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https://www.readbyqxmd.com/read/28094544/red-wine-and-pomegranate-extracts-suppress-cured-meat-promotion-of-colonic-mucin-depleted-foci-in-carcinogen-induced-rats
#1
Nadia M Bastide, Nathalie Naud, Gilles Nassy, Jean-Luc Vendeuvre, Sylviane Taché, Françoise Guéraud, Ditte A Hobbs, Gunter G Kuhnle, Denis E Corpet, Fabrice H F Pierre
Processed meat intake is carcinogenic to humans. We have shown that intake of a workshop-made cured meat with erythorbate promotes colon carcinogenesis in rats. We speculated that polyphenols could inhibit this effect by limitation of endogenous lipid peroxidation and nitrosation. Polyphenol-rich plant extracts were added to the workshop-made cured meat and given for 14 days to rats and 100 days to azoxymethane-induced rats to evaluate the inhibition of preneoplastic lesions. Colons of 100-d study were scored for precancerous lesions (mucin-depleted foci, MDF), and biochemical end points of peroxidation and nitrosation were measured in urinary and fecal samples...
January 17, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28073766/a-comprehensive-model-of-colorectal-cancer-by-risk-factor-status-and-subsite-using-data-from-the-nurses-health-study
#2
Esther K Wei, Graham A Colditz, Edward L Giovannucci, Kana Wu, Robert J Glynn, Charles S Fuchs, Meir Stampfer, Walter Willett, Shuji Ogino, Bernard Rosner
We expanded and updated our colon cancer risk model to evaluate colorectal cancer (CRC) and whether subsite-specific risk models are warranted. Using data from 1980-2010 for 90,286 women enrolled in the Nurses' Health Study, we performed competing-risks regression and tests for subsite heterogeneity (proximal colon: n = 821; distal colon: n = 521; rectum: n = 376). Risk factors for CRC were consistent with those in our colon cancer model. Processed meat consumption was associated with a higher risk of distal (hazard ratio (HR) = 1...
January 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28070638/red-and-processed-meat-consumption-and-risk-of-bladder-cancer-a-dose-response-meta-analysis-of-epidemiological-studies
#3
Alessio Crippa, Susanna C Larsson, Andrea Discacciati, Alicja Wolk, Nicola Orsini
BACKGROUND/OBJECTIVES: Several epidemiological studies have analyzed the associations between red and processed meat and bladder cancer risk but the shape and strength of the associations are still unclear. Therefore, we conducted a dose-response meta-analysis to quantify the potential association between red and processed meat and bladder cancer risk. METHODS: Relevant studies were identified by searching the PubMed database through January 2016 and reviewing the reference lists of the retrieved articles...
December 22, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/28057711/higher-consumption-of-grilled-barbecued-and-smoked-meat-linked-to-increased-mortality-risk-among-breast-cancer-survivors
#4
(no author information available yet)
No abstract text is available yet for this article.
June 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28053921/what-are-the-links-of-prostate-cancer-with-physical-activity-and-nutrition-a-systematic-review-article
#5
REVIEW
Joanna Kruk, Hassan Aboul-Enein
BACKGROUND: Prostate cancer (PCa) is the second most common malignancy in men worldwide. The purpose of this study was to provide a brief synthesis the current knowledge for the effects of physical activity (PA) and nutrition on PCa risk. METHODS: A systematic review of English languages reviews, meta-analysis, and original articles published from 2009 to 2015 extracted from the following websites: MEDLINE, Web of Science, Health Source, Science Direct, and their references...
December 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28053001/cancer-cachexia-differentially-regulates-visceral-adipose-tissue-turnover
#6
Felipe de Oliveira Franco, Magno Alves Lopes, Felipe dos Santos Henriques, Rodrigo X Neves, Cesário Bianchi Filho, Miguel Luiz Batista
Cancer cachexia (CC) is a progressive metabolic syndrome that is marked by severe body weight loss. Metabolic disarrangement of fat tissues is a very early event in CC, followed by adipose tissue (AT) atrophy and remodelling. However, there is little information regarding the possible involvement of cellular turnover in this process. Thus, we evaluated the effect of CC on AT turnover of mesenteric (ME) and retroperitoneal (RP) AT depots as possible factors that contribute to AT atrophy. CC was induced by a subcutaneous injection of Walker tumour cells (2x10(7)) in Wistar rats...
4, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28052933/grilled-barbecued-and-smoked-meat-intake-and-survival-following-breast-cancer
#7
Humberto Parada, Susan E Steck, Patrick T Bradshaw, Lawrence S Engel, Kathleen Conway, Susan L Teitelbaum, Alfred I Neugut, Regina M Santella, Marilie D Gammon
BACKGROUND: Grilled, barbecued, and smoked meat intake, a prevalent dietary source of polycyclic aromatic hydrocarbon (PAH) carcinogens, may increase the risk of incident breast cancer. However, no studies have examined whether intake of this PAH source influences survival after breast cancer. METHODS: We interviewed a population-based cohort of 1508 women diagnosed with first primary invasive or in situ breast cancer in 1996 and 1997 at baseline and again approximately five years later to assess grilled/barbecued and smoked meat intake...
June 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28018893/cancer-incidence-attributable-to-red-and-processed-meat-consumption-in-alberta-in-2012
#8
Anne Grundy, Abbey E Poirier, Farah Khandwala, Alison McFadden, Christine M Friedenreich, Darren R Brenner
BACKGROUND: Consumption of red and processed meats has been associated with an increased risk of colorectal cancer. The purpose of this study was to estimate the proportion and absolute number of cancers in Alberta in 2012 that could be attributed to the consumption of red and processed meat. METHODS: The number and proportion of colorectal cancers in Alberta that were attributable to red and processed meat consumption were estimated using population attributable risk...
October 2016: CMAJ Open
https://www.readbyqxmd.com/read/27997546/the-eatwell-guide-modelling-the-health-implications-of-incorporating-new-sugar-and-fibre-guidelines
#9
Linda J Cobiac, Peter Scarborough, Asha Kaur, Mike Rayner
OBJECTIVE: To model population health impacts of dietary changes associated with the redevelopment of the UK food-based dietary guidelines (the 'Eatwell Guide'). METHOD: Using multi-state lifetable methods, we modelled the impact of dietary changes on cardiovascular disease, diabetes and cancers over the lifetime of the current UK population. From this model, we determined change in life expectancy and disability-adjusted life years (DALYs) that could be averted...
2016: PloS One
https://www.readbyqxmd.com/read/27989995/the-cancer-risk-related-to-meat-and-meat-products
#10
REVIEW
Ian T Johnson
INTRODUCTION: Meat has been classified by International Agency for Research on Cancer (IARC) as carcinogenic to humans. The evidence and the implications for health are reviewed. SOURCES OF DATA: Evidence was obtained from published reports and systematic reviews published before and since the IARC decision. AREAS OF AGREEMENT: Epidemiology indicates that processed meat products are associated with increased risk of colorectal cancer. Evidence for red meat and for other cancers remains tentative...
December 18, 2016: British Medical Bulletin
https://www.readbyqxmd.com/read/27988219/dietary-changes-impact-the-gut-microbe-composition-in-overweight-and-obese-men%C3%A2-with-prostate-cancer-undergoing-radical%C3%A2-prostatectomy
#11
Andrew D Frugé, Travis Ptacek, Yuko Tsuruta, Casey D Morrow, Maria Azrad, Renee A Desmond, Gary R Hunter, Soroush Rais-Bahrami, Wendy Demark-Wahnefried
BACKGROUND: Diet and obesity influence prostate cancer risk and progression-effects that may be mediated through the gut microbiome. OBJECTIVE: Our aim was to explore relationships among diet, gut microbes, and Gleason sum in overweight and obese prostate cancer patients enrolled in a presurgical weight-loss trial. DESIGN: Randomized controlled trial (NCT01886677) secondary analysis. PARTICIPANTS/SETTING: In 2013-2014, 40 prostate cancer patients in the southeastern United States were randomized and allocated equally to weight-loss and wait-list control arms while they awaited prostatectomy; stool samples were collected on a subset of 22 patients...
December 14, 2016: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27984695/mass-spectrometric-characterization-of-an-acid-labile-adduct-formed-with-2-amino-1-methyl-6-phenylimidazo-4-5-b-pyridine-and-albumin-in-humans
#12
Yi Wang, Peter W Villalta, Lijuan Peng, Karen Dingley, Michael A Malfatti, K W Turteltaub, Robert J Turesky
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic aromatic amine formed during the high-temperature cooking of meats. The cytochrome P450-mediated N-hydroxylation of the exocyclic amine group of PhIP produces 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, an electrophilic metabolite that forms adducts with DNA and proteins. Previous studies conducted by our laboratory showed that the reaction of N-oxidized PhIP metabolites with human albumin in vitro primarily occurs at the Cys(34) residue, to produce an acid-labile linked sulfinamide adduct...
January 18, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/27977648/modifiable-lifestyle-factors-that-could-reduce-the-incidence-of-colorectal-cancer-in-new-zealand
#13
Ann Richardson, James Hayes, Chris Frampton, John Potter
AIM: To estimate population attributable fractions for modifiable lifestyle factors and colorectal cancer in New Zealand. METHOD: Relative risks for lifestyle risk factors for colorectal cancer, and population data on the prevalence of exposure in New Zealand, were used to estimate the population attributable fraction (PAF) for each risk factor. RESULTS: Six modifiable lifestyle risk factors were identified. The PAFs for these risk factors were 9% for obesity, 7% for alcohol, 4% for physical inactivity, 3% for smoking, 5% for consumption of red meat and 3% for processed meat...
December 16, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27975054/diet-lifestyles-family-history-and-prostate-cancer-incidence-in-an-east-algerian-patient-group
#14
Somia Lassed, Cláudia M Deus, Nuno Lourenço, Abderrezak Dahdouh, Albert A Rizvanov, Paulo J Oliveira, Djamila Zama
Prostate cancer (PC) is the fourth most common cancer in men and the sixth leading cause of death in Algeria. To examine the relationship between lifestyle factors, including diet, and family history and PC risk, a case-control study was performed in an eastern Algerian population, comprising 90 patients with histologically confirmed PC and 190 controls. Data collection was carried out through a structured questionnaire and statistical analysis was performed to evaluate the different variables. The data showed that consumption of lamb and beef meat and high intake of animal fat and dairy products increased PC risk...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27968878/dietary-patterns-and-risk-of-breast-cancer-in-chinese-women-a-population-based-case-control-study
#15
Shurong Lu, Xingyu Huang, Hao Yu, Jie Yang, Renqiang Han, Jian Su, Wencong Du, Jinyi Zhou, Xiaojin Yu, Ming Wu
BACKGROUND: The incidence rate of breast cancer has markedly increased in recent years in China, yet the association of breast cancer with dietary patterns such as a Chinese traditional diet has not been studied. We aimed to examine this association among women from the Jiangsu Province of China. METHODS: In this case-control study, we used the data from local population-based cancer registry agency to recruit newly diagnosed patients with primary breast cancer as cases...
October 2016: Lancet
https://www.readbyqxmd.com/read/27958255/evaluation-of-serum-vitamin-b12-level-and-related-nutritional-status-among-apparently-healthy-obese-female-individuals
#16
D Baltaci, M H Deler, Y Turker, F Ermis, D Iliev, U Velioglu
OBJECTIVE: Obesity is a major public health problem and great risk for not only cardiovascular diseases but also cancer, musculoskeletal, and gynecological diseases. This study was aimed to investigate the association between serum Vitamin B12 (vitB12), body mass index (BMI), and nutritional status among obese women. METHODS: This cross-sectional study enrolled consecutive female subjects. The consumptions of red meat, fish, bovine liver, egg, and mushroom were recorded...
January 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/27956118/genetic-polymorphisms-of-phase-i-metabolizing-enzyme-genes-their-interaction-with-lifetime-grilled-and-smoked-meat-intake-and-breast-cancer-incidence
#17
Humberto Parada, Susan E Steck, Rebecca J Cleveland, Susan L Teitelbaum, Alfred I Neugut, Regina M Santella, Marilie D Gammon
PURPOSE: To examine associations between 22 CYP single nucleotide polymorphisms (SNPs) and breast cancer incidence and their interactions with grilled-smoked meat intake, a source of polycyclic aromatic hydrocarbons. METHODS: White women with first primary in situ or invasive breast cancer (n = 988) and frequency-matched controls (n = 1021) from a population-based study were interviewed to assess lifetime grilled-smoked meat intake. SNPs with minor allele frequencies of greater than 0...
November 25, 2016: Annals of Epidemiology
https://www.readbyqxmd.com/read/27930524/dietary-protein-and-fat-intake-in-relation-to-risk-of-colorectal-adenoma-in-korean
#18
Sun Young Yang, Young Sun Kim, Jung Eun Lee, Jueun Seol, Ji Hyun Song, Goh Eun Chung, Jeong Yoon Yim, Sun Hee Lim, Joo Sung Kim
Consumption of red meat and alcohol are known risk factors for colorectal cancer, but associations for dietary fat remain unclear. We investigated the associations of dietary fat, protein, and energy intake with prevalence of colorectal adenoma.We performed a prospective cross-sectional study on asymptomatic persons who underwent a screening colonoscopy at a single center during a routine health check-up from May to December 2011. Dietary data were obtained via a validated Food Frequency Questionnaire (FFQ), assisted by a registered dietician...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27918906/diet-and-the-risk-of-head-and-neck-cancer-among-never-smokers-and-smokers-in-a-chinese-population
#19
Carrie Butler, Yuan-Chin Amy Lee, Shuang Li, Qian Li, Chien-Jen Chen, Wan-Lun Hsu, Pen-Jen Lou, Cairong Zhu, Jian Pan, Hongbing Shen, Hongxia Ma, Lin Cai, Baochang He, Yu Wang, Xiaoyan Zhou, Qinghai Ji, Baosen Zhou, Wei Wu, Jie Ma, Paolo Boffetta, Zuo-Feng Zhang, Min Dai, Mia Hashibe
BACKGROUND: Few studies have been conducted in China to investigate the association between diet and the risk of head-and-neck cancer (HNC). The aim of this study was to determine the relationship between diet and HNC risk in the Chinese population and to examine whether smoking status has any effect on the risk. METHODS: Our multicenter case-control study included 921 HNC cases and 806 controls. We obtained information on the frequency of both animal- and plant-based food consumption...
December 2, 2016: Cancer Epidemiology
https://www.readbyqxmd.com/read/27913919/a-critical-overview-on-the-biological-and-molecular-features-of-red-and-processed-meat-in-colorectal-carcinogenesis
#20
REVIEW
Arunan Jeyakumar, Lakal Dissabandara, Vinod Gopalan
A recent investigation by the World Health Organisation (WHO) has found that the consumption of processed meat and potentially red meat promotes carcinogenesis and can increase the risk of colorectal cancer. This literature review aims to summarise both the red and processed meat molecules associated with colorectal carcinogenesis and investigate their relationship with the pathogenic process of colorectal cancer. Literature relating to the carcinogenic effect of red and processed meat molecules was critically reviewed...
December 2, 2016: Journal of Gastroenterology
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