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https://www.readbyqxmd.com/read/27923112/the-double-mandibular-osteotomy-for-vascular-and-tumor-surgery-of-the-parapharyngeal-space
#1
Thomas Schlieve, Eric R Carlson, Michael Freeman, Ryan Buckley, Josh Arnold
PURPOSE: The purposes of this study are to describe our experience using a double mandibular osteotomy for access to the parapharyngeal space in vascular and tumor surgery and to report on the outcomes and complications of this procedure. PATIENTS AND METHODS: We designed and implemented a case series to review the medical records of all patients treated with a double mandibular osteotomy for parapharyngeal space access from 1994 to 2016. Patient demographic characteristics, indications for the procedure, outcomes, and complications were recorded...
November 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27902883/metastatic-carotid-body-paraganglioma-of-lungs-and-lymph-nodes-unsuspected-diagnosis-on-ebus-tbna
#2
Kalpana Kumari, Deepali Jain, Rohit Kumar, Anant Mohan, Rakesh Kumar
Paragangliomas are tumors that originate from the extra-adrenal chromaffin and nonchromaffin cells of neural crest origin. Lymph node metastases are common, while distant metastases to lung, liver, and bone are rare events and usually occur in the presence of a long standing clinically evident primary tumor. Primary diagnosis of paraganglioma at a metastatic site without a known primary is a diagnostic challenge. We report a case of an adult woman with incidentally detected metastasis to bilateral lungs from an occult carotid body paraganglioma, which presented a cytopathological diagnostic dilemma on EBUS-TBNA from paratracheal lymph nodes...
November 30, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27887852/morphological-and-functional-imaging-of-neck-paragangliomas
#3
J-P Guichard, N Fakhry, J Franc, P Herman, C-A Righini, D Taieb
OBJECTIVE: To review the optimal techniques for localization and characterization of neck paragangliomas (PGL). MATERIAL AND METHODS: Systematic review of the literature from the PubMed/Medline database. RESULTS: Neck PGL are hypervascular tumours essentially arising from paraganglionic tissue situated at the carotid bifurcation (carotid body) and along the vagus nerve. Morphological and functional imaging are indicated to confirm the diagnosis, identify multifocal disease and for local and regional staging...
November 22, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/27871494/current-surgical-management-of-carotid-body-tumors
#4
Victor J Davila, James M Chang, William M Stone, Richard J Fowl, Thomas C Bower, Michael L Hinni, Samuel R Money
BACKGROUND: Carotid body tumors (CBTs) are rare. Management guidelines may include genetic testing for succinate dehydrogenase (SDH) mutations. We performed an institutional review of the surgical management of CBT. METHODS: A retrospective analysis (1994-2015) of CBT excisions at our institution was performed. Data obtained included demographics, genetic testing (if performed), intraoperative details, postoperative morbidity, and long-term outcomes. Data from the first CBT excision were included in patients with bilateral tumors...
December 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27867439/evaluation-of-head-and-neck-paragangliomas-by-computed-tomography-in-patients-with-pheochromocytoma-paraganglioma-syndromes
#5
Ilona Michałowska, Anna Lewczuk, Jarosław Ćwikła, Aleksander Prejbisz, Urszula Swoboda-Rydz, Mariusz I Furmanek, Małgorzata Szperl, Andrzej Januszewicz, Mariola Pęczkowska
BACKGROUND: Hereditary head and neck paragangliomas (HNP) are very often associated with pheochromocytoma-paraganglioma syndromes, which are caused by mutations in genes encoding subunits of succinate dehydrogenase (SDHx) complex. The aim of this study was to determine the frequency and location of HNP among SDHx carriers. MATERIAL/METHODS: A total of 72 patients with SDHx mutations underwent computed tomography examinations of the head and neck. HNP were present in 44 (61...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27858099/-percutaneous-embolization-and-ultrasound-scissors-for-removal-of-a-carotid-body-tumor
#6
I I Venara-Vulpe, B Morisod, G B Morand, J-B Zerlauth, C Simon
Paragangliomas are highly vascularized usually benign neoplasms originating from the sympathoadrenal and parasympathetic paraganglia of the autonomic nervous system. When resectable, the management of these tumors consists of surgical ablation preceded by transarterial embolization. The aim of this article is to describe a novel treatment strategy combining intralesional percutaneous embolization with dissection using ultrasound scissors. The case of a 74-year-old women presenting with a Shamblin type III carotid body paraganglioma is presented...
December 2016: HNO
https://www.readbyqxmd.com/read/27833982/an-evaluation-on-multidisciplinary-management-of-carotid-body-paragangliomas-a-report-of-seven-cases
#7
Dragoş Cătălin Jianu, Silviana Nina Jianu, Andrei Gheorghe Marius Motoc, Traian Flavius Dan, Mărioara Poenaru, Sorina Tăban, Octavian Marius CreŢu
Carotid body paragangliomas (CBPGLs) are a rare neoplasms of the neuroendocrine system that affect the carotid glomus. The aim of this study is to improve their management in our Departments. This retrospective analysis reports family history, clinical presentation, imaging diagnostics, Shamblin classification, surgical treatment, complications, and the outcome of seven patients with CBPGLs. All lesions were represented by a painless cervical mass, with no functional or bilateral neck tumors. One patient had two different localizations (the second one was a glomus tumor of the right prelachrymal sac), and a family history for CBPGL...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27556663/treatment-of-head-and-neck-paragangliomas
#8
Kenneth Hu, Mark S Persky
BACKGROUND: Commonly occurring in the head and neck, paragangliomas are typically benign, highly vascular neoplasms embryologically originating from the extra-adrenal paraganglia of the neural crest. Frequently, these tumors are associated with the vagus or tympanic plexus nerve or the carotid artery, or jugular bulb. Their clinical presentation can vary across a wide spectrum of signs and symptoms. METHODS: We reviewed and compared standard treatment approaches for paragangliomas of the head and neck...
July 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27402879/parent-of-origin-tumourigenesis-is-mediated-by-an-essential-imprinted-modifier-in-sdhd-linked-paragangliomas-slc22a18-and-cdkn1c-are-candidate-tumour-modifiers
#9
Attje S Hoekstra, Ruben D Addie, Cor Ras, Reza M Seifar, Claudia A Ruivenkamp, Inge H Briaire-de Bruijn, Frederik J Hes, Jeroen C Jansen, Eleonora P M Corssmit, Willem E Corver, Hans Morreau, Judith V M G Bovée, Jean-Pierre Bayley, Peter Devilee
Mutations in SDHD and SDHAF2 (both located on chromosome 11) give rise to hereditary paraganglioma almost exclusively after paternal transmission of the mutation, and tumours often show loss of the entire maternal copy of chromosome 11. The 'Hensen' model postulates that a tumour modifier gene located on chromosome 11p15, a region known to harbour a cluster of imprinted genes, is essential to tumour formation. We observed decreased protein expression of the 11p15 candidate genes CDKN1C, SLC22A18 and ZNF215 evaluated in 60 SDHD-mutated tumours compared to normal carotid body tissue and non-SDH mutant tumours...
July 8, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27376229/sympathetic-chain-schwannoma-resembling-carotid-body-tumour
#10
Tallat Najeeb, Musaddiq Khan
Schwannomas are rare, benign nerve sheath tumours of parapharyngeal space. Differential diagnosis should include salivary gland tumours, paragangliomas, neurofibromas, and metastatic lymph nodes. The tumours may arise from vagus nerve and cervical sympathetic chain (CSC). Diagnosis is usually made by imaging techniques: contrast CT, magnetic resonance imaging (MRI), and magnetic resonance angiography (MRA). Fine needle aspiration cytology (FNAC) is useful diagnostic procedure but poor results are seen in neurogenic tumours...
June 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27371607/mediastinal-paraganglioma-fed-by-the-left-circumflex-artery
#11
José María González-Santos, María Elena Arnáiz-García, Ángel Muñoz-Herrera, Javier López-Rodríguez
A 60-year-old male patient who previously underwent carotid and jugular paraganglioma resections was referred because of a mediastinal recurrence at the root of the great vessels. Coronary angiography confirmed the circumflex artery of the left coronary artery as the feeding artery of the tumour. The patient underwent surgery due to the tumour's location and malignant potential. Upon mass resection, histopathological examination characterized the tumour as a secondary paraganglioma. Neuroendocrine tumours arising from chromaffin tissues at the extra-adrenal paraganglions of the autonomic nervous system are termed paragangliomas...
November 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27355479/-percutaneous-phil%C3%A2-embolization-for-preoperative-therapy-of-carotid-body-paragangliomas
#12
G Psychogios, A Berlis, B Märkl, T Schaller, M N Psychogios, J Zenk
Introduction: Paragangliomas are rare tumors representing a therapeutic challenge. In particular, the surgical removal may lead to life-threatening bleeding. The preoperative percutaneous embolization is an alternative that allows a high closure rate of tumor-feeding vessels in a short intervention time and thus significantly reduces intraoperative bleeding probability. Complete tumor resection is facilitated thereby. The use of a new non-adhesive liquid embolic agent is presented here. Methods: A 50-year old patient presented with 4 cm large paraganglioma of the carotid body (Shamblin II)...
June 29, 2016: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27355478/-management-of-complex-tympanojugular-paragangliomas
#13
A Harati, R Schultheiß, K Harati, S Rohde, W Weber, T Deitmer
Background: Tympanojugular paraganglioma (TJP) are benign, high vascularized, local destructive tumors. Despite many studies in the literature, the management of particularly complex TJP (e. g., posterior fossa and/or carotid artery invasion) remains controversial. In the current study we present our treatment strategies for complex TJP and long-term results. Patients and methods: Between 2003 and 2013, 17 patients with TJP Fisch types C and D were treated in our institution. Primary symptoms were hearing loss, followed by facial nerve palsy and lower cranial nerve impairments...
June 29, 2016: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27316787/color-doppler-ultrasound-in-diagnosis-and-assessment-of-carotid-body-tumors-comparison-with-computed-tomography-angiography
#14
Zhan-Qiang Jin, Wen He, Dong-Fang Wu, Mei-Ying Lin, Hua-Tang Jiang
A carotid body tumor (CBT) is a rare, non-chromaffin paraganglioma, and its diagnosis mainly depends on imaging modalities. The aim of this study was to investigate the ability of color Doppler ultrasound (CDU) in the diagnosis and assessment of CBT based on computed tomography (CT). We retrospectively reviewed the CDU and CT features of 49 consecutive CBTs and 23 schwannomas from 67 patients and compared these findings with surgical resection specimens. The mean size of CBT lesions on ultrasound scans and CT angiography (CTA) was 3...
September 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27298550/surgical-excision-of-carotid-body-tumor-through-modified-approach-a-case-report
#15
Sureshkannan Prabakaran, Anand Shankar Subburayulu, P T Ravikumar
Paragangliomas arising from the carotid body in the carotid bifurcation are termed as carotid body tumors. They are usually slow growing and asymptomatic. Considering the anatomical location, invasion or pressure on the adjacent vascular and neural tissues, the importance of early diagnosis and management is critical. In this article a case of carotid body tumor excised through transverse neck skin crease incision is presented along with literature review on the diagnosis, grading and different surgical approaches...
June 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27297087/neurovascular-complications-following-carotid-body-paraganglioma-resection
#16
E Lamblin, I Atallah, E Reyt, S Schmerber, J-L Magne, C A Righini
OBJECTIVE: The present consecutive case series reports our experience in the management of carotid body paraganglioma and aims to assess whether the Shamblin classification or tumor size are predictive of early and late postoperative neurovascular complications. MATERIAL AND METHODS: A retrospective study included 54 carotid body tumor resections in 49 patients, between 1980 and 2011. Data comprised early (<1month) and late (18 months) postoperative neurovascular complications...
June 10, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/27267025/managing-vascular-tumors-open-approaches
#17
REVIEW
Cecelia E Schmalbach, Christine Gourin
The most common vascular tumors encountered by the otolaryngologist are rare chromaffin cell tumors termed paragangliomas. Within the head and neck region, they commonly arise from the carotid body, vagus nerve (glomus vagale), and jugular vein (glomus jugulare). Other vascular head and neck tumors include sinonasal malignancies, because of proximity to or involvement of the pterygoid plexus as well as the rich vascularity of the sinonasal mucosa; juvenile nasopharyngeal angiofibroma, a vascular tumor of male adolescents; unusual vascular tumors such as hemangiopericytoma; and metastatic renal cell cancer, which has a proclivity for an unusually rich blood supply...
June 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27266239/five-synchronous-paragangliomas-of-the-head-and-neck-a-case-report
#18
Davin Yavapolkul, Tatsanachat Jittreetat
This is a case report of synchronous bilateral carotid body tumor, bilateral jugulotympanic and left subclavian paraganglioma in a 38-year-old man who presented with a history of slow-growing bilateral neck masses for 4 years and a one-month history of right facial palsy, tinnitus, and hearing loss. A discussion of this case is followed by a review of the literature surrounding this rare clinical entity.
February 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27226004/symptomatic-trigeminal-neuralgia-and-nocturnal-thunderclap-headache-resulting-from-a-carotid-paraganglioma
#19
Justin M DeLange, Katherine Riordan, Srijana Zarkou
No abstract text is available yet for this article.
May 25, 2016: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/27213651/-paraganglioma-of-the-middle-ear-the-retrospective-analysis-of-the-results-of-the-surgical-treatment
#20
R M Rzaev, Rt R Rzaev
The objective of the present study was to analyze the results of and to summarize the experience with diagnostics and surgical treatment of the patients presenting with paraganglioma of the middle ear (PME). A total of 5 patients were available for the examination (all of the women) including two in whom the extension of the tumour corresponded to class A paraganglioma (according to the classification of U. Fisch) and three with class B paraganglioma (two having the tumour that occupied mezo- and hypotympanum and one with the tumour extending into the infralabyrinthine space)...
2016: Vestnik Otorinolaringologii
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