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https://www.readbyqxmd.com/read/29351243/awake-versus-asleep-deep-brain-stimulation-surgery-technical-considerations-and-critical-review-of-the-literature
#1
REVIEW
Ryan B Kochanski, Sepehr Sani
Advancements in neuroimaging have led to a trend toward direct, image-based targeting under general anesthesia without the use of microelectrode recording (MER) or intraoperative test stimulation, also referred to as "asleep" deep brain stimulation (DBS) surgery. Asleep DBS, utilizing imaging in the form of intraoperative computed tomography (iCT) or magnetic resonance imaging (iMRI), has demonstrated reliable targeting accuracy of DBS leads implanted within the globus pallidus and subthalamic nucleus while also improving clinical outcomes in patients with Parkinson's disease...
January 19, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29349735/ict-openness-and-co2-emissions-in-africa
#2
Simplice A Asongu
This study investigates how information and communication technology (ICT) complements globalisation in order to influence CO2 emissions in 44 Sub-Saharan African countries over the period 2000-2012. ICT is measured with internet penetration and mobile phone penetration whereas globalisation is designated in terms of trade and financial openness. The empirical evidence is based on the generalised method of moments. The findings broadly show that ICT can be employed to dampen the potentially negative effect of globalisation on environmental degradation like CO2 emissions...
January 18, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29348088/prevalence-of-hepatitis-c-virus-and-its-risk-factors-in-blood-donors-in-district-peshawar
#3
Noor Rehman, M Bilal Orakzai, Azam Hayat, Sadiq Azam, Bashir Ahmad, Ibrar Khan, Zermina Zeb
The current study was designed in order to elucidate the most sensitive method for daily practice as well as to evaluate the risk factors for HCV infection associated with blood transfusion in District Peshawar. A total of 1400 healthy volunteer blood donors were tested for Anti-HCV. A questionnaire was used to evaluate the risk factors. Initial testing of all blood samples was done by Immuno Chromatographic Technique (ICT) and confirmed by micro particle enzyme immunoassay (MEIA) and Enzyme Linked Immunosorbent Assay (ELISA)...
January 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29345699/theoretical-investigations-on-the-unsymmetrical-effect-of-%C3%AE-link-zn-porphyrin-sensitizers-on-the-performance-for-dye-sensitized-solar-cells
#4
Miao Xie, Fu-Quan Bai, Jinjian Wang, Yue-Qing Zheng, Zhenyang Lin
Dye sensitizers play an important role in dye-sensitized solar cells (DSSCs). As a promising strategy for the design of novel porphyrin sensitizers, the asymmetric modification of the porphyrin ring to meso-link porphyrin sensitizer has emerged in recent years, which can improve the light-harvesting properties and enhance the electron distribution. In this work, in order to reveal the essence of the effect of unsymmetrical substitution on the performance of β-link porphyrin dyes in DSSCs, four kinds of common β-link porphyrin dyes with different structures are calculated by using density functional theory (DFT) and time-dependent density functional theory (TD-DFT)...
January 18, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29336722/perceptions-on-technology-for-volunteer-respite-care-for-bedridden-elders-in-chile
#5
Esmeralda Abarca, Solange Campos, Valeria Herskovic, Carolina Fuentes
PURPOSE:  Informal caregivers of bedridden elders need a respite. One form of obtaining a respite is through volunteers who are contacted by means of information and communication technology (ICT). METHOD:  A qualitative study was carried out in a low-income district in Santiago, Chile, to learn about how caregivers of bedridden elders perceive the possibility of using ICT to access this respite. In-depth interviews were carried out and transcribed verbatim, then analysed using open coding...
December 2018: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/29330674/advances-in-serological-imaging-techniques-and-molecular-diagnosis-of-toxoplasma-gondii-infection
#6
REVIEW
Ali Rostami, Panagiotis Karanis, Shirzad Fallahi
BACKGROUND: Toxoplasmosis is worldwide distributed zoonotic infection disease with medical importance in immunocompromised patients, pregnant women and congenitally infected newborns. Having basic information on the traditional and new developed methods is essential for general physicians and infectious disease specialists for choosing a suitable diagnostic approach for rapid and accurate diagnosis of the disease and, consequently, timely and effective treatment. METHODS: We conducted English literature searches in PubMed from 1989 to 2016 using relevant keywords and summarized the recent advances in diagnosis of toxoplasmosis...
January 12, 2018: Infection
https://www.readbyqxmd.com/read/29327004/photoinduced-ict-vs-excited-rotamer-intercoversion-in-two-quadrupolar-polyaromatic-n-methylpyridinium-cations
#7
A Cesaretti, B Carlotti, F Elisei, C G Fortuna, A Spalletti
The excited state dynamics of two quadrupolar polyaromatic N-methylpyridinium cations have been fully investigated in order to acquire detailed information on their photo-induced behavior. The two molecules are symmetric push-pull compounds having a D-π-A+-π-D motif, with the same electron-acceptor central unit (A = N-methylpyridinium) and two distinctive electron-donor polyaromatic side groups (D), namely naphthyl and pyrenyl substituents. Both molecules undergo charge transfer during the absorption, as revealed by a significant solvatochromism exhibited with solvent polarity, but the fate of their excited state was found to be markedly different...
January 12, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29319148/bridging-gaps-in-health-information-systems-a-case-study-from-somaliland-somalia
#8
Ahmed Askar, Malekafzali Ardakani, Reza Majdzade
Reliable and timely health information is fundamental for health information systems (HIS) to work effectively. This case study aims to assess Somaliland HIS in terms of its contextual situation, major weaknesses and proposes key evidence-based recommendations. Data were collected through national level key informants' interviews, observations, group discussion and scoring using the HIS framework and assessment tool developed by World Health Organization Health Metrics Network (WHO/HMN). The study found major weaknesses including: no policy, strategic plan and legal framework in place; fragmented sub-information systems; Poor information and communications technology (ICT) infrastructure; poorly motivated and under-skilled personnel; dependence on unsustainable external funds; no census or civil registration in place; data from private health sector not captured; insufficient technical capacity to analyse data collected by HIS; and information is not widely shared, disseminated or utilized for decision-making...
January 2, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29317384/identifying-opinion-leaders-to-promote-organ-donation-on-social-media-network-study
#9
Jingyuan Shi, Charles T Salmon
BACKGROUND: In the recent years, social networking sites (SNSs, also called social media) have been adopted in organ donation campaigns, and recruiting opinion leaders for such campaigns has been found effective in promoting behavioral changes. OBJECTIVE: The aim of this paper was to focus on the dissemination of organ donation tweets on Weibo, the Chinese equivalent of Twitter, and to examine the opinion leadership in the retweet network of popular organ donation messages using social network analysis...
January 9, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29313675/aggregation-induced-emission-enhancement-from-disilane-bridged-donor-acceptor-donor-luminogens-based-on-the-triarylamine-functionality
#10
Tsukasa Usuki, Masaki Shimada, Yoshinori Yamanoi, Tatsuhiko Ohto, Hirokazu Tada, Hidetaka Kasai, Eiji Nishibori, Hiroshi Nishihara
Six novel donor-acceptor-donor organic dyes containing a Si-Si moiety based on triarylamine functionalities as donor units were prepared by Pd-catalyzed arylation of hydrosilanes. Their photophysical, electrochemical, and structural properties were studied in detail. Most of the compounds showed attractive photoluminescence (PL) and electrochemical properties both in solution and in the solid state because of intramolecular charge transfer (ICT), suggesting these compounds could be useful for electroluminescence (EL) applications...
January 9, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29313245/effect-of-post-traumatic-stress-disorder-on-cognitive-function-and-covert-hepatic-encephalopathy-diagnosis-in-cirrhotic-veterans
#11
Thomas K Burroughs, James B Wade, Michael S Ellwood, Andrew Fagan, Douglas M Heuman, Michael Fuchs, Jasmohan S Bajaj
BACKGROUND: In veterans, post-traumatic stress disorder (PTSD) is often associated with substance abuse, which in turn can lead to cirrhosis. Cirrhotic patients are prone to cognitive impairment, which is typically due to covert hepatic encephalopathy (CHE), but can also be affected by PTSD. The aim was to define the impact of PTSD on cognitive performance and the diagnosis of CHE in cirrhotic patients. METHODS: Outpatient veterans with cirrhosis underwent two separate modalities for CHE cognitive testing [Psychometric Hepatic Encephalopathy Scale (PHES) and Inhibitory Control Test (ICT)]...
January 8, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29310700/a-cross-sectional-study-of-the-filarial-and-leishmania-co-endemicity-in-two-ecologically-distinct-settings-in-mali
#12
Moussa Brema Sangare, Yaya Ibrahim Coulibaly, Siaka Yamoussa Coulibaly, Michel Emmanuel Coulibaly, Bourama Traore, Ilo Dicko, Ibrahim Moussa Sissoko, Sibiry Samake, Sekou Fantamady Traore, Thomas Bruce Nutman, Jesus Gilberto Valenzuela, Ousmane Faye, Shaden Kamhawi, Fabiano Oliveira, Roshanak Tolouei Semnani, Seydou Doumbia
BACKGROUND: Filariasis and leishmaniasis are two neglected tropical diseases in Mali. Due to distribution and associated clinical features, both diseases are of concern to public health. The goal of this study was to determine the prevalence of co-infection with filarial (Wuchereria bancrofti and Mansonella perstans) and Leishmania major parasites in two ecologically distinct areas of Mali, the Kolokani district (villages of Tieneguebougou and Bougoudiana) in North Sudan Savanna area, and the district of Kolondieba (village of Boundioba) in the South Sudan Savanna area...
January 8, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29306031/simultaneous-detection-of-dual-biomarkers-from-humans-exposed-to-organophosphorus-pesticides-by-combination-of-immunochromatographic-test-strip-and-ellman-assay
#13
Mingming Yang, Yuting Zhao, Limin Wang, Michael Paulsen, Christopher D Simpson, Fengquan Liu, Dan Du, Yuehe Lin
A novel sandwich immunoassay based immunochromatographic test strip (ICTS) has been developed for simultaneously measuring both butyrylcholinesterase (BChE) activity and the total amount of BChE (including inhibited and active enzyme) from 70 μLpost-exposure human plasma sample. The principle of this method is based on the BChE monoclonal antibody (MAb) capable of acting as both capture antibody and detection antibody. The BChE MAb which was immobilized on the test line was able to recognize both organophosphorus BChE adducts (OP-BChE) and BChE and provided equal binding affinity, permitting detection of the total enzyme amount in post-exposure human plasma samples...
December 21, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29303266/excited-state-dynamics-of-thioflavin-t-planar-stable-intermediate-revealed-by-nuclear-wave-packet-spectroscopies
#14
JunWoo Kim, Dong Eon Kim, Taiha Joo
Time-domain spectroscopies with time resolution shorter than the vibrational periods of interest were employed to reveal the reaction kinetics and molecular dynamics of the intramolecular charge transfer (ICT) reaction of thioflavin T in liquids. Time-resolved fluorescence spectra provided detailed reaction kinetics, and vibrational wave packets observed in the time-resolved fluorescence and transient absorption provided structural information of the reaction intermediate. Upon photoexcitation, the Franck-Condon state undergoes vibrational relaxation and minor conformational change to form a stable planar intermediate followed by the twisting of the central C-C single bond to form the twisted ICT state...
January 5, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29298495/-i-m-almost-never-sick-everyday-life-experiences-of-children-and-young-people-with-home-mechanical-ventilation
#15
Åsa Israelsson-Skogsberg, Lena Hedén, Berit Lindahl, Katja Laakso
Developments in medical technology and treatment have increased the survival rates of children with serious illnesses or injuries, including those receiving home mechanical ventilation, which is a small but growing group. The aim of this study was to explore everyday life experiences of children and young people living with home mechanical ventilation (HMV). Data were obtained through interviews with nine participants. The interviews were supported by photovoice methodology: photographs taken by the participants before or during the interviews were used to facilitate conversation...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29286241/multiplexed-detection-of-tumor-markers-with-multicolor-polymer-dot-based-immunochromatography-test-strip
#16
Chia-Chia Fang, Chia-Cheng Chou, Yong-Quan Yang, Wei-Kai Tsai, Yeng-Tseng Wang, Yang-Hsiang Chan
There have been ongoing efforts to develop more sensitive and fast quantitative screening of cancer markers by use of fluorometric immunochromatographic test strip (ICTS) since the remarkable advances in fluorescent nanomaterials. Semiconducting polymer dots (Pdots) have recently emerged as a new type of biocompatible fluorescent probes with extraordinary brightness which is suitable for biological and clinical use. Here we developed Pdot-based ICTS for quantitative rapid screening of prostate-specific antigen (PSA), alpha-fetoprotein (AFP), and carcinoembryonic antigen (CEA) in 10 min...
December 29, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29284911/the-most-common-smartphone-applications-used-by-medical-students-and-barriers-of-using-them
#17
Mohamad Jebraeily, Zahra Zare Fazlollahi, Bahlol Rahimi
Introduction: Medical knowledge is rapidly expanding and updating. It is very important that students can timely access to information and the latest scientific evidence without any time and place limitation. The smartphone is one of ICT tools that adopted greatly by healthcare professionals. Today, the most medical sciences universities have provided smartphone as an educational aid tool and acquisition licenses for medical apps resources in training of their students. Aim: This research was conducted to determine common smartphone applications among medical students of Urmia University of medical sciences and to identify barriers in using them...
December 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29283154/idiopathic-intracranial-hypertension-associated-with-anaemia-secondary-to-antiretroviral-drug-in-a-human-immunodeficiency-virus-positive-patient
#18
J Vijay Ananth, S Sudharshan, Ambika Selvakumar, Bella J Devaleenal, Kavitha Kalaivani, Jyotirmay Biswas
Papilledema in a patient with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome is an alarming finding. Any condition giving rise to raised intracranial tension (ICT) can cause papilledema, and in these patients, it could be secondary to opportunistic infections like meningitis to neoplasm. We report a case of a 28-year old female with HIV on antiretroviral therapy, who presented to us, with papilledema. Her fundus examination revealed superficial hemorrhages and Roth's spots along with papilledema...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29282351/marked-18-fuorine-fluorodeoxyglucose-fdg-avidity-of-an-intrapulmonary-typical-carcinoid-tumor-manifesting-as-a-bronchocele-in-an-asymptomatic-middle-aged-woman
#19
Camila Saadé-Yordán, Edward McBurney-Henriquez, Ricardo González-Santoni, Carmen Gurrea-Rosas, José Montalvo-Fitzpatrick, José A Maldonado-Vargas
BACKGROUND Intrapulmonary carcinoid tumors (ICTs) are malignant, slow-growing tumors classified as either: i) typical, less aggressive, well-differentiated tumors or ii) atypical, more aggressive, poorly-differentiated tumors. Most typical carcinoid tumors originate in the central airway and present with symptoms related to bronchial obstruction. In contrast, atypical carcinoids tend to occur more peripherally and are generally detected incidentally as a solitary pulmonary nodule (SPN). Typical carcinoid tumors usually do not exhibit increased metabolic activity on positron emission tomography with 18-fuorine-fluorodeoxyglucose (FDG PET) as would be expected for malignant tumors...
December 28, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29280085/usefulness-of-a-single-assay-chemiluminescence-test-tularaemia-virclia-igg%C3%A2-%C3%A2-igm-monotest-for-the-diagnosis-of-human-tularemia-comparison-of-five-serological-tests
#20
África Cubero, Carlos Durántez, Ana Almaraz, Luis Fernández-Lago, María P Gutiérrez, María J Castro, Miguel A Bratos, María Simarro, Gabriel A March, Antonio Orduña
The aim of this work was to ascertain the usefulness of a new commercially-available single-assay chemiluminescence test (CHT) for the diagnosis of human tularemia (Tularaemia VIRCLIA IgG + IgM monotest, Vircell, Santa Fe, Granada, Spain). A total of 773 sera from 773 patients including 364 initial sera from patients with diagnosed tularemia, patients with suspected tularemia not confirmed (100), healthy people (152), patients with serology positive to Brucella (97), patients diagnosed with other infectious diseases (30), and patients diagnosed with autoimmune diseases (30) were included...
December 27, 2017: European Journal of Clinical Microbiology & Infectious Diseases
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