Lin Chang, William D Chey, Aamer Imdad, Christopher V Almario, Adil E Bharucha, Susan Diem, Katarina B Greer, Brian Hanson, Lucinda A Harris, Cynthia Ko, M Hassan Murad, Amit Patel, Eric D Shah, Anthony J Lembo, Shahnaz Sultan
INTRODUCTION: Chronic idiopathic constipation (CIC) is a common disorder associated with significant impairment in quality of life. This clinical practice guideline, jointly developed by the American Gastroenterological Association and the American College of Gastroenterology, aims to inform clinicians and patients by providing evidence-based practice recommendations for the pharmacological treatment of CIC in adults. METHODS: The American Gastroenterological Association and the American College of Gastroenterology formed a multidisciplinary guideline panel that conducted systematic reviews of the following agents: fiber, osmotic laxatives (polyethylene glycol, magnesium oxide, lactulose), stimulant laxatives (bisacodyl, sodium picosulfate, senna), secretagogues (lubiprostone, linaclotide, plecanatide), and serotonin type 4 agonist (prucalopride)...
June 1, 2023: American Journal of Gastroenterology