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https://www.readbyqxmd.com/read/29776774/association-of-disrupted-circadian-rhythmicity-with-mood-disorders-subjective-wellbeing-and-cognitive-function-a-cross-sectional-study-of-91-105-participants-from-the-uk-biobank
#1
Laura M Lyall, Cathy A Wyse, Nicholas Graham, Amy Ferguson, Donald M Lyall, Breda Cullen, Carlos A Celis Morales, Stephany M Biello, Daniel Mackay, Joey Ward, Rona J Strawbridge, Jason M R Gill, Mark E S Bailey, Jill P Pell, Daniel J Smith
BACKGROUND: Disruption of sleep and circadian rhythmicity is a core feature of mood disorders and might be associated with increased susceptibility to such disorders. Previous studies in this area have used subjective reports of activity and sleep patterns, but the availability of accelerometer-based data from UK Biobank participants permits the derivation and analysis of new, objectively ascertained circadian rhythmicity parameters. We examined associations between objectively assessed circadian rhythmicity and mental health and wellbeing phenotypes, including lifetime history of mood disorder...
May 15, 2018: Lancet Psychiatry
https://www.readbyqxmd.com/read/29775085/usage-of-therapeutic-sleep-deprivation-a-survey-in-psychiatric-hospitals-in-austria-germany-and-switzerland
#2
Dietmar Winkler, Marie Spies, Yasmin Al-Resheg, Joseph C Wu, William E Bunney, Blynn G Bunney, Siegfried Kasper, Edda Pjrek
OBJECTIVE: Therapeutic sleep deprivation (SD) is a nonpharmacological treatment that is used most often for depression. The aim of this study was to examine the pattern of use of SD in psychiatric hospitals in Austria, Germany, and Switzerland. METHODS: A questionnaire about perceived usage of SD was sent by mail to all 511 psychiatric hospitals in the three countries. Nonresponders were asked to answer the questionnaire by phone. We achieved a response rate of 75...
May 18, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29773948/the-impact-of-total-sleep-deprivation-upon-cognitive-functioning-in-firefighters
#3
Sławomir Kujawski, Joanna Słomko, Małgorzata Tafil-Klawe, Monika Zawadka-Kunikowska, Justyna Szrajda, Julia L Newton, Paweł Zalewski, Jacek J Klawe
Introduction: Firefighters as a profession are required to maintain high levels of attention for prolonged periods. However, total sleep deprivation (TSD) could influence negatively upon performance, particularly when the task is prolonged and repetitive. Purpose: The aim of this study is to examine the influence of TSD on cognitive functioning in a group of firefighters. Subjects and methods: Sixty volunteers who were active male fire brigade officers were examined with a computerized battery test that consisted of simple reaction time (SRT) (repeated three times), choice reaction time, visual attention test, and delayed matching to sample...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29773830/circadian-and-homeostatic-modulation-of-multi-unit-activity-in-midbrain-dopaminergic-structures
#4
Karim Fifel, Johanna H Meijer, Tom Deboer
Although the link between sleep disturbances and dopamine (DA)-related neurological and neuropsychiatric disorders is well established, the impact of sleep alterations on neuronal activity of midbrain DA-ergic structures is currently unknown. Here, using wildtype C57Bl mice, we investigated the circadian- and sleep-related modulation of electrical neuronal activity in midbrain ventral-tegmental-area (VTA) and substantia nigra (SN). We found no significant circadian modulation of activity in SN while VTA displayed a low amplitude but significant circadian modulation with increased firing rates during the active phase...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29772994/improvement-in-sleep-quality-after-carpal-tunnel-release
#5
Arie G Trouw, Ashish Patel, Andrew Yang, Julio Jauregui, Daniel Caligiuri, Jack Choueka
Carpal tunnel syndrome (CTS) has multiple implications on patient quality of life. In particular, CTS may affect quality of sleep, causing sleep deprivation in extreme cases. Carpal tunnel release (CTR) surgery may aid in resolving these disturbances. The purpose of our study was to investigate whether patients who have undergone CTR have improved sleep quality and to determine the timeline for such improvement. Twenty-one patients were prospectively enrolled and followed-up for two years. They were asked to complete a Pittsburgh Sleep Quality Index (PSQI), a pain visual analog scale (VAS), a sleep perception VAS, and both components Symptom Severity and Functional Status Scale from the Levine-Katz carpal tunnel questionnaire...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29772442/cognitive-and-hippocampus-biochemical-changes-following-sleep-deprivation-in-the-adult-male-rat
#6
Ebrahim Nabaee, Mahnaz Kesmati, Ali Shahriari, Lotfollah Khajehpour, Mozhgan Torabi
Sleep deprivation (SD) influences physiological processes such as cognitive function. The balance of oxidant and antioxidant markers, neurotrophic factors and magnesium are affected by sleep deprivation but there is no difference between pre and post training sleep deprivation. This study was designed to investigate memory retrieval and biochemical factors such as oxidant and antioxidant enzyme, brain-derived neurotrophic factor (BDNF) and magnesium levels in the hippocampus following pre and post-training sleep deprivation...
May 14, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29767030/commentary-sleep-deprivation-promotes-habitual-control-over-goal-directed-control-behavioral-and-neuroimaging-evidence
#7
COMMENT
Yannick Boddez, Eike K Buabang, Ann-Kathrin Zenses, Mathilde Descheemaeker
No abstract text is available yet for this article.
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29764214/chronotype-influences-response-to-antidepressant-chronotherapeutics-in-bipolar-patients
#8
Sara Dallaspezia, Masahiro Suzuki, Locatelli Clara, Cristina Colombo, Francesco Benedetti
Patient diurnal mood fluctuation, sleep characteristics and factors affecting sleep homeostasis predict antidepressant response to the combination of total sleep deprivation and light therapy (TSD + LT). In order to study if chronotype could influence response to TSD+LT, we considered 194 bipolar depressed patients. Severity of depression was rated with Hamilton Depression Rating Scale; perceived mood levels were assessed by a self-administered 10-cm visual analogue scale and chronotype was assessed using the Mornigness-Eveningness Questionnaire...
May 15, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29750922/legal-aspects-of-sleep-medicine-in-the-21-st-century
#9
REVIEW
Saiprakash B Venkateshiah, Romy Hoque, Nancy A Collop
Multiple manifestations of sleep disorders may interact with the law making it important to increase awareness of such interactions among clinicians. Patients with excessive sleepiness may have civil (and in some states criminal) liability if they fall asleep while driving and cause a motor vehicle accident. Employers may be held vicariously liable due to the actions of sleepy employees. Hence awareness of causes of excessive sleepiness such as sleep deprivation and OSA is increasing among trucking, railroad, and other safety sensitive occupations...
May 8, 2018: Chest
https://www.readbyqxmd.com/read/29748772/decreased-cortical-and-subcortical-response-to-inhibition-control-after-sleep-deprivation
#10
Rui Zhao, Xinxin Zhang, Ningbo Fei, Yuanqiang Zhu, Jinbo Sun, Peng Liu, Xuejuan Yang, Wei Qin
The effects of sleep deprivation (SD) on the neural substrates of inhibition control are poorly understood. Here we used functional magnetic resonance imaging to examine the effects of 24 h of SD on cerebral activation during a stop-signal task in 20 normal young subjects. Behaviorally, subjects showed significantly delayed stop-signal reaction time (SSRT) following SD. In addition, reduced cerebral activation was found in the "stopping network" (including the inferior frontal gyrus [IFG], supplementary motor area, subthalamic nucleus [STN] and insula) and vision-related regions (occipital cortex, lingual gyrus and fusiform gyrus) after SD...
May 10, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29746721/melatonin-for-the-promotion-of-sleep-in-adults-in-the-intensive-care-unit
#11
REVIEW
Sharon R Lewis, Michael W Pritchard, Oliver J Schofield-Robinson, Phil Alderson, Andrew F Smith
BACKGROUND: Patients in the intensive care unit (ICU) experience sleep deprivation caused by environmental disruption, such as high noise levels and 24-hour lighting, as well as increased patient care activities and invasive monitoring as part of their care. Sleep deprivation affects physical and psychological health, and patients perceive the quality of their sleep to be poor whilst in the ICU. Artificial lighting during night-time hours in the ICU may contribute to reduced production of melatonin in critically ill patients...
May 10, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29745915/association-of-diabetes-compensation-with-sleeping-habits-and-well-being-in-patients-with-diabetes-mellitus
#12
L Navasardyan, A Аvetisyan, M Simonyan, E Aghajanova
Recent data estimates that sleep deprivation and poor quality of night sleep have an impact on the incidence and prevalence of both obesity and type 2 diabetes, as well as cardiovascular events in all ages. The aim of this work is to evaluate the association between diabetes compensation and sleep quality and quantity, comparing patients with type 1 and type 2 diabetes, as well as to establish any potential connection with "screen" time, physical activity and well-being. For this reason 49 patients with type 1 (n=28) and type 2 DM (n=21) were investigated...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29741724/myelin-modifications-after-chronic-sleep-loss-in-adolescent-mice
#13
Michele Bellesi, John Douglas Haswell, Luisa de Vivo, William Marshall, Patrick H Roseboom, Giulio Tononi, Chiara Cirelli
Study Objectives: Previous studies found that sleep loss can suppress the expression of genes implicated in myelination and can have adverse effects on oligodendrocyte precursor cells. On the other hand, sleep may favor myelination by promoting the expression of genes involved in its formation and maintenance. Albeit limited, these results suggest that sleep loss can have detrimental effects on the formation and maintenance of myelin. Methods: Here, we tested this hypothesis by evaluating ultrastructural modifications of myelin in two brain regions (corpus callosum and lateral olfactory tract) of mice exposed to different periods of sleep loss, from a few hours of sleep deprivation to ~5 days of chronic sleep restriction...
May 1, 2018: Sleep
https://www.readbyqxmd.com/read/29739334/exploring-gene-expression-biomarker-candidates-for-neurobehavioral-impairment-from-total-sleep-deprivation
#14
Hilary A Uyhelji, Doris M Kupfer, Vicky L White, Melinda L Jackson, Hans P A Van Dongen, Dennis M Burian
BACKGROUND: Although sleep deprivation is associated with neurobehavioral impairment that may underlie significant risks to performance and safety, there is no reliable biomarker test to detect dangerous levels of impairment from sleep loss in humans. This study employs microarrays and bioinformatics analyses to explore candidate gene expression biomarkers associated with total sleep deprivation (TSD), and more specifically, the phenotype of neurobehavioral impairment from TSD. Healthy adult volunteers were recruited to a sleep laboratory for seven consecutive days (six nights)...
May 9, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29737605/chronic-high-caloric-diet-modifies-sleep-homeostasis-in-mice
#15
Maria Panagiotou, Johanna H Meijer, Tom Deboer
Obesity prevalence and sleep habit changes are commonplace nowadays, due to modern lifestyle. A bidirectional relationship likely exists between sleep quality and metabolic disruptions, that could impact quality of life. In our study, we investigated the effects of a chronic high-caloric diet on sleep architecture and sleep regulation in mice. We studied the effect of three months high-caloric diet (HCD, 45% fat) on sleep and the sleep electroencephalogram (EEG) in C57BL/6J mice during 24-h baseline (BL) recordings, and after 6-h sleep deprivation (SD)...
May 8, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29737095/-prevalence-and-determinants-of-depressive-symptoms-in-middle-and-senior-aged-populations-with-visual-impairment
#16
Zhan Yang, Yin Liu, Wen-Jie Zhang, Ning-Xiu Li
OBJECTIVE: To determine the prevalence and determinants of depressive symptoms in visually impaired mid- and old-aged populations. METHODS: Data were extracted from the 2013 China Health and Retirement Longitudinal Study database. A total of 1 462 mid- and old-aged respondents reported visual problems. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression (CES-D) scale. Chi-square tests and binary logistic regression analyses were performed to identify factors associated with the prevalence of depressive symptoms...
January 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29736355/juvenile-myoclonic-epilepsy-presenting-with-neurocognitive-impairment-a-case-report
#17
Sarfraz Mahesar, Hira F Akbar, Husnain Abid, Rabia Sana
Juvenile myoclonic epilepsy (JME) is a genetically and clinically diverse disorder which is characterized by myoclonic jerks, usually after awakening from sleep. It affects both genders equally and manifests during the second decade of life. The various precipitating factors include stress, light, sleep deprivation, and alcohol. A history of morning clumsiness supported by typical electroencephalography (EEG) findings, together with a normal clinical examination all point towards a diagnosis of JME. We present the case of a nine-year-old girl who presented with cognitive dysfunction in addition to myoclonic jerks...
March 5, 2018: Curēus
https://www.readbyqxmd.com/read/29734983/the-effects-of-experimental-sleep-fragmentation-and-sleep-deprivation-on-the-response-of-the-genioglossus-muscle-to-inspiratory-resistive-loads
#18
Jennifer M Cori, Christian L Nicholas, Joanne Avraam, V Vien Lee, Rachel Schembri, Melinda L Jackson, Amy S Jordan
STUDY OBJECTIVES: Poor upper airway dilator muscle function may contribute to obstructive sleep apnea (OSA). Sleep deprivation reduces dilator muscle responsiveness, but sleep fragmentation, which is most characteristic of OSA, has not been assessed. This study compared the effects of sleep deprivation and fragmentation on dilator muscle responsiveness during wakefulness. METHOD: Twenty-four healthy individuals (10 female) participated in two consecutive overnight polysomnography (PSG) sessions...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29727778/differences-in-sensory-reweighting-due-to-loss-of-visual-and-proprioceptive-cues-in-postural-stability-support-among-sleep-deprived-cadet-pilots
#19
Shan Cheng, Jin Ma, Jicheng Sun, Jian Wang, Xiao Xiao, Yihan Wang, Wendong Hu
BACKGROUND: Sleep deprivation is known to diminish postural control. RESEARCH QUESTION: We investigated whether sleep deprivation affects sensory reweighting for postural control due to loss of visual and proprioceptive cues. METHODS: Two cohorts of cadet pilots were deprived of sleep for 40 h. Variabilty in force-platform center of pressure was analyzed based on the whole path length (WPL); circumference area (CA); mean of displacement along x and y axes and corresponding standard deviations (SDx, SDy); and frequency of body-sway intensity, all of which were recorded while the cadets stood with eyes open (NEO), eyes closed (NEC), and eyes closed on a foam platform base (FEC) A sleepiness index (SUBI) based on principal component analysis of selected Cohort 1 data (n = 37) was used to compare Cohort 2 data (n = 29) with scores for the Stanford Sleepiness Scale (SSS) and Pittsburg Sleep Quality Index (PSQI)...
April 26, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29726694/the-role-of-the-nervous-system-in-neuromuscular-fatigue-induced-by-ultra-endurance-exercise
#20
Guillaume Y Millet, Vincent Martin, John Temesi
Ultra-endurance events are not a recent development but they have only become very popular in the last two decades, particularly ultra-marathons run on trails. The present paper reviews the role of the central nervous system (CNS) in neuromuscular fatigue induced by ultra-endurance exercise. Large decreases in voluntary activation are systematically found in ultra-endurance running but are attenuated in ultra-endurance cycling for comparable intensity and duration. This indirectly suggests that afferent feedback, rather than neurobiological changes within the CNS, is determinant in the amount of central fatigue produced...
May 4, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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