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https://www.readbyqxmd.com/read/27925459/quantification-of-type-timing-and-extent-of-cell-body-and-nucleus-deformations-caused-by-the-dimensions-and-hydrophilicity-of-square-prism-micropillars
#1
Onur Hasturk, Abdullah Sivas, Bulent Karasozen, Utkan Demirci, Nesrin Hasirci, Vasif Hasirci
Novel digital analysis strategies are developed for the quantification of changes in the cytoskeletal and nuclear morphologies of mesenchymal stem cells cultured on micropillars. Severe deformations of nucleus and distinct conformational changes of cell body ranging from extensive elongation to branching are visualized and quantified. These deformations are caused mainly by the dimensions and hydrophilicity of the micropillars.
December 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27922344/predictors-of-mortality-in-a-paediatric-intensive-care-unit-in-kigali-rwanda
#2
Rosine Nyirasafari, Mark H Corden, Angélique Charlie Karambizi, Jean Claude Kabayiza, Jean Damascene Makuza, Rex Wong, Michael F Canarie
BACKGROUND: The enormous burden of critical illness in resource-limited settings has led to a growing interest in paediatric critical care in these regions. However, published data on the practice of critical care and patient outcomes in these settings are scant. OBJECTIVE: This study sought to identify risk factors associated with mortality in the newly established Paediatric Intensive Care Unit (PICU) at Kigali University Teaching Hospital (KUTH) in Rwanda and test the predictive ability of a newly devised mortality risk score, the modified PRISM (MP) score...
December 6, 2016: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/27921322/the-heterophoria-of-3-5-year-old-children-as-a-function-of-viewing-distance-and-target-type
#3
Mary E Troyer, Vidhyapriya Sreenivasan, T J Peper, T Rowan Candy
PURPOSE: Heterophoria is the misalignment of the eyes in monocular viewing and represents the accuracy of vergence driven by all classical cues except disparity. It is challenging to assess restless children using clinical cover tests, and phoria in early childhood is poorly understood. Here we used eye tracking to assess phoria as a function of viewing distance and target in adults and young children, with comparison to clinical cover tests. METHODS: Purkinje image tracking (MCS PowerRefractor) was used to record eye alignment in adults (19-28 years, N = 24) and typically developing children (3-5 years, N = 24)...
December 5, 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27920910/crystal-structure-of-tibi2
#4
Kei Watanabe, Hisanori Yamane
Black granular single crystals of monotitanium dibismuth, TiBi2, were synthesized by slow cooling of a mixture of Bi and Ti from 693 K. The title compound is isostructural with CuMg2 (ortho-rhom-bic Fddd symmetry). Ti atoms are located in square anti-prisms of Bi atoms. The network of one type of Bi atom spirals along the a-axis direction while honeycomb layers of the other type of Bi atom spreading in the ab plane inter-lace one another.
September 1, 2016: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/27920496/fabrication-of-anti-vitiligo-ointment-containing-psoralea-corylifolia-in-vitro-and-in-vivo-characterization
#5
Irshad Hussain, Nisar Hussain, Abdul Manan, Abdur Rashid, Barkat Khan, Sattar Bakhsh
BACKGROUND: Vitiligo is a repugnant and odious dermatological malady of the time. It has an detrimental impact on the pigmentation of the human skin as a result of the destruction of cutaneous melanocytes. It affects 1%-2% of the population worldwide. Different therapeutic regimens have been deployed to treat vitiligo, but none of them could stand alone to be stated as a perfect cure. Recently, a change has been observed through novel experimental-designed optimization leading to the development of an anti-vitiligo ointment containing Psoralea corylifolia (PC) seed powder...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27919101/the-risk-of-pedestrian-collisions-with-peripheral-visual-field-loss
#6
Eli Peli, Henry Apfelbaum, Eliot L Berson, Robert B Goldstein
Patients with peripheral field loss complain of colliding with other pedestrians in open-space environments such as shopping malls. Field expansion devices (e.g., prisms) can create artificial peripheral islands of vision. We investigated the visual angle at which these islands can be most effective for avoiding pedestrian collisions, by modeling the collision risk density as a function of bearing angle of pedestrians relative to the patient. Pedestrians at all possible locations were assumed to be moving in all directions with equal probability within a reasonable range of walking speeds...
December 1, 2016: Journal of Vision
https://www.readbyqxmd.com/read/27918498/introducing-the-acoustic-prism
#7
Knvul Sheikh
No abstract text is available yet for this article.
October 18, 2016: Scientific American
https://www.readbyqxmd.com/read/27915155/vertically-oriented-structure-and-its-fracture-behavior-of-the-indonesia-white-pearl-oyster
#8
Guowei Chen, Hongyun Luo, Shunfei Luo, Zhenying Lin, Yue Ma
Structural calcites, aragonites, and the bonding organic network decide the growth, structure and mechanical properties of the mollusk bivalvia shell. Here, it was found out that the calcite prisms together with the coated organics construct another kind of 'brick and mortar' structure similar to the aragonite tablets. The calcite layer can be divided into three sublayers and direct evidences show that the calcite prisms are produced by two methods: nucleation and growing in the first sublayer; or fusing from the aragonites, which is quite different from some previous reports...
November 3, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27913778/effect-of-deslorelin-acetate-treatment-in-oocyte-recovery-and-in-vitro-embryo-production-in-domestic-cats
#9
Camila Louise Ackermann, Eduardo Trevisol, Leticia Ferrari Crocomo, Tatiana da Silva Rascado, Rodrigo Volpato, Carlos Renato de Freitas Guaitolini, Carlize Lopes, Talita de Almeida Costa, Maria Denise Lopes
OBJECTIVES: The present study investigated the effect of contraceptive treatment with deslorelin acetate on in vitro embryo production and oocyte recovery in domestic queens. METHODS: Twenty-one mature domestic cats were used. Eleven queens (treated group) and one tom were kept in an experimental cattery, and 10 queens were privately owned (control group). When in interestrus or diestrus (day 0) a deslorelin acetate implant (Suprelorin, 4.7 mg/animal) was inserted into the subcutaneous tissue of the interscapular region in all queens in the treated group...
December 2, 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27912974/pulmonary-function-and-nutritional-morbidity-in-children-and-adolescents-with-congenital-diaphragmatic-hernia
#10
Beth Haliburton, Marialena Mouzaki, Monping Chiang, Vikki Scaini, Margaret Marcon, Wenming Duan, David Wilson, Priscilla Pl Chiu, Theo J Moraes
BACKGROUND: Malnutrition is common among congenital diaphragmatic hernia (CDH) survivors and may result from elevated respiratory effort. We evaluated body mass index (BMI), measured resting energy expenditure (mREE) and pulmonary function test (PFT) results in children and adolescents with CDH to determine if there is a correlation. METHODS: With ethics approval (REB# 1000035323), anthropometrics, indirect calorimetry (IC) results and PFTs were collected from patients 5-17years of age during CDH clinic visits between 2000 and 2016...
November 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27910417/new-numerical-simulation-method-to-calibrate-the-regular-hexagonal-nai-tl-detector-with-radioactive-point-sources-situated-non-axial
#11
Ayman Hamzawy, Dimitar N Grozdanov, Mohamed S Badawi, Fuad A Aliyev, Abouzeid A Thabet, Mahmoud I Abbas, Ivan N Ruskov, Ahmed M El-Khatib, Yuri N Kopatch, Mona M Gouda
Scintillation crystals are usually used for detection of energetic photons at room temperature in high energy and nuclear physics research, non-destructive analysis of materials testing, safeguards, nuclear treaty verification, geological exploration, and medical imaging. Therefore, new designs and construction of radioactive beam facilities are coming on-line with these science brunches. A good number of researchers are investigating the efficiency of the γ-ray detectors to improve the models and techniques used in order to deal with the most pressing problems in physics research today...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27906204/design-of-a-large-field-of-view-see-through-near-to-eye-display-with-two-geometrical-waveguides
#12
Jianming Yang, Patrice Twardowski, Philippe Gérard, Joël Fontaine
A novel waveguide near to eye display (WGNED), with new in-coupling and propagation subsystems, is proposed for the first time, to our knowledge, to enlarge the vertical field-of-view (FOV) and the vertical size of the eye box. Two waveguides are stacked-one is for in-coupling and the other for out-coupling. A freeform prism is used to correct the aberrations. These components are combined to form the WGNED. We have simulated such a system; as a result, we show that it achieves a FOV of 30°horizontal (H)×60°vertical (V) and an eye box of about 15  mm (H)×12  mm (V)...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27901227/evaluation-of-cytotoxicity-and-corrosion-resistance-of-orthodontic-mini-implants
#13
Celha Borges Costa Alves, Márcio Nunes Segurado, Miriam Cristina Leandro Dorta, Fátima Ribeiro Dias, Maurício Guilherme Lenza, Marcos Augusto Lenza
Objective: To evaluate and compare in vitro cytotoxicity and corrosion resistance of mini-implants from three different commercial brands used for orthodontic anchorage. Methods: Six mini-implants (Conexão(tm), Neodent(tm) and SIN(tm)) were separately immersed in artificial saliva (pH 6.76) for 30 and 60 days. The cytotoxicity of the corrosion extracts was assessed in L929 cell cultures using the violet crystal and MTT assays, as well as cell morphology under light microscopy...
September 2016: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/27894744/-vitamin-d-deficiency-and-morbimortality-in-critically-ill-paediatric-patients
#14
Patricia García-Soler, Antonio Morales-Martínez, Vanessa Rosa-Camacho, Juan Antonio Lillo-Muñoz, Guillermo Milano-Manso
OBJECTIVES: To determine the prevalence and risks factors of vitamin D deficiency, as well as its relationship with morbidity and mortality in a PICU. MATERIAL AND METHODS: An observational prospective study in a tertiary children's University Hospital PICU conducted in two phases: i: cohorts study, and ii: prevalence study. The study included 340 critically ill children with ages comprising 6 months to 16 years old. EXCLUSION CRITERIA: Chronic kidney disease, known parathyroid disorders, and vitamin D supplementation...
November 25, 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/27893544/visceral-adiposity-genetic-susceptibility-and-risk-of-complications-among-individuals-with-crohn-s-disease
#15
Kimberley W J Van Der Sloot, Amit D Joshi, Danielle R Bellavance, Katherine K Gilpin, Kathleen O Stewart, Paul Lochhead, John J Garber, Cosmas Giallourakis, Vijay Yajnik, Ashwin N Ananthakrishnan, Behrooz Z Alizadeh, Ramnik J Xavier, Hamed Khalili
INTRODUCTION: Adipose tissue in mesenteric fat plays a key role in systemic and luminal inflammation. However, little is known about the role of visceral adipose tissue (VAT) and its interaction with genetic predisposition in Crohn's disease (CD) progression. METHODS: Our study population included patients with CD enrolled in Prospective Registry in Inflammatory Bowel Disease Study at Massachusetts General Hospital (PRISM). VAT volume was measured from computed tomography using Aquarius 3D...
November 22, 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/27892835/effect-of-adhesive-restoration-and-bleaching-technique-on-the-concentration-of-hydrogen-peroxide-in-the-pulp-chamber
#16
V Cavalli, B G Silva, S B Berger, G Abuna, F C Marson, Cpm Tabchoury, M Giannini
This study aimed to quantify the concentration of hydrogen peroxide into the pulp chamber in the presence or absence of adhesive enamel restorations and to analyze the resin-dentin interface of bleached groups. Bovine incisors (120) were randomly divided into three groups according to enamel treatment (n=40 each): (1) enamel without restoration (control); (2) enamel cavities (3 mm diameter × 1.5 mm depth) restored with a silorane-based (SB) system; or (3) enamel cavities (3 mm diameter × 1.5 mm depth) restored with a dimethacrylate-based (DB) system...
November 28, 2016: Operative Dentistry
https://www.readbyqxmd.com/read/27882844/effect-of-glycosylation-on-hydration-behavior-at-the-ice-binding-surface-of-the-oceanpout-type-iii-antifreeze-protein-a-molecular-dynamics-simulation
#17
Swagata Halder, Chaitali Mukhopadhyay
Antifreeze proteins (AFPs), found in certain vertebrates, plants, fungi and bacteria have the ability to permit their survival in subzero environments by thermal hysteresis mechanism. However, the exact mechanism of ice growth inhibition is still not clearly understood. Here four long explicit molecular dynamics (MD) simulations have been carried out at two different temperatures (277K and 298 K)with and without glycan to study the conformational rigidity of the Ocean pout type III antifreeze protein in aqueous medium and the structural arrangements of water molecules hydrating its ice binding surface...
November 24, 2016: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/27881974/the-microbiome-and-occurrence-of-methanotrophy-in-carnivorous-sponges
#18
Jon T Hestetun, Håkon Dahle, Steffen L Jørgensen, Bernt R Olsen, Hans T Rapp
As shown by recent studies, filter-feeding sponges are known to host a wide variety of microorganisms. However, the microbial community of the non-filtering carnivorous sponges (Porifera, Cladorhizidae) has been the subject of less scrutiny. Here, we present the results from a comparative study of the methanotrophic carnivorous sponge Cladorhiza methanophila from a mud volcano-rich area at the Barbados Accretionary Prism, and five carnivorous species from the Jan Mayen Vent Field (JMVF) at the Arctic Mid-Ocean Ridge...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27878249/ets-1-a-potential-target-of-glycolysis-for-metabolic-therapy-by-regulating-glucose-metabolism-in-pancreatic-cancer
#19
Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang
Pancreatic cancer is one of the most lethal malignancies of all types of cancer due to lack of early symptoms and its resistance to conventional therapy. In our previous study, we have shown that v‑ets erythroblastosis virus E26 oncogene homolog‑1 (ETS‑1) promote cell migration and invasion in pancreatic cancer cells. However, the function of ETS‑1 in regulation of glycolysis and autophagy during progression of pancreatic cancer has not been defined yet. In this study, we sought to identify the potential role for silencing ETS‑1 in reducing the expression of glucose transporter‑1 (GLUT‑1) to disturb glycolysis through alteration of 'Warburg effect', by which could result in AMP‑activated protein kinase (AMPK) activation, autophagy induction and reduction of cell viability...
November 16, 2016: International Journal of Oncology
https://www.readbyqxmd.com/read/27874133/the-structural-and-electronic-properties-of-nbsin-0-n-3-12-clusters-anion-photoelectron-spectroscopy-and-ab-initio-calculations
#20
Sheng-Jie Lu, Guo-Jin Cao, Xi-Ling Xu, Hong-Guang Xu, Wei-Jun Zheng
Niobium-doped silicon clusters, NbSin(-) (n = 3-12), were generated by laser vaporization and investigated by anion photoelectron spectroscopy. The structures and electronic properties of NbSin(-) anions and their neutral counterparts were investigated with ab initio calculations and compared with the experimental results. It is found that the Nb atom in NbSin(-/0) prefers to occupy the high coordination sites to form more Nb-Si bonds. The most stable structures of NbSi3-7(-/0) are all exohedral structures with the Nb atom face-capping the Sin frameworks...
December 1, 2016: Nanoscale
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