Philip R L Parker, Elliott T T Abe, Natalie T Beatie, Emmalyn S P Leonard, Dylan M Martins, Shelby L Sharp, David G Wyrick, Luca Mazzucato, Cristopher M Niell
In natural contexts, sensory processing and motor output are closely coupled, which is reflected in the fact that many brain areas contain both sensory and movement signals. However, standard reductionist paradigms decouple sensory decisions from their natural motor consequences, and head-fixation prevents the natural sensory consequences of self-motion. In particular, movement through the environment provides a number of depth cues beyond stereo vision that are poorly understood. To study the integration of visual processing and motor output in a naturalistic task, we investigated distance estimation in freely moving mice...
September 20, 2022: ELife