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multiple sclerosis rehabilitation

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https://www.readbyqxmd.com/read/29145345/the-role-of-sativex-in-robotic-rehabilitation-in-individuals-with-multiple-sclerosis-rationale-study-design-and-methodology
#1
Margherita Russo, Vincenzo Dattola, Anna Lisa Logiudice, Rosella Ciurleo, Edoardo Sessa, Rosaria De Luca, Placido Bramanti, Alessia Bramanti, Antonino Naro, Rocco Salvatore Calabrò
INTRODUCTION: Currently, none of the available multiple sclerosis (MS) disease-modifying medications has been shown to stop or reverse gait disability. Recently, the nabiximols has been tested for the treatment of spasticity and walking impairment in MS. Nabiximols (trade name Sativex) is an oromucosal spray formulation containing 1:1 fixed ratio of delta-9-tetrahydrocannabinol and cannabidiol derived from cloned Cannabis sativa L. plant. METHOD AND ANALYSIS: A single-center, prospective, parallel design, single-blind trial will be conducted at the IRCCS Neurolesi "Bonino-Pulejo" (Italy) involving MS patients affected by spasticity and undergoing a Robotic Rehabilitation training...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29141811/do-gait-patterns-differ-in-men-and-women-with-multiple-sclerosis
#2
Massimiliano Pau, Federica Corona, Giuseppina Pilloni, Micaela Porta, Giancarlo Coghe, Eleonora Cocco
BACKGROUND: Multiple Sclerosis (MS) affects men and women differently from several points of view: prevalence, severity of cognitive impairments and disability accumulation. However, it is unknown whether ambulatory dysfunctions are sex-related. This study investigated the existence of differences in spatio-temporal and kinematic parameters of gait in men and women with MS using 3D gait analysis. METHODS: Gait patterns of 60 people with MS (pwMS, 32F, 28M) with low to moderate disability (average Expanded Disability Status Scale score 3, range 1-5...
November 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29128525/respiratory-rehabilitation-in-multiple-sclerosis-a-narrative-review-of-rehabilitation-techniques
#3
REVIEW
J Levy, H Prigent, D Bensmail
BACKGROUND: Respiratory disorders in multiple sclerosis (MS) are an important issue. They can occur early during the course of the disease, are associated with the neurological impairment, and can lead to pneumonia and respiratory failure, which are the main causes of death in advanced MS. Prevailing impaired expiratory muscles and cough abilities has been demonstrated in this population and might constitute a specific target for rehabilitation interventions. However, international guidelines lack recommendations regarding respiratory rehabilitation in MS...
November 8, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29120143/restless-legs-syndrome-in-multiple-sclerosis-patients-%C3%A2-patient-experience-at-lipik-special-hospital-for-medical-rehabilitation
#4
Merisanda Časar Rovazdi, Viktor Vidović, Oto Kraml, Vanja Bašić Kes
The study included 60 patients with multiple sclerosis (MS) hospitalized at our institution from September 1 to December 31, 2014. The aim of the study was to assess the prevalence of restless legs syndrome (RLS) in MS patients and RLS relationship with patient age, sex, degree of disability, form of MS, time elapsed from MS diagnosis and use of antidepressants. The diagnosis of RLS was made according to the criteria set by the International Restless Legs Syndrome Study Group. Of the 60 patients, 24 (40%) met the criteria for the existence of RLS...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29119933/pharmacological-and-non-pharmacological-therapies-of-cognitive-impairment-in-multiple-sclerosis
#5
Elzbieta Miller, Agnieszka Morel, Justyna Redlicka, Igor Miller, Joanna Saluk
Cognitive impairment is one of the most important clinical features of neurodegenerative disorders including multiple sclerosis (MS). Conducted research shows that up to 65 percent of MS patients have cognitive deficits such as episodic memory, sustained attention, reduced verbal fluency; however, the cognitive MS domain is information processing speed. It is the first syndrome of cognitive dysfunction and the most widely affected in MS. Occasionally these impairments occur even before the appearance of physical symptoms...
November 9, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/29112939/serious-games-for-arm-rehabilitation-of-persons-with-multiple-sclerosis-a-randomized-controlled-pilot-study
#6
Johanna Jonsdottir, Rita Bertoni, Michael Lawo, Angelo Montesano, Thomas Bowman, Silvia Gabrielli
OBJECTIVES: The feasibility and preliminary evidence for efficacy of a serious games platform compared to exergame using the Wii for arm rehabilitation in persons with multiple sclerosis (MS) was investigated. METHODS: A pilot single-blind randomized (2:1) controlled in clinic trial was carried out. Sixteen persons with MS participated (age years 56.8 (SD 12.3), MS-onset years 19.4 (SD 12.3), EDSS 6.5). Ten participants used a serious games platform (Rehab@Home) while 6 participants played with the commercial Wii platform, for four weeks (40min, 12 sessions/4 weeks)...
October 28, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29111839/the-interpretation-of-physical-activity-exercise-and-sedentary-behaviours-by-persons-with-multiple-sclerosis
#7
Dominique Kinnett-Hopkins, Yvonne Learmonth, Elizabeth Hubbard, Lara Pilutti, Sarah Roberts, Jason Fanning, Thomas Wójcicki, Edward McAuley, Robert Motl
OBJECTIVES: This study adopted a qualitative research design with directed content analysis and examined the interpretations of physical activity, exercise, and sedentary behaviour by persons with multiple sclerosis. METHODS: Fifty three persons with multiple sclerosis who were enrolled in an exercise trial took part in semi-structured interviews regarding personal interpretations of physical activity, exercise, and sedentary behaviours. RESULTS: Forty three percent of participants indicated a consistent understanding of physical activity, 42% of participants indicated a consistent understanding of exercise, and 83% of participants indicated a consistent understanding of sedentary behaviour with the standard definitions...
November 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29111007/performed-and-perceived-walking-ability-in-relation-to-the-expanded-disability-status-scale-in-persons-with-multiple-sclerosis
#8
D Langeskov-Christensen, P Feys, I Baert, M Riemenschneider, E Stenager, U Dalgas
BACKGROUND: The severity of walking impairment in persons with multiple sclerosis (pwMS) at different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is unclear if the EDSS is differently related to performed- and perceived walking capacity tests. AIMS: To quantify walking impairment and perceived impact of MS on walking according to EDSS scores and to examine the relations between these parameters in pwMS. METHODS: EDSS was collected by neurologists and walking was assessed by the timed 25ft walk test (T25FWT), two minute walk test (2MWT), six minute walk test (6MWT) and the 12-item MS walking scale (MSWS-12) in 474 PwMS with mild (EDSS 1-4: n=200) to moderate (EDSS 4...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29109035/-life-behind-the-mask-sexual-life-of-iranian-women-with-multiple-sclerosis
#9
Nahid Dehghan-Nayeri, Zohreh Khakbazan, Faezeh Ghafoori
BACKGROUND: Multiple sclerosis (MS) is a debilitating and life-long disease that affects the sexual life of people. However, in Iran little attention has been paid to the sexual life of women with MS. OBJECTIVE: The aim of this study was to understand the sexual life and experiences of Iranian women with multiple sclerosis. METHODS: A qualitative study was designed, and face-to-face semi-structured interviews were conducted with twenty-five women with MS...
October 26, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29108966/dual-task-of-fine-motor-skill-and-problem-solving-in-individuals-with-multiple-sclerosis-a-pilot-study
#10
Y Goverover, B M Sandroff, J DeLuca
OBJECTIVE: To examine and compare dual-task performance in patients with Multiple Sclerosis (MS) and healthy controls (HC) using mathematical problem-solving questions that included an everyday competence component while performing an upper extremity fine motor task. Additionally, it examined whether difficulties in dual-task performance are associated with problems in performing an everyday internet task. DESIGN: Pilot study, mixed-design with both a within and between subjects' factor PARTICIPANTS: and Setting: Participants included 19 persons with MS and 19 HC who were recruited from a nonprofit rehabilitation research institution and from the community...
November 3, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29102438/prediction-of-falls-in-subjects-suffering-from-parkinson-s-disease-multiple-sclerosis-and-stroke
#11
Ettore Beghi, Elisa Gervasoni, Elisabetta Pupillo, Elisa Bianchi, Angelo Montesano, Irene Aprile, Michela Agostini, Marco Rovaris, Davide Cattaneo
OBJECTIVE: To compare the risk of falls and fall predictors in patients with Parkinson's disease (PD), multiple sclerosis (MS) and stroke using the same study design. DESIGN: Multicenter prospective cohort study. SETTING: Three [masked] institutions for physical therapy and rehabilitation. PARTICIPANTS: Patients with PD, MS and stroke seen for rehabilitation. MAIN OUTCOME MEASURES: Functional scales were applied to investigate balance, disability, daily performance, self-confidence with balance, and social integration...
November 1, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29079869/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-5-fatigue
#12
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079868/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-6-cognitive-dysfunction-and-rehabilitation
#13
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis ("Klinisches Kompetenznetz Multiple Sklerose", KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079866/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-4-sexual-dysfunction-and-eye-movement-disorders
#14
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKNMS) in 2014, several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079865/-what-is-new-in-symptomatic-ms-treatment-part%C3%A2-3-bladder-dysfunction
#15
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKNMS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29076386/impact-of-high-intensity-concurrent-training-on-cardiovascular-risk-factors-in-persons-with-multiple-sclerosis-pilot-study
#16
Charly Keytsman, Dominique Hansen, Inez Wens, Bert O Eijnde
PURPOSE: High-intensity concurrent training positively affects cardiovascular risk factors. Because this was never investigated in multiple sclerosis, the present pilot study explored the impact of this training on cardiovascular risk factors in this population. METHODS: Before and after 12 weeks of high-intense concurrent training (interval and strength training, 5 sessions per 2 weeks, n = 16) body composition, resting blood pressure and heart rate, 2-h oral glucose tolerance (insulin sensitivity, glycosylated hemoglobin, blood glucose and insulin concentrations), blood lipids (high- and low-density lipoprotein, total cholesterol, triglyceride levels) and C-reactive protein were analyzed...
October 27, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29072545/comparison-of-seating-powered-characteristics-and-functions-and-costs-of-electrically-powered-wheelchairs-in-a-general-population-of-users
#17
Michael John Dolan, Megan Jennifer Bolton, Graham Iain Henderson
PURPOSE: To profile and compare the seating and powered characteristics and functions of electrically powered wheelchairs (EPWs) in a general user population including equipment costs. METHOD: Case notes of adult EPW users of a regional NHS service were reviewed retrospectively. Seating equipment complexity and type were categorized using the Edinburgh classification. Powered characteristics and functions, including control device type, were recorded. RESULTS: 482 cases were included; 53...
October 26, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29072042/active-exergames-to-improve-cognitive-functioning-in-neurological-disabilities-a-systematic-review-and-meta-analysis
#18
Gioia Mura, Mauro G Carta, Federica Sancassiani, Sergio Machado, Luca Prosperini
INTRODUCTION: Exergames represent a way to perform physical activity through active video games, serving as potentially useful tool in the field of neurorehabilitation. However, little is known regarding the possible role of exergames in improving cognitive functions in persons suffering from neurological disabilities. EVIDENCE ACQUISITION: A search for relevant articles was carried out on PubMed/Medline, Scopus, PEDro, and Google Scholar. Only randomized controlled studies and non-randomized but controlled studies were retained...
October 25, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29070966/psychometric-properties-of-a-clinical-strength-assessment-protocol-in-people-with-multiple-sclerosis
#19
Mark M Mañago, Jeffrey R Hebert, Margaret Schenkman
BACKGROUND: Strength training in people with multiple sclerosis (MS) is an important component of rehabilitation, but it can be challenging for clinicians to quantify strength accurately and reliably. This study investigated the psychometric properties of a clinical strength assessment protocol using handheld dynamometry and other objective, quantifiable tests for the lower extremities and trunk in people with MS. METHODS: This study determined discriminant validity between 25 participants with MS and 25 controls and between participants with MS who had higher versus lower disability; test-retest reliability across 7 to 10 days; and response stability...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070965/validity-and-reliability-of-four-clinical-gait-measures-in-patients-with-multiple-sclerosis
#20
Susan E Bennett, Lacey E Bromley, Nadine M Fisher, Machiko R Tomita, Paulette Niewczyk
BACKGROUND: The gold standards for assessing ambulation are the Expanded Disability Status Scale (EDSS) and the Timed 25-Foot Walk (T25FW) test. In relation with these measures, we assessed the reliability and validity of four clinical gait measures: the Timed Up and Go (TUG) test, the Dynamic Gait Index (DGI), the 2-Minute Walk Test (2MWT), and the 6-Minute Walk Test (6MWT). Patient self-report of gait was also assessed using the 12-item Multiple Sclerosis Walking Scale (MSWS-12). METHODS: Individuals 20 years or older with a diagnosis of multiple sclerosis (MS) and an EDSS score of 2...
September 2017: International Journal of MS Care
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