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case record of the massachusetts case 33 -2015

Anil Can, Robert F Rudy, Victor M Castro, Dmitriy Dligach, Sean Finan, Sheng Yu, Vivian Gainer, Nancy A Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T Weiss, Rose Du
BACKGROUND AND PURPOSE: Both low serum calcium and magnesium levels have been associated with the extent of bleeding in patients with intracerebral hemorrhage, suggesting hypocalcemia- and hypomagnesemia-induced coagulopathy as a possible underlying mechanism. We hypothesized that serum albumin-corrected total calcium and magnesium levels are associated with ruptured intracranial aneurysms. METHODS: The medical records of 4701 patients, including 1201 prospective patients, diagnosed at the Brigham and Women's Hospital and Massachusetts General Hospital between 1990 and 2016 were reviewed and analyzed...
May 29, 2018: Stroke; a Journal of Cerebral Circulation
Curtis R Heberle, Amir-Houshang Omidvari, Ayman Ali, Sonja Kroep, Chung Yin Kong, John M Inadomi, Joel H Rubenstein, Angela C Tramontano, Emily C Dowling, William D Hazelton, E Georg Luebeck, Iris Lansdorp-Vogelaar, Chin Hur
BACKGROUND & AIMS: It is important to identify patients with Barrett's esophagus (BE), the precursor to esophageal adenocarcinoma (EAC). Patients with BE usually are identified by endoscopy, which is expensive. The Cytosponge, which collects tissue from the esophagus noninvasively, could be a cost-effective tool for screening individuals with gastroesophageal reflux disease (GERD) who are at increased risk for BE. We developed a model to analyze the cost effectiveness of using the Cytosponge in first-line screening of patients with GERD for BE with endoscopic confirmation, compared with endoscopy screening only...
September 2017: Clinical Gastroenterology and Hepatology
Nazanin Ebrahimiadib, Bobeck S Modjtahedi, Samaneh Davoudi, C Stephen Foster
PURPOSE: To evaluate the efficacy of chlorambucil in the treatment of serpiginous choroiditis. METHODS: Patient records from the Massachusetts Eye Research and Surgery Institution (MERSI) were reviewed from over the past 10 years. In total, 17 patients with the diagnosis of serpiginous choroiditis treated with chlorambucil were identified. QuantiFERON gold was negative in all of them. Chlorambucil was started at 0.15 mg/kg and dosage was titrated up using weekly white blood cell (WBC) count to achieve a target cell number of 3...
2018: Ocular Immunology and Inflammation
Jessica A Zeidman, Paul C Shellito, Benjamin T Davis, Lawrence R Zukerberg
Presentation of Case. Dr. Robert H. Goldstein (Medicine): A 33-year-old man was seen in the surgery clinic of this hospital because of painful bowel movements and rectal bleeding. The patient had been well until approximately 4 months before this presentation, when pain with defecation developed...
August 18, 2016: New England Journal of Medicine
Marie-Claude Robert, Nour Khreim, Amit Todani, Samir A Melki
AIM: To characterise the emergence pattern of cavitation bubbles into the anterior chamber (AC) following femtosecond laser-assisted in situ keratomileusis (LASIK)-flap creation METHODS: Retrospective review of patients undergoing femtosecond LASIK surgery at Boston Laser, a private refractive surgery practice in Boston, Massachusetts, between December 2008 and February 2014. Patient charts were reviewed to identify all cases with gas bubble migration into the AC...
September 2015: British Journal of Ophthalmology
Edwin Choy, Eyal C Attar, Kevin S Oh, Ambrose J Huang, Darcy A Kerr
Presentation of Case. Nurse Practitioner Mark S. Brezina (Hematology): A 60-year-old man was seen in the outpatient cancer center at this hospital because of bone pain and skeletal lesions on imaging. The patient had been well until approximately 2 months before this evaluation, when he had a..
October 23, 2014: New England Journal of Medicine
Kelly K Ferguson, Thomas F McElrath, Yi-An Ko, Bhramar Mukherjee, John D Meeker
BACKGROUND: Preterm birth is a significant public health problem, affecting over 1 in 10 live births and contributing largely to infant mortality and morbidity. Everyday exposure to environmental chemicals such as phthalates could contribute to prematurity, and may be modifiable. In the present study we examine variability in phthalate exposure across gestation and identify windows of susceptibility for the relationship with preterm birth. METHODS: Women were recruited early in pregnancy as part of a prospective, longitudinal birth cohort at the Brigham and Women's Hospital in Boston, Massachusetts...
September 2014: Environment International
Stephanie Dukhovny, Louise Wilkins-Haug, Thomas D Shipp, Carol B Benson, Anjali J Kaimal, Rosemary Reiss
OBJECTIVES: Our purpose was to review the outcomes of singleton pregnancies in which an absent nasal bone was noted on first- or second-trimester sonography and aneuploidy was not present. METHODS: We identified singleton pregnancies from 2005 to 2011 in which an absent nasal bone was noted on sonography, aneuploidy was excluded, and newborn examinations were available for review. Sonographic reports were reviewed for anomalies, growth, and amniotic fluid volume...
December 2013: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Feyza Marouf, Cosmas C Giallourakis, Lee Baer, Michael S Hanau, Barbara C Holbert
Presentation of Case. Dr. Justin Chen (Psychiatry): A 40-year-old woman was seen in the emergency department at this hospital because of abdominal pain, nausea, anorexia, and weight loss, and she said, "I think I have pancreatic cancer." The patient was in her usual health until approximately 15..
October 24, 2013: New England Journal of Medicine
Britta Brueckmann, Jose L Villa-Uribe, Brian T Bateman, Martina Grosse-Sundrup, Dean R Hess, Christopher L Schlett, Matthias Eikermann
BACKGROUND: Postoperative respiratory failure is associated with increased morbidity and mortality, as well as high costs of hospital care. METHODS: Using electronic anesthesia records, billing data, and chart review, the authors developed and validated a score predicting reintubation in the hospital after primary extubation in the operating room, leading to unplanned mechanical ventilation within the first 3 postoperative days. Using multivariable logistic regression analysis, independent predictors were determined and a score postulated and validated...
June 2013: Anesthesiology
Sejal Chowdhary, Bolanle Bukoye, Arjun M Bhansali, Alexander R Carbo, May Adra, Sheila Barnett, Mark D Aronson, Daniel A Leffler
IMPORTANCE: Methemoglobinemia is a rare but serious disorder, defined as an increase in oxidized hemoglobin resulting in a reduction of oxygen-carrying capacity. Although methemoglobinemia is a known complication of topical anesthetic use, few data exist on the incidence of and risk factors for this potentially life-threatening disorder. OBJECTIVE: To examine the incidence of and risk factors for procedure-related methemoglobinemia to identify patient populations at high risk for this complication...
May 13, 2013: JAMA Internal Medicine
J Carl Pallais, Michael A Blake, Vikram Deshpande
Presentation of Case. Dr. Kimberly G. Blumenthal (Medicine): A 34-year-old woman, 2.5 months post partum, was admitted to this hospital because of episodes of altered mental status. The patient had been well until approximately 3 months before admission, near the end of her pregnancy, when periodic..
October 25, 2012: New England Journal of Medicine
Angela V Turalba, Ankoor S Shah, Michael T Andreoli, Christopher M Andreoli, Douglas J Rhee
PURPOSE: Evaluate predictors and outcomes of ocular hypertension after open-globe injury. PATIENTS AND METHODS: This is a retrospective, case-control study reviewing records of consecutive patients with open-globe injuries treated at Massachusetts Eye and Ear Infirmary between February 1999 and January 2007. Of 658 patients treated, 382 had at least 2 months of follow-up and sufficient data to be included. Main outcome measures are visual acuity, intraocular pressure (IOP), and type of glaucoma intervention employed...
January 2014: Journal of Glaucoma
Ana A Weil, Elinor L Baron, Catherine M Brown, Mark S Drapkin
OBJECTIVE: To describe clinical findings and the use of a tick-associated pathogen panel in a series of patients with human granulocytic anaplasmosis (HGA) at a suburban Boston hospital. PATIENTS AND METHODS: Medical records were reviewed for inpatients and outpatients at Newton-Wellesley Hospital with a positive polymerase chain reaction (PCR) result for Anaplasma phagocytophilum during the study period March 1 through November 30, 2009. A PCR panel was used to test for tick-borne pathogens...
March 2012: Mayo Clinic Proceedings
David E Soper, Susanna I Lee, Ji Yeon Kim, Anna G McDonald
Presentation of Case. Dr. Edwin C. Huang (Obstetrics and Gynecology): A 33-year-old woman was admitted to the intensive care unit (ICU) at this hospital 16.5 hours post partum because of leukocytosis and gram-positive rods in the blood. The patient had received routine prenatal care at this..
November 17, 2011: New England Journal of Medicine
Clemens Bergwitz, Michael T Collins, Ravi S Kamath, Andrew E Rosenberg
Presentation of Case. Dr. Eric Hesse (Harvard School of Dental Medicine): A 56-year-old man was seen in the outpatient endocrinology and oral-surgery clinics of this hospital because of recurrent hypophosphatemia. The patient had been well until 19 years earlier, when rib pain developed and a left..
October 27, 2011: New England Journal of Medicine
Lucy H Young, Hasan Bazari, Marlene L Durand, John A Branda
Presentation of Case. Dr. Meghan E. Sise (Medicine): A 22-year-old woman was admitted to this hospital because of blurred vision and renal failure. The patient had been well until 1 week before admission, when she noted blurred vision in her right eye. The next day, she met with her primary care..
October 28, 2010: New England Journal of Medicine
Marc A de Moya, Marcela G del Carmen, Rae M Allain, Ronald E Hirschberg, Jo-Anne O Shepard, Richard L Kradin
Presentation of Case. Dr. Claudius H.O. Conrad (Surgery): A 35-year-old woman was transferred to this hospital because of abdominal pain, fever, and hypotension. Three days earlier, an elective cesarean section was performed at another hospital through a transverse incision of the lower uterine..
October 22, 2009: New England Journal of Medicine
J M Buscaglia, K B Dunbar, P I Okolo, J Judah, P A Akerman, D Cantero, P V Draganov
BACKGROUND AND AIM: Indications for small-bowel enteroscopy are increasing, but advancing the endoscope to the ileum remains challenging, especially for less experienced operators. The aim was to evaluate the ease of use, safety, and efficacy of the Discovery SB overtube (Spirus Medical, Stoughton, Massachusetts, USA) during SB enteroscopy by physicians with no experience of the device. PATIENTS AND METHODS: Thirty-three "untrained" endoscopists performed spiral enteroscopy during one of four 2-day training modules...
March 2009: Endoscopy
Charles M Wiener, Victorine V Muse, Eugene J Mark
Presentation of Case. Dr. Andrew Tinsley (Medicine): A 63-year-old woman was admitted to this hospital because of dyspnea on exertion. The patient had been in her usual state of health until approximately 3 weeks before admission, when dyspnea developed. Approximately 1 week later, she began to..
October 23, 2008: New England Journal of Medicine
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