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Tomohiko Sakatani, Satoshi Shimoo, Kazuaki Takamatsu, Atsushi Kyodo, Yumika Tsuji, Kayoko Mera, Masahiro Koide, Koji Isodono, Yoshinori Tsubakimoto, Akiko Matsuo, Keiji Inoue, Hiroshi Fujita
BACKGROUND: Myocardial perfusion single-photon emission-computed tomography (SPECT) can predict cardiac events in patients with coronary artery disease with high accuracy; however, pseudo-negative cases sometimes occur. Heart Risk View, which is based on the prospective cohort study (J-ACCESS), is a software for evaluating cardiac event probability. OBJECTIVES: We examined whether Heart Risk View was useful to evaluate the cardiac risk in patients with normal myocardial perfusion SPECT (MPS)...
August 19, 2016: Annals of Nuclear Medicine
Yuuto Kawashima, Hiroyasu Takahashi, Megumi Shimoo, Yukino Tamamura, Yoshiharu Ishikawa, Koichi Kadota
A large subcutaneous mass, formed on the left lower jaw of a 4-month-old Japanese Black male calf, was partially excised for histological and bacteriological examinations. Antibiotic treatment resulted in a good prognosis. Bacteria isolated from the excised material were characterized by weak hemolysis and positive reactions for catalase and oxidase, and were 99% identical to Mannheimia granulomatis strains. The presence of the leukotoxin gene product was demonstrated by polymerase chain reaction amplification...
July 1, 2016: Journal of Veterinary Medical Science
Takahito Ando, Yoshiaki Shimoo, Masayoshi Nakasato, Hisahiro Yoshida
To provide safe dental care, it is important to minimize the pain associated with the initial injection of the local anesthetic. For this purpose, a topical anesthetic is preliminarily applied to the area where a needle will be inserted in a clinical setting. In this study, we prepared new topical anesthetic formulations with favorable intra-oral retentivity and an excellent anesthetic effect, and clinically evaluated their efficacy. We used 4% lidocaine solution as an anesthetic drug and gelatin, agar, and a food thickener as a base to prepare new topical anesthetic formulations...
2016: Biological & Pharmaceutical Bulletin
Junichi Sato, Goro Watanabe, Masami Ando, Yoshiaki Shimoo, Kazushige Shizukuda, Tomonori Kimura, Mariko Kobayashi
STATEMENT OF PROBLEM: Although 1-piece implants are associated with positive clinical outcomes, including improved implant stability, overall survival rate, and marginal bone levels, a few studies have suggested that 1-piece implants have low success rates. PURPOSE: This prospective multicenter study evaluated the efficacy of 1-piece implants placed in immediate function in private clinic-based and hospital-based settings with a focus on marginal bone level changes and esthetic outcomes over a 3-year follow-up period...
October 2014: Journal of Prosthetic Dentistry
Freddy Thomas, Eric Jamin, Katsuya Shimoo, Junji Nagao, Yukihiko Osaki, Colin Granier
Continuous-flow isotope ratio mass spectrometry (CF-IRMS) of deuterium, carbon, nitrogen, oxygen and sulfur has been used to analyse samples of pure chondroitin sulfates from known animal sources (shark, squid, salmon, pig and bovine). There is a need to control the origin of this dietary supplement, which is extracted from several types of animals: for traditional, ethical, or economic reasons, a given source of natural products of animal origin can be preferred to another, and can therefore have a different price...
September 15, 2011: Rapid Communications in Mass Spectrometry: RCM
Shinichi Abe, Emi Hiroki, Osamu Iwanuma, Koji Sakiyama, Yoshitaka Shirakura, Daiki Hirose, Yoshiaki Shimoo, Masashi Suzuki, Yasutoyo Ikari, Ryusuke Kikuchi, Yoshinobu Ide, Masao Yoshinari
Mammals exhibit marked morphological differences in the muscles surrounding the jaw bone due to differences in eating habits. Furthermore, the myofiber properties of the muscles differ with function. Since the muscles in the oral region have various functions such as eating, swallowing, and speech, it is believed that the functional role of each muscle differs. Therefore, to clarify the functional role of each masticatory muscle, the myofiber properties of the adult mouse masticatory muscles were investigated at the transcriptional level...
May 2008: Bulletin of Tokyo Dental College
Toshiro Arai, Akira Inoue, Akira Takeguchi, Hisashi Mizutani, Megumi Shimoo, Toshinori Sako, Itaru Yoshimura, Nobuhiro Kimura
Concentrations of plasma glucose, immunoreactive insulin (IRI) and free fatty acid (FFA) and activities of enzymes related to energy metabolism and lactate dehydrogenase (LDH) isoenzyme pattern in plasma and leukocytes were investigated in lactating Holstein cows (dairy cattle) and fattening Japanese Black Wagyu x Holstein steers (beef cattle). IRI concentrations and LDH and malate dehydrogenase (MDH) activities in the plasma of beef cattle were significantly higher than those in dairy cattle. The cytosolic ratio of MDH/LDH activity in the leukocytes of beef cattle was significantly higher than that of dairy cattle...
November 2003: Journal of Veterinary Medical Science
Jun Shiraishi, Tetsuya Tatsumi, Kazutoshi Shimoo, Asako Katsume, Hiroki Mani, Miyuki Kobara, Takeshi Shirayama, Akihiro Azuma, Masao Nakagawa
A 59-year-old woman with skin sarcoidosis was admitted to hospital for assessment of complete atrioventricular block. Cross-sectional echocardiography showed that the apical free wall of the right ventricle was thin and dyskinetic with dilation of the right ventricle. Thallium-201 myocardial imaging revealed a normal distribution. Both gallium-67 and technetium-99m pyrophosphate scintigraphy revealed no abnormal uptake in the myocardium. Right ventriculography showed chamber dilation and dyskinesis of the apical free wall, whereas left ventriculography showed normokinesis, mimicking right ventricular dysplasia...
February 2003: Circulation Journal: Official Journal of the Japanese Circulation Society
Y Kurono, M Egawa, T Yano, K Shimoo
The Neiguan acupuncture point (EH-6) of the heart meridian is often used for circulatory disorders. To clarify this effect, we measured coronary diameters in patients with angina pectoris following acupuncture stimulation using cardioangiography. Two kinds of acupuncture stimulation, the leaving needle (LN) and the sparrow pecking method (SPM), were employed for this study. No significant differences were found between LN and SPM. Concerning the pattern of coronary reaction, coronary constriction following acupuncture showed a relationship to patients with vasospastic angina...
2002: American Journal of Chinese Medicine
F Hongo, M Saitoh, K Tsuruyama, K Shimoo, Y Yamamura
An 81-year-old man complaining of appetite loss visited our clinic. Four subcutaneous nodules were visible. One was seen on the right chest, 1 on the left shoulder and 2 on the abdomen. They were soft, dome-like masses and 20 to 30 mm in diameter. Computed tomography revealed multiple metastatic lesions in the brain, lungs, abdomen and skin. The patient had undergone radical nephrectomy for renal cell carcinoma 15 years earlier. The histology of the biopsy specimens obtained at nephrectomy was grade 1 and that of the subcutaneous nodules was grade 2...
June 1999: Hinyokika Kiyo. Acta Urologica Japonica
Y Kubota, H Sugihara, T Nakagawa, S Inagaki, N Inoue, A Azuma, K Shimoo, K Furukawa, H Katsume, H Ijichi
To evaluate right ventricular (RV) function in severe left ventricular (LV) failure, we measured RV and LV ejection fractions (EF) in 18 patients with old myocardial infarction (OMI) and in 18 with dilated cardiomyopathy (DCM) using cardiac blood pool scintigraphy. In patients with OMI, RVEF was significantly greater in stage II LV failure than in stage III (functional class of the New York Heart Association, 47 +/- 8% and 28 +/- 12%, respectively: p less than 0.01), and this correlated well with exercise tolerance by bicycle ergometer and mean pulmonary artery pressure (r = 0...
December 1987: Journal of Cardiology
T Tatsumi, T Sirayama, H Tatsukawa, Y Kosugi, T Okada, A Azuma, I Omori, N Inoue, K Shimoo, T Nakagawa
No abstract text is available yet for this article.
September 1988: Kokyu to Junkan. Respiration & Circulation
T Kuribayashi, T Mizuta, K Shimoo, Y Kubota, H Katsume, M Nakagawa, Y Ibata
We performed gross-anatomic and histologic examinations quantitatively on 18 male and 30 female WKY/NCrj rats, and their 299 first generation off spring. The results were analyzed in comparison with those obtained from 3 other strains of rats. The offspring of the WKY rats showed various cardiac abnormalities quite similar to those in their parents. The cardiac abnormalities in the offspring of the WKY rats were: increased heart weight (in about 10%), left or right atrial hypertrophy (50%), disproportionate septal thickening (50%), small left ventricular cavity (40%), right ventricular hypertrophy (40%), abnormal fiber arrangement greater than 5% in either of the 3 ventricular walls (90%), myocardial fibrosis (70%), and abnormal location of arteries in the ventricular septum (30%)...
October 1988: Japanese Circulation Journal
T Nakagawa, H Sugihara, T Katahira, K Shiga, S Inagaki, Y Kubota, I Omori, A Azuma, N Inoue, K Shimoo
To evaluate the myocardial perfusion during transient coronary occlusion, we attempted to obtain the myocardial scintigraphy during percutaneous transluminal coronary angioplasty (PTCA). Tl-201 was injected at the last inflation of angioplastic balloon and occlusion was kept on for 60 sec. Planar images or SPECT were obtained immediately after PTCA. With this protocol, myocardial perfusion defects were observed during PTCA and fully redistributed 3 hours after Tl injection. Extent of ischemic lesions were almost same as that observed during exercise in two cases without collateral vessels...
December 1989: Kaku Igaku. the Japanese Journal of Nuclear Medicine
T Nakagawa, H Sugihara, S Inagaki, Y Kubota, N Inoue, A Azuma, K Shimoo, D Inoue, K Furukawa, J Asayama
To evaluate myocardial perfusion during transient coronary arterial occlusion, thallium-201 was administered intravenously during percutaneous transluminal coronary angioplasty (PTCA) in 12 patients with effort angina, and the resulting perfusion images were compared with those of exercise stress obtained before PTCA. Thallium-201 was injected at the last inflation of an angioplastic balloon and occlusion was maintained for 60 to 90 sec. Three projections of planar images were obtained immediately after PTCA, using a portable gamma camera in an angiography room...
March 1989: Journal of Cardiology
S Ogino, Y Yamamura, K Matsumoto, T Tanaka, K Shimoo, M Shigeta, S Kajiyama, T Higuchi, C Tanaka, S Sugino
No abstract text is available yet for this article.
August 1990: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
T Kuribayashi, K Shimoo, T Nakamura, K Hamaoka, M Nakagawa, Y Ibata, T Mizuta, T Komeda, A Nagaoka
We examined anatomically the hearts, lungs, and great vessels of 269 WKY/NCrj rats at three fetal and three neonatal stages. Severe pulmonary valve thickening was present in 16 and ventricular septal defects with overriding of the aorta in 15 of the 90 near-term fetuses and in 10 and nine, respectively, of the 79 neonates at 2-4 d of age. These abnormalities occurred together (tetralogy of Fallot) in seven of the near-term fetuses and in five of the neonates. A narrow pulmonary outflow tract was present in 55% of the fetuses and in 56% of the neonates...
November 1990: Pediatric Research
T Kuribayashi, K Shimoo, T Nakamura, H Taniwaki, K Hamaoka, M Nakagawa, Y Ibata, T Komeda, A Nagaoka
We examined anatomically the hearts of 198 WKY/NCrj rats of 20 litters. There were 51 rats with moderate to severe thickening of the pulmonary valve and 19 rats with a ventricular septal defect; the two lesions occurred together in 16 rats, in 15 of which there were overriding of the aorta, stenosis of the pulmonary outflow tract, and hypertrophy of the right ventricle, fulfilling the criteria for tetralogy of Fallot in man. The papillary muscle of the conus was absent in 65 rats. The heart was abnormally heavy in 18...
May 1990: Pediatric Research
T Nakamura, K Shimoo, T Kuribayashi, K Matsubara, M Shima, A Matsumuro, A Azuma, H Katsume, M Nakagawa
A high-frequency transducer was used to determine the optimal parameters for visualizing the heart in 40 normal Wistar, 15 SHR, and 10 aorta-banded rats. The rats were 5 to 30 weeks old and weighed between 105 and 705 grams. Two-dimensional and M-mode views of the ventricles, atria, valves, and great arteries were obtained by placing the transducer beneath the rats through the left or right parasternal window in either the prone or the right decubitus positions, respectively. Left ventricular (LV) mass was determined on the basis of a spheroid model; these values correlated well with the LV weight for both the Wistar rats (r = 0...
July 1991: Japanese Heart Journal
T Kuribayashi, M Taniwaki, K Nakamichi, T Nakamura, K Shimoo, M Nakagawa, A Nagaoka, T Komeda, Y Ibata
We examined 78 fetuses on d 21 of gestation (G21) and 83 neonates on d 2 after birth (A2), which were first generation offspring of WKY rats mated with normal Wistar rats (F1). In addition, we examined six groups of fetuses on d 19 of gestation (G19): 65 Wistar rats, 111 WKY rats, 85 F1, 100 F1 X F1, 92 F1 X Wistar, and 97 F1 X WKY progeny. In the F1 at G19, G21, and A2, there were abnormalities of the pulmonary valve, pulmonary outflow tract, architecture of muscle bundle, and pulmonary arterial branch, as well as hypoplastic ductus arteriosus and postnatal cardiac hypertrophy, similarly in males and females but at a lower incidence and to a lesser extent than in the WKY rats...
September 1991: Pediatric Research
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