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JOURNAL ARTICLE
Abdulrahman Hakami, Tahani Altubayqi, Entsar A Qadah, Basem Zogel, Samar M Alfaifi, Eman Refaei, Ahmed Sayed, Luai Alhazmi, Maram Sayegh, Abdullah Alamer, Areej S Areeshi, Duaa Hakami
Background COVID-19 is a major cause of illness and mortality. The management of COVID-19-related illnesses might change if variables connected to their severity and the requirement for ICU admission could be found. The severity of COVID-19 might be efficiently predicted with several laboratory measures, such as ferritin levels and D-dimer analysis. Objectives This study aimed to evaluate the association between serum D-dimer and ferritin levels and their effects on mortality in patients with COVID-19. Methods This retrospective observational study included all patients with positive real-time polymerase chain reaction (RT-PCR) results for COVID-19 who were hospitalized in the Ministry of Health South Al-Qunfudah General Hospital between March and September 30, 2020...
September 2023: Curēus
#22
JOURNAL ARTICLE
I Yıldırım, C Aydın, A Gültekin, M T İnal, D Memiş
OBJECTIVE: Prone positioning has been found to improve oxygenation in most patients with acute respiratory distress syndrome (ARDS). The study aimed to investigate the effectiveness of the prone position in patients with ARDS. PATIENTS AND METHODS: The prone position is one of the ventilator techniques included in recent guidelines for acute respiratory distress syndrome. This study was a retrospective evaluation of the records of 100 ARDS patients who were administered prone position mechanical ventilation in our intensive care unit...
October 2023: European Review for Medical and Pharmacological Sciences
#23
JOURNAL ARTICLE
Gunjan Kumar, Ashish Bhalla, Aparna Mukherjee, Alka Turuk, Arunansu Talukdar, Subhasis Mukherjee, Pankaj Bhardwaj, Geetha R Menon, Damodar Sahu, Puspender Misra, Lokesh Kumar Sharma, Ritin Mohindra, Samita S, Vikas Suri, Himadri Das, Debasis Sarkar, Soumyadeep Ghosh, Priyanka Ghosh, Moumita Dutta, Shreetama Chakraborty, Deepak Kumar, Manoj Kumar Gupta, Akhil Dhanesh Goel, Tridip Dutta Baruah, Pankaj Kumar Kannauje, Arvind Kumar Shukla, Janakkumar R Khambholja, Amit Patel, Nitesh Shah, Sourin Bhuniya, Manoj Kumar Panigrahi, Prasanta Raghab Mohapatra, Ashish Pathak, Ashish Sharma, Mary John, Kiranpreet Kaur, Vijay Nongpiur, Star Pala, Sachin K Shivnitwar, Bobba Rohil Krishna, Naveen Dulhani, Balkishan Gupta, Jigyasa Gupta, Sudhir Bhandari, Abhishek Agrawal, H K Aggarwal, Deepak Jain, Arti D Shah, Parshwa Naik, Manisha Panchal, Mayank Anderpa, Nyanthung Kikon, Christina Nzani Humtsoe, Nikita Sharma, Rajaat Vohra, Lipilekha Patnaik, Jagdish Prasad Sahoo, Rajnish Joshi, Arun Kokane, Yogiraj Ray, Kruti Rajvansh, Hemang M Purohit, Nehal M Shah, Arun Madharia, Simmi Dube, Neha Shrivastava, Sushila Kataria, Mohammad Shameem, Nazish Fatima, Saumitra Ghosh, Avijit Hazra, Himanshu D, Veeresh B Salgar, Santosh Algur, Kala Yadhav M L, Pavan Kumar M, Samiran Panda, Mendu Vishnu Vardhana Rao, Balram Bhargava
INTRODUCTION: The effects of COVID-19 infection persist beyond the active phase. Comprehensive description and analysis of the post COVID sequelae in various population groups are critical to minimise the long-term morbidity and mortality associated with COVID-19. This analysis was conducted with an objective to estimate the frequency of post COVID sequelae and subsequently, design a framework for holistic management of post COVID morbidities. METHODS: Follow-up data collected as part of a registry-based observational study in 31 hospitals across India since September 2020-October 2022 were used for analysis...
October 2023: BMJ Global Health
#24
JOURNAL ARTICLE
Snigdha Jain, Ling Han, Evelyne A Gahbauer, Linda Leo-Summers, Shelli L Feder, Lauren E Ferrante, Thomas M Gill
RATIONALE: Survivors of critical illness have multiple symptoms, but how restricting symptoms change after critical illness and whether these changes differ among vulnerable subgroups is unknown. OBJECTIVE: To evaluate changes in restricting symptoms over the six months after critical illness among older adults and to determine whether these changes differ by sex, multimorbidity, individual- and neighborhood-level socioeconomic disadvantage. METHODS: From a prospective longitudinal study of 754 community-living adults≥70 years old interviewed monthly (1998-2018), we identified 233 admissions from 193 participants to the intensive care unit (ICU)...
September 28, 2023: American Journal of Respiratory and Critical Care Medicine
#25
JOURNAL ARTICLE
A J Y Chan, K C Lung, J S Y Yu, H P Shum, T Y Tsang
INTRODUCTION: In 2020, patients with critical coronavirus disease 2019 (COVID-19) had a 28-day mortality rate of 30% to 50% worldwide; outcomes among such patients in Hong Kong were unknown. This study investigated 28-day mortality and corresponding risk factors among patients with severe or critical COVID-19 in Hong Kong. METHODS: This retrospective cohort study included adult patients with severe or critical COVID-19 who were admitted to three public hospitals in Hong Kong from 22 January to 30 September 2020...
September 28, 2023: Hong Kong Medical Journal
#26
REVIEW
Qifa Wang, Fen Liu, Wenqiang Tao, Kejian Qian
OBJECTIVE: The objective of this study was to evaluate the clinical efficacy of early and delayed renal replacement therapy (RRT) in patients with sepsis-associated acute kidney injury (AKI). METHODS: We searched three databases (PubMed, Web of Science, and Cochrane) for randomised controlled trials and cohort studies published up to March 28, 2022, and manually searched for relevant references. We included data from adults older than 18 years of age with sepsis-associated AKI...
September 19, 2023: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
#27
JOURNAL ARTICLE
Cecilia Gonzalez, Gabriel Musso, Jesica Rodriguez Louzan, Juan Manuel Dominguez, Celeste Gomez, Gabriel Appendino, Analía Abaca, Lucio Clemente, Diana Latasa, Martin Manago, Carlos Lovesio, Elisa Estenssoro
OBJECTIVE: To analyze characteristics, changes in oxygenation, and pulmonary mechanics, in mechanically ventilated patients with ARDS due to SARS-CoV-2 treated with prone position and evaluate the response to this maneuver. DESIGN: Cohort study including patients with PaO2 /FiO2 <150mmHg requiring prone position over 18 months. We classified patients according to PaO2 /FiO2 changes from basal to 24h after the first prone cycle as: 1) no increase 2) increase <25%, 3) 25%-50% increase 4) increase >50%...
September 13, 2023: Medicina intensiva
#28
JOURNAL ARTICLE
Ali Ait Hssain, Nicolas Farigon, Hamid Merdji, Dominique Guelon, Julien Bohé, Sophie Cayot, Russel Chabanne, Jean-Michel Constantin, Bruno Pereira, Damien Bouvier, Nicolas Andant, Hubert Roth, Ronan Thibault, Vincent Sapin, Michel Hasselmann, Bertrand Souweine, Noël Cano, Yves Boirie, Claire Dupuis
BACKGROUND & AIMS: After a prolonged intensive care unit (ICU) stay patients experience increased mortality and morbidity. The primary aim of this study was to assess the prognostic value of nutritional status, body mass composition and muscle strength, as assessed by body mass index (BMI), bioelectrical impedance analysis (BIA), handgrip (HG) test, and that of the biological features to predict one-year survival at the end of a prolonged ICU stay. METHODS: This was a multicenter prospective observational study...
October 2023: Clinical Nutrition
#29
JOURNAL ARTICLE
Mina Mondal, Muhammad Nazrul Islam, Ahsan Ullah, Md Rezwanul Haque, Motiur Rahman, Liza Bosak, Md Foyzur Rahman, Shaikh Riaduz Zaman, Mohammad Meshbahur Rahman
INTRODUCTION: The outbreak of COVID-19 poses great challenges for patients on maintenance haemodialysis. Here, we reported the clinical characteristics and laboratory features of maintenance haemodialysis (MHD) patients with COVID-19 in Bangladesh. METHODS: Altogether, 67 MHD patients were enroled in the study from two dedicated tertiary-level hospitals for COVID-19 after the prospective cross-sectional execution of selection criteria. Data were collected from medical records and interviews...
September 2023: Annals of Medicine and Surgery
#30
JOURNAL ARTICLE
Kamal Kajal, Karan Singla, Goverdhan Dutt Puri, Ashish Bhalla, Aparna Mukherjee, Gunjan Kumar, Alka Turuk, Madhumita Premkumar, Varun Mahajan, Naveen B Naik, Thrilok Chander Bingi, Pankaj Bhardwaj, Mary John, Geetha R Menon, Damodar Sahu, Samiran Panda, Vishnu Vardhan Rao
BACKGROUND: Patients admitted to intensive care units (ICUs) with severe coronavirus disease (COVID-19) are associated with high mortality. The present retrospective, multicenter study describes the predictors and outcomes of COVID-19 patients requiring ICU admission from COVID-19 Registry of Indian Council of Medical Research (ICMR), India. MATERIALS AND METHODS: Prospectively collected data from participating institutions were entered into the electronic National Clinical Registry of COVID-19...
August 2023: Indian Journal of Critical Care Medicine
#31
JOURNAL ARTICLE
Kwok M Ho, David J Morgan, Mason Johnstone, Cyrus Edibam
Biological age is increasingly recognized as being more accurate than chronological age in determining chronic health outcomes. This study assessed whether biological age, assessed on intensive care unit (ICU) admission, can predict hospital mortality. This retrospective cohort study, conducted in a tertiary multidisciplinary ICU in Western Australia, used the Levine PhenoAge model to estimate each patient's biological age (also called PhenoAge). Each patient's PhenoAge was calibrated to generate a regression residual which was equivalent to biological age unexplained by chronological age in the local context...
August 28, 2023: Internal and Emergency Medicine
#32
JOURNAL ARTICLE
Seung Hye Lee, Chan Hee Kim, Hee Young Lee, Kun Hee Park, Su Ha Han
The incidence of carbapenem-resistant Enterobacteriaceae (CRE) has been increasing since 2008, with Gyeonggi Province in South Korea being particularly vulnerable due to its large number of healthcare facilities. This study examines the trends of CRE occurrence in Gyeonggi Province over the past four years and the epidemiological characteristics of the infected patients. Patients with positive CRE blood cultures admitted to healthcare facilities in Gyeonggi Province from January 2018 to December 2021 were evaluated in this study...
August 4, 2023: Antibiotics
#33
JOURNAL ARTICLE
Sophia Wang, Anthony J Perkins, Rosalyn Chi, Brandon A Yates, Sikandar H Khan, Sujuan Gao, Malaz Boustani, Babar A Khan
INTRODUCTION: As the number of older intensive care unit (ICU) survivors grows, there is an urgent need to identify modifiable risk factors for post-ICU dementia. METHODS: We performed a secondary data analysis of 3144 ICU patients ≥ 50 years of age without a history of dementia or severe mental illness who were screened as part of the Pharmacological Management of Delirium (PMD) study. Delirium was assessed using the Confusion Assessment Method for the ICU...
August 17, 2023: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
#34
JOURNAL ARTICLE
Jiyeon Kang, Kwang Min Lee
BACKGROUND: Due to the increasing number of critical care survivors, population-based studies on the long-term outcomes after discharge are necessary to inform local decision-making. OBJECTIVES: This study aimed to investigate mortality and its risk factors, readmissions, and medical expenses of intensive care unit survivors for 3 years after hospital discharge. METHODS: This retrospective study analysed data from the National Health Insurance Service-National Sample Cohort in Korea...
August 11, 2023: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
#35
JOURNAL ARTICLE
Thomas Servais, France Laurent, Thomas Roland, Camelia Rossi, Elodie De Groote, Valérie Godart, Ernestina Repetto, Michel Ponchon, Pascale Chasseur, Laurent Crenier, Sandrine Van Eeckhoudt, John Yango, Philippe Oriot, Mirela Morisca Gavriliu, Stéphanie Rouhard, Benjamin Deketelaere, Dominique Maiter, Michel Paul Hermans, Jean Cyr Yombi, Laura Orioli
BACKGROUND AND AIMS: We describe mortality-related risk factors of inpatients with diabetes and coronavirus disease 2019 (COVID-19) in Belgium. METHODS: We conducted a multicenter retrospective study from March to May, 2020, in 8 Belgian centers. Data on admission of patients with diabetes and COVID-19 were collected. Survivors were compared to non-survivors to identify prognostic risk factors for in-hospital death, using multivariate analysis in both the total population and in the subgroup of patients admitted to the intensive care unit (ICU)...
August 11, 2023: Annales D'endocrinologie
#36
JOURNAL ARTICLE
Michał Czapla, Adrian Kwaśny, Małgorzata Słoma-Krześlak, Raúl Juárez-Vela, Piotr Karniej, Sara Janczak, Aleksander Mickiewicz, Bartosz Uchmanowicz, Stanisław Zieliński, Marzena Zielińska
BACKGROUND: A number of factors influence mortality in post-cardiac-arrest (CA) patients, nutritional status being one of them. The aim of this study was to assess whether there are sex differences in the prognostic impact of BMI, as calculated on admission to an intensive care unit, on in-hospital mortality in sudden cardiac arrest (SCA) survivors. METHODS: We carried out a retrospective analysis of data of 129 post-cardiac-arrest patients with return of spontaneous circulation (ROSC) admitted to the Intensive Care Unit (ICU) of the University Teaching Hospital in Wrocław between 2017 and 2022...
August 4, 2023: Nutrients
#37
JOURNAL ARTICLE
Philip A Efron, Scott C Brakenridge, Alicia M Mohr, Evan L Barrios, Valerie E Polcz, Stephen Anton, Tezcan Ozrazgat-Baslanti, Azra Bihorac, Faheem Guirgis, Tyler J Loftus, Martin Rosenthal, Christian Leeuwenburgh, Robert Mankowski, Lyle L Moldawer, Frederick A Moore
With the implementation of new intensive care unit (ICU) therapies in the 1970s, multiple organ failure (MOF) emerged as a fulminant inflammatory phenotype leading to early ICU death. Over the ensuing decades, with fundamental advances in care, this syndrome has evolved into a lingering phenotype of chronic critical illness (CCI) leading to indolent late post-hospital discharge death. In 2012, the University of Florida (UF) Sepsis Critical Illness Research Center (SCIRC) coined the term Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS) to provide a mechanistic framework to study CCI in surgical patients...
August 8, 2023: Journal of Trauma and Acute Care Surgery
#38
JOURNAL ARTICLE
Omar A Al Omair, Abdallah Essa, Khaled Elzorkany, Somaia Shehab-Eldeen, Hamzah M Alarfaj, Sumaia M Alarfaj, Fatimah Alabdulqader, Alghaydaa Aldoughan, Mohammed Agha, Sayed I Ali, Ehab Darwish
BACKGROUND: The emerging COVID-19 coronavirus disease has widely spread, causing a serious worldwide pandemic. Disease severity and mortality risk can be predicted using an analysis of COVID-19 clinical characteristics. Finding out what influences patients' hospitalization length and in-hospital mortality is crucial for decision-making and planning for emergencies. The goal of this study is to identify the factors that influence hospital stay length and in-hospital death due to COVID-19 infection...
2023: International Journal of General Medicine
#39
JOURNAL ARTICLE
Bert B Little, Shakib Shaminul, Maria E Pena Reyes, Seyed Karimi, Giang T Vu, Natalie Dupré, W Paul McKinney, Riten Mitra
BACKGROUND: Indigenous individuals have higher rates of mortality and poverty in Mexico and more than half are marginalised, and COVID-19 pandemic aggravated the existing burden of health disparities. We aimed to analyse the effects of being indigenous and marginalised on coronavirus (COVID-19) infection fatality in Mexico. METHODS: We identified 3 424 690 non-pregnant, COVID-19 positive adults ≥19 years in the Mexico national COVID-19 database with known date of symptom...
July 28, 2023: Journal of Global Health
#40
JOURNAL ARTICLE
Hassan Ashktorab, Gholamreza Oskrochi, Suryanarayana Reddy Challa, Lakshmi G Chirumamilla, Faezeh Ahangarzadeh, Boubini Jones-Wonni, Nader Shayegh, Mudasir Rashid, Zainab Naqvi, Elizabeth Ekpe, Sen Sabyasachi, Anteneh Zenabe, Hassan Brim
BACKGROUND AND AIM: Type 2 diabetes mellitus (DM) is a common comorbidity in the minority population and is associated with poor outcomes in COVID-19 patients. We hypothesized that COVID-19 patients with pre-existing diabetes mellitus are prone to fatal outcomes compared to non-diabetic patients. We aimed to illustrate the characteristics and outcomes and identify the risk factors for in-hospital mortality of COVID-19 patients with DM. METHODS: In this single-center retrospective study, electronic medical records of hospitalized patients with confirmed COVID-19 diagnosis at Howard University Hospital (HUH) from March 2020 to Dec 2021 were analyzed...
July 27, 2023: Journal of Racial and Ethnic Health Disparities
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