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https://www.readbyqxmd.com/read/28821981/modifiable-factors-and-esophageal-cancer-a-systematic-review-of-published-meta-analyses
#1
REVIEW
Clara Castro, Bárbara Peleteiro, Nuno Lunet
There are marked differences in the etiology of the major histological types of esophageal cancer (EC)-squamous cell carcinomas (ESCC) and adenocarcinomas (EAC). This study aimed to summarize the current scientific knowledge on modifiable risk factors for EC, by histological type, through a systematic review of meta-analyses referenced in PubMed and ISI Web of Knowledge. We identified 100 meta-analyses on risk factors for ESCC (n = 54), EAC (n = 43), or EC (n = 51). ESCC risk significantly increased with alcohol and maté drinking, smoking, red and processed meat consumption and human papillomavirus infection, while it was negatively associated with body mass index and consumption of fruit, vegetables, white meat, folate, and some carotenoids...
August 18, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28818241/prevalence-of-modifiable-cancer-risk-factors-among-u-s-adults-aged-18-44-years
#2
Mary C White, Meredith L Shoemaker, Sohyun Park, Linda J Neff, Susan A Carlson, David R Brown, Dafna Kanny
INTRODUCTION: Carcinogen exposure and unhealthy habits acquired in young adulthood can set the stage for the development of cancer at older ages. This study measured the current prevalence of several cancer risk factors among young adults to assess opportunities to intervene to change the prevalence of these risk factors and potentially reduce cancer incidence. METHODS: Using 2015 National Health Interview Survey data (analyzed in 2016), the prevalence of potential cancer risk factors was estimated among U...
September 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28813467/meat-consumption-reduction-in-italian-regions-health-co-benefits-and-decreases-in-ghg-emissions
#3
Sara Farchi, Manuela De Sario, Enrica Lapucci, Marina Davoli, Paola Michelozzi
INTRODUCTION: Animal agriculture has exponentially grown in recent decades in response to the rise in global demand for meat, even in countries like Italy that traditionally eat a Mediterranean, plant-based diet. Globalization related dietary changes are contributing to the epidemic of non-communicable diseases and to the global climate crisis, and are associated with huge carbon and water footprints. The objective of the study is to assess inequalities in health impacts and in attributable greenhouse gases-GHG emissions in Italy by hypothesizing different scenarios of reduction in red and processed meat consumption towards healthier consumption patterns more compliant with the recommendations of the Mediterranean food pyramid...
2017: PloS One
https://www.readbyqxmd.com/read/28804436/intake-of-different-types-of-red-meat-poultry-and-fish-and-incident-colorectal-cancer-in-women-and-men-results-from-the-malm%C3%A3-diet-and-cancer-study
#4
Alexandra Vulcan, Jonas Manjer, Ulrika Ericson, Bodil Ohlsson
Background : Colorectal cancer (CRC) is considered one of the most common forms of cancer in the Western world. High intake of red and processed meat is considered to increase CRC development. Objective : This study examined associations between intake of red meats, poultry, and fish and incident CRC, and if weight status modifies the associations. Design : In the Malmö Diet and Cancer Study, dietary data was collected through a modified diet history method. Via the Swedish Cancer Registry, 728 cases of CRC were identified during 428 924 person-years of follow-up of 16 944 women and 10 987 men...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28798944/diet-alcohol-use-and-colorectal-cancer-screening-among-black-church-goers
#5
Nga T Nguyen, Elaine J Savoy, Lorraine R Reitzel, Minh-Anh H Nguyen, David W Wetter, Jacqueline Reese-Smith, Lorna H McNeill
OBJECTIVES: Interventions for colorectal cancer (CRC) prevention among black adults are needed. Connections between CRC screening non-adherence and other health risk behaviors may inform intervention development. METHODS: Associations between red meat (RM) and fruit and vegetable (FV) consumption, at-risk alcohol use, and CRC ever-screening were examined using adjusted logistic regressions among 520 church-going black adults in Houston, Texas, aged >50. RESULTS: In the final adjusted model, being younger, uninsured, eating more RM and engaging in at-risk alcohol use were associated with lower likelihood of CRC ever-screening...
March 2017: Health Behavior and Policy Review
https://www.readbyqxmd.com/read/28795217/animals-living-in-polluted-environments-are-a-potential-source-of-anti-tumor-molecule-s
#6
REVIEW
Shareni Jeyamogan, Naveed Ahmed Khan, Ruqaiyyah Siddiqui
Despite advances in therapeutic interventions and supportive care, the morbidity and mortality associated with cancer have remained significant. Thus, there is a need for newer and more powerful anti-tumor agents. The search for new anti-tumor compounds originating from natural resources is a promising research area. Animals living in polluted environments are a potent source of anti-tumor agents. Under polluted milieus, species such as crocodiles, feed on rotten meat, are exposed to heavy metals, endure high levels of radiation, and are among the very few species to survive the catastrophic Cretaceous-Tertiary extinction event with a prolonged lifespan...
August 9, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28792013/a-summary-of-meat-intakes-and-health-burdens
#7
REVIEW
C S C Yip, W Lam, R Fielding
This review summarizes published meta-analysis outcomes on the associations between meat intakes and burden of diseases. A novel assessment process was developed, combining selected Cochrane Review measures, AMSTAR checklist, and other quality measures identified by authors during preliminary phases of the review process. Meat intakes have been found to be statistically significant associated with 21 burden of diseases. A total of 37 risk-outcome best dose-response estimations were identified, all were positively associated, and 21 of them with low to moderate, or insignificant heterogeneity...
August 9, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28783055/usual-choline-intakes-are-associated-with-egg-and-protein-food-consumption-in-the-united-states
#8
Taylor C Wallace, Victor L Fulgoni
Choline is an essential nutrient with critical roles in several biological processes including neuronal development, cell signaling, nerve impulse transmission, and lipid transport and metabolism. The National Cancer Institute method was used to assess usual intakes of choline from foods according to data for participants enrolled in the National Health and Nutrition Examination Survey 2009-2014 datasets and pregnant women in the 2005-2014 datasets. Suboptimal intakes of choline are present across many gender and life-stage subpopulations, as well as pregnant women in the U...
August 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28746932/morbidity-and-functional-outcomes-following-free-jejunal-flap-reconstruction-for-head-and-neck-cancer
#9
Song Ni, Yiming Zhu, Dong Qu, Jian Wang, Dezhi Li, Bin Zhang, Zhengang Xu, Shaoyan Liu
AIM: To evaluate the morbidity and fundamental functional outcomes (swallow and speech) after free jejunal flap (FJF) reconstruction following total pharyngolaryngo-esophagectomy (PLE) in China. METHODS: 18 patients with FJF reconstruction after total PLE were retrospectively reviewed. Scheduled barium swallow test was performed 7-10 days postoperatively. Rehabilitation of swallowing and speech for patients was assessed by the Performance Status Scale for Head and Neck Cancer Patients...
July 27, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28745644/profiling-anti-neu5gc-igg-in-human-sera-with-a-sialoglycan-microarray-assay
#10
Shani Leviatan Ben-Arye, Hai Yu, Xi Chen, Vered Padler-Karavani
Cells are covered with a cloak of carbohydrate chains (glycans) that is commonly altered in cancer and that includes variations in sialic acid (Sia) expression. These are acidic sugars that have a 9-carbon backbone and that cap vertebrate glycans on cell surfaces. Two of the major Sia forms in mammals are N-acetylneuraminic acid (Neu5Ac) and its hydroxylated form, N-glycolylneuraminic acid (Neu5Gc). Humans cannot produce endogenous Neu5Gc due to the inactivation of the gene encoding cytidine 5'monophosphate-Neu5Ac (CMP-Neu5Ac) hydroxylase (CMAH)...
July 13, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28741383/adherence-to-mediterranean-diet-and-metabolic-syndrome-in-brca-mutation-carriers
#11
Eleonora Bruno, Siranoush Manoukian, Elisabetta Venturelli, Andreina Oliverio, Francesca Rovera, Giovanna Iula, Daniele Morelli, Bernard Peissel, Jacopo Azzolini, Eliana Roveda, Patrizia Pasanisi
BACKGROUND: Insulin resistance is associated with higher breast cancer (BC) penetrance in BRCA mutation carriers. Metabolic syndrome (MetS), an insulin resistance syndrome, can be reversed by adhering to the Mediterranean diet (MedDiet). In a dietary intervention trial on BRCA mutation carriers, we evaluated adherence to the MedDiet, and the association with the MetS, by analyzing data from the Mediterranean Diet Adherence Screener (MEDAS). METHODS: BRCA mutation carriers, with or without BC, aged 18 to 70 years, were eligible for the trial...
July 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28736047/health-risk-assessment-as-an-approach-to-manage-an-old-landfill-and-to-propose-integrated-solid-waste-treatment-a-case-study-in-italy
#12
O Paladino, M Massabò
The aim of the present paper is to show how an approach based on human health risk analysis can be used as a decisional tool for the evaluation of impacts on population and for deciding between different waste treatment processes. The situation in which the increasing production of solid wastes cannot be confined in the old existing Municipal Solid Waste landfill (settled in Genoa, Liguria Region, Italy) is used as a case study. Risk assessment for human health due to air, surface water, groundwater and soil contamination is performed in different scenarios for the old landfill and compared with alternative Waste-to-Energy management solutions that consider thermal treatment by gasification of the total waste or gasification of the dry fraction coupled with anaerobic digestion of the wet fraction, plus biogas combustion with or without sludge and bottom ash/slag disposal in the old landfill...
July 20, 2017: Waste Management
https://www.readbyqxmd.com/read/28735743/exposure-to-meat-derived-carcinogens-and-bulky-dna-adduct-levels-in-normal-appearing-colon-mucosa
#13
Vikki Ho, Vanessa Brunetti, Sarah Peacock, Thomas E Massey, Roger W L Godschalk, Frederik J van Schooten, Janet E Ashbury, Stephen J Vanner, Will D King
INTRODUCTION: Meat consumption is a risk factor for colorectal cancer. This research investigated the relationship between meat-derived carcinogen exposure and bulky DNA adduct levels, a biomarker of DNA damage, in colon mucosa. METHODS: Least squares regression was used to examine the relationship between meat-derived carcinogen exposure (PhIP and meat mutagenicity) and bulky DNA adduct levels in normal-appearing colon tissue measured using (32)P-postlabelling among 202 patients undergoing a screening colonoscopy...
September 2017: Mutation Research
https://www.readbyqxmd.com/read/28733869/bmi-is-a-risk-factor-for-colorectal-cancer-mortality
#14
Aasma Shaukat, Allison Dostal, Jeremiah Menk, Timothy R Church
BACKGROUND: The relationship between dietary and lifestyle risk factors and long-term mortality from colorectal cancer is poorly understood. Several factors, such as obesity, intakes of red meat, and use of aspirin, have been reported to be associated with risk of colorectal cancer mortality, though these findings have not been replicated in all studies to date. METHODS: In the Minnesota Colon Cancer Control Study, 46,551 participants 50-80 years old were randomly assigned to usual care (control) or annual or biennial screening by fecal occult blood testing...
July 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28720273/meeting-psychosocial-and-health-information-needs-to-ensure-quality-of-cancer-care-in-outpatients
#15
Maria Francesca Piazza, Maura Galletta, Igor Portoghese, Ilaria Pilia, Maria Teresa Ionta, Paolo Contu, Alessandra Mereu, Marcello Campagna
PURPOSE: The purpose of this study was to investigate patients' and caregivers' health needs for a re-orientation program based on principles of health promotion in an Oncology Department from an Italian University Hospital. METHOD: A Cross-sectional design with qualitative and quantitative approaches was used. Participants included cancer patients and their caregivers. Information about disease concerns were collected using a survey form. Information about healthy lifestyle was obtained using motivational interviews...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28714190/polymorphisms-of-xenobiotic-metabolizing-genes-and-colorectal-cancer-risk-in-patients-with-lynch-syndrome-a-retrospective-cohort-study-in-taiwan
#16
Abram Bunya Kamiza, Jeng-Fu You, Wen-Chang Wang, Reiping Tang, Chun-Yu Chang, Huei-Tzu Chien, Chih-Hsiung Lai, Li-Ling Chiu, Tsai-Ping Lo, Kuan-Yi Hung, Chao A Hsiung, Chih-Ching Yeh
Cytochrome P450 (CYP), glutathione-S-transferase (GST), and N-acetyltransferase (NAT) are crucial for metabolism and clearance of xenobiotics. This study investigated whether CYP, GST, and NAT single nucleotide polymorphisms (SNPs) are associated with colorectal cancer (CRC) in patients with Lynch syndrome. The interaction between these SNPs and cigarette smoking or meat consumption was also explored. We identified 270 patients with Lynch syndrome from the Taiwan Hereditary Nonpolyposis Colorectal Cancer Consortium...
July 17, 2017: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/28687643/cancer-incidence-attributable-to-lifestyle-and-environmental-factors-in-alberta-in-2012-summary-of-results
#17
Anne Grundy, Abbey E Poirier, Farah Khandwala, Xin Grevers, Christine M Friedenreich, Darren R Brenner
BACKGROUND: Estimates of the proportion of cancer cases that can be attributed to modifiable risk factors are not available for Canada and, more specifically, Alberta. The purpose of this study was to estimate the total proportion of cancer cases in Alberta in 2012 that could be attributed to a set of 24 modifiable lifestyle and environmental risk factors. METHODS: We estimated summary population attributable risk estimates for 24 risk factors (smoking [both passive and active], overweight and obesity, inadequate physical activity, diet [inadequate fruit and vegetable consumption, inadequate fibre intake, excess red and processed meat consumption, salt consumption, inadequate calcium and vitamin D intake], alcohol, hormones [oral contraceptives and hormone therapy], infections [Epstein-Barr virus, hepatitis B and C viruses, human papillomavirus, Helicobacter pylori], air pollution, natural and artificial ultraviolet radiation, radon and water disinfection by-products) by combining population attributable risk estimates for each of the 24 factors that had been previously estimated...
July 7, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28681185/inhalation-exposure-to-pm-bound-polycyclic-aromatic-hydrocarbons-released-from-barbecue-grills-powered-by-gas-lump-charcoal-and-charcoal-briquettes
#18
Artur J Badyda, Kamila Widziewicz, Wioletta Rogula-Kozłowska, Grzegorz Majewski, Izabela Jureczko
The present study seeks to define the possible cancer risk arising from the inhalation exposure to particle (PM)-bound polycyclic aromatic hydrocarbons (PAHs) present in barbecue emission gases and to compare the risk depending on the type of fuel used for grill powering. Three types of fuel were compared: liquid propane gas, lump charcoal, and charcoal briquettes. PM2.5 and PM2.5-100 were collected during grilling. Subsequently, 16 PAHs congeners were extracted from the PM samples and measured quantitatively using gas chromatography...
July 6, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28677516/seroepidemiology-of-toxoplasma-gondii-infection-in-patients-with-liver-disease-in-eastern-china
#19
A L Tian, G X Li, H M Elsheikha, D S Gardner, X Y Zhang, W Dong, X P Yang, Y Y Luo, H L Li, W Cong, X Q Zhu
The role of the protozoan parasite Toxoplasma gondii in the pathogenesis of liver disease has recently gained much interest. The aim of this study was to determine the prevalence and risk factors associated with T. gondii infection in patients with liver disease from three cities in Shandong and Henan provinces, China. A case-control study was conducted from December 2014 to November 2015 and included 1142 patients with liver disease and 1142 healthy controls. Serum samples were collected from all individuals and were examined with enzyme-linked immunosorbent assay for the presence of anti-T...
August 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28666313/an-update-of-the-wcrf-aicr-systematic-literature-review-and-meta-analysis-on-dietary-and-anthropometric-factors-and-esophageal-cancer-risk
#20
S Vingeliene, D S M Chan, A R Vieira, E Polemiti, C Stevens, L Abar, D Navarro Rosenblatt, D C Greenwood, T Norat
Background: In the 2007 World Cancer Research Fund/American Institute for Cancer Research Second Expert Report, the expert panel judged that there was strong evidence that alcoholic drinks and body fatness increased esophageal cancer risk, whereas fruits and vegetables probably decreased its risk. The judgments were mainly based on case-control studies. As part of the Continuous Update Project (CUP), we updated the scientific evidence accumulated from cohort studies in this topic. Methods: We updated the CUP database up to 10 January, 2017 by searching in PubMed and conducted dose-response meta-analyses to estimate summary relative risks (RRs) and 95% confidence intervals (CIs) using random effects model...
June 29, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
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