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https://www.readbyqxmd.com/read/27899247/association-of-plasma-fetuin-a-levels-with-peripheral-arterial-disease-and-lower-extremity-arterial-calcification-in-subjects-with-type-2-diabetes-mellitus
#1
Ioanna Eleftheriadou, Pinelopi Grigoropoulou, Alexander Kokkinos, Iordanis Mourouzis, Despoina Perrea, Nicholas Katsilambros, Petros P Sfikakis, Nikolaos Tentolouris
AIMS: Fetuin-A is a hepatic glycoprotein that is involved in insulin resistance and atherosclerosis. Herein we examined the association of plasma fetuin-A levels with peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus (T2DM). MATERIAL AND METHODS: A total of 71 patients with T2DM and 57 non-diabetic individuals were recruited. Diagnosis of PAD was based on the absence of triphasic waveform at pedal arteries, while ankle-brachial index (ABI) was calculated...
November 12, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27897738/a-preventable-disaster
#2
Jennifer Trueland
When Ruth Miller looks at the latest figures on diabetes-related foot amputations, she admits that her heart sinks a little. As Poole NHS Foundation Trust's lead diabetes nurse, she knows the devastation the disease can wreak on people's feet. Yet this message does not seem to be getting through.
November 16, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27889202/analysis-of-the-elective-treatment-process-for-critical-limb-ischaemia-with-tissue-loss-diabetic-patients-require-rapid-revascularisation
#3
K Noronen, E Saarinen, A Albäck, M Venermo
OBJECTIVES: The number of elderly people is increasing; inevitably, the result will be more patients with critical limb ischaemia (CLI) in the future. Tissue loss in CLI is related to a high risk of major amputation. The aim of this study was to analyze the treatment process from referral to revascularisation, to discover possible delays and reasons behind them, and to distinguish patients benefitting the most from early revascularisation. METHODS: A retrospective analysis was performed of 394 consecutive patients with a combined 447 affected limbs, referred to the outpatient clinic during 2010-2011 for tissue loss of suspected ischaemic origin...
November 24, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27871769/-effect-of-mechanical-vibration-on-transcutaneous-oxygen-levels-in-the-feet-of-type-2-diabetes-mellitus-patients
#4
Gerardo Rodríguez Reyes, Lidia Núñez Carrera, Aldo Alessi Montero, Adriana Solís Vivanco, Ivett Quiñones Uriostegui, Alberto Isaac Pérez Sanpablo
BACKGROUND AND OBJECTIVE: Foot conditions in patients with diabetes mellitus (DM) are major causes of morbidity and disability. Whole body vibration may promote blood circulation in the lower limbs, hence facilitating perfusion and promoting the supply of nutrients and oxygen to comprised tissues. Transcutaneous oxygen levels (TcPO2)>40mmHg in cases of diabetic foot syndrome are associated with a good prognosis in the resolution of ulcers. The objective of this study was to determine whether whole body vibration favors some parameters of interest related to complications associated with the diabetic foot syndrome...
November 18, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27861361/a-quantitative-real-time-assessment-of-buerger-exercise-on-dorsal-foot-peripheral-skin-circulation-in-patients-with-diabetes-foot
#5
Chang-Cheng Chang, Men-Yen Chen, Jen-Hsiang Shen, Yen Bin Lin, Wen-Wei Hsu, Bor-Shyh Lin
Buerger exercise can improve the peripheral circulation of lower extremities. However, the evidence and a quantitative assessment of skin perfusion immediately after this exercise in patients with diabetes feet are still rare.We recruited 30 patients with unilateral or bilateral diabetic ulcerated feet in Chang Gung Memorial Hospital, Chia-Yi Branch, from October 2012 to December 2013. Real-time dorsal foot skin perfusion pressures (SPPs) before and after Buerger exercise were measured and analyzed. In addition, the severity of ischemia and the presence of ulcers before exercise were also stratified...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27827276/influence-of-beliefs-about-health-and-illness-on-self-care-and-care-seeking-in-foreign-born-people-with-diabetic-foot-ulcers-dissimilarities-related-to-origin
#6
K Hjelm, J Apelqvist
OBJECTIVE: To describe beliefs about health and illness among foreign-born people with diabetic foot ulcers that might affect self-reported self-care and health-care seeking and to study whether there are dissimilarities related to origin. METHOD: Qualitative descriptive study. Semi-structured interviews with people aged 38-86 years; 13 born in European and 13 in non-European countries (all except one in the Middle East). All resident in Sweden for 7-60 years (median: 18...
November 2, 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/27790114/bilateral-necrotizing-fasciitis-of-the-foot-associated-with-group-b-streptococcus
#7
Keitaro Fukuda, Misao Ryujin, Reiko Sakio, Satoshi Fukuzumi, Takanori Omae, Kazuhito Hayakawa
Necrotizing fasciitis (NF) is a severe bacterial infection involving fascia and subcutaneous tissue. It generally affects upper or lower extremities unilaterally, and there are few reports of bilateral-extremity NF. Here, we report a case of a 43-year-old male with type 1 diabetes who had NF on the left foot and subsequently developed NF on the other foot 1 week later. The patient survived with antimicrobial therapy and bilateral below-knee amputation. As group B streptococcus (GBS) was isolated by blood culture and culture of excised tissues of both feet, bilateral GBS NF of the foot was diagnosed...
September 2016: Case Reports in Dermatology
https://www.readbyqxmd.com/read/27783183/association-of-sudomotor-function-with-peripheral-artery-disease-in-type-2-diabetes
#8
Simran Chahal, Kanchan Vohra, Ashit Syngle
Peripheral artery disease (PAD) is the major risk factor for cardiovascular disease and lower extremity amputation in patients with diabetes. Autonomic neuropathy is a risk factor for cardiovascular-related morbidity and mortality. Sudomotor dysfunction is well established in type 2 diabetes mellitus (T2DM) and reflects small fibre neuropathy, cardiovascular autonomic neuropathy and peripheral sympathetic autonomic neuropathy. However, the relationship between sudomotor dysfunction and PAD remains unexplored...
October 25, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27751995/renal-transplantation-assessment-of-at-risk-diabetic-foot-and-recommendations-for-mitigation
#9
O P Prajapati, A K Verma, R K Sharma, M Sabaretnam
We conducted a prospective study (between November 2013 and January 2015) to identify "foot at risk" in the diabetic renal transplant patients at a Tertiary Care Hospital in India. Patients (151) were divided into three groups: diabetic transplant recipients (n = 42), new onset diabetes after transplantation (NODAT) (n = 59), and controls (nondiabetic renal transplant recipients) (n = 50). Foot neuropathy and vasculopathy were assessed by standard methods. Patients with "at risk" feet were given foot care advice...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27749777/utility-of-pet-ct-with-fluorine-18-fluorodeoxyglucose-labeled-autologous-leukocytes-for-diagnosing-diabetic-foot-osteomyelitis-in-patients-with-charcot-s-neuroarthropathy
#10
Ashu Rastogi, Anish Bhattacharya, Mahesh Prakash, Sarika Sharma, Bhagwant R Mittal, Niranjan Khandelwal, Anil Bhansali
OBJECTIVE: Diabetic foot osteomyelitis (DFO) is difficult to diagnose in the presence of Charcot's neuroarthropathy (CN) and bone biopsy is not always possible. We aimed to assess the efficacy of PET/computed tomography using F-fluoride (F-fluoride PET/CT) and fluorine-18-fluorodeoxyglucose-labeled autologous leukocytes (F-FDG-LL PET/CT) in comparison with contrast-enhanced MRI (CEMRI) for the detection of DFO. PATIENTS AND METHODS: Thirty-two patients with chronic CN and foot ulcer suspected of having DFO were prospectively evaluated...
October 4, 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27746370/capsaicin-8-patch-in-painful-diabetic-peripheral-neuropathy-a-randomized-double-blind-placebo-controlled-study
#11
David M Simpson, Jessica Robinson-Papp, Joanna Van, Malcolm Stoker, Hélène Jacobs, Robert J Snijder, Diederik S Schregardus, Stephen K Long, Bruno Lambourg, Nathaniel Katz
: This 12-week study evaluated the efficacy and safety of capsaicin 8% patch versus placebo patch in painful diabetic peripheral neuropathy (PDPN). Patients aged ≥18 years with PDPN were randomized (1:1) to one 30-minute treatment (capsaicin 8% patch or placebo patch) to painful areas of feet. Overall, 369 patients were randomized (capsaicin 8% patch, n=186; placebo patch, n=183). Percentage reduction in average daily pain score from baseline to between Weeks 2-8 (the primary endpoint) was statistically significant for capsaicin 8% patch versus placebo (-27...
October 13, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27712882/spatial-frequency-content-of-plantar-pressure-and-shear-profiles-for-diabetic-and-non-diabetic-subjects
#12
Visar Berki, Brian L Davis
How high does pressure and shear stress sensor resolution need to be in order to reliably measure the plantar pressure and shear profiles (PPSPs) under normal and diabetic feet? In this study, pressure and shear stress data were collected from 26 total diabetic and control subjects using new instrumentation that measures vertical and horizontal force vectors of the plantar contact surface during multiple instances in the gait cycle. The custom built shear-and-pressure-evaluating-camera-system (SPECS) performs simultaneous recordings of pressure and both components of the horizontal force vector (medio-lateral and antero-posterior) at distinctive regions under one׳s foot, at a spatial resolution for each sensor equal to 1...
September 21, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27697870/prevalence-discomfort-and-self-relief-behaviours-of-painful-diabetic-neuropathy-in-taiwan-a-cross-sectional-study
#13
Sui-Whi Jane, Ming-Shyan Lin, Wen-Nan Chiu, Randal D Beaton, Mei-Yen Chen
OBJECTIVES: To explore the prevalence, discomfort, and self-relief behaviours of painful diabetic neuropathy (PDN) among rural community residents with type 2 diabetes. DESIGN: A community-based, cross-sectional study. SETTING: This study was part of a longitudinal cohort study of a nurse-led health promotion programme for preventing foot ulceration in Chiayi County, Taiwan. PARTICIPANTS: Six hundred and twenty-eight community adults with type 2 diabetes participated in this study...
October 3, 2016: BMJ Open
https://www.readbyqxmd.com/read/27697131/clinical-management-of-acute-diabetic-charcot-foot-in-denmark
#14
Rasmus Bo Jansen, Ole Lander Svendsen, Klaus Kirketerp-Møller
INTRODUCTION: Charcot foot is a severe complication to diabetes mellitus and treatment involves several different clinical specialities. Our objective was to describe the current awareness, knowledge and treatment practices of Charcot foot among doctors who handle diabetic foot disorders. METHODS: This study is based on a questionnaire survey sent out to healthcare professionals, primarily doctors, working with diabetic foot ulcers and Charcot feet in the public sector of the Danish healthcare system...
October 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27695634/phenol-rich-compounds-sweet-gel-a-statistically-more-effective-antibiotic-than-cloxacillin-against-pseudomonas-aeruginosa
#15
Mehrab Dashtdar, Mohammad Reza Dashtdar, Babak Dashtdar, Gazala Afreen Khan, Karima Kardi
OBJECTIVES: The purpose of this study was to obtain a natural antibiotic from Phenol-rich compounds; for the dressing and the treatment of chronic wounds. METHODS: The Phenol-rich compound sweet gel was prepared by blending four natural herbal extracts, Acacia catechu (L.F.), Momia (Shilajit), Castanea sativa, and Ephedra sinica stapf, with combination of a sweet gel medium, including honey, maple saps, Phoenix dactylifera L. (date), pomegranate extract and Azadirachta indica gum as a stabilizer...
September 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/27692828/happy-feet-application-for-the-management-of-diabetic-foot-osteomyelitis
#16
S Fiquet, F Desbiez, I Tauveron, N Mrozek, M Vidal, O Lesens
OBJECTIVE: We aimed to develop and implement an application that could improve the management of patients presenting with diabetic foot osteomyelitis. PATIENTS AND METHODS: Physicians from the multidisciplinary diabetic foot infection team and a software engineer first assessed the needs required for the infection management and application. An experimental version was then designed and progressively improved. A final version was implemented in clinical practice in 2013 by the multidisciplinary diabetic foot infection team of our university hospital...
September 28, 2016: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/27684570/hyperbaric-oxygen-therapy-promotes-wound-repair-in-ischemic-and-hyperglycemic-conditions-increasing-tissue-perfusion-and-collagen-deposition
#17
Dominik André-Lévigne, Ali Modarressi, Rodrigue Pignel, Marie-Luce Bochaton-Piallat, Brigitte Pittet-Cuénod
The treatment of chronic wounds remains inconsistent and empirical. Hyperbaric oxygen therapy (HBOT) is a promising method to improve wound repair but there is still a lack of understanding of its mechanisms of action and its indications are not yet clearly defined. We studied the effects of HBOT in four different wound conditions by inflicting bilateral wounds on the dorsal aspect of the feet of nonischemic or ischemic limbs in normoglycemic or hyperglycemic rats. To create an ischemic condition, arterial resection was performed unilaterally...
September 29, 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27676850/podological-aspects-in-diabetes-a-comparative-study-between-insulin-dependent-diabetes-and-non-insulin-dependent-diabetes-through-a-series-of-154-cases
#18
Karima Belhaj, Soumia Meftah, Laila Mahir, Fatima Lmidmani, Abdellatif Elfatimi
OBJECTIVE: Diabetic foot includes all foot abnormalities in diabetics; they are secondary to several pathophysiological mechanisms. Few studies have compared the two types of diabetes for podiatric complications. The objective of this work is to make a comparative study of podiatry profile, clinical, optical and electronic podoscopique between insulin-dependent diabetes (IDDM) and non-insulin dependent (NIDDM). MATERIALS/PATIENTS AND METHODS: This is a prospective study over one year, including diabetic patients who have been made, an optical podocopique review and static and dynamic electronics...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27660061/small-fiber-neuropathy-in-children-two-case-reports-illustrating-the-importance-of-recognition
#19
Janneke G J Hoeijmakers, Catharina G Faber, Carien J Miedema, Ingemar S J Merkies, Johan S H Vles
Small fiber neuropathy (SFN) is a debilitating condition that often leads to pain and autonomic dysfunction. In the last few decades, SFN has been gaining more attention, particularly in adults. However, literature about SFN in children remains limited. The present article reports the cases of 2 adolescent girls diagnosed with SFN. The first patient (14 years of age) complained about painful itch and tingling in her legs, as well as dysautonomia symptoms for years. She also reported a red/purple-type discoloration of her legs aggravated by warmth and standing, compatible with erythromelalgia...
September 22, 2016: Pediatrics
https://www.readbyqxmd.com/read/27649399/foot-temperature-trends-in-normal-diabetic-and-neuropathic-foot-populations
#20
Azza Alalwee, Jonathan D LeSar, Mina Ghassemi, Eugene Cheng, Steven Stuto, Lawrence Osher, Scott Bastian, Vincent J Hetherington, Jill Kawalec
INTRODUCTION AND OBJECTIVES: Patients with underlying peripheral neuropathy are subject to changes in foot temperature. (1,2) Of the many forms of neuropathy that affect the lower extremity, the most notable are those types associated with diabetes. The aim of this study was to look for differences in temperatures between uncomplicated diabetic, diabetic neuropathic, and non-diabetic neuropathic feet. METHODS: The feet of 75 subjects were divided into 3 groups: 1) normal (n=50 feet), 2) diabetic (n=50 feet), and 3) neuropathic (n=49 feet)...
September 2016: Journal of the American Podiatric Medical Association
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