta Nijsse, Johanna M A Visser-Meily, Maria L van Mierlo, Marcel W M Post, Paul L M de Kort, Caroline M van Heugten
BACKGROUND AND PURPOSE: The Montreal Cognitive Assessment (MoCA) is nowadays recommended for the screening of poststroke cognitive impairment. However, little is known about the temporal evolution of MoCA-assessed cognition after stroke. The objective of this study was to examine the temporal pattern of overall and domain-specific cognition at 2 and 6 months after stroke using the MoCA and to identify patient groups at risk for cognitive impairment at 6 months after stroke. METHODS: Prospective cohort study in which 324 patients were administered the MoCA at 2 and 6 months post stroke...
November 29, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27871966/improvement-in-compensation-for-chronic-post-stroke-homonymous-hemianopsia-following-initiation-of-an-ssri-a-case-report
#3
Benjamin A Abramoff, S Byron Milton, Samir R Belagaje
Homonymous hemianopsia (HH) is a common adverse outcome following stroke. Spontaneous improvement more than 6 months post stroke is thought to be unlikely, and traditional visual rehabilitation techniques lack clear evidence of efficacy. The case presented is of a 22 year-old woman who demonstrated improved compensation of her stroke-induced HH following the initiation of a selective serotonin reuptake inhibitor (SSRI). There is evidence supporting the use of SSRIs to improve post-stroke cognitive impairment, motor impairment and depression...
November 18, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27862654/cerebral-small-vessel-disease-medial-temporal-lobe-atrophy-and-cognitive-status-in-patients-with-ischaemic-stroke-and-transient-ischaemic-attack
#4
F Arba, T Quinn, G J Hankey, M Ali, K R Lees, D Inzitari
BACKGROUND AND PURPOSE: Small vessel disease (SVD) and Alzheimer's disease (AD) are two common causes of cognitive impairment and dementia, traditionally considered as distinct processes. The relationship between radiological features suggestive of AD and SVD was explored, and the association of each of these features with cognitive status at 1 year was investigated in patients with stroke or transient ischaemic attack. METHODS: Anonymized data were accessed from the Virtual International Stroke Trials Archive (VISTA)...
November 14, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27859982/transcranial-direct-current-stimulation-effects-on-neural-processing-in-post-stroke-aphasia
#5
Robert Darkow, Andrew Martin, Anna Würtz, Agnes Flöel, Marcus Meinzer
Non-invasive transcranial direct current stimulation (tDCS) can enhance recovery after stroke. However, fundamental knowledge about how tDCS impacts neural processing in the lesioned human brain is currently lacking. In the present study, it was investigated how tDCS modulates brain function in patients with post-stroke language impairment (aphasia). In a cross-over, randomized trial, patients named pictures of common objects during functional magnetic resonance imaging (fMRI). Concurrently, excitatory (anodal-) or sham-tDCS (1 mA, 20 min, or 30 s, respectively) was administered to the left primary motor cortex, a montage with demonstrated potential to improve aphasic language...
November 11, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27836108/post-stroke-cognitive-impairment-a-cross-sectional-comparison-study-between-mild-cognitive-impairment-of-vascular-and-non-vascular-etiology
#6
K P Divya, Ramshekhar N Menon, Ravi Prasad Varma, P N Sylaja, Bejoy Thomas, C Kesavadas, J Sunitha, V S Lekha, S Deepak
PURPOSE: To elucidate the cognitive profiles of post-stroke vascular mild cognitive impairment (VaMCI) in comparison to MCI of non-vascular etiology and cognitively normal healthy controls at a tertiary-care hospital in southern India. RESULTS: Logistic regression analysis adjusted for age and sex comparing VaMCI [N=50] with controls [N=27] revealed significant impairment in visual, verbal learning-recall and executive function scores. As compared to the MCI group [N=36], VaMCI had significantly higher scores on Weschler's Memory Scale (WMS) verbal subset delayed recall scores (p=0...
October 24, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27829011/rehabilitation-profiles-of-older-adult-stroke-survivors-admitted-to-intermediate-care-units-a-multi-centre-study
#7
Laura M Pérez, Marco Inzitari, Terence J Quinn, Joan Montaner, Ricard Gavaldà, Esther Duarte, Laura Coll-Planas, Mercè Cerdà, Sebastià Santaeugenia, Conxita Closa, Miquel Gallofré
BACKGROUND: Stroke is a major cause of disability in older adults, but the evidence around post-acute treatment is limited and heterogeneous. We aimed to identify profiles of older adult stroke survivors admitted to intermediate care geriatric rehabilitation units. METHODS: We performed a cohort study, enrolling stroke survivors aged 65 years or older, admitted to 9 intermediate care units in Catalonia-Spain. To identify potential profiles, we included age, caregiver presence, comorbidity, pre-stroke and post-stroke disability, cognitive impairment and stroke severity in a cluster analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27824877/the-disability-rate-of-5-year-post-stroke-and-its-correlation-factors-a-national-survey-in-china
#8
Yang Yang, Yu-Zhi Shi, Ning Zhang, Shuo Wang, Gabor S Ungvari, Chee H Ng, Yi-Long Wang, Xing-Quan Zhao, Yong-Jun Wang, Chun-Xue Wang, Yu-Tao Xiang
Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors. A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity, depression, cognitive impairment, stroke recurrence and physical disability...
2016: PloS One
https://www.readbyqxmd.com/read/27806718/benefits-of-virtual-reality-based-cognitive-rehabilitation-through-simulated-activities-of-daily-living-a-randomized-controlled-trial-with-stroke-patients
#9
Ana Lúcia Faria, Andreia Andrade, Luísa Soares, Sergi Bermúdez I Badia
BACKGROUND: Stroke is one of the most common causes of acquired disability, leaving numerous adults with cognitive and motor impairments, and affecting patients' capability to live independently. There is substancial evidence on post-stroke cognitive rehabilitation benefits, but its implementation is generally limited by the use of paper-and-pencil methods, insufficient personalization, and suboptimal intensity. Virtual reality tools have shown potential for improving cognitive rehabilitation by supporting carefully personalized, ecologically valid tasks through accessible technologies...
November 2, 2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27804110/cognitive-function-in-stroke-survivors-a-10-year-follow-up-study
#10
H Delavaran, A-C Jönsson, H Lövkvist, S Iwarsson, S Elmståhl, B Norrving, A Lindgren
OBJECTIVES: Post-stroke cognitive impairment (PSCI) has considerable impact on patients and society. However, long-term studies on PSCI are scarce and may be influenced by assessment methods and selection bias. We aimed to (i) assess the prevalence of long-term PSCI; (ii) compare two common cognitive assessment instruments; and (iii) compare cognitive function of long-term stroke survivors with non-stroke persons. METHODS: Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were administered to 10-year survivors from a population-based cohort of first-ever stroke patients included in the Lund Stroke Register, Sweden, in 2001-2002...
November 1, 2016: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27803646/anti-nogo-a-immunotherapy-does-not-alter-hippocampal-neurogenesis-after-stroke-in-adult-rats
#11
Daniel J Shepherd, Shih-Yen Tsai, Timothy E O'Brien, Robert G Farrer, Gwendolyn L Kartje
Ischemic stroke is a leading cause of adult disability, including cognitive impairment. Our laboratory has previously shown that treatment with function-blocking antibodies against the neurite growth inhibitory protein Nogo-A promotes functional recovery after stroke in adult and aged rats, including enhancing spatial memory performance, for which the hippocampus is critically important. Since spatial memory has been linked to hippocampal neurogenesis, we investigated whether anti-Nogo-A treatment increases hippocampal neurogenesis after stroke...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27802359/antihypertensive-withdrawal-for-the-prevention-of-cognitive-decline
#12
REVIEW
Susan Jongstra, Jennifer K Harrison, Terry J Quinn, Edo Richard
BACKGROUND: Clinical trials and observational data have variously shown a protective, harmful or neutral effect of antihypertensives on cognitive function. In theory, withdrawal of antihypertensives could improve cerebral perfusion and reduce or delay cognitive decline. However, it is also plausible that withdrawal of antihypertensives may have a detrimental effect on cognition through increased incidence of stroke or other vascular events. OBJECTIVES: To assess the effects of complete withdrawal of at least one antihypertensive medication on incidence of dementia, cognitive function, blood pressure and other safety outcomes in cognitively intact and cognitive impaired adults...
November 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27802225/urine-formaldehyde-predicts-cognitive-impairment-in-post-stroke-dementia-and%C3%A2-alzheimer-s-disease
#13
Zhiqian Tong, Weishan Wang, Wenhong Luo, Jihui Lv, Hui Li, Hongjun Luo, Jianping Jia, Rongqiao He
Although Alzheimer's disease (AD) was first described over 100 years ago, there is still no suitable biomarker for diagnosing AD in easily collectable samples (e.g., blood plasma, saliva, and urine). Here, we investigated the relationship between morning urine formaldehyde concentration and cognitive impairment in patients with post-stroke dementia (PSD) or AD in this cross-sectional survey for 7 years. Cognitive abilities of the study participants (n = 577, four groups: 231 controls, 61 stroke, 65 PSD, and 220 AD) were assessed by Mini-Mental State Examination (MMSE)...
October 14, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27784823/white-matter-hyperintensity-volume-predicts-persistent-cognitive-impairment-in-transient-ischemic-attack-and-minor-stroke
#14
Leka Sivakumar, Parnian Riaz, Mahesh Kate, Thomas Jeerakathil, Christian Beaulieu, Brian Buck, Richard Camicioli, Ken Butcher
BACKGROUND: Temporary and permanent cognitive changes following transient ischemic attack/minor stroke have been described previously. It is unknown if persisting cognitive deficits in these patients are correlated with acute infarction identified using magnetic resonance imaging. AIMS: We tested the hypothesis that persistent cognitive impairment after transient ischemic attack/minor stroke can be predicted by the volume of diffusion-weighted imaging lesions. METHODS: Acute transient ischemic attack/minor stroke (NIH stroke scale score ≤ 3) patients were prospectively recruited within 72 h of onset...
October 26, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27780506/differences-in-cognitive-profiles-between-traumatic-brain-injury-and-stroke-a-comparison-of-the-montreal-cognitive-assessment-and-mini-mental-state-examination
#15
Hao Zhang, Xiao-Nian Zhang, Hui-Li Zhang, Liang Huang, Qian-Qian Chi, Xin Zhang, Xiao-Ping Yun
PURPOSE: To investigate the profiles of cognitive impairment through Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) in patients with chronic traumatic brain injury (TBI) or stroke and to evaluate the sensitivity of the two scales in patients with TBI. METHODS: In this cohort study, a total of 230 patients were evaluated, including TBI group (n = 103) and stroke group (n = 127). The cognitive functions of two groups were evaluated by designated specialists using MoCA (Beijing version) and MMSE (Chinese version)...
October 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/27767202/quality-of-life-after-paediatric-ischaemic-stroke
#16
Salome Kornfeld, Martina Studer, Stephanie Winkelbeiner, Mária Regényi, Eugen Boltshauser, Maja Steinlin
AIM: Paediatric arterial ischaemic stroke can lead to reduced quality of life (QoL). It is important to identify predictors of QoL to support recovery. We examined long-term QoL after arterial ischaemic stroke concerning different variables. METHOD: Children registered in the Swiss Neuropediatric Stroke Registry and suffering from arterial ischaemic stroke between 2000 and 2008 were included. Two years post-stroke, assessments included intelligence quotient tests for cognitive impairment and modified Rankin Scale (mRS) for neurological impairment; 5 years post-stroke, the Kidscreen-27 was used for QoL, DSM-IV criteria screening was used for attention deficits, and the ABILHAND-Kids was used for manual motor skills...
October 21, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27757933/treating-hypertension-to-prevent-cognitive-decline-and-dementia-re-opening-the-debate
#17
M Florencia Iulita, Hélène Girouard
Hypertension and dementia are two of the most prevalent and damaging diseases associated with aging. Chronic hypertension, particularly during mid-life, is a strong risk factor for late-life cognitive decline and impairment. Hypertension is also the number one risk factor for stroke and a major contributor to the pathogenesis of vascular dementia and Alzheimer's disease. Despite the vast epidemiologic and mechanistic evidence linking hypertension to cognitive impairment, and the positive effects of blood pressure lowering on reducing the risk of post-stroke dementia, uncertainty remains about the benefit of antihypertensive medication on other forms of dementia...
October 19, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27750246/the-course-of-activities-in-daily-living-who-is-at-risk-for-decline-after-first-ever-stroke
#18
Roderick Wondergem, Martijn F Pisters, Eveline J Wouters, Nick Olthof, Rob A de Bie, Johanna M A Visser-Meily, Cindy Veenhof
BACKGROUND: Stroke is not only an acute disease, but for the majority of patients, it also becomes a chronic condition. There is a major concern about the long-term follow-up with respect to activities of daily living (ADL) in stroke survivors. Some patients seem to be at risk for decline after a first-ever stroke. The purpose of this study was to determine the course of ADL from 3 months after the first-ever stroke and onward and identify factors associated with decline in ADL. METHODS: A systematic literature search of 3 electronic databases through June 2015 was conducted...
October 18, 2016: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/27724945/a-robot-based-behavioural-task-to-quantify-impairments-in-rapid-motor-decisions-and-actions-after-stroke
#19
Teige C Bourke, Catherine R Lowrey, Sean P Dukelow, Stephen D Bagg, Kathleen E Norman, Stephen H Scott
BACKGROUND: Stroke can affect our ability to perform daily activities, although it can be difficult to identify the underlying functional impairment(s). Recent theories highlight the importance of sensory feedback in selecting future motor actions. This selection process can involve multiple processes to achieve a behavioural goal, including selective attention, feature/object recognition, and movement inhibition. These functions are often impaired after stroke, but existing clinical measures tend to explore these processes in isolation and without time constraints...
October 10, 2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27714669/a-post-stroke-therapeutic-regimen-with-omega-3-polyunsaturated-fatty-acids-that-promotes-white-matter-integrity-and-beneficial-microglial-responses-after-cerebral-ischemia
#20
Xiaoyan Jiang, Hongjian Pu, Xiaoming Hu, Zhishuo Wei, Dandan Hong, Wenting Zhang, Yanqin Gao, Jun Chen, Yejie Shi
White matter injury induced by ischemic stroke elicits sensorimotor impairments, which can be further deteriorated by persistent proinflammatory responses. We previously reported that delayed and repeated treatments with omega-3 polyunsaturated fatty acids (n-3 PUFAs) improve spatial cognitive functions and hippocampal integrity after ischemic stroke. In the present study, we report a post-stroke n-3 PUFA therapeutic regimen that not only confers protection against neuronal loss in the gray matter but also promotes white matter integrity...
December 2016: Translational Stroke Research
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