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https://www.readbyqxmd.com/read/29662231/processed-meat-and-risk-of-selected-digestive-tract-and-laryngeal-cancers
#1
Valentina Rosato, Daisuke Kawakita, Eva Negri, Diego Serraino, Werner Garavello, Maurizio Montella, Adriano Decarli, Carlo La Vecchia, Monica Ferraroni
BACKGROUND/OBJECTIVES: To assess the association between processed meat and the risk of selected digestive tract and laryngeal cancers. SUBJECTS/METHODS: We conducted a series of case-control studies between 1985 and 2007 in Italy. The studies included a total of 1475 cases of cancer of the oral cavity and pharynx, 1077 of the larynx, 716 of the esophagus, 999 of the stomach, 684 of the liver, 159 of the biliary tract, 688 of the pancreas, and a total of 9720 controls...
April 16, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29662019/liposomal-drug-delivery-systems-and-anticancer-drugs
#2
REVIEW
Temidayo O B Olusanya, Rita Rushdi Haj Ahmad, Daniel M Ibegbu, James R Smith, Amal Ali Elkordy
Cancer is a life-threatening disease contributing to ~3.4 million deaths worldwide. There are various causes of cancer, such as smoking, being overweight or obese, intake of processed meat, radiation, family history, stress, environmental factors, and chance. The first-line treatment of cancer is the surgical removal of solid tumours, radiation therapy, and chemotherapy. The systemic administration of the free drug is considered to be the main clinical failure of chemotherapy in cancer treatment, as limited drug concentration reaches the tumour site...
April 14, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29616242/dietary-impact-on-esophageal-cancer-in-humans-a-review
#3
REVIEW
Rachna Khosla Sardana, Navnidhi Chhikara, Beenu Tanwar, Anil Panghal
Cancer is the abnormal growth of cells that tend to proliferate in an uncontrolled way. About 32.6 million people in the world are affected by different types of cancer; 456 000 have esophageal cancer, which is the eighth most common cancer and the sixth most common cause of cancer-related deaths with a toll of 400 000 in 2012. About 80% of cases were reported from the less developed regions of the world. An incidence ratio of 2.4 : 1 for men and women reveals the gender disparity. Esophageal cancer is mainly of two types, namely, squamous cell carcinoma and adenocarcinoma...
April 4, 2018: Food & Function
https://www.readbyqxmd.com/read/29606182/review-dairy-foods-red-meat-and-processed-meat-in-the-diet-implications-for-health-at-key-life-stages
#4
D I Givens
Social and health care provision have led to substantial increases in life expectancy. In the UK this has become higher than 80 years with an even greater proportional increase in those aged 85 years and over. The different life stages give rise to important nutritional challenges and recent reductions in milk consumption have led to sub-optimal intakes of calcium by teenage females in particular when bone growth is at its maximum and of iodine during pregnancy needed to ensure that supply/production of thyroid hormones to the foetus is adequate...
April 2, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29596660/metabolic-activation-of-the-cooked-meat-carcinogen-2-amino-1-methyl-6-phenylimidazo-4-5-b-pyridine-in-human-prostate
#5
Medjda Bellamri, Shun Xiao, Paari Murugan, Christopher J Weight, Robert J Turesky
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), an heterocyclic aromatic amine (HAA) formed in cooked meat, is a rodent and possible human prostate carcinogen. Recently, we identified DNA adducts of PhIP in the genome of prostate cancer patients, but adducts of 2-amino-3,8-dimethylmidazo[4,5-f]quinoxaline (MeIQx) and 2-amino-9H-pyrido[2,3-b]indole (AαC), other prominent HAAs formed in cooked meats, were not detected. We have investigated the bioactivation of HAAs by Phase I and II enzymes in the human prostate (LNCaP) cell line using cytotoxicity and DNA adducts as endpoints...
March 27, 2018: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29589125/cadmium-in-the-shore-crab-carcinus-maenas-along-the-norwegian-coast-geographical-and-seasonal-variation-and-correlation-to-physiological-parameters
#6
Heidi Knutsen, Martin Wiech, Arne Duinker, Amund Maage
Previously, high concentrations of cadmium have been found in the hepatopancreas of the edible or brown crab (Cancer pagurus) sampled from positions north of about 67° N, compared to regions further south along the Norwegian coast, with no clear understanding why. In order to study a similar organism in the same ecosystem, the present study analyzed 210 shore crabs (Carcinus maenas) from four different locations along the Norwegian coast, two in the North and two in the South. The physiological variables size, sex, molting stage, hepatosomatic index, carapace color, and gonad maturation were registered, in attempt to explain the high inter-individual variation in cadmium levels in hepatopancreas...
March 27, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29582162/low-adherence-to-the-western-and-high-adherence-to-the-mediterranean-dietary-patterns-could-prevent-colorectal-cancer
#7
Adela Castelló, Pilar Amiano, Nerea Fernández de Larrea, Vicente Martín, Maria Henar Alonso, Gemma Castaño-Vinyals, Beatriz Pérez-Gómez, Rocío Olmedo-Requena, Marcela Guevara, Guillermo Fernandez-Tardon, Trinidad Dierssen-Sotos, Cristobal Llorens-Ivorra, Jose María Huerta, Rocío Capelo, Tania Fernández-Villa, Anna Díez-Villanueva, Carmen Urtiaga, Jesús Castilla, Jose Juan Jiménez-Moleón, Víctor Moreno, Verónica Dávila-Batista, Manolis Kogevinas, Nuria Aragonés, Marina Pollán
PURPOSE: To assess if the associations found between three previously identified dietary patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC). METHODS: MCC-Spain is a multicase-control study that collected information of 1629 incident cases of CRC and 3509 population-based controls from 11 Spanish provinces. Western, Prudent and Mediterranean data-driven dietary patterns-derived in another Spanish case-control study-were reconstructed in MCC-Spain...
March 26, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29579789/risk-factors-for-cholangiocarcinoma-in-thailand-a-systematic-review-and-meta-analysis
#8
REVIEW
Siriporn Kamsa-ard, Supot Kamsa-ard, Vor Luvira, Krittika Suwanrungruang, Patravoot Vatanasapt, Surapon Wiangnon
Background and objective: Cholangiocarcinoma remains a serious public health concern in Thailand. While many of the risk factors for cholangiocarcinoma in western countries are well-recognized, it remains unclear whether they are the same in Thailand. We set out to investigate the risk factors for cholangiocarcinoma in Thailand. Methods: Starting March 4, 2016, we reviewed studies found using pre-specified keywords on SCOPUS, Pro Quest Science Direct, PubMed, and online public access catalog of Khon Kaen University...
March 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29574860/a-dietary-pattern-based-on-estrogen-metabolism-is-associated-with-breast-cancer-risk-in-a-prospective-cohort-of-postmenopausal-women
#9
Mark A Guinter, Alexander C McLain, Anwar T Merchant, Dale P Sandler, Susan E Steck
Increased exposure to estrogen is a risk factor for postmenopausal breast cancer, and dietary factors can influence estrogen metabolism. However, studies of diet and breast cancer have been inconclusive. We developed a dietary pattern associated with levels of unconjugated estradiol and the ratio of 2- and 16-hydroxylated estrogen metabolites in a subsample of Prostate, Lung, Colorectal and Ovarian Screening Trial (PLCO) participants (n=653) using reduced rank regression, and examined its association with postmenopausal breast cancer prospectively in the larger PLCO cohort (n=27,488)...
March 25, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29571606/processed-meat-and-selected-hormone-related-cancers
#10
Valentina Rosato, Eva Negri, Fabio Parazzini, Diego Serraino, Maurizio Montella, Monica Ferraroni, Adriano Decarli, Carlo La Vecchia
OBJECTIVE: To assess and quantify the association between processed meat consumption and cancers of the breast, endometrium, ovary, and prostate. METHODS: Data were derived from an integrated network of hospital-based case-control studies conducted between 1982 and 2006 in various Italian areas. These studies included 5981 cases of cancer of the breast, 992 of the endometrium, 2002 of the ovary, 1582 of the prostate, and a total of 16 394 controls with data on processed meat...
May 2018: Nutrition
https://www.readbyqxmd.com/read/29570985/processed-meat-and-risk-of-renal-cell-and-bladder-cancers
#11
Valentina Rosato, Eva Negri, Diego Serraino, Maurizio Montella, Massimo Libra, Pagona Lagiou, Gaetano Facchini, Monica Ferraroni, Adriano Decarli, Carlo La Vecchia
We assessed the association of processed meat intake with the risk of renal cell carcinoma (RCC) and bladder cancer. We used data from two Italian hospital-based case-control studies, including 1,115 RCC cases and 2,582 controls, and 1,417 bladder cancer cases and 1,732 controls. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) with unconditional logistic regression models, adjusted for major confounders. The median consumption of processed meat in cases and controls was around 2 portions/week (50 g/portion)...
March 23, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29566186/meat-and-fiber-intake-and-interaction-with-pattern-recognition-receptors-tlr1-tlr2-tlr4-and-tlr10-in-relation-to-colorectal-cancer-in-a-danish-prospective-case-cohort-study
#12
Tine Iskov Kopp, Ulla Vogel, Anne Tjonneland, Vibeke Andersen
Background: Meat and dietary fiber are associated with increased and decreased risk of colorectal cancer (CRC), respectively. Toll-like receptors (TLRs) regulate the intestinal immune response in a complex interplay between the mucosal epithelium and the microbiota and may therefore be important modulators of diet-induced CRC together with other inflammatory mediators. Objective: Our aim was to investigate the association between functional TLR polymorphisms and risk of CRC and the interaction with dietary factors...
March 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29565803/meat-consumption-and-risk-of-metabolic-syndrome-results-from-the-korean-population-and-a-meta-analysis-of-observational-studies
#13
Youngyo Kim, Youjin Je
Many studies have reported harmful effects of red meat or processed meat on chronic diseases including cancer and diabetes, but epidemiological evidence for metabolic syndrome is limited and remains controversial. Therefore, we performed a meta-analysis of observational studies to assess the association between various meat consumption and risk of metabolic syndrome. The PubMed and ISI Web of Science databases were searched through June 2017, and further included unpublished results from Korea National Health and Nutrition Examination Survey 2012-2015, including 8387 Korean adults...
March 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29563037/meat-intake-methods-and-degrees-of-cooking-and-breast-cancer-risk-in-the-mcc-spain-study
#14
Elena Boldo, Adela Castelló, Nuria Aragonés, Pilar Amiano, Beatriz Pérez-Gómez, Gemma Castaño-Vinyals, Vicente Martín, Marcela Guevara, Carmen Urtiaga, Trinidad Dierssen-Sotos, Guillermo Fernández-Tardón, Victor Moreno, Marta Solans, Rosanna Peiró, Rocio Capelo, Inés Gómez-Acebo, Jesús Castilla, Antonio José Molina, Xavier Castells, Jone M Altzibar, Virginia Lope, Manolis Kogevinas, Isabelle Romieu, Marina Pollán
OBJECTIVE: To analyse the relationship of the risk of breast cancer (BC) to meat intake, preference regarding degree of cooking ('doneness') and cooking methods, using data from a population-based case-control study (MCC-Spain). STUDY DESIGN: 1006 Histologically confirmed incident BC cases and 1370 controls were recruited in 10 Spanish provinces. Participants were 23-85 years old. They answered an epidemiological survey and a food frequency questionnaire. BC risk was assessed overall, by menopausal status and by pathological subtypes, using logistic and multinomial regression mixed models adjusted for known confounding factors and including province as a random effects term...
April 2018: Maturitas
https://www.readbyqxmd.com/read/29559669/investigation-of-dietary-factors-and-esophageal-cancer-knowledge-comparison-of-rural-residents-in-high-and-low-incidence-areas
#15
Dong Tian, Shuai-Jia Mo, Lian-Kui Han, Liang Cheng, Heng Huang, Shuai Hao, Ye-Lan Guan, Kai-Yuan Jiang, Jing-Ya Deng, Hu-Hao Feng, Hong-Ying Wen, Mao-Yong Fu
To compare the differences in dietary status and knowledge of esophageal cancer (EC) between residents of high- and low-incidence areas. We investigated dietary conditions and EC knowledge among residents in high- and low-EC incidence areas (Yanting and Qingzhen counties). Residents in Yanting consumed more pickled vegetables, salted meat and barbecued food (P < 0.05). Analysis of the past ten-year trend in Yanting consumed fresh vegetables/fruits, beans, sauerkraut, hot food, and barbecued food had gradually increased, and the trend was less than that in Qingzhen County...
March 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29549740/development-and-validation-of-an-ultra-high-performance-liquid-chromatography-electrospray-tandem-mass-spectrometry-method-using-selective-derivatisation-for-the-quantification-of-two-reactive-aldehydes-produced-by-lipid-peroxidation-hne-4-hydroxy-2-e-nonenal
#16
S Chevolleau, M-H Noguer-Meireles, I Jouanin, N Naud, F Pierre, F Gueraud, L Debrauwer
Red or processed meat rich diets have been shown to be associated with an elevated risk of colorectal cancer (CRC). One major hypothesis involves dietary heme iron which induces lipid peroxidation. The quantification of the resulting reactive aldehydes (e.g. HNE and HHE) in the colon lumen is therefore of great concern since these compounds are known for their cytotoxic and genotoxic properties. UHPLC-ESI-MS/MS method has been developed and validated for HNE and HHE quantification in rat faeces. Samples were derivatised using a brominated reagent (BBHA) in presence of pre-synthesized deuterated internal standards (HNE-d11/HHE-d5), extracted by solid phase extraction, and then analysed by LC-positive ESI-MS/MS (MRM) on a TSQ Vantage mass spectrometer...
March 2, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29545734/relative-validity-of-a-short-food-frequency-questionnaire-assessing-adherence-to-the-norwegian-dietary-guidelines-among-colorectal-cancer-patients
#17
Hege Berg Henriksen, Monica Hauger Carlsen, Ingvild Paur, Sveinung Berntsen, Siv Kjølsrud Bøhn, Anne Juul Skjetne, Ane Sørlie Kværner, Christine Henriksen, Lene Frost Andersen, Sigbjørn Smeland, Rune Blomhoff
Background: The Norwegian food-based dietary guidelines (FBDG) aim at reducing the risk of developing chronic diseases and promote overall health. We studied the effect of the Norwegian FBDG in colorectal cancer (CRC) patients. There is a need for a time-efficient dietary assessment tool measuring adherence to these guidelines in patients treated for dietary dependent cancer, such as CRC patients. Objective: To evaluate a new short food frequency questionnaire (NORDIET-FFQ), developed to estimate adherence to the Norwegian FBDG among CRC patients...
2018: Food & Nutrition Research
https://www.readbyqxmd.com/read/29537887/nutritional-information-provision-to-cancer-patients-and-their-relatives-can-promote-dietary-behavior-changes-independent-of-nutritional-information-needs
#18
Merel R van Veen, Renate M Winkels, Silvie H M Janssen, Ellen Kampman, Sandra Beijer
We investigated whether obtaining nutritional information influences reported changes in dietary behavior in cancer survivors and their relatives and whether nutritional information needs influence this association. We included 239 cancer survivors and their relatives, recruited from an online panel of cancer survivors and relatives. This panel completed a survey about their experiences with nutritional information provision by healthcare professionals and the media in the period after diagnosis, their information needs regarding nutrition and cancer, and whether they changed their dietary behavior since diagnosis...
March 14, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29533097/head-and-neck-cancer-patients-do-not-meet-recommended-intakes-of-micronutrients-without-consuming-fortified-products
#19
Sara Nejatinamini, Catherine Kubrak, Mirey Álvarez-Camacho, Vickie E Baracos, Sunita Ghosh, Wendy V Wismer, Vera C Mazurak
This study assessed dietary and micronutrient intakes of head and neck cancer (HNC) patients at key points in the disease trajectory and evaluated the contribution of oral nutritional supplements (ONS) to micronutrient intake. HNC patients (n = 114) completed a three-day dietary record and a tool to assess Nutrition Impact Scores (NIS) at baseline, post-treatment, and follow-up. Foods were classified into food categories. Micronutrient, protein, and energy intakes were compared to European Society for Parenteral and Enteral Nutrition guidelines for cancer patients...
March 13, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29530926/meat-cooking-methods-and-risk-of-type-2-diabetes-results-from-three-prospective-cohort-studies
#20
Gang Liu, Geng Zong, Kana Wu, Yang Hu, Yanping Li, Walter C Willett, David M Eisenberg, Frank B Hu, Qi Sun
OBJECTIVE: To examine open-flame and/or high-temperature cooking (grilling/barbecuing, broiling, or roasting) and doneness preferences (rare, medium, or well done) for red meat, chicken, and fish in relation to type 2 diabetes (T2D) risk among U.S. adults who consumed animal flesh regularly (≥2 servings/week). RESEARCH DESIGN AND METHODS: The prospective studies included 52,752 women from the Nurses' Health Study (NHS, followed during 1996-2012), 60,809 women from NHS II (followed during 2001-2013), and 24,679 men from the Health Professionals Follow-up Study (HPFS, followed during 1996-2012) who were free of diabetes, cardiovascular disease, and cancer at baseline...
March 12, 2018: Diabetes Care
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