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Help-seeking pathways

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https://www.readbyqxmd.com/read/29784759/of-what-use-is-connectomics-a-personal-perspective-on-the-drosophila-connectome
#1
REVIEW
Ian A Meinertzhagen
The brain is a network of neurons and its biological output is behaviour. This is an exciting age, with a growing acknowledgement that the comprehensive compilation of synaptic circuits densely reconstructed in the brains of model species is now both technologically feasible and a scientifically enabling possibility in neurobiology, much as 30 years ago genomics was in molecular biology and genetics. Implemented by huge advances in electron microscope technology, especially focused ion beam-scanning electron microscope (FIB-SEM) milling (see Glossary), image capture and alignment, and computer-aided reconstruction of neuron morphologies, enormous progress has been made in the last decade in the detailed knowledge of the actual synaptic circuits formed by real neurons, in various brain regions of the fly Drosophila It is useful to distinguish synaptic pathways that are major, with 100 or more presynaptic contacts, from those that are minor, with fewer than about 10; most neurites are both presynaptic and postsynaptic, and all synaptic sites have multiple postsynaptic dendrites...
May 20, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29783981/implementing-integrated-services-for-people-with-epilepsy-in-primary-care-in-ethiopia-a-qualitative-study
#2
Raquel Catalao, Tigist Eshetu, Ruth Tsigebrhan, Girmay Medhin, Abebaw Fekadu, Charlotte Hanlon
BACKGROUND: In order to tackle the considerable treatment gap for epilepsy in many low- and middle-income countries (LMICs), a task sharing model is recommended whereby care is integrated into primary health services. However, there are limited data on implementation and impact of such services in LMICs. Our study aimed to explore the perspectives of service users and caregivers on the accessibility, experience and perceived impact of epilepsy treatment received in a task-shared model in a rural district of Ethiopia...
May 21, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29774002/on-the-drive-specificity-of-freudian-drives-for-the-generation-of-seeking-activities-the-importance-of-the-underestimated-imperative-motor-factor
#3
Michael Kirsch, Wolfgang Mertens
Doubters of Freud's theory of drives frequently mentioned that his approach is outdated and therefore cannot be useful for solving current problems in patients with mental disorders. At present, many scientists believe that affects rather than drives are of utmost importance for the emotional life and the theoretical framework of affective neuroscience, developed by Panksepp, strongly underpinned this view. Panksepp evaluated seven so-called command systems and the SEEKING system is therein of central importance...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29720280/exposures-associated-with-infection-with-cryptosporidium-in-industrialised-countries-a-systematic-review-protocol
#4
Caoimhe McKerr, Sarah J O'Brien, Rachel M Chalmers, Roberto Vivancos, Robert M Christley
BACKGROUND: Cryptosporidium is a protozoan parasite of humans and other animals worldwide and is one of the greatest contributors to human diarrhoeal illness. Transmission can occur indirectly via contaminated food or water, or directly via contact with animals or other infected people. Risk exposures are often identified from outbreak investigations, but a subset of cases remains unexplained, and sources for sporadic disease and pathways to infection are still unclear. Given the few systematic syntheses of reported evidence in industrialised populations, the aim of this review is to consolidate the literature to describe exposures associated with human cryptosporidiosis in industrialised countries, specifically including the UK, and describe any differences between outbreak-associated and sporadic disease...
May 2, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29718795/dietary-flavanols-a-review-of-select-effects-on-vascular-function-blood-pressure-and-exercise-performance
#5
Yousef A Al-Dashti, Roberta R Holt, Charles L Stebbins, Carl L Keen, Robert M Hackman
An individual's diet affects numerous physiological functions and can play an important role in reducing the risk of cardiovascular disease. Epidemiological and clinical studies suggest that dietary flavanols can be an important modulator of vascular risk. Diets and plant extracts rich in flavanols have been reported to lower blood pressure, especially in prehypertensive and hypertensive individuals. Flavanols may act in part through signaling pathways that affect vascular function, nitric oxide availability, and the release of endothelial-derived relaxing and constricting factors...
May 2, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29706446/the-effect-of-implementation-of-an-early-detection-team-a-nationwide-register-based-study-of-characteristics-and-help-seeking-behavior-in-first-episode-schizophrenia-in-denmark
#6
Lene Halling Hastrup, Ulrik Helt Haahr, Julie Nordgaard, Erik Simonsen
BACKGROUND: In an effort to make people with signs of psychosis seek help as early as possible, Region Zealand launched in 2012 an early detection team project as the first and only in Denmark. The project consisted of a combination of easy access and an information campaign targeting the public. This nation-wide study examined characteristics and help-seeking behavior of patients with first-episode schizophrenia (FES) in the early detection region in comparison with other Danish regions...
April 26, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29696678/barriers-to-foot-care-in-patients-with-diabetes-as-identified-by-healthcare-professionals
#7
C J W Pankhurst, M E Edmonds
AIMS: To seek the views of healthcare professionals as to the barriers to foot care that they perceive as having an impact on clinical outcomes and contributing to the number of amputations. METHODS: The study involved healthcare professionals from the UK attending our 2015 and 2016 Masterclass diabetic foot conferences. Admission to these conferences was open to all members of the multidisciplinary spectrum who provide care of people with diabetes and foot problems...
April 26, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29658826/college-students-experiences-with-and-willingness-to-use-different-types-of-telemental-health-resources-do-gender-depression-anxiety-or-stress-levels-matter
#8
Tammy Toscos, Maria Carpenter, Michelle Drouin, Amelia Roebuck, Connie Kerrigan, Michael Mirro
OBJECTIVE: Telemental health (TMH) resources are plentiful; however, we know little about college students' opinions about such resources. We aimed to examine students' previous use of and willingness to use several types of TMH resources. PARTICIPANTS: Students (N = 662) from two U.S. Midwestern colleges participated. METHODS: Using an online survey in spring 2017, we measured students' depression, anxiety, stress, and suicidal thoughts, preferences for care options during distress, and use and interest in anonymous chats with trained nonprofessionals, online therapy, and self-help resources...
April 16, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29617390/myeloma-patient-accounts-of-their-pathways-to-diagnosis
#9
Debra A Howell, Ruth I Hart, Alexandra G Smith, Una Macleod, Russell Patmore, Gordon Cook, Eve Roman
BACKGROUND: Pathways to myeloma diagnosis can be prolonged, and are often preceded by multiple GP consultations and emergency presentation. This is the first qualitative study to examine events leading to diagnosis by asking patients about their experiences during this time. METHODS: Set within a UK population-based cohort, semi-structured interviews were conducted with 20 myeloma patients with varying characteristics and pathways, 12 of whom invited their relatives to take part...
2018: PloS One
https://www.readbyqxmd.com/read/29588369/phospholipid-subcellular-localization-and-dynamics
#10
Yanbo Yang, Minhyoung Lee, Gregory D Fairn
Membrane biology seeks to understand how lipids and proteins within bilayers assemble into large structures such as organelles and the plasma membrane. Historically, lipids were thought to merely provide structural support for bilayer formation and membrane protein function. Research has now revealed that phospholipid metabolism regulates nearly all cellular processes. Sophisticated techniques helped identify >10,000 lipid species, suggesting that lipids support many biological processes. Here, we highlight the synthesis of the most abundant glycerophospholipids classes and their distribution in organelles...
March 27, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29577840/the-relevance-of-victimization-experiences-for-predicting-the-development-of-threat-symptoms-during-adolescence-and-early-adulthood
#11
Thomas W Wojciechowski
The "threat" portion of the threat/control override symptom constellation is characterized by the belief by an individual that others seek to do them harm. There has yet to be an examination of the link between perceived threat symptomatology and the experience of victimization, despite the fact that both constructs are linked to the perpetration of violent behavior. Furthermore, there has yet to be research which examines the heterogeneity in developmental patterns of threat symptomatology. The present research utilized the Pathways to Desistance data to model the developmental heterogeneity in perceived threat symptomatology across adolescence and early adulthood using group-based trajectory modeling...
March 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29547642/-before-xpert-i-only-had-my-expertise-a-qualitative-study-on-the-utilization-and-effects-of-xpert-technology-among-pediatricians-in-4-indian-cities
#12
Andrew McDowell, Neeraj Raizada, Sunil D Khaparde, Raghuram Rao, Sanjay Sarin, Aakshi Kalra, Virender Singh Salhotra, Sreenivas Achuthan Nair, Catharina Boehme, Claudia M Denkinger
BACKGROUND: Diagnosing tuberculosis (TB) in children presents considerable challenges. Upfront testing on Xpert® MTB/RIF ('Xpert')-a rapid molecular assay with high sensitivity and specificity-for pediatric presumptive TB patients, as recommended by India's Revised National Tuberculosis Control Program (RNTCP), can pave the way for early TB diagnosis. As part of an ongoing project implemented by Foundation for Innovative New Diagnostics (FIND) dedicated to providing upfront free-of-cost (FOC) Xpert testing to children seeking care in the public and private sectors, a qualitative assessment was designed to understand how national guidelines on TB diagnosis and Xpert technology have been integrated into the pediatric TB care practices of different health providers...
2018: PloS One
https://www.readbyqxmd.com/read/29534556/strengthening-emergency-care-systems-to-mitigate-public-health-challenges-arising-from-influxes-of-individuals-with-different-socio-cultural-backgrounds-to-a-level-one-emergency-center-in-south-east-europe
#13
Michèle Twomey, Ana Šijački, Gert Krummrey, Tyson Welzel, Aristomenis K Exadaktylos, Marko Ercegovac
Emergency center visits are mostly unscheduled, undifferentiated, and unpredictable. A standardized triage process is an opportunity to obtain real-time data that paints a picture of the variation in acuity found in emergency centers. This is particularly pertinent as the influx of people seeking asylum or in transit mostly present with emergency care needs or first seek help at an emergency center. Triage not only reduces the risk of missing or losing a patient that may be deteriorating in the waiting room but also enables a time-critical response in the emergency care service provision...
March 12, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29518618/the-interplay-of-etiological-knowledge-and-mental-illness-stigma-on-healthcare-utilisation-in-the-community-a-structural-equation-model
#14
N Schnyder, C Michel, R Panczak, S Ochsenbein, B G Schimmelmann, F Schultze-Lutter
BACKGROUND: The stigma of mental illness, especially personal attitudes towards psychiatric patients and mental health help-seeking, is an important barrier in healthcare utilisation. These attitudes are not independent of each other and are also influenced by other factors, such as mental health literacy, especially the public's causal explanations for mental problems. We aimed to disentangle the interrelations between the different aspects of stigma and causal explanations with respect to their association with healthcare utilisation...
March 6, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29493414/understanding-pathways-to-care-of-individuals-entering-a-specialized-early-intervention-service-for-first-episode-psychosis
#15
Leopoldo J Cabassa, Sarah Piscitelli, Morgan Haselden, Rufina J Lee, Susan M Essock, Lisa B Dixon
OBJECTIVE: This study aimed to understand the pathways to care from the onset of a first episode of psychosis to entry into a specialized early intervention service (EIS) for individuals with nonaffective psychosis. METHODS: A sample of 20 individuals who participated in an EIS and ten of their family members were enrolled. Semistructured qualitative interviews were used to characterize participants' lives during the onset of psychosis and explore their help-seeking events from the onset of psychosis to entry into the EIS...
March 1, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29477071/gender-differences-in-temporal-relationships-between-gambling-urge-and-cognitions-in-treatment-seeking-adults
#16
Phoebe Dunsmuir, David Smith, A Kate Fairweather-Schmidt, Ben Riley, Malcolm Battersby
Many gambling-specific CBT programs seek to target either gambling-related urge or cognitions or both. However, little is known of the influence of one symptom type on another across time and whether these differ for men and women help-seeking problem gamblers. The aim of this study was threefold: to determine presence of measurement invariance for urge and cognition measures over time; to investigate the effect of baseline urge on end-of-treatment gambling-related cognitions - and the reciprocal relationship; and, identify whether these pathways differ across gender...
April 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29457677/the-contribution-of-a-negative-colorectal-screening-test-result-to-symptom-appraisal-and-help-seeking-behaviour-among-patients-subsequently-diagnosed-with-an-interval-colorectal-cancer
#17
Karen N Barnett, David Weller, Steve Smith, Robert Jc Steele, Peter Vedsted, Sheina Orbell, Sue M Moss, Jane W Melia, Julietta Patnick, Christine Campbell
BACKGROUND: Colorectal cancer (CRC) screening programmes using a guaiac faecal occult blood test (gFOBt) reduce CRC mortality. Interval cancers are diagnosed between screening rounds: reassurance from a negative gFOBt has the potential to influence the pathway to diagnosis of an interval colorectal cancer. METHODS: Twenty-six semi-structured face-to-face interviews were carried out in Scotland and England, with individuals diagnosed with an interval colorectal cancer following a negative gFOBt result...
February 19, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29390598/help-seeking-behaviour-and-its-impact-on-patients-attending-a-psychiatry-clinic-at-national-hospital-of-sri-lanka
#18
D M Gomez, C Gunarathna, S Gunarathna, K Gnanapragasam, Raveen Hanwella
Background: Mental illness contributes significantly to the global disease burden. There is great diversity in the manner in which mentally ill patients seek help as this is influenced by their beliefs and the opinion of the family-social support unit. The stigma associated with mental illness is a barrier to effective therapy in Sri Lanka where systematic public awareness programmes are minimal. Objective: To study the help-seeking behaviour and its impact on patients attending a psychiatry clinic of the National Hospital of Sri Lanka...
December 26, 2017: Ceylon Medical Journal
https://www.readbyqxmd.com/read/29357189/change-pathways-in-indigenous-and-nonindigenous-youth-suicide
#19
Deborah A Goebert, Fumiaki Hamagami, Earl S Hishinuma, Jane J Chung-Do, Jeanelle J Sugimoto-Matsuda
Multivariate dynamic relationships among suicide attempts, anxiety and/or depressive symptoms, hope, and help-seeking were examined across time in Native Hawaiian and non-Hawaiian adolescents, using data from a 5-year longitudinal cohort study (N = 7,317). The rate of suicide attempts decreased over time, but this reduction was significantly less among Native Hawaiian youth than their non-Hawaiian peers. There were also significant differences between groups in hope and help-seeking, with Native Hawaiian youth increasing help-seeking and decreasing hope to a greater degree...
January 22, 2018: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/29331600/a-real-world-study-on-the-genetic-cognitive-and-psychopathological-differences-of-obese-patients-clustered-according-to-eating-behaviours
#20
Mariarita Caroleo, Amedeo Primerano, Marianna Rania, Matteo Aloi, Valentina Pugliese, Fabio Magliocco, Gilda Fazia, Andrea Filippo, Flora Sinopoli, Marco Ricchio, Franco Arturi, Susana Jimenez-Murcia, Fernando Fernandez-Aranda, Pasquale De Fazio, Cristina Segura-Garcia
BACKGROUND: Considering that specific genetic profiles, psychopathological conditions and neurobiological systems underlie human behaviours, the phenotypic differentiation of obese patients according to eating behaviours should be investigated. The aim of this study was to classify obese patients according to their eating behaviours and to compare these clusters in regard to psychopathology, personality traits, neurocognitive patterns and genetic profiles. METHODS: A total of 201 obese outpatients seeking weight reduction treatment underwent a dietetic visit, psychological and psychiatric assessment and genotyping for SCL6A2 polymorphisms...
February 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
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