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https://www.readbyqxmd.com/read/28324995/eeg-based-mental-fatigue-detection-by-spectral-non-negative-matrix-factorization
#1
Lili Li, Guanghua Xu, Jun Xie, Min Li, Sicong Zhang, Ailing Luo
After long time cognitive work, most of people confronted with the mental fatigue, which can decrease the classification accuracy of cognitive, or even cause the traffic accidents for drivers. Therefore, the detection of the fatigue state is very essential. The study aims to explore an effective and novel approach based on electroencephalogram. All participants were instructed to implement the spelling experiments. Data were recorded on the awake condition, on sleep deprivation condition and after two hour spelling experiment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28318321/social-jet-lag-sleep-corrected-formula
#2
Konrad S Jankowski
Social jet lag is a term describing misalignment between social and biological times. In this article, it is argued that the currently used formula for social jet lag captures not only this misalignment, but also sleep debt resulting from sleep deprivation during workdays. It is proposed to adopt the sleep-corrected formula for social jet lag, which takes the form of the difference between the sleep onset on free days and workdays in the case of subjects with longer sleep and later (or equal) sleep onset on free days compared to workdays; it takes the form of the difference between the sleep offset on free days and workdays for subjects with longer sleep and earlier (or equal) sleep offset on workdays compared to free days...
March 20, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28315757/chronic-social-stress-leads-to-altered-sleep-homeostasis-in-mice
#3
Nadja Olini, Iru Rothfuchs, Damiano Azzinnari, Christopher R Pryce, Salome Kurth, Reto Huber
Disturbed sleep and altered sleep homeostasis are core features of many psychiatric disorders such as depression. Chronic uncontrollable stress is considered an important factor in the development of depression, but little is known on how chronic stress affects sleep regulation and sleep homeostasis. We therefore examined the effects of chronic social stress (CSS) on sleep regulation in mice. Adult male C57BL/6 mice were implanted for electrocortical recordings (ECoG) and underwent either a 10-day CSS protocol or control handling (CON)...
March 15, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28314820/amyloid-precursor-protein-in-drosophila-glia-regulates-sleep-and-genes-involved-in-glutamate-recycling
#4
Abud Jose Farca Luna, Magali Perier, Laurent Seugnet
The Amyloid Precursor Protein (App) plays a crucial role in Alzheimer disease (AD) via the production and deposition of toxic β-amyloid peptides. App is heavily expressed in neurons where the vast majority of studies investigating its function have been carried out, while almost nothing is known about its function in glia, where it is also expressed, and can potentially participate in the regulation of neuronal physiology. In this report, we investigated whether Appl, the Drosophila homolog of App, could influence sleep-wake regulation when its function is manipulated in glial cells...
March 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28314522/increased-photosensitivity-following-short-sleep-in-sleep-deprived-patients
#5
Ayşe Deniz Elmalı, Hatice Kurucu, Özdem Ertürk Çetin, Özlem Çokar, Zeliha Matur, Ayşin Dervent, Gülçin Benbir Şenel, Candan Gürses, Veysi Demirbilek
INTRODUCTION: We aimed to determine the effect of short day-time sleep on photoparoxysmal epileptic activity in sleep-deprived patients. METHODS: We retrospectively reviewed video-EEG recordings performed between 2003 and 2015. All recordings following at least four hours of sleep deprivation, including intermittent photic stimulation (IPS) both before and after sleep with any form of epileptiform activity were included. The study group was divided into four subgroups: (1) no photoparoxysmal response (PPR) group, with epileptiform activities other than PPRs; (2) increment group, with PPR duration increased by ≥200% after vs...
March 14, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28304302/sleep-deprivation-induced-plasma-amyloid-%C3%AE-transport-disturbance-in-healthy-young-adults
#6
Meng Wei, Beiyu Zhao, Kang Huo, Yongning Deng, Suhang Shang, Jie Liu, Yanbo Li, Louyan Ma, Yu Jiang, Liangjun Dang, Chen Chen, Shan Wei, Juanli Zhang, Hailei Yang, Fan Gao, Qiumin Qu
BACKGROUND: Sleep is an important physiological process and beneficial in the removal of brain metabolites and functional recovery. Prior studies have shown that sleep disorders are significant risk factors for Alzheimer's disease (AD). OBJECTIVE: The present study was designed to characterize the effect of short-term total sleep deprivation (TSD) on plasma amyloid-β (Aβ) concentrations. METHODS: A clinical trial was conducted between March 1, 2016, and April 1, 2016...
March 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28303126/the-influence-of-host-stress-on-the-mechanism-of-infection-lost-microbiomes-emergent-pathobiomes-and-the-role-of-interkingdom-signaling
#7
John C Alverdy, James N Luo
Mammals constantly face stressful situations, be it extended periods of starvation, sleep deprivation from fear of predation, changing environmental conditions, or loss of habitat. Today, mammals are increasingly exposed to xenobiotics such as pesticides, pollutants, and antibiotics. Crowding conditions such as those created for the purposes of meat production from animals or those imposed upon humans living in urban environments or during world travel create new levels of physiologic stress. As such, human progress has led to an unprecedented exposure of both animals and humans to accidental pathogens (i...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28302573/stair-walking-is-more-energizing-than-low-dose-caffeine-in-sleep-deprived-young-women
#8
Derek D Randolph, Patrick J O'Connor
INTRODUCTION: The acute energizing effect of exercise and caffeine has never been examined in a single study of adults with chronic sleep deprivation but evidence from a study of this type could help individuals choose between these two common alertness-enhancing options. AIM: The apriori primary aim of this experiment was to compare the influence of 10-min of low-to-moderate intensity stair walking to the consumption of capsules containing 50mg caffeine or flour (placebo) on feelings of energy in physically active, college female caffeine users with chronic insufficient sleep...
March 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28300651/sleep-fragmentation-hypersensitizes-healthy-young-women-to-deep-and-superficial-experimental-pain
#9
Stella Iacovides, Kezia George, Peter Kamerman, Fiona C Baker
The effect of sleep deprivation on pain sensitivity has typically been studied using total and partial sleep deprivation protocols. These protocols do not mimic the fragmented pattern of sleep disruption usually observed in individuals with clinical pain conditions. Therefore, we conducted a controlled-experiment to investigate the effect of sleep fragmentation on pain perception (deep pain: forearm muscle ischaemia, and superficial pain: graded pin-pricks applied to the skin) in 11 healthy young women following two consecutive nights of sleep fragmentation, compared with a normal night of sleep...
March 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28300056/imbalance-between-tnf%C3%AE-and-progranulin-contributes-to-memory-impairment-and-anxiety-in-sleep-deprived-mice
#10
Kun Zhang, Yu-Jiao Li, Dan Feng, Peng Zhang, Ya-Tao Wang, Xiang Li, Shui-Bing Liu, Yu-Mei Wu, Ming-Gao Zhao
Sleep disorder is becoming a widespread problem in current society, and is associated with impaired cognition and emotional disorders. Progranulin (PGRN), also known as granulin epithelin precursor, promotes neurite outgrowth and cell survival, and is encoded by the GRN gene. It is a tumor necrosis factor α receptor (TNFR) ligand which is implicated in many central nervous system diseases. However, the role PGRN in sleep disorder remains unclear. In the present study, we found that sleep deprivation (S-DEP) impaired the memory and produced thigmotaxis/anxiety-like behaviors in mice...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28299422/homeostatic-regulation-through-gaba-and-acetylcholine-muscarinic-receptors-of-motor-trigeminal-neurons-following-sleep-deprivation
#11
Hanieh Toossi, Esther Del Cid-Pellitero, Barbara E Jones
Muscle tone is regulated across sleep-wake states, being maximal in waking, reduced in slow wave sleep (SWS) and absent in paradoxical or REM sleep (PS or REMS). Such changes in tone have been recorded in the masseter muscles and shown to correspond to changes in activity and polarization of the trigeminal motor 5 (Mo5) neurons. The muscle hypotonia and atonia during sleep depend in part on GABA acting upon both GABAA and GABAB receptors (Rs) and acetylcholine (ACh) acting upon muscarinic 2 (AChM2) Rs. Here, we examined whether Mo5 neurons undergo homeostatic regulation through changes in these inhibitory receptors following prolonged activity with enforced waking...
March 15, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28294068/cognitive-impacts-of-estrogen-treatment-in-androgen-deprived-males-what-needs-to-be-resolved
#12
Erik Wibowo
BACKGROUND: Many prostate cancer (PCa) patients are on androgen deprivation therapy (ADT) as part of their cancer treatments but ADT may cause cognitive impairments. ADT depletes men of both androgen and estrogen. Whether estradiol supplementation can improve cognitive impairments in patients on ADT is understudied. OBJECTIVE: To summarize data on the effects of estradiol treatment on cognitive function of androgen-deprived genetic male populations (PCa patients and male-to-female transsexuals) and castrated male animals...
March 13, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28284888/characteristics-of-sleep-in-socially-vulnerable-adolescents
#13
Lisie Polita Romanzini, Aline Ávila Dos Santos, Magda Lahorgue Nunes
IMPORTANCE: This study may help understand the effects of an unfavorable environment in sleep quality of adolescents. OBJECTIVE: To investigate sleep quality in socially vulnerable adolescents, correlating the results with cognitive problems and attention deficit/hyperactivity disorder, and assessing the effectiveness of sleep hygiene and an educational intervention. DESIGN: Cross-sectional and interventional study. SETTING: an educational charitable center supported by a Catholic institution, in Porto Alegre, southern Brazil...
January 6, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28275652/altered-sleep-and-eeg-power-in-the-p301s-tau-transgenic-mouse-model
#14
Jerrah K Holth, Thomas E Mahan, Grace O Robinson, Andreia Rocha, David M Holtzman
OBJECTIVE: Sleep disturbances are prevalent in human tauopathies yet despite the importance of sleep, little is known about its relationship with tau pathology. Here, we investigate this interaction by analyzing sleep and tau pathology throughout tauopathy disease progression in P301S human tau transgenic mice. METHODS: P301S and wild-type mice were analyzed by electroencephalography (EEG)/electromyography at 3, 6, 9, and 11 months of age for sleep/wake time, EEG power, and homeostatic response...
March 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28273216/sleep-deprivation-and-drowsiness-of-medical-residents-and-medical-students
#15
Kátia Sheylla Malta Purim, Ana Tereza Bittencourt Guimarães, Ana Cláudia Kapp Titski, Neiva Leite
OBJECTIVE: to evaluate sleep quality and daytime sleepiness of residents and medical students. METHODS: we applied a socio-demographic questionnaire, the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS) to a population of residents and medical students. RESULTS: hundred five residents and 101 undergraduate medical students participated. Residents presented higher mean PSQI (6.76±2.81) with poorer sleep quality when compared with undergraduates (5...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28272914/chronotype-class-times-and-academic-achievement-of-university-students
#16
Tristan Enright, Roberto Refinetti
Numerous studies over the years have documented an effect of human chronotypes on physiological and psychological processes. Studies evaluating the impact of an individual's chronotype on his/her academic achievement have indicated that morning chronotypes have an academic advantage over evening chronotypes. However, these studies did not account for the time of day in which the participants were being evaluated. The goal of the present study was to examine whether morning chronotypes do have an academic advantage over evening chronotypes when the time of day of classes and exams is taken into consideration...
March 8, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28269604/effects-of-high-frequency-rtms-on-sleep-deprivation-a-pilot-study
#17
D P Martinez-Cancino, J Azpiroz-Leehan, L Jimenez-Angeles, A Garcia-Quintanar, R Santana-Miranda
Transcranial magnetic stimulation is a neurostimulation technique which has the potential to serve as a unique research tool for investigating a wide variety of fields in cognitive neuroscience. TMS has been approved by the FDA to serve as a treatment to depression and has also been used to evaluate its effects among several conditions such as Alzheimer, Parkinson disease, chronic pain and stroke. High frequency TMS has been previously used with the intention to measure and modulate the negative effects of sleep deprivation in cognitive performance, but there is no consensus about the ideal protocol yet...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267366/eveningness-associates-with-smoking-and-sleep-problems-among-pregnant-women
#18
Ilona Merikanto, E Juulia Paavonen, Outi Saarenpää-Heikkilä, Tiina Paunio, Timo Partonen
Sleep problems during pregnancy impair maternal health and increase the risk for adverse pregnancy outcome. The circadian preference toward eveningness has been associated with sleep problems in previous studies. Here, we studied whether evening-type women had more sleep problems during their pregnancy, as compared with other chronotypes, in a sample consisting of 1653 pregnant women from the Finnish CHILD-SLEEP Birth Cohort. Chronotype was assessed with a shortened version of the morningness-eveningness questionnaire...
March 7, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28257638/sleep-habits-and-pattern-in-1-14-years-old-children-and-relationship-with-video-devices-use-and-evening-and-night-child-activities
#19
Paolo Brambilla, Marco Giussani, Angela Pasinato, Leonello Venturelli, Francesco Privitera, Emanuele Miraglia Del Giudice, Sara Sollai, Marina Picca, Giuseppe Di Mauro, Oliviero Bruni, Elena Chiappini
BACKGROUND: Sleep in childhood and adolescence is crucial for mental and physical health; however several researches reported an increasing trend towards a sleep deprivation in this age. Due to the lack of recent epidemiological studies in Italy, the aim of our study was to depict sleep habits and patterns in Italian children aged 1-14 years and to evaluate their relationships with video devices use (TV, tablet, smartphone, PC) and evening/night child activities. METHODS: A structured interview was conducted during 2015 by 72 Family Pediatricians in 2030 healthy children aged 1-14 years by a cross-sectional survey named "Ci piace sognare"...
January 13, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28255162/differences-in-electroencephalographic-non-rapid-eye-movement-sleep-slow-wave-characteristics-between-young-and-old-mice
#20
Maria Panagiotou, Vladyslav V Vyazovskiy, Johanna H Meijer, Tom Deboer
Changes in sleep pattern are typical for the normal aging process. However, aged mice show an increase in the amount of sleep, whereas humans show a decrease when aging. Mice are considered an important model in aging studies, and this divergence warrants further investigation. Recently, insights into the network dynamics of cortical activity during sleep were obtained by investigating characteristics of individual electroencephalogram (EEG) slow waves in young and elderly humans. In this study, we investigated, for the first time, the parameters of EEG slow waves, including their incidence, amplitude, duration and slopes, in young (6 months) and older (18-24 months) C57BL/6J mice during undisturbed 24 h, and after a 6-h sleep deprivation (SD)...
March 3, 2017: Scientific Reports
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