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https://www.readbyqxmd.com/read/28716504/data-collection-in-pragmatic-trials
#1
Anna-Katharina Meinecke, Paco Welsing, George Kafatos, Des Burke, Sven Trelle, Maria Kubin, Gaelle Nachbaur, Matthias Egger, Mira Zuidgeest
Pragmatic trials can improve our understanding of how treatments will perform in routine practice. In a series of eight papers, the GetReal Consortium has evaluated the challenges in designing and conducting pragmatic trials and their specific methodological, operational, regulatory, and ethical implications. The present final paper of the series discusses the operational and methodological challenges of data collection in pragmatic trials. A more pragmatic data collection needs to balance the delivery of highly accurate and complete data with minimizing the level of interference that data entry and verification induce with clinical practice...
July 14, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28635575/-high-risk-obstetrics-in-tertiary-centres-anaesthetist-hybrid-operating-suite-and-obstetric-critical-care-unit
#2
C D van der Marel, A J Eggink, R J Stolker
The frequency of pregnancy-related morbidity has increased over recent decades, as has the number of patients with complex congenital cardiac anomalies reaching fertile age, resulting in an increasing number of high-risk pregnancies. In order to optimalise maternal and foetal outcome in these patients, not only is the availability of optimal in-hospital facilities (e.g. obstetric critical care unit, hybrid operating suite) important, but also a multidisciplinary approach which is mandatory for successful maternal and foetal outcome...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28515515/the-parturient-in-the-interventional-radiology-suite-new-frontier-in-obstetric-anaesthesia
#3
REVIEW
Tasneem Dhansura, Nabila Shaikh
The anaesthesiologist's presence during interventional radiology (IR) is increasing due to increasingly ill patients and intricate procedures. The management of a parturient in IR suite is complex in terms of logistics of an unfamiliar procedure in an unfamiliar area. The literature available is largely written by radiologists with little attention paid to anaesthetic details and considerations. In the Indian scenario, in the absence of hybrid operating rooms (ORs), logistics involve transport of a parturient back and forth between the IR suite and the OR...
April 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28481391/novel-hybrid-operating-table-for-neuroendovascular-treatment
#4
Park Jong-Hyun, Mun Jonghyeon, Shin Dong-Seung, Kim Bum-Tae
BACKGROUND: The integration of interventional and surgical techniques is requiring the development of a new working environment equipped for the needs of an interdisciplinary neurovascular team. However, conventional surgical and interventional tables have only a limited ability to provide for these needs. We have developed a concept mobile hybrid operating table that provides the ability for such a team to conduct both endovascular and surgical procedures in a single session. METHODS: We developed methods that provide surgeons with angiography-guided surgery techniques for use in a conventional operating room environment...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28299688/all-electrical-graphene-dna-sensor-array
#5
Jeffrey Abbott, Donhee Ham, Guangyu Xu
Electrical sensing of biomolecules has been an important pursuit due to the label-free operation and chip-scale construct such sensing modality can enable. In particular, electrical biomolecular sensors based on nanomaterials such as semiconductor nanowires, carbon nanotubes, and graphene have demonstrated high sensitivity, which in the case of nanowires and carbon nanotubes can surpass typical optical detection sensitivity. Among these nanomaterials, graphene is well suited for a practical candidate for implementing a large-scale array of biomolecular sensors, as its two-dimensional morphology is readily compatible with industry standard top-down fabrication techniques...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28282990/validation-and-accuracy-of-intraoperative-ct-scan-using-the-philips-alluraxper-fd20-angiography-suite-for-assessment-of-spinal-instrumentation
#6
Edin Nevzati, Javier Fandino, Bawarjan Schatlo, Michel Heimberg, Serge Marbacher, Luca Remonda, Ali-Reza Fathi
BACKGROUND: With the concept of the hybrid operating room gaining popularity, the authors adapted a hybrid angiographic suite with intraoperative computed tomography (iCT) to evaluate accuracy of pedicle screw placement in spinal fusion. This retrospective review examines how well iCT detected extrapedicular screw violation, to then allow repositioning and potentially avoid revision surgery. METHODS: A total of 36 consecutive patients underwent pedicle screw placement in posterior cervical, thoracic, and lumbosacral spinal fusions...
March 10, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28242408/a-rare-entity-traumatic-thoracic-aortic-injury-in-a-patient-with-aberrant-right-subclavian-artery
#7
Hiten Mohanbhai Patel, Shubhabrata Banerjee, Shahzad Bulsara, Tapish Sahu, Virender K Sheorain, Tarun Grover, Rajiv Parakh
BACKGROUND: Aberrant right subclavian artery is an uncommon entity incidence ranging from 0.5 to 2.5%. Management of thoracic aortic injury in the presence of such anomalies can be a challenge. We present here a case of traumatic aortic injury, which was incidentally found to have an asymptomatic aberrant right subclavian artery. The patient was managed by an endovascular repair of thoracic aortic injury with an endograft and a right carotid to subclavian artery bypass as a hybrid procedure...
May 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28221755/multilevel-ultrafast-flexible-nanoscale-nonvolatile-hybrid-graphene-oxide-titanium-oxide-memories
#8
V Karthik Nagareddy, Matthew D Barnes, Federico Zipoli, Khue T Lai, Arseny M Alexeev, Monica Felicia Craciun, C David Wright
Graphene oxide (GO) resistive memories offer the promise of low-cost environmentally sustainable fabrication, high mechanical flexibility and high optical transparency, making them ideally suited to future flexible and transparent electronics applications. However, the dimensional and temporal scalability of GO memories, i.e., how small they can be made and how fast they can be switched, is an area that has received scant attention. Moreover, a plethora of GO resistive switching characteristics and mechanisms has been reported in the literature, sometimes leading to a confusing and conflicting picture...
March 28, 2017: ACS Nano
https://www.readbyqxmd.com/read/28066676/image-guided-localization-of-small-lung-nodules-in-video-assisted-thoracic-surgery
#9
REVIEW
Ze-Rui Zhao, Rainbow W H Lau, Peter S Y Yu, Randolph H L Wong, Calvin S H Ng
The advancement of imaging technology has recently facilitated single port minimally-invasive thoracic surgery techniques. Cone-beam computed tomography (CBCT) shows promising results in visualizing the target lesion and its surrounding critical anatomy, with an error of less than 2 mm. The integration of CBCT with the operating room (OR) to form the hybrid OR, provides unparalleled real-time imaging of the patient, which can be used with electromagnetic navigation bronchoscopy to confirm successful navigation and increase procedural accuracy particularly for small peripheral pulmonary targets...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28054168/minimally-invasive-surgery-for-complicated-diverticulitis
#10
Najjia N Mahmoud, Elijah W Riddle
Recent guidelines recommend an individualized approach to recurrent uncomplicated diverticulitis, reflecting research showing that non-operative treatment is safe. Thus, the majority of operations for diverticulitis in the future may be for complicated indications. A laparoscopic approach may be used for both acute and chronic complicated diverticulitis in appropriate patients, as described in the American and European guidelines. However, a safe approach to minimally invasive surgery requires recognition when conditions deteriorate or are not suited to laparoscopy as well as knowledge of a variety of technical maneuvers that elucidate difficult anatomy and facilitate resection...
April 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27958358/ultrathin-terahertz-quarter-wave-plate-based-on-split-ring-resonator-and-wire-grating-hybrid-metasurface
#11
Muhammad Tayyab Nouman, Ji Hyun Hwang, Jae-Hyung Jang
Planar metasurface based quarter-wave plates offer various advantages over conventional waveplates in terms of compactness, flexibility and simple fabrication; however they offer very narrow bandwidth of operation. Here, we demonstrate a planar terahertz (THz) metasurface capable of linear to circular polarization conversion and vice versa in a wide frequency range. The proposed metasurface is based on horizontally connected split ring resonators and is realized on an ultrathin (0.05λ) zeonor substrate. The fabricated quarter waveplate realizes linear to circular polarization conversion in two broad frequency bands comprising 0...
December 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27779136/petpvc-a-toolbox-for-performing-partial-volume-correction-techniques-in-positron-emission-tomography
#12
Benjamin A Thomas, Vesna Cuplov, Alexandre Bousse, Adriana Mendes, Kris Thielemans, Brian F Hutton, Kjell Erlandsson
Positron emission tomography (PET) images are degraded by a phenomenon known as the partial volume effect (PVE). Approaches have been developed to reduce PVEs, typically through the utilisation of structural information provided by other imaging modalities such as MRI or CT. These methods, known as partial volume correction (PVC) techniques, reduce PVEs by compensating for the effects of the scanner resolution, thereby improving the quantitative accuracy. The PETPVC toolbox described in this paper comprises a suite of methods, both classic and more recent approaches, for the purposes of applying PVC to PET data...
November 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27725826/hybrid-artificial-root-foraging-optimizer-based-multilevel-threshold-for-image-segmentation
#13
Yang Liu, Junfei Liu, Liwei Tian, Lianbo Ma
This paper proposes a new plant-inspired optimization algorithm for multilevel threshold image segmentation, namely, hybrid artificial root foraging optimizer (HARFO), which essentially mimics the iterative root foraging behaviors. In this algorithm the new growth operators of branching, regrowing, and shrinkage are initially designed to optimize continuous space search by combining root-to-root communication and coevolution mechanism. With the auxin-regulated scheme, various root growth operators are guided systematically...
2016: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/27602911/angiographic-embolization-for-hemorrhage-following-pelvic-fracture-is-it-time-for-a-paradigm-shift
#14
Ronald Brian Tesoriero, Brandon R Bruns, Mayur Narayan, Joseph Dubose, Sundeep S Guliani, Megan L Brenner, Sharon Boswell, Deborah M Stein, Thomas M Scalea
INTRODUCTION: Major pelvic disruption with hemorrhage has a high rate of lethality. Angiographic embolization remains the mainstay of treatment. Delays to angiography have been shown to worsen outcomes in part because time spent awaiting mobilization of resources needed to perform angiography allows ongoing hemorrhage. Alternative techniques like pelvic preperitoneal packing and aortic balloon occlusion now exist. We hypothesized that time to angiographic embolization at our Level 1 trauma center would be longer than 90 minutes...
January 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27505382/degradation-nonuniformity-in-the-solar-diffuser-bidirectional-reflectance-distribution-function
#15
Junqiang Sun, Mike Chu, Menghua Wang
The assumption of angular dependence stability of the solar diffuser (SD) throughout degradation is critical to the on-orbit calibration of the reflective solar bands (RSBs) in many satellite sensors. Recent evidence has pointed to the contrary, and in this work, we present a thorough investigative effort into the angular dependence of the SD degradation for the Visible Infrared Imaging Radiometer Suite (VIIRS) onboard the Suomi National Polar-orbiting Partnership (SNPP) satellite and for the twin Moderate-resolution Imaging Spectroradiometer (MODIS) onboard Terra and Aqua spacecrafts...
August 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27495341/superselective-intra-arterial-hepatic-injection-of-indocyanine-green-icg-for-fluorescence-image-guided-segmental-positive-staining-experimental-proof-of-the-concept
#16
Michele Diana, Yu-Yin Liu, Raoul Pop, Seong-Ho Kong, Andras Legnèr, Remy Beaujeux, Patrick Pessaux, Luc Soler, Didier Mutter, Bernard Dallemagne, Jacques Marescaux
BACKGROUND: Intraoperative liver segmentation can be obtained by means of percutaneous intra-portal injection of a fluorophore and illumination with a near-infrared light source. However, the percutaneous approach is challenging in the minimally invasive setting. We aimed to evaluate the feasibility of fluorescence liver segmentation by superselective intra-hepatic arterial injection of indocyanine green (ICG). MATERIALS AND METHODS: Eight pigs (mean weight: 26...
March 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/27494822/endoscope-assisted-transsphenoidal-puncture-of-the-cavernous-sinus-for-embolization-of-carotid-cavernous-fistula-in-a-neurosurgical-hybrid-operating-suite
#17
Chien-Lun Tang, Chih-Hsiang Liao, Wen-Hsien Chen, Shih-Chieh Shen, Chung-Hsin Lee, Hsu-Tung Lee, Yuang-Seng Tsuei
Endovascular embolization is the treatment of choice for carotid-cavernous fistulas (CCFs), but failure to catheterize the cavernous sinus may occur as a result of vessel tortuosity, hypoplasia, or stenosis. In addition to conventional transvenous or transarterial routes, alternative approaches should be considered. The authors present a case in which a straightforward route to the CCF was accessed via transsphenoidal puncture of the cavernous sinus in a neurosurgical hybrid operating suite. This 82-year-old man presented with severe chemosis and proptosis of the right eye...
August 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27486345/computed-tomography-and-magnetic-resonance-imaging-contrast-media-injectors-technical-feature-review-what-is-really-needed
#18
REVIEW
Michael Friebe
There has been little technical innovation over the last few years for contrast media (CM) injectors that are used for diagnostic imaging (computed tomography [CT], magnetic resonance imaging [MRI], and hybrid imaging systems, such as positron emission tomography-CT or magnetic resonance-positron emission tomography) examinations. The medical need of CM for the enhancement of diagnostic images has been around for a long time, but the application of the CM into the blood stream comes with potential medical complications for the patient and requires a lot of operator experience and training...
2016: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/27464941/a-novel-and-multidisciplinary-strategy-for-cesarean-delivery-with-placenta-percreta-intraoperative-embolization-in-a-hybrid-suite
#19
Yasutaka Konishi, Satoshi Yamamoto, Kei Sugiki, Hidetoshi Sakamoto, Shigehito Sawamura
Cesarean deliveries in patients with placenta accreta often are accompanied by life-threatening bleeding and sometimes death. A novel, multidisciplinary approach that uses uterine embolization after cesarean delivery recently has been advocated; however, embolization in the radiology department requires transfer of postoperative patients, which could increase maternal mortality and morbidity. In a case of severe placenta accreta, we planned a stepwise treatment, including cesarean delivery without separation of the placenta followed by intraoperative uterine arterial embolization in a hybrid operating room, followed by hysterectomy a few weeks after cesarean delivery...
September 15, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27301836/managing-disruptions-to-patient-flow-capacity-rapid-cycle-improvement-in-a-pediatric-cardiac-procedure-complex
#20
Debbie McKetta, T Eugene Day, Virginia Jones, Alexis Perri, Susan C Nicolson
BACKGROUND: Managing service disruptions is a challenge in every health care environment. Discrete event simulation (DES)--a computer modeling tool used to build in silico (that is, in a digital computer) testbeds for potential changes in complex systems--has been deployed in health care for research and quality improvement (QI), specifically in surgical suite management. A strategy for managing a 6-week planned service disruption needed to be enacted 12 weeks after the announcement, in late October 2014, of the closure of the Hybrid Suite (operating room/catheterization laboratory) for renovation, at The Children's Hospital of Philadelphia's Cardiac Center's Cardiac Operative and Imaging Complex (COIC)...
July 2016: Joint Commission Journal on Quality and Patient Safety
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