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https://www.readbyqxmd.com/read/28427706/neuromyelitis-optica-spectrum-disorder-related-tonic-spasms-responsive-to-lacosamide
#1
A Baheerathan, W J Brownlee, F Rugg-Gunn, D T Chard, S A Trip
Paroxysmal tonic spasms [PTS] are common in patients with neuromyelitis optica spectrum disorder (NMOSD).1 2 In patients with demyelinating disease, PTS can significantly reduce the quality of life, limit activities of daily living and the rehabilitative process following an acute relapse 3. As in patients with multiple sclerosis (MS), paroxysmal tonic spasms in NMOSD usually respond well to treatment with carbamazepine.2 However, the optimal treatment in patients where carbamazepine is contraindicated or poorly tolerated is unclear...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28427332/interrater-and-test-retest-reliability-and-validity-of-the-norwegian-version-of-the-bestest-and-mini-bestest-in-people-with-increased-risk-of-falling
#2
Charlotta Hamre, Pernille Botolfsen, Gro Gujord Tangen, Jorunn L Helbostad
BACKGROUND: The Balance Evaluation Systems Test (BESTest) was developed to assess underlying systems for balance control in order to be able to individually tailor rehabilitation interventions to people with balance disorders. A short form, the Mini-BESTest, was developed as a screening test. The study aimed to assess interrater and test-retest reliability of the Norwegian version of the BESTest and the Mini-BESTest in community-dwelling people with increased risk of falling and to assess concurrent validity with the Fall Efficacy Scale-International (FES-I), and it was an observational study with a cross-sectional design...
April 20, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28394185/physical-activity-and-exercise-priorities-in-community-dwelling-people-with-multiple-sclerosis-a-delphi-study
#3
Andrea Stennett, Lorraine De Souza, Meriel Norris
AIMS: Exercise and physical activity have been found to be beneficial in managing disabilities caused by multiple sclerosis. Despite the known benefits, many people with multiple sclerosis are inactive. This study aimed to identify the prioritised exercise and physical activity practices of people with multiple sclerosis living in the community and the reasons why they are engaged in these activities. METHODS: A four Round Delphi questionnaire scoped and determined consensus of priorities for the top 10 exercise and physical activities and the reasons why people with multiple sclerosis (n = 101) are engaged in these activities...
April 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28387447/withdrawn-interventions-for-fatigue-and-weight-loss-in-adults-with-advanced-progressive-illness
#4
REVIEW
Cathy Payne, Philip J Wiffen, Suzanne Martin
BACKGROUND: Fatigue and unintentional weight loss are two of the commonest symptoms experienced by people with advanced progressive illness. Appropriate interventions may bring considerable improvements in function and quality of life to seriously ill people and their families, reducing physical, psychological and spiritual distress. OBJECTIVES: To conduct an overview of the evidence available on the efficacy of interventions used in the management of fatigue and/or unintentional weight loss in adults with advanced progressive illness by reviewing the evidence contained within Cochrane reviews...
April 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28381930/interference-effect-of-prior-explicit-information-on-motor-sequence-learning-in-relapsing-remitting-multiple-sclerosis-patients
#5
Nahid Zahiri, Iraj Abollahi, Seyed Massood Nabavi, Fatemeh Ehsani, Amir Masoud Arab, Ina Shaw, Ardalan Shariat, Brandon S Shaw, Maryam Dastoorpoor, Mahmoud Danaee, Bahram Sangelaji
BACKGROUND: Multiple sclerosis (MS) is the most widespread disabling neurological condition in young adults around the world. The purpose of this study was to investigate the impact of explicit information (EI) on motor-sequence learning in MS patients. METHODS: Thirty patients with relapsing-remitting MS (RRMS), age: 29.5 (SD = 5.6) years and 30 healthy gender-, age-, and education-matched control group participants, age: 28.8 (SD = 6.0) years, were recruited for this study...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28376639/the-effect-of-symptom-controlling-medication-on-gait-outcomes-in-people-with-multiple-sclerosis-a-systematic-review
#6
Kate Behm, Prue Morgan
PURPOSE: To synthesise and critically appraise randomised controlled trials examining the effect of symptom-controlling medication on gait outcomes in people with multiple sclerosis (MS). METHOD: The literature search examined five databases (Medline, Embase, AMED, Cochrane (CENTRAL), and CINAHL until the end of November 2016. Eligible studies included medication to address symptoms associated with MS and an objective gait outcome measure. Two reviewers independently extracted data and assessed study quality using structured data extraction forms and the PEDro scale...
April 4, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28359178/the-impact-of-multiple-sclerosis-on-the-identity-of-mothers-in-italy
#7
Catherine Louise Willson, Josie Tetley, Cathy Lloyd, Michele Messmer Uccelli, Sara MacKian
PURPOSE: This paper reports on one of the themes that emerged from the analysis of the study, regarding the perceived influence of multiple sclerosis (MS) on the identity of mothers in the socio-cultural context of Italy. METHOD: In-depth interviews were conducted with 16 women at various stages of MS, with follow up interviews with seven of the women. Phenomenology guided the methodology and the analysis was conducted using interpretative phenomenological analysis...
March 30, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28356727/effects-of-dual-tasks-and-dual-task-training-on-postural-stability-a-systematic-review-and-meta-analysis
#8
REVIEW
Shashank Ghai, Ishan Ghai, Alfred O Effenberg
The use of dual-task training paradigm to enhance postural stability in patients with balance impairments is an emerging area of interest. The differential effects of dual tasks and dual-task training on postural stability still remain unclear. A systematic review and meta-analysis were conducted to analyze the effects of dual task and training application on static and dynamic postural stability among various population groups. Systematic identification of published literature was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, from inception until June 2016, on the online databases Scopus, PEDro, MEDLINE, EMBASE, and SportDiscus...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28355925/exploring-change-in-a-group-based-psychological-intervention-for-multiple-sclerosis-patients
#9
Martina Borghi, Silvia Bonino, Federica Graziano, Emanuela Calandri
PURPOSE: The study is focused on a group-based cognitive behavioral intervention aimed at promoting the quality of life and psychological well-being of multiple sclerosis patients. The study investigates how the group intervention promoted change among participants and fostered their adjustment to the illness. MATERIALS AND METHODS: The intervention involved six groups of patients (a total of 41 patients) and included four consecutive sessions and a 6-month follow-up...
March 30, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28338498/challenge-of-progressive-multiple-sclerosis-therapy
#10
Alan J Thompson
PURPOSE OF REVIEW: Understanding the mechanisms underlying progression in multiple sclerosis (MS) and identifying appropriate therapeutic targets is a key challenge facing the MS community. This challenge has been championed internationally by organizations such as the Progressive MS Alliance, which has raised the profile of progressive MS and identified the key obstacles to treatment. This review will outline the considerable progress against these challenges. RECENT FINDINGS: New insights into mechanisms underlying progression have opened up potential therapeutic opportunities...
March 23, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28336344/participation-restriction-in-people-with-multiple-sclerosis-prevalence-and-correlations-with-cognitive-walking-balance-and-upper-limb-impairments
#11
Davide Cattaneo, Ilse Lamers, Rita Bertoni, Peter Feys, Johanna Jonsdottir
OBJECTIVE: To calculate percentage of participation restrictions according to disability level in Multiple Sclerosis (MS) and to assess relationship between participation restriction, and cognitive, gait, balance and upper limb deficits. DESIGN: Cross sectional study SETTING: Rehabilitation unit PARTICIPANTS: 105 people with MS and 20 healthy subjects (HS) were screened in Belgium and Italy. INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: The Community integration questionnaire was used to assess participation in Home, Social and Productive Activities...
March 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28325094/validity-and-reliability-of-the-multidimensional-assessment-of-fatigue-scale-in-iranian-patients-with-relapsing-remitting-subtype-of-multiple-sclerosis
#12
Shabnam Behrangrad, Amin Kordi Yoosefinejad
PURPOSE: The purpose of this study is to investigate the validity and reliability of the Persian version of the Multidimensional Assessment of Fatigue Scale (MAFS) in an Iranian population with multiple sclerosis. METHOD: A self-reported survey on fatigue including the MAFS, Fatigue Impact Scale and demographic measures was completed by 130 patients with multiple sclerosis and 60 healthy persons sampled with a convenience method. Test-retest reliability and validity were evaluated 3 days apart...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28322588/a-questionnaire-study-to-explore-the-views-of-people-with-multiple-sclerosis-of-using-smartphone-technology-for-health-care-purposes
#13
Nicola Griffin, Maria Kehoe
PURPOSE: Delivering interventions over the lifetime of people with chronic conditions is an international healthcare challenge. The benefits of technology in healthcare have been demonstrated in many health conditions. This study aims to seek the views of People with multiple sclerosis (MS) of the feasibility and perceived acceptability of smartphone use for healthcare purposes. METHODS: Using SurveyMonkey™, respondents answered 21 items about their smartphone use and acceptance of smartphones in healthcare...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28302081/patient-reported-questionnaires-in-ms-rehabilitation-responsiveness-and-minimal-important-difference-of-the-multiple-sclerosis-questionnaire-for-physiotherapists-msqpt
#14
Nico Arie van der Maas
BACKGROUND: The Multiple Sclerosis Questionnaire for Physical Therapists (MSQPT) is a patient-rated outcome questionnaire for evaluating the rehabilitation of persons with multiple sclerosis (MS). Responsiveness was evaluated, and minimal important difference (MID) estimates were calculated to provide thresholds for clinical change for four items, three sections and the total score of the MSQPT. METHODS: This multicentre study used a combined distribution- and anchor-based approach with multiple anchors and multiple rating of change questions...
March 16, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28293978/piloting-an-email-based-resource-package-for-job-seekers-with-multiple-sclerosis
#15
Diana Dorstyn, Rachel Roberts, Gregory Murphy, Ian Kneebone, Christine Migliorini, Ashley Craig, Claire Hutchinson, Deborah Field
PURPOSE: Media-based rehabilitation provides a powerful opportunity to examine vocational behaviors in the disability sector. However, this research is preliminary at best. This paper reports pilot data. METHOD: Eighteen adults with multiple sclerosis (MS) accessed an email-delivered, resource-based package, Work and MS. Pre- and post-access vocational self-efficacy and identity (Job-Procurement Self Efficacy Scale, My Vocational Situation Scale- primary outcomes), life orientation and depressed mood (Life Orientation Test - revised and Patient Health Questionnaire-9 - secondary outcomes) were assessed...
May 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28291956/physical-activity-motivation-and-benefits-in-people-with-multiple-sclerosis
#16
Kimberly S Fasczewski, Diane L Gill, Sara M Rothberger
PURPOSE: Multiple sclerosis is a degenerative neurological disease that affects 2.1 million people worldwide. There is no cure, but an expanding body of research supports the positive impact of physical activity and suggests physical activity has benefits for the individual's psychological and physical well-being. MATERIAL AND METHODS: Using Self-Determination Theory as a framework, mixed methods with a focus on qualitative interviews were used to explore physical activity motivation and benefits with a sample of highly active people with multiple sclerosis (n = 15)...
March 14, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28289599/quantitative-measures-of-walking-and-strength-provide-insight-into-brain-corticospinal-tract-pathology-in-multiple-sclerosis
#17
Nora E Fritz, Jennifer Keller, Peter A Calabresi, Kathleen M Zackowski
At least 85% of individuals with multiple sclerosis report walking dysfunction as their primary complaint. Walking and strength measures are common clinical measures to mark increasing disability or improvement with rehabilitation. Previous studies have shown an association between strength or walking ability and spinal cord MRI measures, and strength measures with brainstem corticospinal tract magnetization transfer ratio. However, the relationship between walking performance and brain corticospinal tract magnetization transfer imaging measures and the contribution of clinical measurements of walking and strength to the underlying integrity of the corticospinal tract has not been explored in multiple sclerosis...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28285547/objective-physical-activity-measurement-in-people-with-multiple-sclerosis-a-review-of-the-literature
#18
Blathin Casey, Susan Coote, Alan Donnelly
PURPOSE: The purpose of this study is to identify the objective physical activity (PA) measurement tools and outputs that are used within Multiple Sclerosis (MS) literature. METHODS: A systematic search strategy on eight databases (2000-2016) using keywords associated with MS and PA. RESULTS: This review includes 32 papers. Uni-axial accelerometers were the most popular objective PA tool in this review (68%). Pedometers (14%) and multi-sensor systems (3%) were the second and third most common...
March 13, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28273775/new-insights-into-the-burden-and-costs-of-multiple-sclerosis-in-europe
#19
Gisela Kobelt, Alan Thompson, Jenny Berg, Mia Gannedahl, Jennifer Eriksson
BACKGROUND: The current focus in multiple sclerosis (MS) is on early diagnosis and drug intervention, with a view to modifying disease progression. Consequently, healthcare costs have shifted from inpatient care and rehabilitation to outpatient care. OBJECTIVES: This European burden of illness study provides data that can be combined with other evidence to assess whether management approaches provide value to society. METHODS: A cross-sectional study was conducted in 16 countries...
February 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28263255/self-efficacy-and-walking-performance-in-persons-with-multiple-sclerosis
#20
Robert W Motl, Julia M Balto, Ipek Ensari, Elizabeth A Hubbard
BACKGROUND AND PURPOSE: Impairment of walking function is a prevalent and burdensome feature of multiple sclerosis (MS), and represents a primary focus of rehabilitation research and clinical care. Research examining self-efficacy as a correlate of walking performance in MS is lacking; self-efficacy represents a theory-based, modifiable target of rehabilitation approaches for improving walking outcomes. This cross-sectional study examined the association between self-efficacy and walking performance in persons living with MS...
April 2017: Journal of Neurologic Physical Therapy: JNPT
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