keyword
https://read.qxmd.com/read/38370934/quality-of-life-social-support-and-pathways-of-care-among-persons-with-psychiatric-disorders-a-cross-sectional-study
#21
JOURNAL ARTICLE
Lingam Ponnuchamy, Sachin S Kumar, Gobinda Majhi, Prabhu Venkataraman
BACKGROUND: Patients with psychiatric disorders have varied psychosocial realities embedded in the community context. Help-seeking behavior is extremely crucial in determining the prognosis and outcome of interventions. OBJECTIVES: (1) To assess the levels of quality of life, perceived social support, and decision to first seek help. (2) To assess the association of socio-demographic variables with these domains. MATERIALS AND METHODS: A cross-sectional descriptive survey with 100 psychiatric patients in a tertiary care setting employed three scales, namely WHOQOL-BREF, PSSS, and WHO Pathways Encounter form...
November 2023: Industrial Psychiatry Journal
https://read.qxmd.com/read/38359950/the-gp-s-role-in-supporting-women-with-anal-incontinence-after-childbirth-injury
#22
JOURNAL ARTICLE
Abi Eccles, Joanne Parsons, Debra Bick, Michael R B Keighley, Anna Clements, Julie Cornish, Sarah Embleton, Abigail McNiven, Kate Seers, Sarah Hillman
BACKGROUND: Obstetric anal sphincter injury is the most common cause of anal incontinence (AI) for women, which often has profound impacts on women's lives. GPs offer a first line of contact for many, but we know that very few women experiencing AI postnatally report discussing it with their GPs. DESIGN AND SETTING: Qualitative study investigating women's experiences with their GP and GPs' perspectives about providing such care. AIM: The study aims to identify key ways GPs can support women with AI due to childbirth injuries...
February 15, 2024: British Journal of General Practice
https://read.qxmd.com/read/38356407/young-people-s-pathways-to-a-specialist-suicide-prevention-service-and-the-influence-of-caregiver-prior-suicidality-and-mental-health-treatment
#23
JOURNAL ARTICLE
Zozan Onay, Anna Sidis, Laura Robinson, Frank P Deane
AIM: Timely help-seeking and pathways to care (PtC) have been linked to positive outcomes in suicidal adolescents. While the importance of formal contacts is recognized, caregivers also play a significant role in these pathways. Caregiver's familiarity with mental health issues may influence an adolescent's PtC. This study explores the relationship between a caregiver's prior suicidality and mental health treatment on their children's pathways to entering a specialist suicide prevention treatment program...
February 15, 2024: Early Intervention in Psychiatry
https://read.qxmd.com/read/38343118/-why-are-we-stuck-in-hospital-barriers-to-people-with-learning-disabilities-autistic-people-leaving-long-stay-hospital-a-mixed-methods-study
#24
JOURNAL ARTICLE
Jon Glasby, Robin Miller, Anne-Marie Glasby, Rebecca Ince, Frederick Konteh
BACKGROUND: Transforming care so that people with learning disabilities and/or autistic people can receive support at home rather than in hospital settings is a key priority, but progress has been slow. Despite significant national debate, little previous research has engaged directly with people in hospital, their families or front-line staff to understand the issues from their perspectives. OBJECTIVES: This research seeks to better understand the experiences of people with learning disabilities and/or autistic people in long-stay hospital settings, their families and front-line staff - using this knowledge to create practice guides and training materials to support new understandings and ways of working...
February 2024: Health Soc Care Deliv Res
https://read.qxmd.com/read/38335764/pre-onset-subthreshold-psychotic-symptoms-are-associated-with-differential-treatment-delays-before-a-first-episode-of-psychosis-initial-evidence-and-implications
#25
JOURNAL ARTICLE
S V McIlwaine, S Mughal, M Ferrari, R Rosengard, A Malla, S Iyer, M Lepage, R Joober, J L Shah
BACKGROUND: Help-seeking and treatment delays are increasingly critical areas of study in mental health services. The duration of untreated psychosis (DUP), or the time between illness onset and initiation of treatment, is a predictor of symptom remission and functioning for a first episode of psychosis (FEP). The World Health Organization recommends that specialized treatment for psychosis be initiated within the first three months of FEP onset. As a result, research has focused on factors that are associated with threshold-level DUP, while the experience of subthreshold psychotic symptoms (STPS) prior to a FEP may also complicate and present barriers to accessing care for young people...
February 8, 2024: Schizophrenia Research
https://read.qxmd.com/read/38317290/conceptual-framework-on-barriers-and-facilitators-to-implementing-perinatal-mental-health-care-and-treatment-for-women-the-matrix-evidence-synthesis
#26
Rebecca Webb, Elizabeth Ford, Judy Shakespeare, Abigail Easter, Fiona Alderdice, Jennifer Holly, Rose Coates, Sally Hogg, Helen Cheyne, Sarah McMullen, Simon Gilbody, Debra Salmon, Susan Ayers
BACKGROUND: Perinatal mental health difficulties can occur during pregnancy or after birth and mental illness is a leading cause of maternal death. It is therefore important to identify the barriers and facilitators to implementing and accessing perinatal mental health care. OBJECTIVES: Our research objective was to develop a conceptual framework of barriers and facilitators to perinatal mental health care (defined as identification, assessment, care and treatment) to inform perinatal mental health services...
January 2024: Health Soc Care Deliv Res
https://read.qxmd.com/read/38316704/a-systematic-review-on-the-qualitative-experiences-of-people-living-with-lung-cancer-in-rural-areas
#27
REVIEW
Nabilah Ali, David Nelson, Daisy McInnerney, Samantha L Quaife, Despina Laparidou, Peter Selby, Ros Kane, Sarah Civello, Dawn Skinner, Zara Pogson, Michael D Peake, Ava Harding-Bell, Samuel Cooke
PURPOSE: To synthesize the qualitative literature exploring the experiences of people living with lung cancer in rural areas. METHODS: Searches were performed in MEDLINE, CINAHL, and PsycINFO. Articles were screened independently by two reviewers against pre-determined eligibility criteria. Data were synthesized using Thomas and Harden's framework for the thematic synthesis of qualitative research. The CASP qualitative checklist was used for quality assessment and the review was reported in accordance with the ENTREQ and PRISMA checklists...
February 6, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38297500/-am-i-really-the-priority-here-help-seeking-experiences-of-university-students-who-self-harmed
#28
JOURNAL ARTICLE
Alice Tickell, Peter Fonagy, Katalin Hajdú, Sandra Obradović, Stephen Pilling
BACKGROUND: Self-harm is a significant problem in university students because of its association with emotional distress, physical harm, broader mental health issues and potential suicidality. Research suggests that fewer than half of students who have self-harmed seek professional help when at university. AIMS: This study aimed to explore the help-seeking journeys of university students who had engaged in self-harm, to identify perceived facilitators and barriers to securing both formal and informal support...
February 1, 2024: BJPsych Open
https://read.qxmd.com/read/38291429/microrna-expression-signature-as-a-biomarker-in-the-diagnosis-of-nodal-t-cell-lymphomas
#29
JOURNAL ARTICLE
Muhammad Sufyan Bin Masroni, Gracie Wee Ling Eng, Ah-Jung Jeon, Yuan Gao, He Cheng, Sai Mun Leong, Jit Kong Cheong, Susan Swee-Shan Hue, Soo Yong Tan
BACKGROUND: The diagnosis of T-cell lymphomas is typically established through a multiparameter approach that combines clinical, morphologic, immunophenotypic, and genetic features, utilizing a variety of histopathologic and molecular techniques. However, accurate diagnosis of such lymphomas and distinguishing them from reactive lymph nodes remains challenging due to their low prevalence and heterogeneous features, hence limiting the confidence of pathologists. We investigated the use of microRNA (miRNA) expression signatures as an adjunctive tool in the diagnosis and classification of T-cell lymphomas that involve lymph nodes...
January 30, 2024: Cancer Cell International
https://read.qxmd.com/read/38277194/challenges-and-implications-for-menopausal-health-and-help-seeking-behaviors-in-midlife-women-from-the-united-states-and-china-in-light-of-the-covid-19-pandemic-web-based-panel-surveys
#30
JOURNAL ARTICLE
Bobo Hi Po Lau, Catherine So Kum Tang, Eleanor Holroyd, William Chi Wai Wong
BACKGROUND: The global population of women of menopausal age is quickly increasing. The COVID-19 pandemic has led to an accelerated increase in the use of telehealth services, especially technological solutions targeting women's health. Understanding the factors behind midlife women's help-seeking behaviors amidst the pandemic will assist in the development of person-centered holistic telehealth solutions targeting menopausal and postreproductive health. OBJECTIVE: This study aimed to compare the factors underlying help-seeking for menopausal distress among midlife women in the United States and China...
January 26, 2024: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38250784/real-world-evaluation-of-the-feasibility-acceptability-and-safety-of-a-remote-self-management-parkinson-s-disease-care-pathway-a-healthcare-improvement-initiative
#31
JOURNAL ARTICLE
Angie A Kehagia, Sarah Chowienczyk, Michelle Helena van Velthoven, Emma King, Tracie North, Deb Shenton, Jane Abraham, Joseph Langley, Rebecca Partridge, Ursula Ankeny, Terry Gorst, Emma Edwards, Sue Whipps, Martha Batup, Jane Rideout, Mat Swabey, Jemma Inches, Sue Bentley, Georgina Gilbert, Camille Carroll
BACKGROUND: There is significant unmet need for effective and efficiently delivered care for people with Parkinson's disease (PwP). We undertook a service improvement initiative to co-develop and implement a new care pathway, Home Based Care (HBC), based on supported self-management, remote monitoring and the ability to trigger a healthcare contact when needed. OBJECTIVE: To evaluate feasibility, acceptability and safety of Home Based Care. METHODS: We evaluated data from the first 100 patients on HBC for 6 months...
2024: Journal of Parkinson's Disease
https://read.qxmd.com/read/38236274/developmental-pathways-of-the-family-bereavement-program-to-promote-growth-15-years-after-parental-death
#32
JOURNAL ARTICLE
Emily Fritzson, Na Zhang, Sharlene A Wolchik, Irwin N Sandler, Jenn-Yun Tein, Keith M Bellizzi
Although parental death increases the risks of negative developmental outcomes, some individuals report personal growth, an outcome that has received little attention. We tested a developmental cascade model of postloss growth in 244 parentally bereaved youth (ages 8-16 at baseline) from 156 families who participated in a randomized controlled trial of a family-based intervention, the Family Bereavement Program (FBP). Using five waves of data, the present study examined the prospective associations between the quality of parenting immediately following the FBP and postloss growth 6 and 15 years later, and whether these associations were mediated by changes in intra- and interpersonal factors (mediators) during the initial 11 months following the FBP...
January 18, 2024: Journal of Family Psychology: JFP
https://read.qxmd.com/read/38199599/lair1-mediated-resistance-of-hepatocellular-carcinoma-cells-to-t-cells-through-a-gsk-3%C3%AE-%C3%AE-catenin-myc-pd-l1-pathway
#33
JOURNAL ARTICLE
Banglun Pan, Xiaoling Ke, Jiacheng Qiu, Dongjie Ye, Zhu Zhang, Xiaoxia Zhang, Yue Luo, Yuxin Yao, Xiaoxuan Wu, Xiaoqian Wang, Nanhong Tang
BACKGROUND: An increasing number of studies have reported the involvement of oncogenes in the regulation of the immune system. LAIR1 is an immunosuppressive molecule and its role in immune-related diseases has been mainly reported. To date, it is unclear whether LAIR1 in tumor cells is involved in immune regulation. Therefore, the aim of this study was to investigate the role of LAIR1 in the immune microenvironment of hepatocellular carcinoma (HCC) to seek the novel therapeutic discoveries...
January 8, 2024: Cellular Signalling
https://read.qxmd.com/read/38199396/pathways-of-depressive-symptoms-to-self-harm-and-suicide-warning-signs-during-covid-19-pandemic-the-role-of-anxiety-and-related-distress-dysfunction-and-somatization
#34
JOURNAL ARTICLE
Silvia Morales Chainé, Germán Palafox, Rebeca Robles García, Paulina Arenas Landgrave, Alejandra López Montoya, Violeta Félix Romero, Mireya Atzala Imaz Gispert
BACKGROUND: Early in the COVID-19 pandemic, concern about widespread waves of depression and suicide emerged worldwide. Clarity on the relationship between mental health symptoms and warning signs of current self-harm or suicide thoughts and behaviors (ShSTB) in Mexican adults could be useful for designing effective public health policies and preventive strategies during health emergencies. OBJECTIVE: The present study uses a path model to explore the relationship between depressive symptoms, anxiety, and related distress, dysfunction, and somatization with ShSTB warning signs in Mexican adults during the COVID-19 pandemic...
January 8, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38169408/exploring-molecular-mechanisms-of-intra-articular-changes-in-osteonecrosis-of-femoral-head-using-dia-proteomics-and-bioinformatics
#35
JOURNAL ARTICLE
Gang Zhao, Yujie Liu, Yongjun Zheng, Mingyang An, Jia Zhang, Jing Zhang, Zhongli Li, Li Chunbao
PURPOSE: This study is aimed to delve into the crucial proteins associated with hormonal osteonecrosis of the femoral head (ONFH) and its intra-articular lesions through data-independent acquisition (DIA) proteomics and bioinformatics analysis. METHODS: We randomly selected samples from eligible ONFH patients and collected samples from the necrotic area of the femoral head and load-bearing cartilage. The control group comprised specimens from the same location in patients with femoral neck fractures...
January 3, 2024: Journal of Orthopaedic Surgery and Research
https://read.qxmd.com/read/38167770/diagnostic-test-utilization-management-strategies-as-an-opportunity-for-equitable-access-to-molecularly-informed-clinical-care
#36
JOURNAL ARTICLE
Helen X Hou, Annie Li, Julia C Thierauf, Jochen K Lennerz
BACKGROUND: Companion diagnostics are an essential component of oncology. Timing, cost, and adaptability to new drug/biomarker approvals represent challenges in assuring value-based care. Overcoming these challenges requires strategies for equitable access and efficient integration. METHODS: Based on prior laboratory improvements and payor policy implementations, we define equitable access in laboratory testing and conceptualized a framework for initiatives that optimize diagnostic performance...
January 3, 2024: Journal of Applied Laboratory Medicine
https://read.qxmd.com/read/38146705/connecting-to-community-a-social-identity-approach-to-neighborhood-mental-health
#37
JOURNAL ARTICLE
S Alexander Haslam, Polly Fong, Catherine Haslam, Tegan Cruwys
ACADEMIC ABSTRACT: Integrative theorizing is needed to advance our understanding of the relationship between where a person lives and their mental health. To this end, we introduce a social identity model that provides an integrated explanation of the ways in which social-psychological processes mediate and moderate the links between neighborhood and mental health. In developing this model, we first review existing models that are derived primarily from a resource-availability perspective informed by research in social epidemiology, health geography, and urban sociology...
December 26, 2023: Personality and Social Psychology Review
https://read.qxmd.com/read/38137145/an-insight-into-the-prospects-and-drawbacks-of-stem-cell-therapy-for-spinal-cord-injuries-ongoing-trials-and-future-directions
#38
REVIEW
Shahidul Islam Khan, Nazmin Ahmed, Kamrul Ahsan, Mahmud Abbasi, Rosario Maugeri, Dhiman Chowdhury, Lapo Bonosi, Lara Brunasso, Roberta Costanzo, Domenico Gerardo Iacopino, Giuseppe Emmanuele Umana, Bipin Chaurasia
Spinal cord injury (SCI) is a devastating neurological disorder that has a substantial detrimental impact on a person's quality of life. The estimated global incidence of SCI is 40 to 80 cases per million people and around 90% of cases are traumatic. Various etiologies can be recognized for SCI, and post-traumatic SCI represents the most common of these. Patients worldwide with SCI suffer from a persistent loss of motor and sensory function, which affects every aspect of their personal and social lives. Given the lack of effective treatments, many efforts have been made to seek a cure for this condition...
December 9, 2023: Brain Sciences
https://read.qxmd.com/read/38117006/help-seeker-satisfaction-with-diagnosis-and-treatment-of-tinnitus
#39
JOURNAL ARTICLE
Natalie Carmody, Michael Hunter, Robert H Eikelboom
OBJECTIVE: To examine help-seeker satisfaction with the first communication of a tinnitus diagnosis by a healthcare provider, whether help-seekers undertook treatment and how they rated this treatment. DESIGN: A survey design assessed tinnitus characteristics and distress, health status, help-seeking, diagnosis communication, treatment and patient satisfaction. STUDY SAMPLE: A self-selected cohort and a population-based cohort. RESULTS: Satisfaction scores were examined against demographic, clinical factors, and type of healthcare provider...
December 20, 2023: International Journal of Audiology
https://read.qxmd.com/read/38109688/using-dispositions-to-understand-otherwise-intractable-causal-pathways-to-psychological-problems-during-childhood-and-adolescence
#40
JOURNAL ARTICLE
Benjamin B Lahey
Studies of the genetic and environmental factors that make children more or less likely to develop distressing and impairing psychological problems, and studies of the psychobiological pathways through which these causal factors operate, have the goal of improving our understanding of the basic nature of psychological problems to develop better methods of prevention and treatment. For this reason, we have long had our eye on the prize of discovering the causes and psychobiological mechanisms underlying each dimension of psychological problems...
December 18, 2023: Journal of Clinical Child and Adolescent Psychology
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