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https://www.readbyqxmd.com/read/28210045/a-kinematic-analysis-of-the-lower-limb-with-regard-to-restricted-spinal-motion-during-gait
#1
Hyeon-Nam Song, Young Mi Kim, Kyoung Kim
[Purpose] The purpose of this study was to investigate the effect of restricted spinal motion on kinematic changes in the lower extremities using a rigid thoracolumbosacral orthosis. [Subjects and Methods] Forty healthy males in their 20s were selected as the sample, which was randomly and evenly divided into two groups: (1) the WT group (with a thoracolumbosacral orthosis) and (2) the WOT group (without a thoracolumbosacral orthosis). The spinal orthosis used in this study was a thoracolumbosacral orthosis called a plastic body jacket...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28203549/microbiological-and-clinical-characteristics-of-hypermucoviscous-klebsiella-pneumoniae-isolates-associated-with-invasive-infections-in-china
#2
Yinjuan Guo, Shanshan Wang, Lingling Zhan, Ye Jin, Jingjing Duan, Zhihao Hao, Jingnan Lv, Xiuqin Qi, Liang Chen, Barry N Kreiswirth, Liangxing Wang, Fangyou Yu
A distinctive syndrome caused by hypermucoviscous Klebsiella pneumoniae (HMKP) including pyogenic liver abscess (PLA) is now becoming a globally emerging disease. In the present study, 22.8% (84/369) of K. pneumoniae clinical isolates associated with various types of invasive infections were identified as HMKP, with 45.2% associated with PLA. Multivariate regression analysis showed that male patients with 41-50 years, PLA, diabetes mellitus, and hypertension were independent risk factors for HMKP infections...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28194839/-ge4-bi14-4-a-case-of-element-segregation-on-the-molecular-level
#3
Robert J Wilson, Stefanie Dehnen
Extraction of a solid with the nominal composition "K2 GeBi" with 1,2-diaminoethane (en) in the presence of 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (crypt-222) afforded the salt [K(crypt-222)]4 (Ge4 Bi14 ). The 18-atom Zintl anion (Ge4 Bi14 )(4-) has a heretofore unknown molecular topology, which can be thought of as the formal condensation product of two E11(3-) cages along a shared Ge4 waist. In this way, (Ge4 Bi14 )(4-) represents the largest and most structurally complex Bi-containing polyanion...
February 14, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28192590/tomographic-findings-after-implantation-of-ferrara-intrastromal-corneal-ring-segments-in-keratoconus
#4
João Marcelo Lyra, Daniela Lyra, Guilherme Ribeiro, Leonardo Torquetti, Paulo Ferrara, Aydano Machado
PURPOSE: To analyze and compare changes to the anterior and posterior corneal surfaces after Ferrara intracorneal ring segment (ICRS) (AJL, Boecillo, Spain) implantation and to correlate those changes with visual outcomes. METHODS: This retrospective case series study comprised consecutive patients with keratoconus implanted with the Ferrara ICRS. Computed tomography scans of the two corneal surfaces were obtained preoperatively and postoperatively with a rotating Scheimpflug imaging system...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28182848/simultaneous-determination-of-8-b-vitamins-in-rat-intestinal-perfusate-to-identify-effects-of-osmotic-pressures-on-absorptions
#5
Xiaobo Wang, Jian Xiao, Hui Zhou, Ying Qiu, Hui Peng, Yangyang Sun, Jiwen Zhang, Wei Qian, Lixin Sun
A rapid and accurate HPLC-DAD method was developed and validated to simultaneously determine eight B-vitamins (VBs, namely thiamine, riboflavin, niacinamide, calcium pantothenic, pyridoxine, biotin, folic acid, and cyanocobalamin) and phenolsulfonphthalein in rat intestinal perfusate. Chromatography separation was achieved using an Inertsil ODS-3 column (250 × 4.6 mm i.d., 5 µm) at the temperature of 40 °C. Gradient elution mode was applied at the flow rate of 1.0 mL/min with the mobile phase of acetonitrile-30 mM K2 HPO4 (pH 5...
February 9, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28167266/the-effect-of-mwcnt-treatment-by-h2o2-and-or-uv-on-fulvic-acids-sorption
#6
Bożena Czech
The carbon nanotubes (CNT) present in the wastewater subjected to treatment will possess altered physico-chemical properties. The changed properties will result in the unknown behavior of CNT in the environment after disposal; and it is expected to differ from their pristine analogues. In the present paper the effect of sorption of dissolved organic matter with fulvic acids (FA) as representatives onto UV and/or H2O2 treated CNT was tested. Both kinetics and mechanism of sorption was estimated. The chemical adsorption was a rate limiting step and a pseudo-second order kinetics described the sorption of FA onto UV and/or H2O2 treated CNT...
February 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28162792/synthetic-pot-not-your-grandfather-s-marijuana
#7
REVIEW
Benjamin M Ford, Sherrica Tai, William E Fantegrossi, Paul L Prather
In the early 2000s in Europe and shortly thereafter in the USA, it was reported that 'legal' forms of marijuana were being sold under the name K2 and/or Spice. Active ingredients in K2/Spice products were determined to be synthetic cannabinoids (SCBs), producing psychotropic actions via CB1 cannabinoid receptors, similar to those of Δ(9)-tetrahydrocannabinol (Δ(9)-THC), the primary active constituent in marijuana. Often abused by adolescents and military personnel to elude detection in drug tests due to their lack of structural similarity to Δ(9)-THC, SCBs are falsely marketed as safe marijuana substitutes...
January 27, 2017: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/28151978/development-and-evaluation-of-up-converting-phosphor-technology-based-lateral-flow-assay-for-quantitative-detection-of-nt-probnp-in-blood
#8
Xiaoli Yang, Liping Liu, Qingfang Hao, Deyong Zou, Xiaoli Zhang, Liping Zhang, Hongmei Li, Yong Qiao, Huansheng Zhao, Lei Zhou
A newly assay, up-converting phosphor technology-based lateral flow (UPT-LF) assay, was developed for rapid and quantitative detection of N-terminal fragment of B-type natriuretic peptide precursor (NT-proBNP), one of the most important serum molecular maker of heat failure, in plasma samples as a point of care testing (POCT) method for diagnosis of acute heart failure. Human plasma from 197 patients with acute heart failure and 200 healthy controls was assessed using the UPT-LF assay, in a comparison with a Roche Elecsys assay...
2017: PloS One
https://www.readbyqxmd.com/read/28139074/synthesis-and-photoluminescence-properties-of-red-emitting-phosphor-la2-x-eux-li0-5-al0-5-o4-x%C3%A2-%C3%A2-0-2-2-with-k2-nif4-structure
#9
S Kasturi, S Satish Kumar, V Sivakumar
Europium (Eu)(3+) -substituted La2 Li0.5 Al0.5 O4 red emitting phosphors were prepared by a conventional high-temperature solid-state reaction method. Powder X-ray diffraction, diffuse reflectance spectra and spectrofluorometry were used as vital characterizing tools for the phosphors. The Eu concentration dependence luminescence properties and Judd-Ofelt intensity parameters were investigated and calculated, respectively. All compositions showed an orange red emission (due to the magnetic and electric dipole transitions of the Eu(3+) ion) with the appropriate Commission Internationale de l'Eclairage (CIE) colour gamut under near ultraviolet or blue ray light excitation...
January 31, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28138001/multiparametric-magnetic-resonance-imaging-for-prediction-of-parenchymal-hemorrhage-in-acute-ischemic-stroke-after-reperfusion-therapy
#10
Kambiz Nael, James R Knitter, Reza Jahan, Jeffery Gornbein, Zahra Ajani, Lei Feng, Brett C Meyer, Lee H Schwamm, Albert J Yoo, Randolph S Marshall, Philip M Meyers, Dileep R Yavagal, Max Wintermark, David S Liebeskind, Judy Guzy, Sidney Starkman, Jeffrey L Saver, Chelsea S Kidwell
BACKGROUND AND PURPOSE: Patients with acute ischemic stroke are at increased risk of developing parenchymal hemorrhage (PH), particularly in the setting of reperfusion therapies. We have developed a predictive model to examine the risk of PH using combined magnetic resonance perfusion and diffusion parameters, including cerebral blood volume (CBV), apparent diffusion coefficient, and microvascular permeability (K2). METHODS: Voxel-based values of CBV, K2, and apparent diffusion coefficient from the ischemic core were obtained using pretreatment magnetic resonance imaging data from patients enrolled in the MR RESCUE clinical trial (Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy)...
January 30, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28133791/the-effect-of-different-protease-inhibitors-on-stability-of-parathyroid-hormone-insulin-and-prolactin-levels-under-different-lag-times-and-storage-conditions-until-analysis
#11
Ozgur Baykan, Ali Yaman, Fethullah Gerin, Onder Sirikci, Goncagul Haklar
INTRODUCTION: Proteolytic cleavage through proteases affects peptide hormone levels, which is of particular significance when the time interval between sampling and analysis is prolonged. We evaluated the stability of parathyroid hormone, insulin, and prolactin molecules (i) with different protease inhibitors such as K2 EDTA, aprotinin, and protease inhibitor cocktail (PIC), (ii) with different lag times (6-72 hours), and (iii) under different storage temperatures (4°C vs room temperature [RT]) until analysis...
January 30, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28130552/melatonin-micronutrients-osteopenia-treatment-study-mots-a-translational-study-assessing-melatonin-strontium-citrate-vitamin-d3-and-vitamin-k2-mk7-on-bone-density-bone-marker-turnover-and-health-related-quality-of-life-in-postmenopausal-osteopenic-women-following
#12
Sifat Maria, Mark H Swanson, Larry T Enderby, Frank D'Amico, Brianna Enderby, Rebekah M Samsonraj, Amel Dudakovic, Andre J van Wijnen, Paula A Witt-Enderby
This one-year double blind randomized control trial assessed the effects of nightly melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7; MSDK) on bone mineral density (BMD) and quality of life (QOL) in postmenopausal osteopenic women (ages 49-75). Compared to placebo, MSDK treatment increased BMD in lumbar spine (4.3%) and left femoral neck (2.2%), with an upward trend for total left hip (p=0.069). MSDK increased serum P1NP levels and reduced bone turnover (CTx:P1NP). Psychometric analyses indicated that mood and sleep quality improved for the MSDK group...
January 26, 2017: Aging
https://www.readbyqxmd.com/read/28128384/mung-bean-phaseolus-radiatus-l-polyphenol-extract-attenuates-aluminum-induced-cardiotoxicity-through-an-ros-triggered-ca-2-jnk-nf-%C3%AE%C2%BAb-signaling-pathway-in-rats
#13
Dai Cheng, Ruhua Wang, Chunling Wang, Lihua Hou
Aluminum (Al) has been linked to the development of some cardiovascular diseases and mung bean is a functional food with the ability to detoxify. We aimed to evaluate the preventive effect and possible underlying mechanisms of the mung bean polyphenol extract (MPE) on Al-induced cardiotoxicity. Control, AlCl3 (171.8 mg Al per kg body weight), MPE + AlCl3 (Al-treatment plus 200 mg MPE per kg body weight), and a group of MPE per se were used. Al intake induced a significant increase of serum CK and LDH activity and the level of Na(+), Ca(2+), malondialdehyde and advanced oxidation protein products in the AlCl3-treated rats' heart tissue...
January 27, 2017: Food & Function
https://www.readbyqxmd.com/read/28127087/neptune-s-dynamic-atmosphere-from-kepler-k2-observations-implications-for-brown-dwarf-light-curve-analyses
#14
Amy A Simon, Jason F Rowe, Patrick Gaulme, Heidi B Hammel, Sarah L Casewell, Jonathan J Fortney, John E Gizis, Jack J Lissauer, Raul Morales-Juberias, Glenn S Orton, Michael H Wong, Mark S Marley
Observations of Neptune with the Kepler Space Telescope yield a 49 day light curve with 98% coverage at a 1 minute cadence. A significant signature in the light curve comes from discrete cloud features. We compare results extracted from the light curve data with contemporaneous disk-resolved imaging of Neptune from the Keck 10-m telescope at 1.65 microns and Hubble Space Telescope visible imaging acquired nine months later. This direct comparison validates the feature latitudes assigned to the K2 light curve periods based on Neptune's zonal wind profile, and confirms observed cloud feature variability...
February 1, 2016: Astrophysical Journal
https://www.readbyqxmd.com/read/28122278/detailed-nmr-investigation-of-cyclodextrin-perfluorinated-surfactant-interactions-in-aqueous-media
#15
Mary Jo Weiss-Errico, Kevin E O'Shea
Perfluorochemicals (PFCs) are contaminants of serious concern because of their toxicological properties, widespread presence in drinking water sources, and incredible stability in the environment. To assess the potential application of α-, β-, and γ-cyclodextrins for PFC remediation, we investigated their complexation with linear fluorinated carboxylic acids, sulfonates, and a sulfonamide with carbon backbones ranging from C4-C9. (19)F Nuclear Magnetic Resonance (NMR) spectroscopy studies demonstrated β-CD formed the strongest complexes with these PFCs...
January 16, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28111921/glyphosate-sorption-desorption-on-biochars-interactions-of-physical-and-chemical-processes
#16
Kathleen E Hall, Kurt A Spokas, Beatriz Gamiz, Lucia Cox, Sharon K Papiernik, William C Koskinen
BACKGROUND: Biochar, a carbon-rich product of biomass pyrolysis, could limit glyphosate transport in soil and remediate contaminated water. The present study investigates the sorption/desorption behavior of glyphosate on biochars prepared from different hardwoods at temperatures ranging from 350°C to 900°C to elucidate fundamental mechanisms. RESULTS: Glyphosate (1 mg L(-1) ) sorption on biochars increased with pyrolysis temperature and was highest on 900°C biochars; however, total sorption was low on a mass basis (<0...
January 23, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28111326/molecular-characterisations-of-integrons-in-clinical-isolates-of-klebsiella-pneumoniae-in-a-chinese-tertiary-hospital
#17
Xuan Xu, Xuan Li, Mei Luo, Pin Liu, Kewen Su, Ying Qing, Shuai Chen, Jingfu Qiu, Yingli Li
BACKGROUND: Integrons are mobile genetic elements that play an important role in the distribution of antibiotic-resistance genes among bacteria. This study aimed to investigate the distribution of integrons in clinical isolates of Klebsiella pneumoniae and explore the molecular mechanism of integron-mediated multiple-drug resistance in K. pneumoniae. METHODS: Class 1, 2, and 3 integrases were identified by polymerase chain reaction (PCR) among 178 K. pneumoniae clinical isolates...
January 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28108554/genome-wide-analysis-of-lncrna-and-mrna-expression-during-differentiation-of-abdominal-preadipocytes-in-the-chicken
#18
Tao Zhang, Xiangqian Zhang, Kunpeng Han, Genxi Zhang, Jinyu Wang, Kaizhou Xie, Qian Xue
Long non-coding RNAs (lncRNAs) regulate adipogenesis and other processes associated with metabolic tissue development and function. However, little is known about the function and profile of lncRNAs during preadipocyte differentiation in the chicken (Gallus gallus). Herein, lncRNA and mRNA expression in preadipocytes at different stages of differentiation were analyzed using RNA sequencing. A total of 1,300,074,528 clean reads and 27,023 novel lncRNAs were obtained from 12 samples. The number of genes (1,336 lncRNAs and 1,759 mRNAs; 3,095 in total) differentially expressed across various stages declined as differentiation progressed...
January 20, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28107947/surface-enhanced-raman-spectroscopy-sers-as-a-method-for-the-toxicological-analysis-of-synthetic-cannabinoids
#19
Thaddeus Mostowtt, Bruce McCord
Synthetic cannabinoids (K2, spice) present problems in forensic investigations because standard presumptive methods, such as immunoassays, are insufficiently specific for the wide range of potential target compounds. This issue can lead to problems with low sensitivity and yield false negative results. A potential solution to this problem is surface enhanced Raman spectroscopy (SERS). In this study we demonstrate the analysis of a set of structurally similar synthetic cannabinoids using SERS. The procedure involves mixing the analyte with gold nanoparticles prepared in a solution containing alkali or alkaline earth salt solutions...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107005/kinetic-analysis-and-mechanism-of-the-hydrolytic-degradation-of-squaramides-and-squaramic-acids
#20
Marta Ximenis, Emilio Bustelo, Andrés G Algarra, Manel Vega, Carmen Rotger, Manuel G Basallote, Antonio Costa
The hydrolytic degradation of squaramides and squaramic acids, the product of partial hydrolysis of squaramides, has been evaluated by UV spectroscopy at 37 °C in the pH range 3-10. Under these conditions, the compounds are kinetically stable over long time periods (>100 days). At pH >10, the hydrolysis of the squaramate anions shows first-order dependence on both squaramate and OH(-). At the same temperature and [OH(-)], the hydrolysis of squaramides usually displays biphasic spectral changes (A → B → C kinetic model) with formation of squaramates as detectable reaction intermediates...
February 3, 2017: Journal of Organic Chemistry
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