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Brain surface mri

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https://www.readbyqxmd.com/read/29914037/mapping-the-proxies-of-memory-and-learning-function-in-senior-adults-with-high-performing-normal-aging-and-neurocognitive-disorders
#1
Hanna Lu, Ni Xi, Ada W T Fung, Linda C W Lam
BACKGROUND: Memory and learning, as the core brain function, shows controversial results across studies focusing on aging and dementia. One of the reasons is because of the multi-faceted nature of memory and learning. However, there is still a dearth of comparable proxies with psychometric and morphometric portrait in clinical and non-clinical populations. OBJECTIVE: We aim to investigate the proxies of memory and learning function with direct and derived measures and examine their associations with morphometric features in senior adults with different cognitive status...
June 9, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29911279/early-adolescent-brain-markers-of-late-adolescent-academic-functioning
#2
Alejandro Daniel Meruelo, Joanna Jacobus, Erick Idy, Tam Nguyen-Louie, Gregory Brown, Susan Frances Tapert
Academic performance in adolescence strongly influences adult prospects. Intelligence quotient (IQ) has historically been considered a strong predictor of academic performance. Less objectively explored have been morphometric features. We analyzed brain MRI morphometry metrics in early adolescence (age 12-14 years) as quantitative predictors of academic performance over high school using a naïve Bayesian classifier approach with n = 170 subjects. Based on the mean GPA, subjects were divided into high (GPA ≥3...
June 18, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29910528/improved-stability-of-whole-brain-surface-parcellation-with-multi-atlas-segmentation
#3
Yuankai Huo, Shunxing Bao, Prasanna Parvathaneni, Bennett A Landman
Whole brain segmentation and cortical surface parcellation are essential in understanding the brain anatomical-functional relationship. Multi-atlas segmentation has been regarded as one of the leading segmentation methods for the whole brain segmentation. In our recent work, the multi-atlas technique has been adapted to surface reconstruction using a method called Multi-atlas CRUISE (MaCRUISE). The MaCRUISE method not only performed the consistent volume-surface analyses but also shown advantages on robustness compared with FreeSurfer method...
March 2018: Proceedings of SPIE
https://www.readbyqxmd.com/read/29905844/robotic-assisted-mri-guided-interventional-interstitial-mr-guided-focused-ultrasound-ablation-in-a-swine-model
#4
Jacquelyn MacDonell, Niravkumar Patel, Gregory Fischer, E Clif Burdette, Jiang Qian, Vaibhav Chumbalkar, Goutam Ghoshal, Tamas Heffter, Emery Williams, Matthew Gounis, Robert King, Juliette Thibodeau, Gene Bogdanov, Olivia W Brooks, Erin Langan, Roy Hwang, Julie G Pilitsis
BACKGROUND: Ablative lesions are current treatments for epilepsy and brain tumors. Interstitial magnetic resonance (MR) guided focused ultrasound (iMRgFUS) may be an alternate ablation technique which limits thermal tissue charring as compared to laser therapy (LITT) and can produce larger ablation patterns nearer the surface than transcranial MR guided focused ultrasound (tcMRgFUS). OBJECTIVE: To describe our experience with interstitial focused ultrasound (iFUS) ablations in swine, using MR-guided robotically assisted (MRgRA) delivery...
June 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29904338/spanol-spectral-analysis-of-lobes-a-spectral-clustering-framework-for-individual-and-group-parcellation-of-cortical-surfaces-in-lobes
#5
Julien Lefèvre, Antonietta Pepe, Jennifer Muscato, Francois De Guio, Nadine Girard, Guillaume Auzias, David Germanaud
Understanding the link between structure, function and development in the brain is a key topic in neuroimaging that benefits from the tremendous progress of multi-modal MRI and its computational analysis. It implies, inter alia , to be able to parcellate the brain volume or cortical surface into biologically relevant regions. These parcellations may be inferred from existing atlases (e.g., Desikan) or sets of rules, as would do a neuroanatomist for lobes, but also directly driven from the data (e.g., functional or structural connectivity) with minimum a priori...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29899686/cortical-statistical-correlation-tomography-of-eeg-resting-state-networks
#6
Chuang Li, Han Yuan, Guofa Shou, Yoon-Hee Cha, Sridhar Sunderam, Walter Besio, Lei Ding
Resting state networks (RSNs) have been found in human brains during awake resting states. RSNs are composed of spatially distributed regions in which spontaneous activity fluctuations are temporally and dynamically correlated. A new computational framework for reconstructing RSNs with human EEG data has been developed in the present study. The proposed framework utilizes independent component analysis (ICA) on short-time Fourier transformed inverse source maps imaged from EEG data and statistical correlation analysis to generate cortical tomography of electrophysiological RSNs...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29896087/changes-of-visual-pathway-and-brain-connectivity-in-glaucoma-a-systematic-review
#7
Raffaele Nuzzi, Laura Dallorto, Teresa Rolle
Background: Glaucoma is a leading cause of irreversible blindness worldwide. The increasing interest in the involvement of the cortical visual pathway in glaucomatous patients is due to the implications in recent therapies, such as neuroprotection and neuroregeneration. Objective: In this review, we outline the current understanding of brain structural, functional, and metabolic changes detected with the modern techniques of neuroimaging in glaucomatous subjects. Methods: We screened MEDLINE, EMBASE, CINAHL, CENTRAL, LILACS, Trip Database, and NICE for original contributions published until 31 October 2017...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29893758/early-and-rapid-detection-of-uchl1-in-the-serum-of-brain-trauma-patients-a-novel-gold-nanoparticle-based-method-for-diagnosing-the-severity-of-brain-injury
#8
Gyaninder Pal Singh, Richa Nigam, Gaurav Singh Tomar, Mohan Monisha, Sanjeev Kumar Bhoi, Arulselvi S, Kangana Sengar, Deepa Akula, Prashanth Panta, Roy Anindya
The clinical diagnosis of traumatic brain injury (TBI) is based on neurological examination and neuro-imaging tools such as CT scanning and MRI. However, neurological examination at times may be confounded by consumption of alcohol or drugs and neuroimaging facilities may not be available at all centers. Human ubiquitin C-terminal hydrolase (UCHL1) is a well-accepted serum biomarker for severe TBI and can be used to detect the severity of a head injury. A reliable, rapid, cost effective, bedside and easy to perform method for the detection of UCHL1 is a pre-requisite for wide clinical applications of UCHL1 as a TBI biomarker...
June 12, 2018: Analyst
https://www.readbyqxmd.com/read/29890276/both-dbs-and-thalamotomy-in-a-13-year-old-patient-with-primary-dystonia-a-case-report
#9
Hai Lin, Xiao-Dong Cai, Dou-Dou Zhang, Jia-Li Liu, Wei-Ping Li
BACKGROUND: Primary dystonia is a neurological disease with the characteristics of abnormal, involuntary twisting and turning movements, which greatly affects life quality of patients. Treatments for dystonia consist of oral medications, botulinum neurotoxin injections, physical therapy and surgeries. For medication-refractory dystonia, surgeries, especially deep brain stimulation (DBS), are the optimal option. CASE DESCRIPTION: the patient was a 13-year-old boy suffering from extremely severe primary dystonia, with a BFMDRS-M score of 118 and a TWSTRS-S score of 29...
June 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29882044/post-gadolinium-3-dimensional-spatial-surface-and-structural-characteristics-of-glioblastomas-differentiate-pseudoprogression-from-true-tumor-progression
#10
Madison R Hansen, Edward Pan, Andrew Wilson, Morgan McCreary, Yeqi Wang, Thomas Stanley, Marco C Pinho, Xiaohu Guo, Darin T Okuda
PURPOSE: Pseudoprogression is often indistinguishable from true tumor progression on conventional 2-dimensional (2D) MRI in glioblastoma multiforme (GBM) patients. The aim of this study was to determine the association between post-gadolinium 3-dimensional (3D) characteristics and clinical state in GBM patients. METHODS: Standardized 3D brain MRI studies were performed, and contrast enhancing portions of each tumor were segmented and analyzed, blinded to clinical state, using principal component analysis (PCA), medial axis transformation (MAT), and coverage analysis...
June 7, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29876759/inter-observer-variation-of-hippocampus-delineation-in-hippocampal-avoidance-prophylactic-cranial-irradiation
#11
F Bartel, M van Herk, H Vrenken, F Vandaele, S Sunaert, K de Jaeger, N J Dollekamp, C Carbaat, E Lamers, E M T Dieleman, Y Lievens, D de Ruysscher, S B Schagen, M B de Ruiter, J C de Munck, J Belderbos
BACKGROUND: Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) techniques have been developed to reduce radiation damage to the hippocampus. An inter-observer hippocampus delineation analysis was performed and the influence of the delineation variability on dose to the hippocampus was studied. MATERIALS AND METHODS: For five patients, seven observers delineated both hippocampi on brain MRI. The intra-class correlation (ICC) with absolute agreement and the generalized conformity index (CIgen ) were computed...
June 6, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29874295/a-scalable-method-to-improve-gray-matter-segmentation-at-ultra-high-field-mri
#12
Omer Faruk Gulban, Marian Schneider, Ingo Marquardt, Roy A M Haast, Federico De Martino
High-resolution (functional) magnetic resonance imaging (MRI) at ultra high magnetic fields (7 Tesla and above) enables researchers to study how anatomical and functional properties change within the cortical ribbon, along surfaces and across cortical depths. These studies require an accurate delineation of the gray matter ribbon, which often suffers from inclusion of blood vessels, dura mater and other non-brain tissue. Residual segmentation errors are commonly corrected by browsing the data slice-by-slice and manually changing labels...
2018: PloS One
https://www.readbyqxmd.com/read/29869489/investigational-pet-tracers-for-high-grade-gliomas
#13
Gagandeep Choudhary, Karl-Josef Langen, Norbert Galldiks, Jonathan Mcconathy
High-grade gliomas (HGGs) are the most common primary malignant tumors of the brain, with glioblastoma (GBM) constituting over 50% of all the gliomas in adults. The disease carries very high mortality, and even with optimal treatment, the median survival is 2-5 years for anaplastic tumors and 1-2 years for GBMs. Neuroimaging is critical to managing patients with HGG for diagnosis, treatment planning, response assessment, and detecting recurrent disease. Magnetic resonance imaging (MRI) is the cornerstone of imaging in neuro-oncology, but molecular imaging with positron emission tomography (PET) can overcome some of the inherent limitations of MRI...
June 4, 2018: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29868447/anatomic-metabolic-brain-markers-of-the-m-3243a-g-mutation-a-multi-parametric-7t-mri-study
#14
Roy A M Haast, Dimo Ivanov, Rutger J T IJsselstein, Suzanne C E H Sallevelt, Jacobus F A Jansen, Hubert J M Smeets, Irenaeus F M de Coo, Elia Formisano, Kâmil Uludağ
One of the most common mitochondrial DNA (mtDNA) mutations, the A to G transition at base pair 3243, has been linked to changes in the brain, in addition to commonly observed hearing problems, diabetes and myopathy. However, a detailed quantitative description of m.3243A>G patients' brains has not been provided so far. In this study, ultra-high field MRI at 7T and volume- and surface-based data analyses approaches were used to highlight morphology (i.e. atrophy)-, microstructure (i.e. myelin and iron concentration)- and metabolism (i...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29867737/gold-nanoparticles-for-brain-tumor-imaging-a-systematic-review
#15
Antonio Meola, Jianghong Rao, Navjot Chaudhary, Mayur Sharma, Steven D Chang
Background: Demarcation of malignant brain tumor boundaries is critical to achieve complete resection and to improve patient survival. Contrast-enhanced brain magnetic resonance imaging (MRI) is the gold standard for diagnosis and pre-surgical planning, despite limitations of gadolinium (Gd)-based contrast agents to depict tumor margins. Recently, solid metal-based nanoparticles (NPs) have shown potential as diagnostic probes for brain tumors. Gold nanoparticles (GNPs) emerged among those, because of their unique physical and chemical properties and biocompatibility...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29867332/a-fully-automated-subcortical-and-ventricular-shape-generation-pipeline-preserving-smoothness-and-anatomical-topology
#16
Xiaoying Tang, Yuan Luo, Zhibin Chen, Nianwei Huang, Hans J Johnson, Jane S Paulsen, Michael I Miller
In this paper, we present a fully-automated subcortical and ventricular shape generation pipeline that acts on structural magnetic resonance images (MRIs) of the human brain. Principally, the proposed pipeline consists of three steps: (1) automated structure segmentation using the diffeomorphic multi-atlas likelihood-fusion algorithm; (2) study-specific shape template creation based on the Delaunay triangulation; (3) deformation-based shape filtering using the large deformation diffeomorphic metric mapping for surfaces...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29863569/autologous-fat-used-for-facial-filling-can-lead-to-massive-cerebral-infarction-through-middle-cerebral-artery-or-facial-intracranial-branches
#17
Xian Wang, Min Wu, Xing Zhou, Hengdeng Liu, Yongchao Zhang, Haiping Wang
BACKGROUND: Autologous fat injection is a procedure aimed at eliminating grave defects in the skin surface by subcutaneous injection of the patient's fatty tissue. Fat embolism is a rare but severe complication of this procedure, especially cerebral infarction. It is first reported by Thaunat in 2004. METHODS: were presented to the hospital with sudden unconsciousness and left limb weakness in 24 hours after facial fat injection. Brain computed tomography and magnetic resonance imaging were performed immediately after admission...
May 31, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29862735/-hippocampus-mri-parallel-segmentation-using-three-dimensions-lattice-boltzmann-model-with-prior-information
#18
Jizhe Wang, Zhuangzhi Yan, Junling Wen
Getting volume change of hippocampus by segmenting on brain MRI is an important step in the diagnose of Alzheimer's disease and other brain disease. Three dimensional segmentation can make use of the correlation of image in gray and spatial position, so it has high accuracy. This paper proposes a novel three-dimensional lattice Boltzmann model combined with the surface evolution of deformable model and taking the prior information as an external force term to constrain the evolution of three dimensional surfaces...
January 30, 2018: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
https://www.readbyqxmd.com/read/29852280/concentric-radiofrequency-arrays-to-increase-the-statistical-power-of-resting-state-maps-in-monkeys
#19
Kyle M Gilbert, David J Schaeffer, Peter Zeman, Jörn Diedrichsen, Stefan Everling, Julio C Martinez-Trujillo, J Andrew Pruszynski, Ravi S Menon
The close homology of monkeys and humans has increased the prevalence of non-human-primate models in functional MRI studies of brain connectivity. To improve upon the attainable resolution in functional MRI studies, a commensurate increase in the sensitivity of the radiofrequency receiver coil is required to avoid a reduction in the statistical power of the analysis. Most receive coils are comprised of multiple loops distributed equidistantly over a surface to produce spatially independent sensitivity profiles...
May 28, 2018: NeuroImage
https://www.readbyqxmd.com/read/29851460/nanosensors-for-the-chemical-imaging-of-acetylcholine-using-magnetic-resonance-imaging
#20
Yi Luo, Eric H Kim, Chris A Flask, Heather A Clark
A suite of imaging tools for detecting specific chemicals in the central nervous system could accelerate the understanding of neural signaling events critical to brain function and disease. Here, we introduce a class of nanoparticle sensors for the highly-specific detection of acetylcholine in the living brain using magnetic resonance imaging (MRI). The nanosensor is composed of acetylcholine-catalyzing enzymes and pH-sensitive gadolinium contrast agents co-localized onto the surface of polymer nanoparticles which leads to changes in T1 relaxation rate (1/T1)...
May 31, 2018: ACS Nano
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