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https://www.readbyqxmd.com/read/28730089/an-international-survey-of-classification-and-treatment-choices-for-group-d-retinoblastoma
#1
Christina Scelfo, Jasmine H Francis, Vikas Khetan, Thomas Jenkins, Brian Marr, David H Abramson, Carol L Shields, Jacob Pe'er, Francis Munier, Jesse Berry, J William Harbour, Andrey Yarovoy, Evandro Lucena, Timothy G Murray, Pooja Bhagia, Evelyn Paysse, Samuray Tuncer, Guillermo L Chantada, Annette C Moll, Tatiana Ushakova, David A Plager, Islamov Ziyovuddin, Carlos A Leal, Miguel A Materin, Xun-Da Ji, Jose W Cursino, Rodrigo Polania, Hayyam Kiratli, Charlotta All-Ericsson, Rejin Kebudi, Santosh G Honavar, Vicktoria Vishnevskia-Dai, Sidnel Epelman, Anthony B Daniels, Jeanie D Ling, Fousseyni Traore, Marco A Ramirez-Ortiz
AIM: To determine which IIRC scheme was used by retinoblastoma centers worldwide and the percentage of D eyes treated primarily with enucleation versus globe salvaging therapies as well as to correlate trends in treatment choice to IIRC version used and geographic region. METHODS: An anonymized electronic survey was offered to 115 physicians at 39 retinoblastoma centers worldwide asking about IIRC classification schemes and treatment patterns used between 2008 and 2012...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28729188/assessing-interest-and-barriers-for-resident-and-faculty-involvement-in-global-surgery
#2
Maija Cheung, James M Healy, Michael R Hall, Doruk Ozgediz
BACKGROUND: Multiple institutions have developed international electives and sustainable global surgery initiatives to facilitate clinical, research, and outreach opportunities with hospitals in resource-poor areas. Despite increasing interest among programs, many institutions have not successfully reached potential involvement. OBJECTIVE: This study evaluates the experiences of Yale residents and faculty, measures interest in the development of an international surgical elective, and enumerates barriers to developing or participating in these opportunities...
July 17, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28728290/-advances-in-research-of-divergence-insufficiency
#3
Y P Li, W Zhang
Divergence insufficiency is acquired esotropia at distance fixation with symptomatic uncrossed diplopia but fusion at near. It can be divided into two forms: primary isolated form and secondary form associated with neurologic abnormalities, also called divergence palsy. The clinical features of divergence insufficiency include small esotropia only at distance but orthotropia or small esophoria at near, comitant deviation at lateral gaze, reduced divergence fusion, full abduction and normal saccadic velocities in abduction...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28727615/multiplexing-prisms-for-field-expansion
#4
Eli Peli, Jae-Hyun Jung
PURPOSE: Prisms used for field expansion are limited by the optical scotoma at a prism apex (apical scotoma). For a patient with two functioning eyes, fitting prisms unilaterally allows the other eye to compensate for the apical scotoma. A monocular patient's field loss cannot be expanded with a conventional or Fresnel prism because of the apical scotoma. A newly invented optical device, the multiplexing prism (MxP), was developed to overcome the apical scotoma limitation in monocular field expansion...
July 19, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28726950/one-dna-strand-homo-polymerizes-into-defined-nanostructures
#5
Mo Li, Hua Zuo, Jinwen Yu, Xinfeng Zhao, Chengde Mao
We report a strategy for programmed DNA self-assembly that is favorable in terms of both thermodynamics and kinetics. In a previous study, it has been demonstrated that DNA self-assembly is primarily driven by thermodynamics and the assembly kinetics is not considered. To reach such stable states at equilibria, prolonged annealing duration is needed. In addition, there are cases where the desired structures could not compete with alternative structures. For example, a single-stranded DNA with a palindromic sequence quickly folds into a one-stranded hairpin instead of forming a two-stranded DNA duplex...
July 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28725007/far-and-deep-ultraviolet-surface-plasmon-resonance-sensors-working-in-aqueous-solutions-using-aluminum-thin-films
#6
Ichiro Tanabe, Yoshito Y Tanaka, Koji Watari, Taras Hanulia, Takeyoshi Goto, Wataru Inami, Yoshimasa Kawata, Yukihiro Ozaki
Surface plasmon resonance (SPR) sensors detect refractive index changes on metal thin films and are frequently used in aqueous solutions as bio- and chemical-sensors. Recently, we proposed new SPR sensors using aluminum (Al) thin films that work in the far- and deep-ultraviolet (FUV-DUV, 120-300 nm) regions and investigated SPR properties by an attenuated total reflectance (ATR) based spectrometer. The FUV-DUV-SPR sensors are expected to have three advantages compared to visible-SPR sensors: higher sensitivity, material selectivity, and surface specificity...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724819/stability-and-effects-of-muscle-transplantation-for-very-large-angle-esotropia-a-study-of-22-patients
#7
Jitendra Nenumal Jethani, Nirzari Shah, Sonal Amin, Monika Jethani
PURPOSE: A very large angle esotropia is characterized by an angle more than 80 prism diopters (pd). A single eye surgery would not correct such a large angle. Supramaximal recessions and resection would lead to restriction of ocular motility. We present a series of 22 patients with large angle esotropia treated with muscle transplantation. METHODS: A total of 22 patients (14 males and 8 females) were included in the study. All the patients had a minimum of 80 base out deviation in primary position...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28716536/looking-at-hospitalized-persons-throughout-the-prism-of-the-handicap
#8
M Giral, B Boussat, F Lombard, S Stempfle, P François, D Pérennou
OBJECTIVE: To describe the disability status of non-selected hospitalized persons. METHODS AND FINDINGS: We conducted a cross-sectional survey to assess activity limitations of every person older than 18 years hospitalized in a regional university hospital covering all medical fields. Evaluators rated, on a scale from 0 to 4, 22 selected items of the International Classification of Functioning (ICF), covering the 6 following domains: learning and applying knowledge, general tasks and demands, communication, mobility, self-care, and interpersonal interactions and relationships...
July 14, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28714478/immobilization-of-single-argon-atoms-in-nano-cages-of-two-dimensional-zeolite-model-systems
#9
Jian-Qiang Zhong, Mengen Wang, Nusnin Akter, John D Kestell, Alejandro M Boscoboinik, Taejin Kim, Dario J Stacchiola, Deyu Lu, J Anibal Boscoboinik
The confinement of noble gases on nanostructured surfaces, in contrast to bulk materials, at non-cryogenic temperatures represents a formidable challenge. In this work, individual Ar atoms are trapped at 300 K in nano-cages consisting of (alumino)silicate hexagonal prisms forming a two-dimensional array on a planar surface. The trapping of Ar atoms is detected in situ using synchrotron-based ambient pressure X-ray photoelectron spectroscopy. The atoms remain in the cages upon heating to 400 K. The trapping and release of Ar is studied combining surface science methods and density functional theory calculations...
July 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28713509/mechanical-ventilation-practice-in-egyptian-pediatric-intensive-care-units
#10
Bassant Salah Meligy, Sally Kamal, Seham Awad El Sherbini
INTRODUCTION: Mechanical ventilation is one of the indispensable tools in pediatric intensive care units. Few studies addressed the epidemiology of pediatric patients on mechanical ventilation and the frequently used modes of ventilation. This is the first study to describe the practice of mechanical ventilation (MV) in Egyptian pediatric intensive care units (PICUs). METHODS: This prospective observational study was conducted from January 2014 to December 2014 in two pediatric intensive care units at Cairo University Pediatric Hospital...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28713055/anterior-and-nasal-transposition-of-inferior-oblique-muscle-in-cases-of-superior-oblique-palsy
#11
Rohit Saxena, Medha Sharma, Digvijay Singh, Pradeep Sharma
PURPOSE: To report long-term outcome of inferior oblique anterior and nasal transposition in superior oblique palsy. METHODS: The medical records of patients with superior oblique palsy who underwent inferior oblique anterior nasal transposition were reviewed retrospectively. A comprehensive ophthalmic evaluation, including prism bar cover test and measurement of torsion, was performed for all cases. One-year postoperative results were evaluated for alignment in primary gaze, contralateral gaze, and upgaze; reduction in inferior oblique overaction and changes in fundus torsion to assess long-term outcome of the procedure...
July 13, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28711338/in-vitro-cytocompatibility-of-dental-resin-monomers-on-osteoblast-like-cells
#12
Dominik Kraus, Markus Wolfgarten, Norbert Enkling, Ernst-Heinrich Helfgen, Matthias Frentzen, Rainer Probstmeier, Jochen Winter, Helmut Stark
OBJECTIVES: Dental resin-based materials are widely used in modern dentistry. Especially, resin cements enjoy great popularity and are utilized in many applications. Nevertheless, monomers could be released from the resinous matrix, thus interact with surrounding tissues, cause adverse biological reactions and may lead in cases of implant retained restorations to peri-implant bone destruction. Hence, we performed an in-vitro study to determine cytotoxicity of resin monomers on osteoblast-like cells...
July 12, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28708145/tunable-thz-polariton-laser-based-on-1342%C3%A2-%C3%A2-nm-wavelength-for-enhanced-terahertz-wave-extraction
#13
Andrew J Lee, David J Spence, Helen M Pask
We detail the operation of a THz laser source based on non-linear stimulated polariton scattering (SPS) in Mg:LiNbO<sub>3</sub>. This system utilizes a fundamental wavelength of 1342 nm to completely avoid the negative effect of free-carrier generation within high-resistivity silicon (Si) prisms used to extract THz radiation from the Mg:LiNbO<sub>3</sub> crystal. THz power of up to 23.6 μW (62.3 μW when chopped at 50% duty cycle) was detected at 1.33 THz, and frequency tunability across the range 1...
July 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28707468/prediction-of-novel-high-pressure-structures-of-magnesium-niobium-dihydride
#14
Chuan-Zhao Zhang, Guoliang Sun, Jingjing Wang, Cheng Lu, Yuan-Yuan Jin, Xiaoyu Kuang, Andreas Hermann
Based on a combination of the particle-swarm optimization technique and density functional theory (DFT), we explore the crystal structures of MgH2, NbH2 and MgNbH2 under high pressure. The enthalpy-pressure (H-P) diagrams indicate that the structural transition sequence of MgH2 is α → γ → δ → ε → ζ phase and NbH2 transforms from the Fm-3m phase to the Pnma phase at 47.80 GPa. However, MgNbH2 is unstable when the pressure is too low or too high. Two novel MgNbH2 structures, the hexagonal P-6m2 phase and the orthorhombic Cmcm phase, are discovered, which are stable in the pressure ranges of 13...
July 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28706331/bioequivalence-of-generic-and-branded-amoxicillin-capsules-in-healthy-human-volunteers
#15
Priyanka Pathak, Vijaya A Pandit, Priti P Dhande
CONTEXT: The Medical Council of India urges doctors to prescribe generic drugs as far as possible. The Indian Medical Association had responded earlier saying that it requires guarantees on the quality of generic forms of drugs. Although no published scientific reports are available on the issue of therapeutic inequivalence, unconfirmed clinician accounts and newspaper reports of therapeutic inequivalence exist. AIM: This study was planned to ascertain whether bioequivalence of branded and generic amoxicillin capsule is comparable...
March 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28705429/disinfection-of-tonometers-a-report-by-the-american-academy-of-ophthalmology
#16
Anna K Junk, Philip P Chen, Shan C Lin, Kouros Nouri-Mahdavi, Sunita Radhakrishnan, Kuldev Singh, Teresa C Chen
OBJECTIVE: To examine the efficacy of various disinfection methods for reusable tonometer prisms in eye care and to highlight how disinfectants can damage tonometer tips and cause subsequent patient harm. METHODS: Literature searches were conducted last in October 2016 in the PubMed and the Cochrane Library databases for original research investigations. Reviews, non-English language articles, nonophthalmology articles, surveys, and case reports were excluded. RESULTS: The searches initially yielded 64 unique citations...
July 11, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28702528/stability-and-growth-mechanism-of-self-assembling-putative-antifreeze-cyclic-peptides
#17
Z Faidon Brotzakis, Mascha Gehre, Ilja K Voets, Peter G Bolhuis
Cyclic peptides (CPs) that self-assemble in nanotubes can be candidates for use as antifreeze proteins. Based on the cyclic peptide sequence cyclo-[(l-LYS-d-ALA-l-LEU-d-ALA)2], which can stack into nanotubes, we propose a putative antifreeze cyclic peptide (AFCP) sequence, cyclo-[(l-LYS-d-ALA)2-(l-THR-d-ALA)2], containing THR-ALA-THR ice binding motifs. Using molecular dynamics simulations we investigate the stability of these cyclic peptides and their growth mechanism. Both nanotube sequences get more stable as a function of size...
July 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28697652/ask-the-experts-how-to-treat-individuals-with-spatial-neglect-a-survey-study
#18
Peii Chen, Marco Pitteri, Glen Gillen, Harsha Ayyala
PURPOSE: Spatial neglect (SN) impedes rehabilitation success and leaves long-term consequences. We asked experts to provide their opinions in addressing SN by scenario (ideal vs. reality) and by recovery phase (earliest, acute, subacute, and chronic). Experts were individuals who have assessed or treated patients with SN clinically. MATERIALS AND METHODS: This study was conducted using an anonymous survey on the Internet with 189 responders over 3 months. Located in 23 different countries, 127 experts of seven disciplines were included (occupational therapy, physical therapy, nursing, speech and language pathology or therapy, neurology, physical medicine and rehabilitation, and psychology or neuropsychology)...
July 11, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28696880/performance-of-pediatric-risk-of-mortality-score-among-critically-ill-children-with-heart-disease
#19
Rebecca A Russell, Mallikarjuna Rettiganti, Nancy Brundage, Howard E Jeffries, Punkaj Gupta
OBJECTIVE: To evaluate the performance of the Pediatric Risk of Mortality 3 (PRISM-3) score in critically ill children with heart disease. METHODS: Patients <18 years of age admitted with cardiac diagnoses (cardiac medical and cardiac surgical) to one of the participating pediatric intensive care units in the Virtual Pediatric Systems, LLC, database were included. Performance of PRISM-3 was evaluated with discrimination and calibration measures among both cardiac surgical and cardiac medical patients...
July 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28696298/functional-characterization-of-odorant-receptors-in-the-ponerine-ant-harpegnathos-saltator
#20
Jesse D Slone, Gregory M Pask, Stephen T Ferguson, Jocelyn G Millar, Shelley L Berger, Danny Reinberg, Jürgen Liebig, Anandasankar Ray, Laurence J Zwiebel
Animals use a variety of sensory modalities-including visual, acoustic, and chemical-to sense their environment and interact with both conspecifics and other species. Such communication is especially critical in eusocial insects such as honey bees and ants, where cooperation is critical for survival and reproductive success. Various classes of chemoreceptors have been hypothesized to play essential roles in the origin and evolution of eusociality in ants, through their functional roles in pheromone detection that characterizes reproductive status and colony membership...
July 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
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