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https://www.readbyqxmd.com/read/29626183/primary-basosquamous-carcinoma-of-the-lower-eyelid-with-ocular-invasion-a-case-report
#1
Georgios Ouilson Papadopoulos, Eleni Charitonidi, Nikolaos Filippou, Domna Fanidou, Dimitrios Filippou, Panagiotis Scandalakis
INTRODUCTION: Ocular invasion is extremely rare for a primary eyelid Basosquamous Carcinoma (BSC). It can however occur in neglected cases if the clinical signs are overseen and the BSC is misdiagnosed for a less aggressive skin carcinoma. MATERIALS AND METHODS: A 58-year-old man suffering from an inferior eyelid BSC that had been neglected for 7 years was referred to our clinic. A local infiltration of the maxillary sinus and the contents of the orbit by the tumor was discovered, and he was managed with a left orbital exenteration and resection of the involved orbital bone...
March 26, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29607824/lymphoid-proliferation-in-eyelid-a-primary-follicular-lymphoma-case
#2
Deivy Cruzado-Sánchez, Walter Andree Tellez, Solon Serpa-Frias, Grisnery Maquera
Ocular adnexal lymphoma (OAL) constitutes 8% of all extranodal lymphomas, being rare in the eyelids (5-20%). The objective was to report a case of eyelid follicular lymphoma in a young adult woman. A 35-year-old female with swelling in left lower eyelid with development for 2 months. The visual acuity was 20/20 in both eyes, the tumor mass was 3 cm wide and 1.5 cm long. The contrast-enhanced computed tomography showed a soft-tissue injury in the left lower eyelid but had no signs of local spread according to description...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29563690/eyelid-sebaceous-gland-carcinoma-varied-presentations-and-reconstruction-outcome
#3
Syed Ali Raza Rizvi, Md Shahid Alam, Kafil Akhtar
PURPOSE: To analyze varying clinical presentations, histopathological features, and management outcome of sebaceous gland carcinoma (SGC) of the eyelid. MATERIALS AND METHODS: We retrospectively reviewed medical records of 30 patients with histologically proven cases of SGC of eyelid treated at tertiary care hospital. RESULTS: Patients were in the age group of 28-80 years, among which 18 (60%) were females and 12 (40%) were males. Mean follow-up period was 29...
January 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29543619/treatment-for-lentigo-maligna-of-the-head-and-neck-survey-of-practices-in-ontario-canada
#4
Annie Liu, Alexis Botkin, Christian Murray, David Goldstein, Stefan O P Hofer, Nowell Solish, Jessica Kitchen, An-Wen Chan
BACKGROUND: Lentigo maligna is an in situ form of cutaneous melanoma that commonly arises on the head and neck. Various surgical and nonsurgical treatment options are available but no randomized trials exist to guide practice. OBJECTIVE: To determine the current treatment practices for lentigo maligna of the head and neck in Ontario, Canada. MATERIALS AND METHODS: Cross-sectional survey of dermatologists, plastic surgeons, and head and neck surgeons...
March 13, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29538586/largest-case-series-of-latin-american-eyelid-tumors-over-13-years-from-a-single-center-in-sao-paulo-brazil
#5
Jéssica Carolinne Damasceno, Jordan Isenberg, Laíse Rondon Lopes, Bernardo Hime, Bruno F Fernandes, Marcia Lowen, Luis Marcelo Aranha Camargo, Rubens N Belfort
PURPOSE: Malignant lesions of the eyelid are the most common eye cancers. Although rarely lethal, late diagnosis can lead to serious visual morbidity. Definitive diagnosis of neoplastic lesions is pathological. Indications and types of eyelid lesions in a single high-volume ophthalmic reference center in Sao Paulo, Brazil, were analyzed. METHODS: The surgical pathological reports of patients who underwent eye removal procedures between January 2000 and December 2012 were retrieved from the electronic database of the Ophthalmology Department and retrospectively reviewed...
January 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29532988/h%C3%A3-bner-s-eyelid-reconstruction-using-a-free-tarsomarginal-autograft-in-eight-dogs-a-retrospective-study
#6
Anne-Sophie Poinsard, Iona Mathieson, Olivier Balland
OBJECTIVE: The aim of our work was to study the potential of tarsomarginal grafting technique, in canine. ANIMAL STUDIED: All dogs included in this study had tumors of the upper or lower eyelid. Furthermore, resection of the tumor necessitated excision of the eyelid margin comprising 1/4 and 2/3. PROCEDURE: Harvesting of the graft with the length of half the length of the tumor, including its free margins was performed via a full-thickness incision on the ipsilateral healthy eyelid...
March 13, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29521763/long-term-outcomes-of-acellular-dermal-allograft-as-a-tarsal-substitute-in-the-reconstruction-of-extensive-eyelid-defects
#7
Kaveh Vahdani, Debrelle Lou Siapno, Jung Hye Lee, Kyung In Woo, Yoon-Duck Kim
PURPOSE: To report the long-term outcomes of using acellular dermal allograft (ADA) as a tarsal substitute for reconstruction of large full-thickness eyelid defects where ipsilateral or contralateral eyelid donor tissue was either not available or tarsoconjunctival transfer was insufficient to cover the full extent of the defect. METHODS: A retrospective review of a consecutive series of 10 patients between May 2003 and April 2012. Main outcome measures were anatomical and functional outcomes and complications...
March 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29520316/blood-perfusion-in-a-full-thickness-eyelid-flap-investigated-by-laser-doppler-velocimetry-laser-speckle-contrast-imaging-and-thermography
#8
Rafi Sheikh, Khashayar Memarzadeh, Christian Torbrand, Jonas Blohmé, Sandra Lindstedt, Malin Malmsjö
Purpose: The eyelid is commonly dissected and divided in the process of, for example, blepharotomy, entropion repair, or when preparing a full-thickness eyelid flap to reconstruct a tumor defect. No study has yet been conducted to examine how perfusion in an eyelid is affected by dissection, using modern imaging techniques. Methods: The eyelid was divided with a 10-mm vertical incision, 5 mm from the medial canthus, and the incision was extended horizontally by 30 mm to provide a full-thickness eyelid. Blood perfusion was measured along the length of the free dissected eyelid using both laser Doppler velocimetry and laser speckle contrast imaging...
2018: Eplasty
https://www.readbyqxmd.com/read/29505467/biopsy-proven-metastatic-merkel-cell-carcinoma-to-the-orbit-case-report-and-review-of-literature
#9
Dean R Cugley, Samuel J Roberts-Thomson, Alan A McNab, Zelda Pick
Merkel cell carcinoma is a rare neuroendocrine tumor of subspecialized dermal mechanoreceptors, associated with immunosuppression. The usual ophthalmic presentation is an eyelid lesion. The authors present a case of biopsy-proven orbital metastatic Merkel cell carcinoma in the absence of any eyelid lesion, in an immunosuppressed patient with a history of multiple cancers. There are to the authors' knowledge only 2 other case reports of presumed metastatic Merkel cell carcinoma to the orbit, though neither were biopsied...
March 2, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29503943/androgen-receptor-positive-ductal-adenocarcinoma-of-the-nasolacrimal-duct-a-case-report
#10
In Ah Park, Ho-Seok Sa, Yoo-Sam Chung, Kyung-Ja Cho
Purpose: Primary ductal adenocarcinoma arising in the structures of the lacrimal apparatus is extremely rare, and the entity is considered a lacrimal counterpart of salivary duct carcinoma, of which the majority are known to express androgen receptor (AR). Less than 10 cases of AR-positive carcinomas of lacrimal gland or lacrimal sac have been described. Observations: We present a primary ductal adenocarcinoma with AR expression involving the nasolacrimal duct of a middle-aged patient who had suffered from right eyelid swelling, diplopia and epiphora for 4 months...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29503935/lacrimal-gland-enlargement-as-an-early-clinical-or-radiological-sign-in-thyroid-orbitopathy
#11
James Khu, Kenn A Freedman
Purpose: Characteristic ophthalmic signs of Thyroid Orbitopathy (TO) include exophthalmos, eyelid retraction, eyelid edema, restrictive extraocular myopathy, and optic neuropathy. In addition lacrimal gland (LG) enlargement can be observed in these patients. However TO has not usually been considered in the differential diagnosis of cases of isolated LG enlargement. Observations: A female patient at our institution (Texas Tech) was seen over a period from 2006 to 2012...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29496505/hypoxia-modulates-the-development-of-a-corneal-stromal-matrix-model
#12
Albert Lee, Dimitrios Karamichos, Obianamma E Onochie, Audrey E K Hutcheon, Celeste B Rich, James D Zieske, Vickery Trinkaus-Randall
Deposition of matrix proteins during development and repair is critical to the transparency of the cornea. While many cells respond to a hypoxic state that can occur in a tumor, the cornea is exposed to hypoxia during development prior to eyelid opening and during the diurnal sleep cycle where oxygen levels can drop from 21% to 8%. In this study, we used 2 three-dimensional (3-D) models to examine how stromal cells respond to periods of acute hypoxic states. The first model, a stromal construct model, is a 3-D stroma-like construct that consists of human corneal fibroblasts (HCFs) stimulated by a stable form of ascorbate for 1, 2, and 4 weeks to self-assemble their own extracellular matrix...
February 26, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29480265/isolated-neurofibroma-of-the-eyelid-mimicking-recurrent-chalazion
#13
H Vijaya Pai, Surabhi Abbagani, Padma Priya Jaishankar
Neurofibroma is a peripheral nerve sheath tumor which is seen in neurofibromatosis type 1 and is characterized by various ophthalmic manifestations. Solitary neurofibroma of the eyelid is rare. We report a case of a 53-year-old female patient who presented with a painless swelling in the left upper lid of 4 years' duration. She had undergone surgery for the same lesion twice. The lesion was excised and histopathological examination revealed a solitary neurofibroma. She did not have any other features of generalized neurofibromatosis...
March 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29468227/solitary-mastocytoma-in-the-eyelid-of-an-adult
#14
Elizabeth L McKinnon, Andrew J Rand, Alan D Proia
Purpose: To describe the ophthalmic symptoms and histopathological findings in a rare case of an eyelid mastocytoma in an adult. Observations: A man in his early 60s developed a painless, non-tender, non-pruritic, mobile nodule on the right lower eyelid beneath the inferior orbital rim. The lesion grew to 15 × 9 mm over eleven months. Biopsy revealed a diffuse infiltrate of histiocytoid and spindle-shaped mast cells forming cords and small nests between collagen fibers in the superficial and deep dermis...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29462449/endoscopic-transorbital-superior-eyelid-approach-for-the-management-of-selected-spheno-orbital-meningiomas-preliminary-experience
#15
Iacopo Dallan, Stefano Sellari-Franceschini, Mario Turri-Zanoni, Matteo de Notaris, Giacomo Fiacchini, Francesca Romana Fiorini, Paolo Battaglia, Davide Locatelli, Paolo Castelnuovo
BACKGROUND: Feasibility and safety of spheno-orbital meningioma resection by means of endoscopic-assisted transorbital route. OBJECTIVE: To evaluate the feasibility and outcomes of the transorbital endoscopic management of selected spheno-orbital meningiomas. As secondary aims, symptom improvement and tumor volume removed were evaluated. METHODS: Retrospective chart evaluation of patients with spheno-orbital meningiomas treated by means of endoscopic transorbital superior eyelid approach in 3 referral centers over the last 4 yr...
March 1, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29423837/analysis-of-hedgehog-signaling-in-periocular-sebaceous-carcinoma
#16
John C Bladen, Mariya Moosajee, Dhani Tracey-White, Michèle Beaconsfield, Edel A O'Toole, Michael P Philpott
PURPOSE: Sebaceous carcinoma (SC) is a clinical masquerader of benign conditions resulting in significant eye morbidity, sometimes leading to extensive surgical treatment including exenteration, and even mortality. Little is known about the genetic or molecular basis of SC. This study identifies the involvement of Hedgehog (Hh) signaling in periocular SC. METHODS: Fifteen patients with periocular SC patients were compared to 15 patients with eyelid nodular basal cell carcinoma (nBCC; a known Hh tumor), alongside four normal individuals as a control for physiological Hh expression...
February 8, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29381940/topical-steroids-eye-drops-in-conjunctival-reactive-lymphoid-hyperplasia-case-report
#17
Bernardo Rodrigues Mendes Moraes, Micael Valtoni Dantas do Nascimento, Epitácio Dias da Silva Neto, Ruth Miyuki Santo
RATIONALE: Conjunctival lymphoproliferative lesions constitute a significant diagnostic challenge and it is essential to exclude neoplastic lesions. Histopathological and immunohistochemical tests are very useful in establishing the correct diagnosis. Reactive lymphoid hyperplasia (RLH) is part of a spectrum of lymphocytic infiltrative disorders. Evidence is scarce regarding appropriate treatment of conjunctival RLH. We report a case treated with topical corticosteroid. PATIENT CONCERNS: A 40 year-old female presented with a 7-month history of a slow growth tumor in the superior conjunctiva of the right eye...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29380786/melanorrhea-noncontiguous-spread-of-palpebral-conjunctival-melanoma-to-the-nasolacrimal-duct
#18
Raksha Rao, Santosh G Honavar, Michelle De Padua, Kaustubh Mulay, Vijayanand P Reddy
A 42-year-old Asian Indian male with a history of conjunctival melanoma in the left eye presented with a recurrent tumor in the upper tarsal conjunctiva. The tumor was completely excised under margin control, followed by two-staged eyelid reconstruction. During the second stage of the eyelid reconstruction, a brown-colored discharge was noted at the punctum, which on cytology was confirmatory of melanoma. Left dacryocystectomy with en bloc nasolacrimal duct (NLD) excision was performed. Histopathology demonstrated infiltration of the NLD by the tumor with no presence of melanoma in the lacrimal sac...
February 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29366363/orbital-granulomatosis-with-polyangiitis-mimicking-igg4-related-disease-in-a-12-year-old-male
#19
Anastasia Drobysheva, Julie Fuller, Cory M Pfeifer, Dinesh Rakheja
Granulomatosis with polyangiitis is rare in children. We report a case of a 12-year-old male who presented with new symptoms of left eyelid swelling and ptosis. Magnetic resonance imaging showed an enhancing orbital mass suspicious for a neoplasm. Excisional biopsy was performed. Microscopic examination revealed fibrovascular tissue with dense collagenous fibrosis and mixed inflammatory infiltrate that included many plasma cells. Many small and medium-sized blood vessels showed granulomatous and necrotizing vasculitis with disruption of the vessel walls and fibrinoid necrosis...
January 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29366305/primary-cutaneous-mucinous-carcinoma-with-extramammary-paget-s-disease-eccrine-or-apocrine
#20
Sun-Ju Oh, Young-Ok Kim
Primary cutaneous mucinous carcinoma (PCMC) is an uncommon tumor of the sweat gland origin. The occurrence of PCMC is mostly in middle-aged and older patients, with a slight male predominance. Most cases of PCMC arise on the head, with a preference for eyelids. The histogenesis of PCMC, whether eccrine or apocrine, remains controversial. We report a rare case of PCMC with secondary extramammary Paget's disease in the groin of a 75-year-old man, which favored an apocrine origin. Furthermore, based on a review of the literature, we provide several histologic clues that can be used to differentiate PCMC from metastatic mucinous carcinoma...
January 25, 2018: Journal of Pathology and Translational Medicine
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