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Sayantan Deb, Lindsey Voller, Chase Palisch, Omar Ceja, Wes Turner, Homero Rivas, John M Morton
Many payors require an additional attempt at nonsurgical weight loss before approval of bariatric procedures. This study evaluates this requirement by characterizing the prior weight loss attempts (WLAs) undergone by bariatric surgery patients and correlating those attempts to postoperative weight loss outcomes. Number and duration of WLAs were obtained from a preoperative clinic assessment. Body mass index (BMI) and percentage of excess weight loss (%EWL) were used to assess weight loss. Kruskal-Wallis and Spearman Correlation tests were performed to analyze data using GraphPad Prism 6...
October 2016: American Surgeon
Melissa Shields, Swati Sinkar, WengOnn Chan, John Crompton
PURPOSE: To characterize the clinical features, aetiology and management of ophthalmic symptoms in adult patients with Parinaud syndrome. METHODS: This is a retrospective, non-comparative observational case series. We reviewed 40 consecutive charts of adult patients with the clinical diagnosis of Parinaud syndrome at the Royal Adelaide Hospital Department of Ophthalmology in Adelaide, South Australia, between 1991 and 2016. Charts were reviewed for the following: (1) demographic information, (2) clinical presentation, (3) neuro-ophthalmology signs, (4) aetiology of Parinaud syndrome, and (5) management...
October 24, 2016: Acta Ophthalmologica
Ganna Gryn'ova, Michelle L Coote, Clemence Corminboeuf
The electronic configuration of the molecule is the foundation of its structure and reactivity. The spin state is one of the key characteristics arising from the ordering of electrons within the molecule's set of orbitals. Organic molecules that have open-shell ground states and interesting physicochemical properties, particularly those influencing their spin alignment, are of immense interest within the up-and-coming field of molecular electronics. In this advanced review, we scrutinize various qualitative rules of orbital occupation and spin alignment, viz...
November 2015: Wiley Interdisciplinary Reviews. Computational Molecular Science
Pilar S Merino, Rebeca E Vera, Laura G Mariñas, Pilar S Gómez de Liaño, Jose V Escribano
PURPOSE: To study the types of acquired restrictive strabismus treated in a tertiary hospital and the outcome of treatment with botulinum toxin. METHODS: We performed a 10-year retrospective study of patients with restrictive strabismus aged ≥18 years who were treated with botulinum toxin. Treatment was considered successful if the final vertical deviation was ≤5 PD, horizontal deviation ≤10 PD, with no head turn or diplopia. RESULTS: We included 27 cases (mean age, 61...
October 19, 2016: Journal of Optometry
Rupert M Pearse, Tom E Abbott, Richard Haslop, Tahania Ahmad, Brennan C Kahan, Claudia Filipini, Andrew Rhodes, Marco Ranieri
BACKGROUND: Over 300 million patients undergo surgery worldwide each year. Postoperative morbidity - particularly respiratory complications - are most frequent and severe among high-risk patients undergoing major abdominal surgery. However, standard treatments, like physiotherapy or supplemental oxygen, often fail to prevent these. Preliminary research suggests that prophylactic continuous positive airways pressure (CPAP) can reduce the risk of postoperative respiratory complications...
October 20, 2016: Minerva Anestesiologica
Mariya Ptashnyk, Brian Seguin
The microscopic structure and anisotropy of plant cell walls greatly influence the mechanical properties, morphogenesis, and growth of plant cells and tissues. The microscopic structure and properties of cell walls are determined by the orientation and mechanical properties of the cellulose microfibrils and the mechanical properties of the cell wall matrix. Viewing the shape of a plant cell as a square prism with the axis aligning with the primary direction of expansion and growth, the orientation of the microfibrils within the side walls, i...
October 19, 2016: Bulletin of Mathematical Biology
Abolghasem Allahyari, Seyed-Mehdi Hashemi, Fahimeh Nazemian, Mohammad Karimi, Mohammad-Reza Kazemi, Masoud Sadeghi
BACKGROUND: Acute lymphoblastic leukemia (ALL) is aggressive cancer, especially in adults as only 20-40% is cured with current treatment regimens. OBJECTIVES: The aim of this study is to evaluate prognostic factors and their effects on survival in ALL patients in the Northeast of Iran. METHODS: In a descriptive and retrospective study from 2009 to 2015, 48 ALL patients referred to hematology-oncology clinic. Age, sex, fever, blood group, type of ALL and consumption of amphotericin B, forms of cytogenetic, survival in the patients, WBC, hemoglobin, and platelet were checked in the first referral for every patient...
August 2016: Iranian Journal of Cancer Prevention
Rodrigo S Maeda, Shawn M O'Connor, J Maxwell Donelan, Daniel S Marigold
As we walk, we must accurately place our feet to stabilize our motion and to navigate our environment. We must also achieve this accuracy despite imperfect sensory feedback and unexpected disturbances. Here we tested whether the nervous system uses state estimation to beneficially combine sensory feedback with forward model predictions to compensate for these challenges. Specifically, subjects wore prism lenses during a visually guided walking task, and we used trial-by-trial variation in prism lenses to add uncertainty to visual feedback and induce a reweighting of this input...
October 19, 2016: Journal of Neurophysiology
Emil F Khisamutdinov, Daniel L Jasinski, Hui Li, Kaiming Zhang, Wah Chiu, Peixuan Guo
Constructing containers with defined shape and size to load and protect therapeutics and subsequently control their release in the human body has long been a dream. The fabrication of 3D RNA prisms, characterized by atomic force microscopy, cryo-electron microscopy, dynamic light scattering, and polyacrylamide gel electrophoresis, is reported for the loading and protection of small molecules, proteins, small RNA molecules, and their controlled release.
October 19, 2016: Advanced Materials
Narayan Dolai, Aminul Islam, Pallab Kanti Haldar
OBJECTIVE: Anthocephalus cadamba (Roxb.) Miq. (Family: Rubiaceae), a folk medicine commonly known as "Kadam" in Bengali, has been used for the treatment of tumor. The methanolic extract of A. cadamba (MEAC) showing antitumor activity on Ehrlich ascites carcinoma (EAC) cells treated mice was already reported. This study was designed to study the apoptosis-inducing property of MEAC and its mechanism in EAC cells in mice. MATERIALS AND METHODS: Apoptogenic morphology was determined by fluorescent DNA-binding double staining method using dyes acridine orange (AO)/ethidium bromide (EB)...
July 2016: Indian Journal of Pharmacology
Yann-Leei Larry Lee, Kaci D Sims, Charles C Butts, M Amin Frotan, Steven Kahn, Sidney B Brevard, Jon D Simmons
There are few published reports on the unique nature of burn patients using a paired spontaneous awakening and spontaneous breathing protocol. A combined protocol was implemented in our burn intensive care unit (ICU) on January 1, 2012. This study evaluates the impact of this protocol on patient outcomes in a burn ICU. We performed a retrospective review of our burn registry over 4 years, including all patients placed on mechanical ventilation. In the latter 2 years, patients meeting criteria underwent daily spontaneous awakening trial; if successful, spontaneous breathing trial was performed...
October 6, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
Nuria García Marchena, Pedro Araos, Francisco Javier Pavón, Guillermo Ponce, María Pedraz, Antonia Serrano, Francisco Arias, Pablo Romero-Sanchiz, Juan Suárez, Antoni Pastor, Rafael De la Torre, Marta Torrens, Gabriel Rubio, Fernando Rodríguez de Fonseca
Alcohol addiction is associated with high psychiatric comorbidity. Objective stratification of patients is necessary to optimize care and improve prognosis. The present study is designed to gain insights into this challenge by addressing the following objectives: a) to estimate the prevalence of psychiatric comorbidities in a sample of outpatients seeking treatment for alcohol use disorder, b) to describe the existence of gender differences and c) to validate 2-acyl-glycerols as biomarkers of alcohol use disorder and/or psychiatric comorbidity...
September 29, 2016: Adicciones
Yi Chen, Yue Ban, Qi-Biao Zhu, Xi Chen
Graphene-assisted resonant transmission and enhanced Goos-Hänchen shift are investigated in a two-prism frustrated total internal reflection configuration. Due to the excitation of surface plasmons induced by graphene in a low terahertz frequency range, there exist the resonant transmission and anomalous Goos-Hänchen shifts in such an optical tunneling configuration. As compared to the case of the quantum well, a graphene sheet with unique optical properties can enhance the resonant transmission with a relatively low loss and modulate the large negative and positive Goos-Hänchen shifts by adjusting the chemical potential or electron relaxation time...
October 1, 2016: Optics Letters
Michael W Kudenov, Matthew Miskiewicz, Nathan Sanders, Michael J Escuti
We describe a method to achromatize a Wollaston prism beam splitter by combining it with a polarization grating. The advantage of this technique, compared to refractive methods of correction, is that only one type of birefringent crystal is needed. Additionally, the assembly can be made thinner while remaining achromatized. In this Letter, a model for the achromatized grating prism is formulated. Experimental validation is conducted by achromatizing a calcite Wollaston prism (apex angle of 5.35°) using a polarization grating with a spatial period of 253 μm...
October 1, 2016: Optics Letters
Amit Chakraborty, Joydeb Goura, Prasenjit Bag, Arun Kumar Bar, Jean-Pascal Sutter, Vadapalli Chandrasekhar
Utilizing a new ferrocene-based compartmental ligand, H4L (1), a series of novel heterometallic complexes [{LZn(μ-OAc)Dy}4(μ4-H2O)] (2), [{LZn(μ-OAc)Tb}4(μ4-H2O)] (3), [{LZn(μ-OAc)Ho}4(μ4-H2O)] (4), [L = Fe[(C5H4){-C(Me)[double bond, length as m-dash]N-N[double bond, length as m-dash]C6H3-(o-O)(m-O)}]2] were synthesized and characterized. 2 and 3 crystallize in the monoclinic crystal system in the I2/m space group, whereas 4 crystallizes in the tetragonal crystal system in the I4/m space group. The tetra deprotonated ligand L(4-) has two distinct coordination compartments: one pocket (2N, 2O) suitable for the transition metal (3d) ions and another pocket (4O) suitable for lanthanide (4f) metal ions...
October 17, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Ramachandran Rameshkumar, Sriram Krishnamurthy, Rajesh Nachiappa Ganesh, Subramanian Mahadevan, Parameswaran Narayanan, Ponnarmeni Satheesh, Puneet Jain
BACKGROUND: Septic acute kidney injury (AKI) accounts for more than half of all cases of AKI in critically ill children. The renal histology was found to alter the management in more than two-third of cases of adult acute renal failure. Better insight into the pathogenesis of pediatric septic AKI could be based on developing a clearer appreciation of the histopathological changes. No comprehensive study of the histopathological features of septic AKI in critically ill children has yet been performed...
October 13, 2016: Clinical and Experimental Nephrology
Seher Erdoğan, Arzu Oto, Mehmet Boşnak
Mean platelet volume (MPV) is a simple and economical test that is easy to interpret and is routinely measured with automatic cell counters. It indicates platelet volume and platelet function and activation. Variations in platelet volume may occur more as a result of varying differentiation of megakaryocytes in association with production agents in bone marrow rather than of ageing of platelets in circulation. The purpose of this study was to evaluate the relation between mortality and changes in MPV values in patients hospitalized in the pediatric intensive care unit...
November 2015: Turkish Journal of Pediatrics
Pavel Weber, Hana Meluzínová, Dana Prudius, Katarína Bielaková
Polypharmacy is common in the elderly, especially in the late age (over 75 years). Usually it is closely related to the geriatric multi-morbidity. The authors highlight the medication used in the anticipated positive and potential negative potential. While physicians often must make difficult trade-offs between the guidelines on one hand and complicated multi-morbidity, on the other hand, while trying to avoid polypharmacy ( 5 drugs), especially excessive polypharmacy ( 10 drugs). Multimorbid elderly patients who are treated in accordance with guidelines typically use large amounts of medicaments...
2016: Vnitr̆ní Lékar̆ství
K Rajkumar, A Bhattacharya, S David, S Hari Balaji, R Hariharan, M Jayakumar, N Balaji
AIM: This study was conducted to assess the extent of knowledge, awareness, attitude, and risks of zoonotic diseases among livestock owners in Puducherry region. MATERIALS AND METHODS: A total of 250 livestock farmers were selected randomly from eight revenue villages. And each farmer was interviewed with a questionnaire containing both open- and close-ended questions on various aspects of zoonotic diseases, a total of 49 questionnaires were framed to assess the source and transmission of infection to the farmers and to test their knowledge and awareness about zoonotic diseases...
September 2016: Veterinary World
Noelia Morales, Elsa Galbis, Jose M Martinez, Rafael R Pappalardo, Enrique Sanchez Marcos
The angular distribution function (ADF) associated to the oxygen-metal ion-oxygen angle (OMO) of several trivalent lanthanoid and actinoid aquaions has been used to identify the most probable coordination geometry of these aquaions in aqueous solutions. The ADFs extracted from the Molecular Dynamics trajectories have been compared with continuous distribution functions corresponding to the geometry of a reference polyhedron pattern. The procedure incorporates specific quantum-mechanical information of the aquaion under study...
October 12, 2016: Journal of Physical Chemistry Letters
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