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https://www.readbyqxmd.com/read/29798755/-haemorrhagic-proctocolitis-as-primary-manifestation-of-lymphogranuloma-venereum-in-an-hiv-positive-male
#1
Andreas Brandt Gormsen, Jon Erik Fraes Diernæs, Jørgen Skov Jensen, Uffe Koppelhus
This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. LGV is a se xually transmitted infection with a rising incidence among persons with risk behaviour. This case report underlines the importance, that all positive rectal screenings for Chlamydia trachomatis should be routinely serotyped...
May 14, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29795388/left-gastric-vein-based-noninvasive-test-for-esophageal-varices-a-same-day-comparison-of-portal-hemodynamic-assessment-with-endoscopic-appearance
#2
Hitoshi Maruyama, Kazufumi Kobayashi, Soichiro Kiyono, Sadahisa Ogasawara, Yoshihiko Ooka, Eiichiro Suzuki, Tetsuhiro Chiba, Naoya Kato
OBJECTIVE: To examine the effect of hemodynamic assessment of the left gastric vein (LGV) as a noninvasive test to diagnose esophageal varices (EV) in cirrhosis patients. METHODS: This cross-sectional study consisted of 229 cirrhosis patients (62.7 ± 11.8 years; Child-Pugh score 5-14). One hundred fifty-four patients had EV (67.2%; small, 53; medium, 71; large, 30). All patients underwent a blood test and Doppler ultrasound followed by upper gastrointestinal endoscopy on the same day...
May 25, 2018: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/29770100/lymphogranuloma-venereum-in-quebec-re-emergence-among-men-who-have-sex-with-men
#3
C A Boutin, S Venne, M Fiset, C Fortin, D Murphy, A Severini, C Martineau, J Longtin, A C Labbé
Background: Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis genotypes L1 , L2 and L3 . This LGV is associated with significant morbidity and increased risk of HIV transmission. While fewer than two cases per year were reported in Quebec before 2005, LGV emerged in 2005-2006 with 69 cases, followed by a period of low incidence (2007-2012), and subsequent re-emergence since 2013. Objectives: To describe the incidence of LGV in Quebec and the characteristics of the affected population, including demographics and risk factors, clinical manifestations, laboratory tests, treatments and reinfection rates...
February 1, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29749879/lymphogranuloma-venereum-a-rare-and-forgotten-cause-of-rectal-stricture-formation
#4
Leia Craxford, Ashini Fox
Lymphogranuloma venereum (LGV) is caused by L1, L2 and L3 serovars of Chlamydia trachomatis. The anorectal syndrome caused by LGV is often misdiagnosed as inflammatory bowel disease and may rarely lead to stricture formation. Recurrent stricture formation, despite adequate LGV treatment, has not to our knowledge, previously been reported.
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29722270/proctitis-and-perirectal-abscesses-is-there-anything-else-to-think-about
#5
Alicia Martín-Lagos Maldonado, Myriam Del Carmen Herrera Mercader, Cristina Lozano Cejudo
Lymphogranuloma venereum (LGV) is a condition caused by invasive serovars of Chlamydia trachomatis. The classical inguinal presentation that is characterized by the development of transient genital ulcer(s) and inguinal or femoral lymphadenopathy has decreased in our environment. At present, infection by this bacterium has emerged as an important cause of proctitis and proctocolitis in men who have sex with other men. We report the case of a homosexual man with acute proctitis that was complicated by a perirectal abscess secondary to a Chlamydia trachomatis infection...
May 3, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29680458/sexually-transmitted-diseases-of-the-anus-and-rectum-causal-agents-coinfections-hiv-infection-and-high-risk-sexual-behaviour
#6
Daniel Morgado-Carrasco, Mercè Alsina Gibert, Jordi Bosch Mestres, Miriam Álvarez Martínez, José Luís Blanco Arévalo, Irene Fuertes de Vega
INTRODUCTION AND OBJECTIVE: Sexually transmitted infections of the rectum and anus (STI-RA) mainly affect men who have sex with men (MSM). The incidence of STI-RA among them has increased in recent years. MATERIAL AND METHODS: Retrospective study in patients with diagnoses of STI-RA in an STI unit during the years 2014 and 2015. Epidemiological, clinical and microbiological data were collected. RESULTS: We included 95 patients, all of whom were MSM; 88...
April 18, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29667379/lymphogranuloma-venereum-genovar-l2b-concomitantly-with-syphilis-and-hepatitis-c-in-a-male-patient-in-poland-%C3%A2-case-report
#7
Agnieszka Beata Serwin, Marta Koper, Magnus Unemo
We describe the first case of lymphogranuloma venereum (LGV) in Poland, with inguino-femoral lymphadenopathy, diagnosed and successfully treated according to the 2013 European LGV guideline. Chlamydia trachomatis genovar L2b, mainly responsible for the ongoing LGV epidemics among men who have sex with men (MSM) in Western European countries, was confirmed. The case also verified that co-infections with other sexually transmitted infections (syphilis and hepatitis C virus) are frequent in MSM LGV patients, as well as the very large difficulties with contact tracing for these patients...
2018: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/29617372/trends-in-the-relative-prevalence-of-genital-ulcer-disease-pathogens-and-association-with-hiv-infection-in-johannesburg-south-africa-2007-2015
#8
Ranmini S Kularatne, Etienne E Muller, Dumisile V Maseko, Tendesayi Kufa-Chakezha, David A Lewis
BACKGROUND: In South Africa, treatment of genital ulcer disease (GUD) occurs in the context of syndromic management. GUD aetiological studies have been conducted in Johannesburg since 2007. We report on GUD pathogen prevalence, sero-prevalence of STI co-infections and aetiological trends among GUD patients presenting to a community-based primary healthcare facility in Johannesburg over a 9-year period. METHODS AND FINDINGS: GUD surveys were conducted from January to April each year...
2018: PloS One
https://www.readbyqxmd.com/read/29560668/lymphogranuloma-venereum-among-patients-presenting-at-the-hiv-sti-clinic-in-antwerp-belgium-a-case-series
#9
Ludwig Apers, Eric Florence, Tania Crucitti, Nabila Anwar
Objective of this study was to describe the patient characteristics and clinical presentation of laboratory confirmed lymphogranuloma venereum (LGV) cases, diagnosed at the Institute of Tropical Medicine (ITM), Antwerp, Belgium. Demographic and biomedical characteristics of all patients with chlamydia-positive sample results were retrieved for the years 2013 and 2014. Samples were obtained from both symptomatic and asymptomatic patients who consulted at the HIV/STI clinic. Fifty four patients with laboratory confirmed LGV were detected among 3885 nucleic acid amplification tests (NAATs) performed for the detection of chlamydia during the two years under review...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29555864/proctocolitis-caused-by-lymphogranuloma-venereum
#10
Edward Weiss, Marie Sano
No abstract text is available yet for this article.
March 19, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29553338/chlamydia-trachomatis-in-cervical-lymph-node-of-man-with-lymphogranuloma-venereum-croatia-2014-1
#11
Branimir Gjurašin, Snježana Židovec Lepej, Michelle J Cole, Rachel Pitt, Josip Begovac
We report an HIV-infected person who was treated for lymphogranuloma venereum cervical lymphadenopathy and proctitis in Croatia in 2014. Infection with a variant L2b genovar of Chlamydia trachomatis was detected in a cervical lymph node aspirate. A prolonged course of doxycycline was required to cure the infection.
April 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29545442/unusual-case-of-a-rectal-tumour
#12
Maryam Alfa-Wali, Samantha Muktar, Dimitrios Pissas, Ceri Slater
A 48-year-old man presented as an emergency with a 3-week history of rectal bleeding. Examination of his rectum revealed a circumferential tumour, 2 cm from the anal verge. An MRI scan reported a locally infiltrative mid-lower rectal tumour staged as T3d/T4 N2 MX. A colonoscopy revealed appearances of severe proctitis and biopsies did not show any evidence of dysplasia or malignancy. The patient was discussed at the regional colorectal cancer multidisciplinary team meeting with a management plan for neoadjuvant chemoradiotherapy following repeat biopsies, which were again negative for malignancy...
March 15, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29530239/-haemorrhagic-proctocolitis-as-primary-manifestation-of-lymphogranuloma-venereum-in-an-hiv-positive-male
#13
Andreas Brandt Gormsen, Jon Erik-Fraes Diernæs, Jørgen Skov Jensen, Uffe Koppelhus
This is a case report of lymphogranuloma venereum (LGV) manifesting as haemorrhagic proctocolitis in a homosexual HIV-positive male. The primary symptom was a rectal abscess, which was initially surgically treated and subsequently insufficiently treated with single-dose tablet azithromycin. The patient's symptoms were successfully treated after a 21-day doxycycline regime. LGV is a sexually transmitted infection with a rising incidence among persons with risk behaviour. This case report underlines the importance, that all positive rectal screenings for Chlamydia trachomatis should be routinely serotyped...
March 12, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29513173/lymphogranuloma-venereum-among-patients-presenting-at-the-hiv-sti-clinic-in-antwerp-belgium-a-case-series
#14
L Apers, E Florence, T Crucitti, N Anwar
Objective of this study was to describe the patient characteristics and clinical presentation of laboratory confirmed lymphogranuloma venereum (LGV) cases, diagnosed at the Institute of Tropical Medicine (ITM), Antwerp, Belgium. Demographic and biomedical characteristics of all patients with chlamydia-positive sample results were retrieved for the years 2013 and 2014. Samples were obtained from both symptomatic and asymptomatic patients who consulted at the HIV/STI clinic. Fifty four patients with laboratory confirmed LGV were detected among 3885 nucleic acid amplification tests (NAATs) performed for the detection of chlamydia during the two years under review...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29465660/observed-treatment-responses-to-short-course-doxycycline-therapy-for-rectal-lymphogranuloma-venereum-lgv-in-men-who-have-sex-with-men
#15
Rebecca Simons, Sophie Candfield, Patrick French, John A White
BACKGROUND: Lymphogranuloma venereum (LGV) has re-established itself as an endemic sexually transmitted infection (STI) in the UK and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including its duration is very limited. METHODS: We conducted a retrospective review in two central London genitourinary medicine (GUM) clinics of men who have sex with men (MSM) with LGV in whom less than 21 days of doxycycline was used initially...
December 7, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29382731/plasmid-negative-regulation-of-cpaf-expression-is-pgp4-independent-and-restricted-to-invasive-chlamydia-trachomatis-biovars
#16
Michael John Patton, Chih-Yu Chen, Chunfu Yang, Stuart McCorrister, Chris Grant, Garrett Westmacott, Xin-Yong Yuan, Estela Ochoa, Robert Fariss, William M Whitmire, John H Carlson, Harlan D Caldwell, Grant McClarty
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease. C. trachomatis isolates are classified into 2 biovars-lymphogranuloma venereum (LGV) and trachoma-which are distinguished biologically by their natural host cell infection tropism. LGV biovars infect macrophages and are invasive, whereas trachoma biovars infect oculo-urogenital epithelial cells and are noninvasive. The C. trachomatis plasmid is an important virulence factor in the pathogenesis of these infections...
January 30, 2018: MBio
https://www.readbyqxmd.com/read/29378902/asymptomatic-lymphogranuloma-venereum-among-nigerian-men-who-have-sex-with-men
#17
Trevor A Crowell, Justin Hardick, Kara Lombardi, Zahra Parker, Afoke Kokogho, Senate Amusu, Sunday Odeyemi, Andrew Ivo, Stefan D Baral, Rebecca G Nowak, Sylvia Adebajo, Manhattan E Charurat, Julie Ake, Charlotte A Gaydos
OBJECTIVES: Recent outbreaks of anorectal lymphogranuloma venereum (LGV) among men who have sex with men (MSM) have been characterised by proctocolitis requiring extended antibiotic treatment compared with infections caused by other serovars of Chlamydia trachomatis (CT). We describe the prevalence and clinical features of LGV among Nigerian MSM diagnosed with anorectal CT. METHODS: MSM were recruited for this observational cohort in Lagos, Nigeria, using respondent-driven sampling and screened for HIV and bacterial STIs every three months for up to 18 months...
January 29, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29353997/left-gastric-vein-visualization-with-hepatopetal-flow-information-in-healthy-subjects-using-non-contrast-enhanced-magnetic-resonance-angiography-with-balanced-steady-state-free-precession-sequence-and-time-spatial-labeling-inversion-pulse
#18
Akihiro Furuta, Hiroyoshi Isoda, Tsuyoshi Ohno, Ayako Ono, Rikiya Yamashita, Shigeki Arizono, Aki Kido, Naotaka Sakashita, Kaori Togashi
Objective: To selectively visualize the left gastric vein (LGV) with hepatopetal flow information by non-contrast-enhanced magnetic resonance angiography under a hypothesis that change in the LGV flow direction can predict the development of esophageal varices; and to optimize the acquisition protocol in healthy subjects. Materials and Methods: Respiratory-gated three-dimensional balanced steady-state free-precession scans were conducted on 31 healthy subjects using two methods (A and B) for visualizing the LGV with hepatopetal flow...
January 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29350113/asymptomatic-urethral-lymphogranuloma-venereum-a-case-report
#19
Louise Charest, Judith Fafard, Zoë R Greenwald
Since 2003, there has been a resurgence of lymphogranuloma venereum (LGV), a variant of Chlamydia trachomatis (CT), among men who have sex with men (MSM) in several urban areas of Europe and North America. LGV infection occurs most often at anal sites causing proctitis. Urethral and oropharyngeal infections are rare. In Quebec, LGV incidence has been increasing exponentially in recent years and the current guidelines support systematic LGV genotype testing among anorectal CT-positive samples only. This case report describes a patient with a urethral LGV infection, remarkable due to its prolonged asymptomatic development prior to the manifestation of an inguinal bubo...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29240636/the-etiology-of-genital-ulcer-disease-and-coinfections-with-chlamydia-trachomatis-and-neisseria-gonorrhoeae-in-zimbabwe-results-from-the-zimbabwe-sti-etiology-study
#20
More Mungati, Anna Machiha, Owen Mugurungi, Mufuta Tshimanga, Peter H Kilmarx, Justice Nyakura, Gerald Shambira, Vitalis Kupara, David A Lewis, Elizabeth Gonese, Beth A Tippett Barr, H Hunter Handsfield, Cornelis A Rietmeijer
BACKGROUND: In many countries, sexually transmitted infections (STIs) are treated syndromically. Thus, patients diagnosed as having genital ulcer disease (GUD) in Zimbabwe receive a combination of antimicrobials to treat syphilis, chancroid, lymphogranuloma venereum (LGV), and genital herpes. Periodic studies are necessary to assess the current etiology of GUD and assure the appropriateness of current treatment guidelines. MATERIALS AND METHODS: We selected 6 geographically diverse clinics in Zimbabwe serving high numbers of STI cases to enroll men and women with STI syndromes, including GUD...
January 2018: Sexually Transmitted Diseases
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