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Youngok Kang, Nahye Cho, Serin Son
The purpose of this study is to analyze how the spatiotemporal characteristics of traffic accidents involving the elderly population in Seoul are changing by time period. We applied kernel density estimation and hotspot analyses to analyze the spatial characteristics of elderly people's traffic accidents, and the space-time cube, emerging hotspot, and space-time kernel density estimation analyses to analyze the spatiotemporal characteristics. In addition, we analyzed elderly people's traffic accidents by dividing cases into those in which the drivers were elderly people and those in which elderly people were victims of traffic accidents, and used the traffic accidents data in Seoul for 2013 for analysis...
2018: PloS One
Tony Sheldon
No abstract text is available yet for this article.
May 10, 2018: BMJ: British Medical Journal
Ansgar Thomas Kirk, Tim Kobelt, Hauke Spehlbrink, Stefan Zimmermann
Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ions are formed from the reactant ions. In this work, we present a simple yet sufficiently accurate model for predicting the ion current available at the end of this reaction region when operating at reduced pressure as in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) or most IMS-MS instruments...
May 8, 2018: Journal of the American Society for Mass Spectrometry
Steven H Brown, Russel Edge, John Elmer, Michael McDonald
Thousands of former uranium mining sites in the United States, primarily in the southwestern states of Colorado, Arizona, New Mexico, Arizona, and Utah, are being identified and evaluated to assess their potential for causing public and environmental impacts. The common radiological contaminant of concern that characterizes these sites is naturally occurring uranium ore and associated wastes that may have been left behind postmining. The majority of these sites were abandoned and in general, are referred to as abandoned uranium mines, regardless of the government authority currently managing the land or in some cases, assigned responsibility for the oversight of assessment and remediation...
June 2018: Health Physics
Billy Kenber
No abstract text is available yet for this article.
January 1, 2018: Medico-legal Journal
Ryan Hyde, Julian Chung, Jason Chertoff, Hassan Alnuaimat, Ali Ataya
A 77-year-old woman presented to the hospital with symptoms of progressive shortness of breath with associated right-sided pleuritic pain. The patient had begun noting dyspnea on exertion, limiting her ability to go on hikes over the few days prior to admission. Her medical history is significant for carcinoid tumor status postresection in 2012 without recurrence. She has no history of thromboembolism or clotting disorders, and she has no history of smoking or drug abuse. Current medications include amlodipine, celecoxib, hydrochlorothiazide, and rosuvastatin...
April 2018: Chest
Ansgar Thomas Kirk, Denise Grube, Tim Kobelt, Cornelius Wendt, Stefan Zimmermann
High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) allows for sensitive trace gas analysis within seconds, mitigating many disadvantages of standard ion mobility spectrometers through operation at reduced pressure and high electric field strengths. However, these advantages usually come at the cost of reduced resolving power, ranging from a maximum of 75 down to 50 at a reduced field strength of 120 Td for the original device. In this work, we present an extended theory for HiKE-IMS resolving power and a novel tri-state ion shutter principle able to achieve initial ion packet widths of 1 µs without significant mobility discrimination...
April 6, 2018: Analytical Chemistry
Martin Burtscher, Michael Philadelphy, Hannes Gatterer, Johannes Burtscher, Rudolf Likar
Annually, thousands of air travellers visit high altitude destinations to enjoy hiking tours to attractions in surrounding areas. However, many of them are not adequately trained, not sufficiently acclimatized and/or may suffer from pre-existing diseases. To prevent adverse health effects and unpleasant experiences at high altitude, simple submaximal exercise testing at low altitude for the prediction of exercise tolerance at high altitude would be helpful. Therefore, 40 healthy males and females performed submaximal exercise tests at low (600 m) and high altitude (3500 m)...
January 1, 2018: Journal of Travel Medicine
Norman Maldonado, Blanca Amalia Llorente, Roberto Magno Iglesias, Diego Escobar
BACKGROUND: By 2016, tobacco industry provided the only illicit trade estimates in Colombia and used these to discourage tax increases since the 1990s. To establish the viability of a threefold hike in the excise tax, policy makers needed unbiased estimates of the illicit cigarette. OBJECTIVE: To estimate the size of illicit cigarette trade in five Colombian cities (63% of the market), analyse characteristics of smokers of illicit cigarettes and compare market share results with one industry-funded survey...
March 14, 2018: Tobacco Control
Johan A de Bruijn, Aniek P M van Zantvoort, Michiel B Winkes, Marike van der Cruijsen-Raaijmakers, Adwin R Hoogeveen, Joep A W Teijink, Marc R M Scheltinga
Background: Lower leg chronic exertional compartment syndrome (CECS) is usually diagnosed in young and athletic individuals. The presence of CECS in older patients has received little attention in the literature, and patient characteristics are unknown. Purpose: To determine the prevalence of CECS in older patients (≥50 years) and to assess whether older patients with CECS differ clinically from younger patients with CECS. Study Design: Cohort study; Level of evidence, 3...
March 2018: Orthopaedic Journal of Sports Medicine
Bongjeong Kim, Hye Sun Hyun
Objectives: This study investigates investigated the relationship between social and physical environments, and moderate to vigorous physical activity (MVPA) amongst adults in both rural and urban areas within Korea. Methods: A sample of 128,735 adults from the 2013 Community Health Survey (CHS) was analyzed using a multilevel logistic analysis. Results: Urban residents with higher satisfaction in public transportation satisfaction and rural residents with more access to sports parks, hiking trails, and bike cycle paths were more likely to be active...
January 2018: Osong Public Health and Research Perspectives
Maxim V Kiryukhin, Hooi Hong Lau, Seok Hong Goh, Cathleen Teh, Vladimir Korzh, Anton Sadovoy
A new Membrane Film Sensor (MFS) has been developed to measure pH of fluids. MFS comprises a polyelectrolyte multilayer film with uniformly distributed compartments (microchambers) where a fluorescent sensing dye is encapsulated. Fabricated film is sealed onto a polyethylene film for a future use. MFS was applied to report changes in golden pomfret fillet upon its storage at 5 °C. MFS pH readings were correlated to bacteriological analysis of fish samples. A hike in pH of fish juices happens after 10 days of storage signaling bacterial spoilage of fish...
May 15, 2018: Talanta
Mirco Lo Presti, Giuseppe Gianluca Costa, Sergio Cialdella, Giuseppe Agrò, Alberto Grassi, Silvio Caravelli, Massimiliano Mosca, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini
Unicompartmental knee arthroplasty (UKA) has increased in popularity in the last years, also in younger and more active patients with great expectancies. The purpose of our study was to investigate the change in sports activities before and after medial UKA. We surveyed 53 athletic patients; all underwent cemented medial UKA, to determine not only their subjective and objective evaluation of clinical status with Hospital for Special Surgery (HSS) and visual analog score (VAS) score, but also their sporting and recreational activities at a mean follow-up of 48 ± 6 months (range, 18-56 months)...
February 28, 2018: Journal of Knee Surgery
Mariève Pouliot, Dipesh Pyakurel, Carsten Smith-Hall
ETHNOPHARMACOLOGICAL RELEVANCE: Ophiocordyceps sinensis (Berk.) G.H.Sung, J.M.Sung, Hywel-Jones & Spatafora, a high altitude Himalayan fungus-caterpillar product found in alpine meadows in China, Bhutan, Nepal, and India, has been used in the Traditional Chinese Medicine system for over 2000 years. Heightened demand in China over the past 15 years, coupled with limited production, has led to a price hike and increased economic importance of harvests to rural households throughout the species' range...
May 23, 2018: Journal of Ethnopharmacology
Deborah R Liptzin, Steven H Abman, Ann Giesenhagen, D Dunbar Ivy
Liptzin, Deborah R., Steven H. Abman, Ann Giesenhagen, and D. Dunbar Ivy. An approach to children with pulmonary edema at high altitude. High Alt Med Biol. 19:91-98, 2018. INTRODUCTION: Diagnosis of high-altitude illness can be more challenging in children, especially those who are preverbal. Families often travel to high elevations for family vacations, either for skiing, hiking, and/or camping. They may present to their primary care providers looking for anticipatory guidance before travel or may follow-up after developing high-altitude illness...
March 2018: High Altitude Medicine & Biology
Roxanne Nelson
No abstract text is available yet for this article.
February 2018: Lancet Infectious Diseases
Bassey Enya Bassey, Fiona Braka, Rui Gama Vaz, William Komakech, Sylvester Toritseju Maleghemi, Richard Koko, Thompson Igbu, Faith Ireye, Sylvester Agwai, Godwin Ubong Akpan, Sisay Gashu Tegegne, Abdul-Aziz Garba Mohammed, Angela Okocha-Ejeko
BACKGROUND: The globally synchronized switch from trivalent Oral Polio Vaccine (tOPV) to bivalent Oral Polio Vaccine (bOPV) took place in Nigeria on April 18th 2016. The country is divided into six geopolitical zones. This study reports the experiences and lessons learned from the switch process in the six states that make up Nigeria's south-south geopolitical zone. METHODS: This was a descriptive retrospective review of Nigeria's switch plan and structures used for implementing the tOPV-bOPV switch in the south-south zone...
January 27, 2018: BMC Infectious Diseases
Michel Zeitouni, Mathieu Kerneis, Tarek Nafee, Jean-Philippe Collet, Johanne Silvain, Gilles Montalescot
Early intravenous anticoagulation is the corner stone treatment of patients admitted with an acute coronary syndrome: it antagonizes the ongoing coronary thrombosis and facilitates the percutaneous coronary intervention, hence a reduction of mortality and acute stent thrombosis. Unfractionated heparin, enoxaparin, bivalirudin and fondaparinux have been extensively studied in large randomized control trials and meta-analyses with the same objective: reducing the ischemic burden without hiking hemorrhagic events...
January 2018: Progress in Cardiovascular Diseases
Stephen Barlas
Is industry consolidation a response to President Donald Trump's repeated denunciation of high drug prices and congressional hearings on the issue? The author considers whether any of this corporate collaboration will get at some of the significant, underlying problems in the drug-pricing space.
January 2018: P & T: a Peer-reviewed Journal for Formulary Management
Zhanju Yang, Qiao Wang, Ke Ma, Ping Shi, Wenbin Liu, Zhiwei Huang
OBJECTIVES: The study aims to explore the synergistically antifungal mechanism of fluconazole and berberine. METHODS: Biochemical and genetic analysis was performed to investigate the probable antifungal role of the combined use of berberine and fluconazole in Saccharomyces cerevisiae, a typical fungal cell model. RESULTS: Fluconazole led to an elevated cell membrane permeability in the wild type yeast BY4741, similar as the sterol synthesis deficient strains erg2Δ and erg6Δ...
December 26, 2017: Journal of Global Antimicrobial Resistance
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