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https://www.readbyqxmd.com/read/28808444/association-of-sudoscan-values-with-vibration-perception-threshold-in-chinese-patients-with-type-2-diabetes-mellitus
#1
Xiaoming Zhu, Fei Mao, Siying Liu, Hangping Zheng, Bin Lu, Yiming Li
AIMS/INTRODUCTION: SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. MATERIALS AND METHODS: A total of 920 Chinese patients with T2DM were enrolled in the study. Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between CAN and VPT values...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28756345/gait-alterations-in-the-uae-population-with-and-without-diabetic-complications-using-both-traditional-and-entropy-measures
#2
Kinda Khalaf, Haitham M Al-Angari, Ahsan H Khandoker, Sungmun Lee, Wael Almahmeed, Habiba S Al Safar, Herbert F Jelinek
Diabetic foot, one of the most common and debilitating manifestations of type 2 diabetes mellitus (T2DM), is the leading cause of worldwide non-traumatic lower extremity amputations. Diabetics who are at risk of ulceration are currently mainly identified by a thorough clinical examination of the feet, which typically does not show clear symptoms during the early stages of disease progression. In this study, we used a non-linear dynamics tool, gait entropy (GaitEN), in addition to traditional linear gait analysis methods, to investigate gait alterations amongst diabetic patients with combinations of three types of T2DM related complications: retinopathy, diabetic peripheral neuropathy (DPN) and nephropathy...
July 21, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28687150/virtually-optimized-insoles-for-offloading-the-diabetic-foot-a-randomized-crossover-study
#3
S Telfer, J Woodburn, A Collier, P R Cavanagh
Integration of objective biomechanical measures of foot function into the design process for insoles has been shown to provide enhanced plantar tissue protection for individuals at-risk of plantar ulceration. The use of virtual simulations utilizing numerical modeling techniques offers a potential approach to further optimize these devices. In a patient population at-risk of foot ulceration, we aimed to compare the pressure offloading performance of insoles that were optimized via numerical simulation techniques against shape-based devices...
June 24, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28682724/does-everything-that-s-counted-count-value-of-inflammatory-markers-for-following-therapy-and-predicting-outcome-in-diabetic-foot-infection
#4
Eric Ong, Sumaya Farran, Michelle Salloum, Summer Gardner, Nicholas Giovinco, David G Armstrong, Kathryn R Matthias, David E Nix, Mayar Al Mohajer
To assess the severity of inflammation associated with diabetic foot infection (DFI), values of inflammatory markers such as white blood count (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and neutrophil to lymphocyte ratio (NLR) are often measured and tracked over time. It remains unclear if these markers can aid the clinician in the diagnosis and management of DFI, and ensure more rational use of antibiotics. Hospitalized adult patients (n = 379) with DFI were retrospectively assessed for abnormal inflammatory markers, correlation between values of inflammatory markers, and clinical diagnosis on initial admission and on last follow-up...
June 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28668579/a-candidate-imaging-marker-for-early-detection-of-charcot-neuroarthropathy
#5
Paul K Commean, Kirk E Smith, Charles F Hildebolt, Kathryn L Bohnert, David R Sinacore, Fred W Prior
Inflammation-mediated foot osteopenia may play a pivotal role in the etiogenesis, pathogenesis, and therapeutic outcomes in individuals with diabetes mellitus (DM), peripheral neuropathy (PN), and Charcot neuroarthropathy (CN). Our objective was to establish a volumetric quantitative computed tomography-derived foot bone measurement as a candidate prognostic imaging marker to identify individuals with DMPN who were at risk of developing CN. We studied 3 groups: 16 young controls (27 ± 5 years), 20 with DMPN (57 ± 11 years), and 20 with DMPN and CN (55 ± 9 years)...
June 28, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28661227/a-preliminary-study-of-patient-specific-mechanical-properties-of-diabetic-and-healthy-plantar-soft-tissue-from-gated-magnetic-resonance-imaging
#6
Evan D Williams, Michael J Stebbins, Peter R Cavanagh, David R Haynor, Baocheng Chu, Michael J Fassbind, Vara Isvilanonda, William R Ledoux
Foot loading rate, load magnitude, and the presence of diseases such as diabetes can all affect the mechanical properties of the plantar soft tissues of the human foot. The hydraulic plantar soft tissue reducer instrument was designed to gain insight into which variables are the most significant in determining these properties. It was used with gated magnetic resonance imaging to capture three-dimensional images of feet under dynamic loading conditions. Custom electronics controlled by LabVIEW software simultaneously recorded system pressure, which was then translated to applied force values based on calibration curves...
July 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28658333/bacterial-genus-is-a-risk-factor-for-major-amputation-in-patients-with-diabetic-foot
#7
Natália Anício Cardoso, Lígia DE Loiola Cisneiros, Carla Jorge Machado, Juliana Merlin Cenedezi, Ricardo Jayme Procópio, Túlio Pinho Navarro
Objective: to evaluate whether bacterial genus is a risk factor for major amputation in patients with diabetic foot and infected ulcer. Methods: we conducted a case-control, observational study of 189 patients with infected ulcers in diabetic feet admitted to the Vascular Surgery Service of the Risoleta Tolentino Neves Hospital, from January 2007 to December 2012. The bacteriological evaluation was performed in deep tissue cultures from the lesions and amputation was considered major when performed above the foot'smiddle tarsus...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28656153/the-relationship-between-cardiovascular-autonomic-dysfunction-and-ocular-abnormality-in-chinese-t2dm
#8
Dandan Wang, Baiyu Shen, Chunrong Wu, Yanyan Xue, Yanjun Liu
OBJECTIVE: This study aims to explore the relationship between autonomic nerve dysfunction-assessed by cardiovascular autonomic neuropathy risk score (CAN-RS)-and ocular abnormality in Chinese type 2 diabetes mellitus (T2DM). METHOD: This is a cross-sectional study. A total of 335 subjects with T2DM were enrolled. The state of visual acuity, the lens, the vitreous, and the fundus were tested by professional ophthalmic instruments. The electrochemical skin conductance (ESC) of the hands and feet was measured by SUDOSCAN, from which a cardiovascular autonomic neuropathy risk score (CAN-RS) was calculated...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28649285/introduction-of-the-diagene-study-clinical-characteristics-pathophysiology-and-determinants-of-vascular-complications-of-type-2-diabetes
#9
Thijs T W van Herpt, Roosmarijn F H Lemmers, Mandy van Hoek, Janneke G Langendonk, Ronald J Erdtsieck, Bert Bravenboer, Annelies Lucas, Monique T Mulder, Harm R Haak, Aloysius G Lieverse, Eric J G Sijbrands
BACKGROUND: Type 2 diabetes is a major healthcare problem. Glucose-, lipid-, and blood pressure-lowering strategies decrease the risk of micro- and macrovascular complications. However, a substantial residual risk remains. To unravel the etiology of type 2 diabetes and its complications, large-scale, well-phenotyped studies with prospective follow-up are needed. This is the goal of the DiaGene study. In this manuscript, we describe the design and baseline characteristics of the study...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28638999/osteopontin-and-clusterin-levels-in-type-2-diabetes-mellitus-differential-association-with-peripheral-autonomic-nerve-function
#10
Raelene E Maser, M James Lenhard, Ryan T Pohlig, P Babu Balagopal
Osteopontin (OPN) and clusterin are secreted glycoproteins potentially associated with nerve function. Sudomotor dysfunction is associated with the development of foot ulcerations. The purpose of this study was to investigate the potential relationship of OPN and clusterin with sudomotor function (i.e., autonomic nerves that control sweating) in participants with type 2 diabetes mellitus (T2DM). Sudomotor function was assessed using SUDOSCAN® which measures electrochemical skin conductance (ESC) of the hands and feet...
June 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28637356/-footsnap-a-new-mobile-application-for-standardizing-diabetic-foot-images
#11
Moi Hoon Yap, Katie E Chatwin, Choon-Ching Ng, Caroline A Abbott, Frank L Bowling, Satyan Rajbhandari, Andrew J M Boulton, Neil D Reeves
BACKGROUND: We describe the development of a new mobile app called "FootSnap," to standardize photographs of diabetic feet and test its reliability on different occasions and between different operators. METHODS: FootSnap was developed by a multidisciplinary team for use with the iPad. The plantar surface of 30 diabetic feet and 30 nondiabetic control feet were imaged using FootSnap on two separate occasions by two different operators. Reproducibility of foot images was determined using the Jaccard similarity index (JSI)...
June 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28627029/treatment-by-a-moisturizer-of-xerosis-and-cracks-of-the-feet-in-men-and-women-with-diabetes-a-randomized-double-blind-placebo-controlled-study
#12
H Gin, M Rorive, S Gautier, M Condomines, M Saint Aroman, E Garrigue
AIM: To evaluate a moisturizer containing urea, glycerine and petrolatum for healing deep open fissures on the feet of people with diabetes. If left untreated, open fissures, an entry point for bacteria, can lead to infection, ulceration and further complications. METHODS: This randomized, double-blind, multicentre study at 19 hospitals, general practices and diabetologists in France and Belgium included participants with diabetes and a deep open target fissure on their heel...
September 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28616080/pedobarography-as-a-clinical-tool-in-the-management-of-diabetic-feet-in-new-zealand-a-feasibility-study
#13
Jason K Gurney, Uwe G Kersting, Dieter Rosenbaum, Ajith Dissanayake, Steve York, Roger Grech, Anthony Ng, Bobbie Milne, James Stanley, Diana Sarfati
BACKGROUND: The peripheral complications of diabetes mellitus remain a significant risk to lower-limb morbidity. In New Zealand, risk of diabetes, comorbidity and lower-limb amputation are highly-differential between demographic groups, particularly ethnicity. There is growing and convincing evidence that the use of pedobarography - or plantar pressure measurement - can usefully inform diabetic foot care, particularly with respect to the prevention of re-ulceration among high-risk patients...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28598049/diabetes-drug-prescription-pattern-and-awareness-among-health-care-providers-in-sub-himalayan-region-of-india-a-population-based-study
#14
Jatinder Mokta, Kiran Mokta, Asha Ranjan, Ivan Joshi, Mahak Garg
BACKGROUND: To determine the pattern of diabetic drug prescription and awareness about diabetes among primary health providers in the rural areas of Himachal Pradesh situated in the western Himalayas at an elevation range from 350 meters (1,148ft) to 6900 meters (22,966ft) above sea level. METHODS AND MATERIAL: Study was conducted in 20 rural areas of Himachal Pradesh, located 50 to 400 Km from state capital, at 2200 to 10,000 feet altitude. Non-pregnant diabetic adults were surveyed through 31 diabetic camps...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28595477/positive-effects-of-plantar-vibration-training-for-the-treatment-of-diabetic-peripheral-neuropathy-a-pilot-study
#15
Katerina Stambolieva, Dorina Petrova, Mariya Irikeva
PURPOSE: To evaluate the effectiveness of 8-week low-frequency plantar vibration training on patients with sensorimotor diabetic peripheral neuropathy (DPN). PARTICIPANTS: Twelve patients took part in the investigation. RESULTS: An increase of the nerve conductive velocity of soral and peroneal nerves of feet, increased postural stability, and disappearance of the pain and tingling were observed. CONCLUSION: The obtained results provide evidence for beneficial effects of 8-week plantar vibration training in patients with DPN...
June 9, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28588112/the-hoorn-diabetes-care-system-dcs-cohort-a-prospective-cohort-of-persons-with-type-2-diabetes-treated-in-primary-care-in-the-netherlands
#16
Amber Awa van der Heijden, Simone P Rauh, Jacqueline M Dekker, Joline W Beulens, Petra Elders, Leen M 't Hart, Femke Rutters, Nienke van Leeuwen, Giel Nijpels
PURPOSE: People with type 2 diabetes (T2D) have a doubled morbidity and mortality risk compared with persons with normal glucose tolerance. Despite treatment, clinical targets for cardiovascular risk factors are not achieved. The Hoorn Diabetes Care System cohort (DCS) is a prospective cohort representing a comprehensive dataset on the natural course of T2D, with repeated clinical measures and outcomes. In this paper, we describe the design of the DCS cohort. PARTICIPANTS: The DCS consists of persons with T2D in primary care from the West-Friesland region of the Netherlands...
June 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28587646/trends-in-sex-differences-in-the-receipt-of-quality-of-care-indicators-among-adults-with-diabetes-united-states-2002-2011
#17
Joni S Williams, Kinfe G Bishu, Alessandra St Germain, Leonard E Egede
BACKGROUND: Evidence suggests disparities in quality of care (QoC) indicators based on sex exist in adults diagnosed with diabetes; however, this research is limited. Therefore, the objective of this research study was to assess differences in QOC indicators in a nationally representative sample of men and women with diabetes. METHODS: Cross-sectional study of 17,702 men and women (≥18 years of age) with diabetes from the 2002-2011 Medical Expenditure Panel Survey Household Component...
June 6, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28571697/effects-of-monochromatic-infrared-phototherapy-in-patients-with-diabetic-peripheral-neuropathy-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
REVIEW
Caroline Cabral Robinson, Patrícia Da Silva Klahr, Cinara Stein, Maicon Falavigna, Graciele Sbruzzi, Rodrigo Della Méa Plentz
BACKGROUND: Monochromatic infrared energy (MIRE) or phototherapy has been used to improve plantar sensitivity and pain in lower limbs of patients with diabetic sensorimotor peripheral neuropathy (DSPN), but the available primary results are inconsistent. OBJECTIVE: To review systematically the effects of MIRE on plantar sensitivity and neuropathic pain in patients with DSPN. METHODS: Medline, EMBASE, Cochrane CENTRAL, and Google Scholar were searched up to September 2016...
July 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28557064/quantitative-assessment-of-wound-healing-using-high-frequency-ultrasound-image-analysis
#19
H Mohafez, S A Ahmad, M Hadizadeh, S Moghimi, S A Roohi, M H Marhaban, M I Saripan, S Rampal
PURPOSE: We aimed to develop a method for quantitative assessment of wound healing in ulcerated diabetic feet. METHODS: High-frequency ultrasound (HFU) images of 30 wounds were acquired in a controlled environment on post-debridement days 7, 14, 21, and 28. Meaningful features portraying changes in structure and intensity of echoes during healing were extracted from the images, their relevance and discriminatory power being verified by analysis of variance. Relative analysis of tissue healing was conducted by developing a features-based healing function, optimised using the pattern-search method...
May 29, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28551927/-percutaneous-correction-of-forefoot-deformities-in-diabetic-patients-in-order-to-prevent-pressure-sores-technique-and-results-in-20-consecutive-patients
#20
Mustafa Yassin, Avraham Garti, Eyal Heller, Moshe Weissbrot, Dror Robinson
INTRODUCTION: Diabetes mellitus is a 21st century pandemic. Due to life-span prolongation combined with the increased rate of diabetes, a growing population of patients is afflicted with neuropathic foot deformities. Traditional operative repair of these deformities is associated with a high complication rate and relatively common infection incidence. In recent years, in order to prevent these complications, percutaneous deformity correction methods were developed. OBJECTIVES: Description of experience accumulated in treating 20 consecutive patients with diabetic neuropathic foot deformities treated in a percutaneous fashion...
April 2017: Harefuah
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