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multiple sclerosis rehabilitation

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https://www.readbyqxmd.com/read/28338498/challenge-of-progressive-multiple-sclerosis-therapy
#1
Alan J Thompson
PURPOSE OF REVIEW: Understanding the mechanisms underlying progression in multiple sclerosis (MS) and identifying appropriate therapeutic targets is a key challenge facing the MS community. This challenge has been championed internationally by organizations such as the Progressive MS Alliance, which has raised the profile of progressive MS and identified the key obstacles to treatment. This review will outline the considerable progress against these challenges. RECENT FINDINGS: New insights into mechanisms underlying progression have opened up potential therapeutic opportunities...
March 23, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28336344/participation-restriction-in-people-with-multiple-sclerosis-prevalence-and-correlations-with-cognitive-walking-balance-and-upper-limb-impairments
#2
Davide Cattaneo, Ilse Lamers, Rita Bertoni, Peter Feys, Johanna Jonsdottir
OBJECTIVE: To calculate percentage of participation restrictions according to disability level in Multiple Sclerosis (MS) and to assess relationship between participation restriction, and cognitive, gait, balance and upper limb deficits. DESIGN: Cross sectional study SETTING: Rehabilitation unit PARTICIPANTS: 105 people with MS and 20 healthy subjects (HS) were screened in Belgium and Italy. INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: The Community integration questionnaire was used to assess participation in Home, Social and Productive Activities...
March 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28325094/validity-and-reliability-of-the-multidimensional-assessment-of-fatigue-scale-in-iranian-patients-with-relapsing-remitting-subtype-of-multiple-sclerosis
#3
Shabnam Behrangrad, Amin Kordi Yoosefinejad
PURPOSE: The purpose of this study is to investigate the validity and reliability of the Persian version of the Multidimensional Assessment of Fatigue Scale (MAFS) in an Iranian population with multiple sclerosis. METHOD: A self-reported survey on fatigue including the MAFS, Fatigue Impact Scale and demographic measures was completed by 130 patients with multiple sclerosis and 60 healthy persons sampled with a convenience method. Test-retest reliability and validity were evaluated 3 days apart...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28322588/a-questionnaire-study-to-explore-the-views-of-people-with-multiple-sclerosis-of-using-smartphone-technology-for-health-care-purposes
#4
Nicola Griffin, Maria Kehoe
PURPOSE: Delivering interventions over the lifetime of people with chronic conditions is an international healthcare challenge. The benefits of technology in healthcare have been demonstrated in many health conditions. This study aims to seek the views of People with multiple sclerosis (MS) of the feasibility and perceived acceptability of smartphone use for healthcare purposes. METHODS: Using SurveyMonkey™, respondents answered 21 items about their smartphone use and acceptance of smartphones in healthcare...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28302081/patient-reported-questionnaires-in-ms-rehabilitation-responsiveness-and-minimal-important-difference-of-the-multiple-sclerosis-questionnaire-for-physiotherapists-msqpt
#5
Nico Arie van der Maas
BACKGROUND: The Multiple Sclerosis Questionnaire for Physical Therapists (MSQPT) is a patient-rated outcome questionnaire for evaluating the rehabilitation of persons with multiple sclerosis (MS). Responsiveness was evaluated, and minimal important difference (MID) estimates were calculated to provide thresholds for clinical change for four items, three sections and the total score of the MSQPT. METHODS: This multicentre study used a combined distribution- and anchor-based approach with multiple anchors and multiple rating of change questions...
March 16, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28293978/piloting-an-email-based-resource-package-for-job-seekers-with-multiple-sclerosis
#6
Diana Dorstyn, Rachel Roberts, Gregory Murphy, Ian Kneebone, Christine Migliorini, Ashley Craig, Claire Hutchinson, Deborah Field
PURPOSE: Media-based rehabilitation provides a powerful opportunity to examine vocational behaviors in the disability sector. However, this research is preliminary at best. This paper reports pilot data. METHOD: Eighteen adults with multiple sclerosis (MS) accessed an email-delivered, resource-based package, Work and MS. Pre- and post-access vocational self-efficacy and identity (Job-Procurement Self Efficacy Scale, My Vocational Situation Scale- primary outcomes), life orientation and depressed mood (Life Orientation Test - revised and Patient Health Questionnaire-9 - secondary outcomes) were assessed...
May 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28291956/physical-activity-motivation-and-benefits-in-people-with-multiple-sclerosis
#7
Kimberly S Fasczewski, Diane L Gill, Sara M Rothberger
PURPOSE: Multiple sclerosis is a degenerative neurological disease that affects 2.1 million people worldwide. There is no cure, but an expanding body of research supports the positive impact of physical activity and suggests physical activity has benefits for the individual's psychological and physical well-being. MATERIAL AND METHODS: Using Self-Determination Theory as a framework, mixed methods with a focus on qualitative interviews were used to explore physical activity motivation and benefits with a sample of highly active people with multiple sclerosis (n = 15)...
March 14, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28289599/quantitative-measures-of-walking-and-strength-provide-insight-into-brain-corticospinal-tract-pathology-in-multiple-sclerosis
#8
Nora E Fritz, Jennifer Keller, Peter A Calabresi, Kathleen M Zackowski
At least 85% of individuals with multiple sclerosis report walking dysfunction as their primary complaint. Walking and strength measures are common clinical measures to mark increasing disability or improvement with rehabilitation. Previous studies have shown an association between strength or walking ability and spinal cord MRI measures, and strength measures with brainstem corticospinal tract magnetization transfer ratio. However, the relationship between walking performance and brain corticospinal tract magnetization transfer imaging measures and the contribution of clinical measurements of walking and strength to the underlying integrity of the corticospinal tract has not been explored in multiple sclerosis...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28285547/objective-physical-activity-measurement-in-people-with-multiple-sclerosis-a-review-of-the-literature
#9
Blathin Casey, Susan Coote, Alan Donnelly
PURPOSE: The purpose of this study is to identify the objective physical activity (PA) measurement tools and outputs that are used within Multiple Sclerosis (MS) literature. METHODS: A systematic search strategy on eight databases (2000-2016) using keywords associated with MS and PA. RESULTS: This review includes 32 papers. Uni-axial accelerometers were the most popular objective PA tool in this review (68%). Pedometers (14%) and multi-sensor systems (3%) were the second and third most common...
March 13, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28273775/new-insights-into-the-burden-and-costs-of-multiple-sclerosis-in-europe
#10
Gisela Kobelt, Alan Thompson, Jenny Berg, Mia Gannedahl, Jennifer Eriksson
BACKGROUND: The current focus in multiple sclerosis (MS) is on early diagnosis and drug intervention, with a view to modifying disease progression. Consequently, healthcare costs have shifted from inpatient care and rehabilitation to outpatient care. OBJECTIVES: This European burden of illness study provides data that can be combined with other evidence to assess whether management approaches provide value to society. METHODS: A cross-sectional study was conducted in 16 countries...
February 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28263255/self-efficacy-and-walking-performance-in-persons-with-multiple-sclerosis
#11
Robert W Motl, Julia M Balto, Ipek Ensari, Elizabeth A Hubbard
BACKGROUND AND PURPOSE: Impairment of walking function is a prevalent and burdensome feature of multiple sclerosis (MS), and represents a primary focus of rehabilitation research and clinical care. Research examining self-efficacy as a correlate of walking performance in MS is lacking; self-efficacy represents a theory-based, modifiable target of rehabilitation approaches for improving walking outcomes. This cross-sectional study examined the association between self-efficacy and walking performance in persons living with MS...
April 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28255373/effect-of-rhythmic-auditory-stimulation-on-gait-kinematic-parameters-of-patients-with-multiple-sclerosis
#12
REVIEW
M Shahraki, M Sohrabi, H R Taheri Torbati, K Nikkhah, M NaeimiKia
Purpose: This study aimed to examine the effect of rhythmic auditory stimulation on gait kinematic parameters of patients with multiple sclerosis. Subjects and Methods: In this study, 18 subjects, comprising 4 males and 14 females with Multiple Sclerosis with expanded disability status scale of 3 to 6 were chosen. Subjects were selected by available and targeted sampling and were randomly divided into two experimental (n = 9) and control (n = 9) groups. Exercises were gait with rhythmic auditory stimulation by a metronome device, in addition to gait without stimulation for the experimental and control groups, respectively...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28243186/a-framework-of-care-in-multiple-sclerosis-part-2-symptomatic-care-and-beyond
#13
Scott D Newsome, Philip J Aliotta, Jacquelyn Bainbridge, Susan E Bennett, Gary Cutter, Kaylan Fenton, Fred Lublin, Dorothy Northrop, David Rintell, Bryan D Walker, Megan Weigel, Kathleen Zackowski, David E Jones
The Consortium of Multiple Sclerosis Centers (CMSC) convened a Framework Taskforce composed of a multidisciplinary group of clinicians and researchers to examine and evaluate the current models of care in multiple sclerosis (MS). The methodology of this project included analysis of a needs assessment survey and an extensive literature review. The outcome of this work is a two-part continuing education series of articles. Part 1, published previously, covered the updated disease phenotypes of MS along with recommendations for the use of disease-modifying therapies...
January 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28241776/the-effectiveness-of-robot-assisted-gait-training-versus-conventional-therapy-on-mobility-in-severely-disabled-progressive-multiple-sclerosis-patients-ragtime-study-protocol-for-a-randomized-controlled-trial
#14
Sofia Straudi, Fabio Manfredini, Nicola Lamberti, Paolo Zamboni, Francesco Bernardi, Giovanna Marchetti, Paolo Pinton, Massimo Bonora, Paola Secchiero, Veronica Tisato, Stefano Volpato, Nino Basaglia
BACKGROUND: Gait and mobility impairments affect the quality of life (QoL) of patients with progressive multiple sclerosis (MS). Robot-assisted gait training (RAGT) is an effective rehabilitative treatment but evidence of its superiority compared to other options is lacking. Furthermore, the response to rehabilitation is multidimensional, person-specific and possibly involves functional reorganization processes. The aims of this study are: (1) to test the effectiveness on gait speed, mobility, balance, fatigue and QoL of RAGT compared to conventional therapy (CT) in progressive MS and (2) to explore changes of clinical and circulating biomarkers of neural plasticity...
February 27, 2017: Trials
https://www.readbyqxmd.com/read/28223806/efficacy-of-a-short-cognitive-training-program-in-patients-with-multiple-sclerosis
#15
María Yaiza Pérez-Martín, Montserrat González-Platas, Pablo Eguía-Del Río, Cristina Croissier-Elías, Alejandro Jiménez Sosa
BACKGROUND: Cognitive impairment is a common feature in multiple sclerosis (MS) and may have a substantial impact on quality of life. Evidence about the effectiveness of neuropsychological rehabilitation is still limited, but current data suggest that computer-assisted cognitive training improves cognitive performance. OBJECTIVE: The objective of this study was to evaluate the efficacy of combined computer-assisted training supported by home-based neuropsychological training to improve attention, processing speed, memory and executive functions during 3 consecutive months...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28218343/immediate-affective-responses-of-gait-training-in-neurological-rehabilitation-a-randomized-crossover-trial
#16
Martin Niedermeier, Larissa Ledochowski, Andreas Mayr, Leopold Saltuari, Martin Kopp
OBJECTIVE: To examine the immediate effects of physical therapy and robotic-assisted gait training on affective responses of gait training in neurological rehabilitation. DESIGN: Randomized crossover trial with blinded observers. PATIENTS: Sixteen patients with neurological disorders (stroke, traumatic brain injury, spinal cord injury, multiple sclerosis). METHODS: All patients underwent 2 single treatment sessions: physical therapy and robotic-assisted gait training...
February 16, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28215060/efficacy-of-aquatic-therapy-for-multiple-sclerosis-a-systematic-review
#17
Iluminada Corvillo, Enrique Varela, Francisco Armijo, Antonio Alvarez-Badillo, Onica Armijo, Francisco Maraver
BACKGROUND: Multiple sclerosis (MS) is a chronic, inflammatory, progressive, disabling autoimmune disease affecting the central nervous system. Symptoms and signs of MS vary widely and patients may lose their ability to walk. To date the benefits of aquatic therapy often used for rehabilitation in MS patients have not been reviewed. OBJECTIVE: To systematically review the current state of aquatic treatment for persons with MS (hydrotherapy, aquatic therapy, aquatic exercises, spa therapy) and to evaluate the scientific evidence supporting the benefits of this therapeutic option...
February 17, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28206828/validity-of-the-timed-25-foot-walk-as-an-ambulatory-performance-outcome-measure-for-multiple-sclerosis
#18
Robert W Motl, Jeffrey A Cohen, Ralph Benedict, Glenn Phillips, Nicholas LaRocca, Lynn D Hudson, Richard Rudick
The Multiple Sclerosis Outcome Assessments Consortium (MSOAC) includes representatives from advocacy organizations, Food and Drug Administration (FDA), European Medicines Agency (EMA), National Institute of Neurological Disorders and Stroke (NINDS), academic institutions, and industry partners along with persons living with multiple sclerosis (MS). One of the MSOAC goals is acceptance and qualification by regulators of performance outcomes that are highly reliable and valid, practical, cost-effective, and meaningful in MS...
February 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28130080/fatigability-in-patients-with-multiple-sclerosis-during-maximal-concentric-contractions
#19
Sophie Hameau, Djamel Bensmail, Nicolas Roche, Raphaël Zory
OBJECTIVE: To compare quadriceps fatigability during maximal concentric contractions in persons with multiple sclerosis (MS) and healthy subjects. DESIGN: Observational study. SETTING: Hospital rehabilitation department. PARTICIPANTS: Persons with MS (n=38) and healthy subjects (n=14) were included (N=52). Torque of the knee flexor and extensor muscles and fatigability of the knee extensor muscles were evaluated using an isokinetic device...
January 25, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28125300/the-impact-of-robot-mediated-adaptive-i-travle-training-on-impaired-upper-limb-function-in-chronic-stroke-and-multiple-sclerosis
#20
Anneleen Maris, Karin Coninx, Henk Seelen, Veronik Truyens, Tom De Weyer, Richard Geers, Mieke Lemmens, Jolijn Coolen, Sandra Stupar, Ilse Lamers, Peter Feys
PURPOSE: The current study aimed to investigate proof-of-concept efficacy of an individualized, robot-mediated training regime for people with MS (pwMS) and stroke patients. METHOD: Thirteen pwMS and 14 chronic stroke patients performed 36 (stroke) or 40 (pwMS) training sessions with the I-TRAVLE system. Evaluation of upper limb function was performed at baseline, after training and at 3 months follow-up. Clinical outcome measures consisted of active range of motion (ROM), Motricity Index, Jamar handgrip strength, perceived fatigue and strength, Wolf Motor Function Test (WFMT) and ABILHAND...
January 26, 2017: Disability and Rehabilitation. Assistive Technology
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