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https://www.readbyqxmd.com/read/27837451/percutaneous-image-guided-cryoablation-current-applications-and-results-in-the-oncologic-field
#1
Roberto Luigi Cazzato, Julien Garnon, Nitin Ramamurthy, Guillaume Koch, Georgia Tsoumakidou, Jean Caudrelier, Francesco Arrigoni, Luigi Zugaro, Antonio Barile, Carlo Masciocchi, Afshin Gangi
Percutaneous imaging-guided cryoablation (PICA) is a recently developed technique, which applies extreme hypothermia to destroy tumours under close imaging surveillance. It is minimally invasive, safe, repeatable, and does not interrupt or compromise other oncologic therapies. It presents several advantages over more established heat-based thermal ablation techniques (e.g. radiofrequency ablation; RFA) including intrinsic analgesic properties, superior monitoring capability on multi-modal imaging, ability to treat larger tumours, and preservation of tissue collagenous architecture...
December 2016: Medical Oncology
https://www.readbyqxmd.com/read/27770469/toward-imaging-the-body-at-10-5-tesla
#2
M Arcan Ertürk, Xiaoping Wu, Yiğitcan Eryaman, Pierre-François Van de Moortele, Edward J Auerbach, Russell L Lagore, Lance DelaBarre, J Thomas Vaughan, Kâmil Uğurbil, Gregor Adriany, Gregory J Metzger
PURPOSE: To explore the potential of performing body imaging at 10.5 Tesla (T) compared with 7.0T through evaluating the transmit/receive performance of similarly configured dipole antenna arrays. METHODS: Fractionated dipole antenna elements for 10.5T body imaging were designed and evaluated using numerical simulations. Transmit performance of antenna arrays inside the prostate, kidneys and heart were investigated and compared with those at 7.0T using both phase-only radiofrequency (RF) shimming and multi-spoke pulses...
October 21, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27670618/an-update-on-focal-therapy-for-prostate-cancer
#3
REVIEW
Marlon Perera, Nishanth Krishnananthan, Uri Lindner, Nathan Lawrentschuk
Globally, the increased uptake of serum PSA level screening led to an increase in the number of diagnoses of low-risk and intermediate-risk prostate cancer. Traditionally, these patients have been considered for either active surveillance programmes or radical whole-gland therapies, such as prostatectomy or radiotherapy. Focal therapy is an emerging treatment option that involves the focal ablation of prostate cancer with preservation of surrounding healthy tissue. This approach might result in reduced morbidity when compared with whole-gland therapies...
November 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27595377/new-and-established-technology-in-focal-ablation-of-the-prostate-a-systematic-review
#4
Massimo Valerio, Yannick Cerantola, Scott E Eggener, Herbert Lepor, Thomas J Polascik, Arnauld Villers, Mark Emberton
CONTEXT: Focal therapy of prostate cancer has been proposed as an alternative to whole-gland treatments. OBJECTIVE: To summarize the evidence regarding sources of energy employed in focal therapy. EVIDENCE ACQUISITION: Embase and Medline (PubMed) were searched from 1996 to October 31, 2015 following the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. Ongoing trials were selected from electronic registries. The stage of assessment of each source of energy was determined using the Idea, Development, Exploration, Assessment, Long-term study recommendations...
August 29, 2016: European Urology
https://www.readbyqxmd.com/read/27573795/evaluation-of-frequency-domain-analysis-of-a-multiwavelength-photoacoustic-signal-for-differentiating-malignant-from-benign-and-normal-prostates-ex-vivo-study-with-human-prostates
#5
Saugata Sinha, Navalgund A Rao, Bhargava K Chinni, Vikram S Dogra
OBJECTIVES: The purpose of this study was to investigate the feasibility of differentiating malignant prostate from benign prostatic hyperplasia (BPH) and normal prostate tissue by performing frequency domain analysis of photoacoustic images acquired at 2 different wavelengths. METHODS: We performed multiwavelength photoacoustic imaging on freshly excised human prostate specimens taken from a total of 30 patients undergoing prostatectomy for biopsy-confirmed prostate cancer...
October 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27504133/development-of-a-magnetic-resonance-imaging-protocol-to-visualize-encapsulated-contrast-agent-markers-in-prostate-brachytherapy-recipients-initial-patient-experience
#6
Tze Yee Lim, Rajat J Kudchadker, Jihong Wang, Tharakeswara Bathala, Janio Szklaruk, Thomas J Pugh, Usama Mahmood, Geoffrey S Ibbott, Steven J Frank
PURPOSE: Computed tomography (CT)-based prostate post-implant dosimetry allows for definitive seed localization but is associated with high interobserver variation in prostate contouring. Currently, magnetic resonance imaging (MRI)-based post-implant dosimetry allows for accurate anatomical delineation but is limited due to inconsistent seed localization. Encapsulated contrast agent markers were previously proposed to overcome the seed localization limitation on MRI images by placing hyperintense markers adjacent to hypointense seeds...
June 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27370146/effect-of-pulse-sequence-parameter-selection-on-signal-strength-in-positive-contrast-mri-markers-for-mri-based-prostate-postimplant-assessment
#7
Tze Yee Lim, Rajat J Kudchadker, Jihong Wang, R Jason Stafford, Christopher MacLellan, Arvind Rao, Geoffrey S Ibbott, Steven J Frank
PURPOSE: For postimplant dosimetric assessment, computed tomography (CT) is commonly used to identify prostate brachytherapy seeds, at the expense of accurate anatomical contouring. Magnetic resonance imaging (MRI) is superior to CT for anatomical delineation, but identification of the negative-contrast seeds is challenging. Positive-contrast MRI markers were proposed to replace spacers to assist seed localization on MRI images. Visualization of these markers under varying scan parameters was investigated...
July 2016: Medical Physics
https://www.readbyqxmd.com/read/26962198/clinical-applications-of-stereotactic-radiation-therapy-for-oligometastatic-cancer-patients-a-disease-oriented-approach
#8
Umberto Ricardi, Serena Badellino, Andrea Riccardo Filippi
Oligometastases from solid tumors are currently recognized as a distinct clinical entity, corresponding to an intermediate state between local and widespread disease. It has been suggested that local ablative therapies (including surgery, radiofrequency ablation and radiation therapy) play an important role in this setting, in combination or not with systemic therapies, particularly in delaying disease progression and hopefully in increasing the median survival time. Stereotactic body radiation therapy (SBRT) rapidly emerged in recent years as one of the most effective and less toxic local treatment modalities for lung, liver, adrenal, brain and bone metastases...
March 8, 2016: Journal of Radiation Research
https://www.readbyqxmd.com/read/26893857/evaluation-of-in-vivo-efficacy-of-radiofrequency-ablation-with-d-sorbitol-in-animal-liver
#9
Asahiro Morishita, Teppei Sakamoto, Hideki Kobara, Tomoko Tadokoro, Kyoko Ohura, Koji Fujita, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Tsutomu Masaki
Percutaneous radiofrequency ablation (RFA) enables cauterization of liver cancer in a limited number of sessions without major complications. In contrast to the efficacy of this technique, the size of coagulation necrosis is limited due to increased impedance. D-sorbitol has been used as an irrigating fluid during transurethral resection of the prostate, since it is considered to be a dielectric fluid. In order to determine whether D-sorbitol enhances the effect of RFA, RFA was performed by slowly injecting 3% D-sorbitol near the tip of the RFA needle...
February 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/26887533/a-16-channel-combined-loop-dipole-transceiver-array-for-7-tesla-body-mri
#10
M Arcan Ertürk, Alexander J E Raaijmakers, Gregor Adriany, Kâmil Uğurbil, Gregory J Metzger
PURPOSE: To develop a 16-channel transceive body imaging array at 7.0 T with improved transmit, receive, and specific absorption rate (SAR) performance by combining both loop and dipole elements and using their respective and complementary near and far field characteristics. METHODS: A 16-channel radiofrequency (RF) coil array consisting of eight loop-dipole blocks (16LD) was designed and constructed. Transmit and receive performance was quantitatively investigated in phantom and human model simulations, and experiments on five healthy volunteers inside the prostate...
February 17, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/26719802/non-invasive-magnetic-resonance-guided-high-intensity-focused-ultrasound-ablation-of-a-vascular-malformation-in-the-lower-extremity-a-case-report
#11
Johanna M M van Breugel, Robbert J Nijenhuis, Mario G Ries, Raechel J Toorop, Evert-Jan P A Vonken, Joost W Wijlemans, Maurice A A J van den Bosch
INTRODUCTION: Therapy of choice for symptomatic vascular malformations consists of surgery, sclerotherapy, or embolization. However, these techniques are invasive with possible complications and require hospitalization. We present a novel non-invasive technique, i.e., magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablation, for the treatment of a vascular malformation in a patient. This technique applies high-intensity sound waves transcutaneously to the body and is fully non-invasive...
2015: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/26638594/radiofrequency-ablation-of-lung-metastasis-not-suitable-for-surgery-experience-in-siriraj-hospital
#12
Trongtum Tongdee, Pattama Tantigate, Ranista Tongdee
BACKGROUND: Percutaneous image-guided radiofrequency ablation (RFA) is being promoted as a novel technique with low morbidity rate in treatment of inoperable lung tumor either primary lung tumor or metastatic disease. OBJECTIVE: To report our experiences of RFA treated for lung metastasis in Siriraj Hospital and to evaluate the efficacy and complication of RFA. MATERIAL AND METHOD: All patients who underwent RFA for lung metastasis at Siriraj Hospital, between January 2007 and December 2013, were included in the present study...
October 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/26458324/low-frequency-and-low-intensity-ultrasound-mediated-microvessel-disruption-enhance-the-effects-of-radiofrequency-ablation-on-prostate-cancer-xenografts-in-nude-mice
#13
Yu Yang, Wenkun Bai, Yini Chen, Wei Zhang, Meiwen Wang, Bing Hu
The aim of the present study was to examine the impact of low-frequency, low-intensity ultrasound (US)-stimulated microbubbles (USMB) on radiofrequency ablation (RFA) in the treatment of nude mice with human prostate cancer xenografts. The tumor‑bearing nude mice were divided into three groups: The USMB+RFA group was treated with USMB immediately followed by RFA, the RFA group was treated with RFA alone, and the control group remained untreated. The animals underwent enhanced US to calculate the tumor volumes, ablation volumes and ablation rates...
November 2015: Molecular Medicine Reports
https://www.readbyqxmd.com/read/26317083/minimally-invasive-devices-for-treating-lower-urinary-tract-symptoms-in-benign-prostate-hyperplasia-technology-update
#14
REVIEW
Fouad Aoun, Quentin Marcelis, Thierry Roumeguère
Benign prostatic hyperplasia (BPH) represents a spectrum of related lower urinary tract symptoms (LUTS). The cost of currently recommended medications and the discontinuation rate due to side effects are significant drawbacks limiting their long-term use in clinical practice. Interventional procedures, considered as the definitive treatment for BPH, carry a significant risk of treatment-related complications in frail patients. These issues have contributed to the emergence of new approaches as alternative options to standard therapies...
2015: Research and Reports in Urology
https://www.readbyqxmd.com/read/26300045/small-field-of-view-single-shot-epi-dwi-of-the-prostate-evaluation-of-spatially-tailored-two-dimensional-radiofrequency-excitation-pulses
#15
Ulrike I Attenberger, Nils Rathmann, Metin Sertdemir, Philipp Riffel, Anja Weidner, Stefan Kannengiesser, John N Morelli, Stefan O Schoenberg, Daniel Hausmann
PURPOSE: Spatially-tailored (RF) excitation pulses in echo-planar imaging (EPI), combined with a decreased FOV in the phase-encoding direction, enable a reduction of k-space acquisition lines, which shortens the echo train length (ETL) and reduces susceptibility artifacts. The purpose of this study was to evaluate the image quality of a zoomed EPI (z-EPI) sequence in diffusion-weighted imaging (DWI) of the prostate in comparison to a conventional single-shot EPI using single-channel (c-EPI1) and multi-channel (c-EPI2) RF excitation, with and without use of an endorectal coil...
June 2016: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/26069205/effect-of-parallel-radiofrequency-transmission-on-arterial-input-function-selection-in-dynamic-contrast-enhanced-3-tesla-pelvic-mri
#16
Hatim Chafi, Saba N Elias, Huyen T Nguyen, Harry T Friel, Michael V Knopp, BeiBei Guo, Steven B Heymsfield, Guang Jia
BACKGROUND: To evaluate whether parallel radiofrequency transmission (mTX) can improve the symmetry of the left and right femoral arteries in dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of prostate and bladder cancer. METHODS: Eighteen prostate and 24 bladder cancer patients underwent 3.0 Tesla DCE-MRI scan with a single transmission channel coil. Subsequently, 21 prostate and 21 bladder cancer patients were scanned using the dual channel mTX upgrade...
January 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/25988937/modern-palliative-treatments-for-metastatic-bone-disease-awareness-of-advantages-disadvantages-and-guidance
#17
Andreas F Mavrogenis, Andrea Angelini, Christos Vottis, Elisa Pala, Teresa Calabrò, Panayiotis J Papagelopoulos, Pietro Ruggieri
BACKGROUND: Metastatic disease is the most common malignancy of the bone. Prostate, breast, lung, kidney, and thyroid cancer account for 80% of skeletal metastases. Bone metastases are associated with significant skeletal morbidity including severe bone pain, pathologic fractures, spinal cord or nerve roots compression, and malignant hypercalcemia. These events compromise greatly the quality of life of the patients. The treatment of cancer patients with bone metastases is mostly aimed at palliation...
April 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/25974203/multiparametric-magnetic-resonance-imaging-in-prostate-cancer-management-current-status-and-future-perspectives
#18
REVIEW
Tom W J Scheenen, Andrew B Rosenkrantz, Masoom A Haider, Jurgen J Fütterer
This article reviews recent and ongoing developments in multiparametric magnetic resonance imaging (mpMRI) of the prostate. Advances in T2-weighted imaging, diffusion-weighted imaging, dynamic contrast-enhanced imaging, and spectroscopic imaging are described along with advances related to radiofrequency coils and imaging at high magnetic field. As mpMRI is increasingly becoming routine in various aspects of clinical prostate cancer management, its role in detection, localization, staging, assessment of aggressiveness, and active surveillance is discussed...
September 2015: Investigative Radiology
https://www.readbyqxmd.com/read/25955712/review-of-temperature-dependence-of-thermal-properties-dielectric-properties-and-perfusion-of-biological-tissues-at-hyperthermic-and-ablation-temperatures
#19
REVIEW
Christian Rossmanna, Dieter Haemmerich
The application of supraphysiological temperatures (>40°C) to biological tissues causes changes at the molecular, cellular, and structural level, with corresponding changes in tissue function and in thermal, mechanical and dielectric tissue properties. This is particularly relevant for image-guided thermal treatments (e.g. hyperthermia and thermal ablation) delivering heat via focused ultrasound (FUS), radiofrequency (RF), microwave (MW), or laser energy; temperature induced changes in tissue properties are of relevance in relation to predicting tissue temperature profile, monitoring during treatment, and evaluation of treatment results...
2014: Critical Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/25841740/the-role-of-cryosurgery-in-palliative-care-for-cancer
#20
Lizhi Niu, Liang Zhou, Kecheng Xu, Feng Mu
Cryosurgery as one of the ablation methods is performed intraoperatively, laparoscopically or percutaneously, is especially adapted for ablation of prostate cancer, liver cancer, lung cancer, kidney cancer, breast cancer, benign fibroadenomas of breast, uterine tumors and neoplasms of soft tissue. Compared with other ablation methods (such as radiofrequency and microwave ablation), cryoablation has several advantages on therapeutic efficacy, imaging guidance and modality.
January 2013: Annals of Palliative Medicine
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