keyword
https://read.qxmd.com/read/38088343/leveraging-a-sturdy-norm-how-ethicists-really-argue
#21
JOURNAL ARTICLE
David DeGrazia
Rarely do everyday discussions of ethical issues invoke ethical theories. Even ethicists deploy ethical theories less frequently than one might expect. In my experience, the most powerful ethical arguments rarely appeal to an ethical theory. How is this possible? I contend that ethical argumentation can proceed successfully without invoking any ethical theory because the structure of good ethical argumentation involves leveraging a sturdy norm, where the norm is usually far more specific than a complete ethical theory...
December 13, 2023: Cambridge Quarterly of Healthcare Ethics: CQ
https://read.qxmd.com/read/38073573/care-of-the-older-person-and-the-value-of-human-dignity
#22
JOURNAL ARTICLE
Félix Pageau, Gaëlle Fiasse, Lennart Nordenfelt, Emilian Mihailov
As the world population is rapidly aging, stakeholders must address the care of the elderly with great concern. Also, loss of dignity is often associated with aging due to dementia, mobility problems and diminished functional autonomy. However, dignity is a polysemic term that is deemed useless by some ethicists. To counter this claim, we propose four concepts to define it better and make use accurately of this notion. These are human dignity, dignity of identity, dignities of excellence and attributed dignities...
December 11, 2023: Bioethics
https://read.qxmd.com/read/38023570/emerging-role-of-nanotechnology-in-treatment-of-non-alcoholic-fatty-liver-disease-nafld
#23
REVIEW
Atie Moghtadaie, Hamidreza Mahboobi, Somayeh Fatemizadeh, Mohammad Amjad Kamal
Non-alcoholic fatty liver disease (NAFLD) is a prevailing health challenge that requires urgent innovative interventions. This review explores the role of nanotechnology as a promising potential in the treatment of NAFLD. It delineates the limitations of the current management strategies for NAFLD and highlights the new nanotechnology-based treatments including nanoemulsions, liposomes, micelles, polymeric nanoparticles, nanogels, inorganic nanoparticles, and zinc oxide nanoparticles. Despite the optimism surrounding the nanotechnological approach, the review underscores the need to address the limitations such as technical challenges, potential toxicity, and ethical considerations that impede the practical application of nanotechnology in NAFLD management...
2023: EXCLI Journal
https://read.qxmd.com/read/38020312/human-infection-challenge-in-the-pandemic-era-and-beyond-hic-vac-annual-meeting-report-2022
#24
REVIEW
Megan V C Barnes, Anika Mandla, Emma Smith, Maija Maskuniitty, Peter J M Openshaw
HIC-Vac is an international network of researchers dedicated to developing human infection challenge studies to accelerate vaccine development against pathogens of high global impact. The HIC-Vac Annual Meeting (3rd and 4th November 2022) brought together stakeholders including researchers, ethicists, volunteers, policymakers, industry partners, and funders with a strong representation from low- and middle-income countries. The network enables sharing of research findings, especially in endemic regions. Discussions included pandemic preparedness and the role of human challenge to accelerate vaccine development during outbreak, with industry speakers emphasising the great utility of human challenge in vaccine development...
2023: Immunotherapy advances
https://read.qxmd.com/read/37996706/ethics-and-regulation-of-neuronal-optogenetics-in-the-european-union
#25
REVIEW
Timo Faltus, Johannes Freise, Carsten Fluck, Hans Zillmann
Neuronal optogenetics is a technique to control the activity of neurons with light. This is achieved by artificial expression of light-sensitive ion channels in the target cells. By optogenetic methods, cells that are naturally light-insensitive can be made photosensitive and addressable by illumination and precisely controllable in time and space. So far, optogenetics has primarily been a basic research tool to better understand the brain. However, initial studies are already investigating the possibility of using optogenetics in humans for future therapeutic approaches for neuronal based diseases such as Parkinson's disease, epilepsy, or to promote stroke recovery...
December 2023: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/37991735/using-patient-quotations-in-chart-notes-a-clinical-ethics-perspective
#26
JOURNAL ARTICLE
Olivia Schuman, Haven Gabrielle Romero
AbstractPer the OpenNotes directive of the 21st Century Cures Act implemented in 2021, patients and their legally recognized representatives must be able to access the electronic medical record in real time. This is an opportunity for clinical ethicists and other providers to reflect on their charting practices, particularly how and when they quote patients. Although using direct quotations is common because it seems to avoid misinterpretation, it may not always be appropriate. In this article, we discuss some of the risks and benefits of quoting in the context of OpenNotes and provide suggestions for how clinical ethicists can leverage their unique position to help mitigate some of these risks and promote more reflective charting practices among the teams they work with...
2023: Journal of Clinical Ethics
https://read.qxmd.com/read/37975085/off-label-prescription-developing-a-guideline-and-validating-an-instrument-to-measure-physicians-and-clinical-pharmacists-knowledge-and-attitudes-toward-off-label-medication-use
#27
JOURNAL ARTICLE
Pooneh Salari, Bagher Larijani, Farzaneh Zahedi, Mahshad Noroozi
PURPOSE: Off-label medications have been challenging in healthcare systems, and their significance is emphasized throughout pandemics. The study was designed to develop an ethics guideline for prescribing off-label medications and also aimed to develop a valid instrument for evaluating physicians' and clinical pharmacists' knowledge and attitudes regarding off-label medication use. METHODS: In 2021, the two-phase study was done. A gap analysis study and a review of relevant guidelines and peer-reviewed papers were conducted in the first phase...
December 2023: Journal of Diabetes and Metabolic Disorders
https://read.qxmd.com/read/37963306/drug-shortages-in-oncology-asco-clinical-guidance-for-alternative-treatments
#28
JOURNAL ARTICLE
Edgardo S Santos, Thomas K Oliver, Christina Lacchetti, Rachel Geisel, Lalan S Wilfong, Amanda N Fader, Cathy Eng
PURPOSE: To increase awareness, outline strategies, and offer clinical guidance on navigating the complexities of treatment planning amid antineoplastic drug shortages. METHODS: A multidisciplinary panel of oncologists, ethicists, and patient advocates was assembled to provide rapid clinical guidance to help providers navigate appropriate patient care in cases where rationing or alternative therapies must be considered. The groups of content experts developed general principles for resource allocation during shortages and clinical guidance on alternative therapies for specific disease sites...
November 14, 2023: JCO oncology practice
https://read.qxmd.com/read/37963131/past-imperfect-future-tense
#29
JOURNAL ARTICLE
Matthew K Wynia
How should the field of bioethics grapple with a history that includes ethicists who supported eugenics, scientific racism, and even Nazi medicine and also ethicists who created the salutary policy and practice responses to those heinous aspects of medical history? Learning humility from studying historical errors is one path to improvement; finding courage from studying historical strengths is another, but these can be in tension. This commentary lays out these paths and seeks to apply them both to a contemporary challenge facing the field: why hasn't bioethics been more at the forefront of efforts to address inequities in health and health care?...
September 2023: Hastings Center Report
https://read.qxmd.com/read/37962930/reimagining-thriving-ethics-programs-without-ethics-committees
#30
JOURNAL ARTICLE
Hilary Mabel, Joshua S Crites, Thomas V Cunningham, Jordan Potter
With the increasing professionalization of clinical ethics, some hospitals and health systems utilize both ethics committees and professional clinical ethicists to address their ethics needs. Drawing upon historical critiques of ethics committees and their own experiences, the authors argue that, in ethics programs with one or more professional clinical ethicists, ethics committees should be dissolved when they fail to meet minimum standards of effectiveness. The authors outline several criteria for assessing effectiveness, describe the benefits of a model that places primary responsibility for ethics work with professional clinical ethicists-the PCE-primary model , and offer suggestions for alternative ethics program structures that empower healthcare professionals to contribute to ethics work in ways more tailored to their strengths and skills while minimizing the shortcomings of ethics committees...
November 14, 2023: American Journal of Bioethics: AJOB
https://read.qxmd.com/read/37946729/pioneering-neurohackers-between-egocentric-human-enhancement-and-altruistic-sacrifice
#31
JOURNAL ARTICLE
Günter Seyfried, Sandra Youssef, Markus Schmidt
The growing field of neurotechnology (NT) is becoming more and more accessible in terms of reduced costs, increasing availability and reliability of materials, and ways to implant devices. As in other engineering fields such as bio-or information technology, there is a growing community of pioneering hackers who (self-)experiment with NT and develop novel applications. While most debates about NT, its goals and ethical ramifications are usually conducted by professionals in the field (neuroscientists, -engineers, -ethicists), little is known within these institutional frameworks about the motivations, goals and visions of neurohackers and how they view ethical ramifications of NT therapeutics vs...
2023: Frontiers in Neuroscience
https://read.qxmd.com/read/37946395/beyond-the-consult-question-nurse-ethicists-as-architects-of-moral-spaces
#32
JOURNAL ARTICLE
Ian D Wolfe
Nurse Ethicists bring a unique perspective to clinical ethics consultation. This perspective provides an appreciation of ethical tensions that will exist beyond the consult question into the moral space of patient care. These tensions exist even when an ethically preferable plan of action is identified. Ethically appropriate courses of action can still lead to moral dilemmas for others. The nurse ethicist provides a lens well suited to identify and respond to these dilemmas. The nurse-patient relationship is the ethical foundation of nursing practice and this relational ontology is well suited to addressing ethical dilemmas that exist prior to and beyond the initial consult question...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946394/nurse-ethicists-innovative-resource-or-ideological-aspiration
#33
JOURNAL ARTICLE
Megan-Jane Johnstone
In recent years, there have been growing calls for nurses to have a formal advanced practice role as nurse ethicists in hospital contexts. Initially proposed in the cultural context of the USA where nurse ethicists have long been recognised, the idea is being advocated in other judications outside of the USA such as the UK, Australia and elsewhere. Such calls are not without controversy, however. Underpinning this controversy are ongoing debates about the theoretical, methodological and political dimensions of clinical ethics support services generally, and more recently where nurses might 'fit' within such a service...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946393/perspectives-on-the-role-of-the-nurse-ethicist
#34
JOURNAL ARTICLE
Jenny Jones, Paul J Ford, Giles Birchley, Settimio Monteverde
This paper offers four contrasting perspectives on the role of the nurse ethicist from authors based in different areas of world, with different professional backgrounds and at different career stages. Each author raises questions about how to understand the role of the nurse ethicist. The first author reflects upon their career, the scope and purpose of their work, ultimately arguing that the distinction between 'nurse ethicist' and 'clinical ethicist' is largely irrelevant. The second author describes the impact and value that a nurse in an ethics role plays, highlighting the 'tacit knowledge' and 'lived experience' they bring to clinical ethics consultation...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946392/operationalizing-the-role-of-the-nurse-ethicist-more-than-a-job
#35
JOURNAL ARTICLE
Georgina Morley, Ellen M Robinson, Lucia D Wocial
The idea of a role in nursing that includes expertise in ethics has been around for more than 30 years. Whether or not one subscribes to the idea that nursing ethics is separate and distinct from bioethics, nursing practice has much to contribute to the ethical practice of healthcare, and with the strong grounding in ethics and aspiration for social justice considerations in nursing, there is no wonder that the specific role of the nurse ethicist has emerged. Nurse ethicists, expert in nursing practice and the application of ethical theories and concepts, are well positioned to guide nurses through complex ethical challenges...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946388/nursing-ethics-as-a-distinct-entity-within-bioethics-implications-for-clinical-ethics-practice
#36
JOURNAL ARTICLE
Bryan Pilkington, Maryanne Giuliante
The question of whether nursing ethics is a distinct entity within bioethics is an important and thought-provoking one. Though fundamental bioethical principles are appreciated and applied within the practice of nursing ethics, there exist distinct considerations which make nursing ethics a unique subfield of bioethics. In this article, we focus on the importance of relationships as a distinguishing feature of the foundation of nursing ethics, evidenced in its education, practice, and science. Next, we consider two objections to our claim of distinctiveness: first, that nursing ethics is merely an application of bioethical principles; second, that many bioethical subfields emphasize relationships...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946387/fostering-moral-resilience-through-moral-case-deliberation
#37
JOURNAL ARTICLE
Suzanne Metselaar, Bert Molewijk
Moral distress forms a major threat to the well-being of healthcare professionals, and is argued to negatively impact patient care. It is associated with emotions such as anger, frustration, guilt, and anxiety. In order to effectively deal with moral distress, the concept of moral resilience is introduced as the positive capacity of an individual to sustain or restore their integrity in response to moral adversity. Interventions are needed that foster moral resilience among healthcare professionals. Ethics consultation has been proposed as such an intervention...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946386/e-walks-bring-ethics-to-the-bedside-a-nurse-ethicist-s-reflections
#38
REVIEW
Brenda Barnum
The unique role of the nurse ethicist in the clinical setting is one meant to enhance the ethical capacity of nurses, and front-line healthcare providers. As a nurse ethicist, it is also my goal to enhance the ethical climate of each individual work area, patient care unit, and the broader institution by encouraging ethical conversations, navigating ethical dilemmas, and seeking creative solutions to minimize moral distress and burnout. To provide preventive ethics support and education, I began regularly visiting patient care areas for ethics rounds, which I affectionately named "E-walks" (for Ethics Walks)...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37946385/a-semantic-exploration-nurse-ethicist-medical-ethicist-or-clinical-ethicist-do-distinctions-matter
#39
JOURNAL ARTICLE
Pamela J Grace, Aimee Milliken
Since the 1960s, it has been recognized that "medical ethics," the area of inquiry about the obligations of practitioners of medicine, is inadequate for capturing and addressing the complexities associated with modern medicine, human health, and wellbeing. Subsequently, a new specialty emerged which involved scholars and professionals from a variety of disciplines who had an interest in healthcare ethics. The name adopted is variously biomedical ethics or bioethics. The practice of bioethics in clinical settings is clinical ethics and its primary aim is to resolve patient care issues and conflicts...
August 2023: Nursing Ethics
https://read.qxmd.com/read/37945336/exploring-the-potential-utility-of-ai-large-language-models-for-medical-ethics-an-expert-panel-evaluation-of-gpt-4
#40
JOURNAL ARTICLE
Michael Balas, Jordan Joseph Wadden, Philip C Hébert, Eric Mathison, Marika D Warren, Victoria Seavilleklein, Daniel Wyzynski, Alison Callahan, Sean A Crawford, Parnian Arjmand, Edsel B Ing
Integrating large language models (LLMs) like GPT-4 into medical ethics is a novel concept, and understanding the effectiveness of these models in aiding ethicists with decision-making can have significant implications for the healthcare sector. Thus, the objective of this study was to evaluate the performance of GPT-4 in responding to complex medical ethical vignettes and to gauge its utility and limitations for aiding medical ethicists. Using a mixed-methods, cross-sectional survey approach, a panel of six ethicists assessed LLM-generated responses to eight ethical vignettes...
November 9, 2023: Journal of Medical Ethics
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