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https://www.readbyqxmd.com/read/29143768/an-electronic-system-for-the-contactless-reading-of-ecg-signals
#1
Francesca Romana Parente, Marco Santonico, Alessandro Zompanti, Mario Benassai, Giuseppe Ferri, Arnaldo D'Amico, Giorgio Pennazza
The aim of this work is the development of a contactless capacitive sensory system for the detection of (Electrocardiographic) ECG-like signals. The acquisition approach is based on a capacitive coupling with the patient body performed by electrodes integrated in a front-end circuit. The proposed system is able to detect changes in the electric charge related to the heart activity. Due to the target signal weakness and to the presence of other undesired signals, suitable amplification stages and analogue filters are required...
October 28, 2017: Sensors
https://www.readbyqxmd.com/read/29134982/electrocardiographic-and-blood-pressure-measurements-in-captive-african-lions-panthera-leo-immobilized-with-xylazine-ketamine-combination
#2
T O Omóbòwálé, P I Otuh, O A Adejumobi, J O Abiola, T Adebiyi, B N Ogunro, A O Adeogun
Electrocardiographic and blood pressure measurements are extremely valuable diagnostic tools in the evaluationof the cardiovascular system of living animals. In this study, 6-lead electrocardiograms were recorded from five male captiveAfrican lions (Panthera leo). Also, blood pressure measurements were recorded and compared from three different sites;fore limb, hind limb and the tail, were recorded. Immobilization was done with a combination of Ketamine Hydrochloride(10mg/kg) and Xylazine (3mg/kg). Measurements were recorded as mean ± standard deviation...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29059302/office-and-home-blood-pressures-as-determinants-of-electrocardiographic-left-ventricular-hypertrophy-among-black-nigerians-compared-with-white-flemish
#3
Augustine N Odili, Lutgarde Thijs, Wen-Yi Yang, John O Ogedengbe, Maxwell M Nwegbu, Lotte Jacobs, Fang-Fei Wei, Ying-Mei Feng, Zhen-Yu Zhang, Tatiana Kuznetsova, Tim S Nawrot, Jan A Staessen
BACKGROUND: The association of electrocardiographic left ventricular hypertrophy (ECG-LVH) with blood pressure (BP) in Blacks living in sub-Saharan Africa remains poorly documented. METHODS: In 225 Black Nigerians and 729 White Flemish, we analyzed QRS voltages and voltage-duration products and 12 criteria diagnostic of ECG-LVH in relation to office BP (mean of 5 consecutive readings) and home BP (duplicate morning and evening readings averaged over 1 week). RESULTS: In multivariable analyses, QRS voltage and voltage-duration indexes were generally higher in Blacks than Whites...
November 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/29026885/emergency-department-point-of-care-ultrasonography-improves-time-to-pericardiocentesis-for-clinically-significant-effusions
#4
Evan Avraham Alpert, Uri Amit, Larisa Guranda, Rafea Mahagna, Shamai A Grossman, Ariel Bentancur
OBJECTIVE: Our objective was to determine the utility of point-of-care ultrasound (POCUS) to identify and guide treatment of tamponade or clinically significant pericardial effusions in the emergency department (ED). METHODS: This was a retrospective cohort study of non-trauma patients who were diagnosed with large pericardial effusions or tamponade by the ED physician using POCUS. The control group was composed of those patients later diagnosed on the medical wards or incidentally in the ED by other means such as a computed tomography...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28965185/safety-pharmacokinetic-and-pharmacodynamics-of-erdafitinib-a-pan-fibroblast-growth-factor-receptor-fgfr-tyrosine-kinase-inhibitor-in-patients-with-advanced-or-refractory-solid-tumors
#5
Tomohiro Nishina, Shunji Takahashi, Ryota Iwasawa, Hidehisa Noguchi, Masayuki Aoki, Toshihiko Doi
Introduction This phase 1, open-label, multicenter, single-arm, dose-escalation study aimed to evaluate safety, pharmacokinetics (PK), and pharmacodynamics of erdafitinib (JNJ-42756493), an oral selective pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, and to determine the recommended phase 2 dose in Japanese patients with advanced or refractory solid tumors. Methods Three to 6 patients were enrolled into sequentially escalating dose cohorts (erdafitinib 2, 4, or 6 mg) with a daily dosing schedule of 21-day cycles or a 7 days-on/7 days-off intermittent schedule (erdafitinib 10 mg or 12 mg) of 28-day cycles...
September 30, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28928069/comments-on-the-new-international-criteria-for-electrocardiographic-interpretation-in-athletes
#6
Luis Serratosa-Fernández, Domingo Pascual-Figal, María Dolores Masiá-Mondéjar, María Sanz-de la Garza, Zigor Madaria-Marijuan, Juan Ramón Gimeno-Blanes, Carmen Adamuz
Sudden cardiac death is the most common medical cause of death during the practice of sports. Several structural and electrical cardiac conditions are associated with sudden cardiac death in athletes, most of them showing abnormal findings on resting electrocardiogram (ECG). However, because of the similarity between some ECG findings associated with physiological adaptations to exercise training and those of certain cardiac conditions, ECG interpretation in athletes is often challenging. Other factors related to ECG findings are race, age, sex, sports discipline, training intensity, and athletic background...
November 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28880843/a-novel-dual-gating-approach-using-joint-inertial-sensors-implications-for-cardiac-pet-imaging
#7
Mojtaba Jafari Tadi, Jarmo Teuho, Eero Lehtonen, Antti Saraste, Mikko Pänkäälä, Tero Koivisto, Mika Teräs
Positron emission tomography (PET) is a non-invasive imaging technique which may be considered as the state of art for the examination of cardiac inflammation due to atherosclerosis. A fundamental limitation of PET is that cardiac and respiratory motions reduce the quality of the achieved images. Current approaches for motion compensation involve gating the PET data based on the timing of quiescent periods of cardiac and respiratory cycles. In this study, we present a novel gating method called microelectromechanical (MEMS) dual gating which relies on joint non-electrical sensors, i...
October 4, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28866666/the-cumulative-effects-of-the-myh7-v878a-and-cacna1c-a1594v-mutations-in-a-chinese-family-with-hypertrophic-cardiomyopathy
#8
Bo Wang, Rui-Qi Guo, Jing Wang, Fan Yang, Lei Zuo, Ying Liu, Hong Shao, Yan Ju, Chao Sun, Lei Xu, Yan-Min Zhang, Li-Feng Wang, Li-Wen Liu
AIMS: We investigated the pathogenesis of MYH7-V878A and CACNA1C-A1594V mutations in a Chinese family with hypertrophic cardiomyopathy. METHODS: Clinical, electrocardiographic (ECG), echocardiographic, and cardiac magnetic resonance (CMR) examinations of members of a Chinese family were followed by exon and boarding intron analyses of 96 genes in the proband using second-generation sequencing. We confirmed the mutations by bidirectional Sanger sequencing in the members and in 300 healthy controls...
September 2, 2017: Cardiology
https://www.readbyqxmd.com/read/28838369/computer-interpreted-electrocardiograms-benefits-and-limitations
#9
REVIEW
Jürg Schläpfer, Hein J Wellens
Computerized interpretation of the electrocardiogram (CIE) was introduced to improve the correct interpretation of the electrocardiogram (ECG), facilitating health care decision making and reducing costs. Worldwide, millions of ECGs are recorded annually, with the majority automatically analyzed, followed by an immediate interpretation. Limitations in the diagnostic accuracy of CIE were soon recognized and still persist, despite ongoing improvement in ECG algorithms. Unfortunately, inexperienced physicians ordering the ECG may fail to recognize interpretation mistakes and accept the automated diagnosis without criticism...
August 29, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28821351/screening-for-atrial-fibrillation-in-patients-%C3%A2-65-years-using-an-automatic-blood-pressure-monitor-in-a-skilled-nursing-facility
#10
MULTICENTER STUDY
Joseph Wiesel, Thomas J Salomone
Early detection of asymptomatic atrial fibrillation (AF) provides an opportunity to treat patients to reduce their risk of stroke. Long-term residents of skilled nursing facilities frequently have multiple risk factors for strokes due to AF and may benefit from screening for AF. Patients in a skilled nursing facility 65 years and older, without a history of AF and without a pacemaker or defibrillator, were evaluated using a Microlife WatchBP Home A automatic blood pressure monitor that can detect AF when set to a triple reading mode...
October 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28789718/cardiovascular-pre-participation-screening-in-young-athletes-recommendations-of-the-association-of-european-paediatric-cardiology
#11
Peter Fritsch, Robert Dalla Pozza, Doris Ehringer-Schetitska, Eero Jokinen, Vesna Herceg, Erzsebet Hidvegi, Renate Oberhoffer, Andreas Petropoulos
Sudden death in young competitive athletes can be avoided by implementation of pre-participation screening programmes. A screening programme should be performed only by trained physicians and should include the athlete's personal and family history, physical examination results, and the readings from a 12-lead-electrocardiogram. The athlete should undergo this screening programme every second year to detect progressive diseases. In addition, the programme should include detailed instructions to the athletes to pause training during infections in order to prevent sudden death due to myocarditis...
November 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28750576/smartphone-based-tele-electrocardiography-support-for-primary-care-physicians-reduces-the-pain-to-treatment-time-in-acute-coronary-syndrome
#12
Vivek Chauhan, P C Negi, Sujeet Raina, Sunil Raina, Mukul Bhatnagar, Rajesh Guleri, Vikrant Kanwar, Kumar S Pandey
Background The Himachal Pradesh state acute coronary syndrome registry recorded a median delay of 13 h between the time of onset of pain to the time of making the diagnosis and giving treatment for acute coronary syndrome. We conducted a pilot study on providing 24-h tele-electrocardiography (Tele-ECG) services in the district Kangra of Himachal Pradesh, with the aim to reduce the time taken for diagnosis of acute coronary syndrome. Methods The intervention group for the study included eight rural community health centres, each with one to three primary care physicians, who were all unskilled in electrocardiogram interpretation...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28721542/molecular-characterization-modeling-in-silico-analysis-of-equine-pituitary-gonadotropin-alpha-subunit-and-docking-interaction-studies-with-ganirelix
#13
Anuradha Bhardwaj, Varij Nayan, Parvati Sharma, Sanjay Kumar, Yash Pal, Jitender Singh
Equine pituitary gonadotropins (eLH, eFSH, eCG) are heterodimeric glycoprotein hormones with alpha (α) and beta (β) subunits. It is responsible for maintenance of pregnancy in mares during early gestation and fairly valuable for inducing superovulation in animals other than equines. The alpha subunit is common, while beta subunit is species-specific in all glycoprotein hormones. In the present investigation, molecular cloning and in silico characterization including homology modeling and molecular docking analysis of the equine chorionic gonadotropin (eCG) alpha subunit was carried out for gaining structural and functional insights into the eCG alpha subunit and its possible interaction with ganirelix, a gonadotropin-releasing hormone (GnRH) antagonist...
December 2016: In Silico Pharmacology
https://www.readbyqxmd.com/read/28667190/3-lead-electrocardiogram-is-more-reliable-than-pulse-oximetry-to-detect-bradycardia-during-stabilisation-at-birth-of-very-preterm-infants
#14
Beatriz Iglesias, Marí­a José Rodríguez, Esther Aleo, Enrique Criado, Jose Martínez-Orgado, Luis Arruza
OBJECTIVES: Current neonatal resuscitation guidelines suggest the use of ECG in the delivery room (DR) to assess heart rate (HR). However, reliability of ECG compared with pulse oximetry (PO) in a situation of bradycardia has not been specifically investigated. The objective of the present study was to compare HR monitoring using ECG or PO in a situation of bradycardia (HR <100 beats per minute (bpm)) during preterm stabilisation in the DR. STUDY DESIGN: Video recordings of resuscitations of infants <32 weeks of gestation were reviewed...
June 30, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28646403/routine-ct-angiography-to-detect-severe-coronary-artery-disease-prior-to-transcatheter-aortic-valve-replacement
#15
S Chava, G Gentchos, A Abernethy, B Leavitt, E Terrien, H L Dauerman
Patients undergoing TAVR undergo routine CT angiography (CTA) to assess aorto-iliac pathology and annular dimensions. While coronary CTA may exclude severe CAD in younger patients, its efficacy in defining CAD severity prior to TAVR may be limited. We retrospectively studied 50 consecutive patients undergoing both invasive coronary angiography (ICA) and routine pre-TAVR CTA. Severe CAD was defined as ≥50% stenosis by quantitative coronary angiography and compared to a blinded CTA visual estimation of ≥50% stenosis...
August 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28644157/ecg-case-of-the-month-chest-pain-and-ecg-abnormalities
#16
D Luke Glancy
A 27-year-old man was admitted to the coronary care unit because of chest pain and an electrocardiogram (ECG) read by the computer as an inferior infarct and left ventricular hypertrophy (Figure).
May 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28628659/wave-intensity-of-aortic-root-pressure-as-diagnostic-marker-of-left-ventricular-systolic-dysfunction
#17
Bernhard Hametner, Stephanie Parragh, Thomas Weber, Siegfried Wassertheurer
BACKGROUND: Systolic left ventricular function strongly influences the blood pressure waveform. Therefore, pressure-derived parameters might potentially be used as non-invasive, diagnostic markers of left ventricular impairment. The aim of this study was to investigate the performance of pressure-based parameters in combination with electrocardiography (ECG) for the detection of left ventricular systolic dysfunction defined as severely reduced ejection fraction (EF). METHODS AND RESULTS: Two populations, each comprising patients with reduced EF and pressure-matched controls, were included for the main analysis (51/102 patients) and model testing (44/88 patients)...
2017: PloS One
https://www.readbyqxmd.com/read/28607679/proper-electronic-order-linkage-of-electrocardiograms-at-a-large-children-s-hospital-improves-reporting-and-revenue
#18
David S Spar, Wayne A Mays, David S Cooper, Lucille Sullivan, Terra Hicks, Jeffrey B Anderson
Electrocardiograms (ECGs) are performed to determine an individual's cardiac rhythm. Approximately 25,000 ECGs are performed yearly throughout our hospital system. Historically only 68% of all ECGs were performed with the proper order linked to the electronic ECG reading system (MUSE). Failure to link the orders to the electronic reading system leads to problems in patient safety, reporting and hospital revenue. Our aim was to increase the percentage of linked ECG orders in MUSE compared to total ECGs performed from 68% to 95%...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28501559/fast-accurate-and-easy-to-teach-qt-interval-assessment-the-triplicate-concatenation-method
#19
Valentin Saqué, Martino Vaglio, Christian Funck-Brentano, Maya Kilani, Olivier Bourron, Agnès Hartemann, Fabio Badilini, Joe-Elie Salem
BACKGROUND: The gold standard method for assessing the QTcF (QT corrected for heart rate by Fridericia's cube root formula) interval is the "QTcF semiautomated triplicate averaging method" (TAM), which consists of measuring three QTcF values semiautomatically, for each 10-second sequence of a triplicate electrocardiogram set, and averaging them to get a global and unique QTcF value. Thus, TAM is time consuming. We have developed a new method, namely the "QTcF semiautomated triplicate concatenation method" (TCM), which consists of concatenating the three 10-second sequences of the triplicate electrocardiogram set as if they were a single 30-second electrocardiogram, and measuring QTcF only once for the triplicate electrocardiogram set...
August 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28484122/effects-of-propranolol-and-verapamil-on-changes-in-tq-and-st-segment-potentials-during-graded-coronary-flow-reduction-in-a-porcine-myocardial-ischemia-model
#20
Ichiro Watanabe, Leonard S Gettes
Acute myocardial ischemia causes TQ depression and ST elevation. However, the effects of cardioprotective drugs such as β-blockers and Ca(++)-antagonists on the extent of TQ depression, ST elevation, and myocardial ischemic injury are not fully understood.We created a carotid-coronary shunt in 30 pigs, and extracellular K(+) ([K(+)]e), TQ, and ST segments were recorded simultaneously with K(+)-selective plunge electrodes placed in the left anterior descending artery (LAD) distribution during graded LAD flow reduction before and after administration of propranolol or verapamil...
May 31, 2017: International Heart Journal
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