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Help-seeking pathways

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https://www.readbyqxmd.com/read/29331600/a-real-world-study-on-the-genetic-cognitive-and-psychopathological-differences-of-obese-patients-clustered-according-to-eating-behaviours
#1
Mariarita Caroleo, Amedeo Primerano, Marianna Rania, Matteo Aloi, Valentina Pugliese, Fabio Magliocco, Gilda Fazia, Andrea Filippo, Flora Sinopoli, Marco Ricchio, Franco Arturi, Susana Jimenez-Murcia, Fernando Fernandez-Aranda, Pasquale De Fazio, Cristina Segura-Garcia
BACKGROUND: Considering that specific genetic profiles, psychopathological conditions and neurobiological systems underlie human behaviours, the phenotypic differentiation of obese patients according to eating behaviours should be investigated. The aim of this study was to classify obese patients according to their eating behaviours and to compare these clusters in regard to psychopathology, personality traits, neurocognitive patterns and genetic profiles. METHODS: A total of 201 obese outpatients seeking weight reduction treatment underwent a dietetic visit, psychological and psychiatric assessment and genotyping for SCL6A2 polymorphisms...
December 14, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29326195/why-do-gps-leave-direct-patient-care-and-what-might-help-to-retain-them-a-qualitative-study-of-gps-in-south-west-england
#2
Anna Sansom, Rohini Terry, Emily Fletcher, Chris Salisbury, Linda Long, Suzanne H Richards, Alex Aylward, Jo Welsman, Laura Sims, John L Campbell, Sarah G Dean
OBJECTIVE: To identify factors influencing general practitioners' (GPs') decisions about whether or not to remain in direct patient care in general practice and what might help to retain them in that role. DESIGN: Qualitative, in-depth, individual interviews exploring factors related to GPs leaving, remaining in and returning to direct patient care. SETTING: South West England, UK. PARTICIPANTS: 41 GPs: 7 retired; 8 intending to take early retirement; 11 who were on or intending to take a career break; 9 aged under 50 years who had left or were intending to leave direct patient care and 6 who were not intending to leave or to take a career break...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29324652/food-addiction-and-binge-eating-lessons-learned-from-animal-models
#3
REVIEW
Marta G Novelle, Carlos Diéguez
The feeding process is required for basic life, influenced by environment cues and tightly regulated according to demands of the internal milieu by regulatory brain circuits. Although eating behaviour cannot be considered "addictive" under normal circumstances, people can become "addicted" to this behaviour, similarly to how some people are addicted to drugs. The symptoms, cravings and causes of "eating addiction" are remarkably similar to those experienced by drug addicts, and both drug-seeking behaviour as eating addiction share the same neural pathways...
January 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29297413/care-seeking-behaviors-for-maternal-and-newborn-illnesses-among-self-help-group-households-in-uttar-pradesh-india
#4
Kumudha Aruldas, Aastha Kant, P S Mohanan
BACKGROUND: India has made large strides in reducing maternal mortality ratio and neonatal mortality rate, yet care-seeking behavior for appropriate care is still a challenge. We conducted a qualitative study to understand the process of recognition and care-seeking for maternal and newborn illnesses in rural India where a health intervention through women's self-help groups (SHG) to improve maternal and newborn health behaviors is implemented by a non-governmental organization, the Rajiv Gandhi Mahila Vikas Pariyojana...
December 21, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29288895/online-nutrition-information-seeking-among-australian-primigravid-women
#5
Judith Maher, Catherine Robichaud, Elizabeth Swanepoel
BACKGROUND: optimal nutrition in pregnancy is crucial for short and long term health in both mother and child. While a large proportion of pregnant women utilise the internet for informational support during pregnancy, little is known about online practices relating to food and nutrition in pregnancy. METHODS: a qualitative study; Semi-structured interviews were undertaken with 16 primigravid women to explore their approaches and preferences when accessing and engaging with pregnancy-related nutrition information online...
December 14, 2017: Midwifery
https://www.readbyqxmd.com/read/29285407/designing-a-pain-management-protocol-for-craniotomy-a-narrative-review-and-consideration-of-promising-practices
#6
REVIEW
Susana Vacas, Barbara Van de Wiele
Background: Craniotomy is a relatively common surgical procedure with a high incidence of postoperative pain. Development of standardized pain management and enhanced recovery after surgery (ERAS) protocols are necessary and crucial to optimize outcomes and patient satisfaction and reduce health care costs. Methods: This work is based upon a literature search of published manuscripts (between 1996 and 2017) from Pubmed, Cochrane Central Register, and Google Scholar...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29273656/pathways-to-diagnosis-of-a-second-primary-cancer-protocol-for-a-mixed-methods-systematic-review
#7
Lovney Kanguru, Annemieke Bikker, Debbie Cavers, Karen Barnett, David H Brewster, David Weller, Christine Campbell
INTRODUCTION: As cancer survivors continue to live longer, the incidence of second primary cancers (SPCs) will also rise. Relatively little is understood about the diagnostic pathway for SPCs, how people appraise, interpret symptoms and seek help for a second different cancer and the experiences (including challenges) of healthcare providers relating to SPCs. This study aims to systematically appraise and synthesise the literature on the pathways to diagnosis of an SPC and the associated patient and healthcare provider experiences...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29250747/septo-hippocampal-interaction
#8
REVIEW
Christina Müller, Stefan Remy
The septo-hippocampal pathway adjusts CA1 network excitability to different behavioral states and is crucially involved in theta rhythmogenesis. In the medial septum, cholinergic, glutamatergic and GABAergic neurons form a highly interconnected local network. Neurons of these three classes project to glutamatergic pyramidal neurons and different subsets of GABAergic neurons in the hippocampal CA1 region. From there, GABAergic neurons project back to the medial septum and form a feedback loop between the two remote brain areas...
December 18, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/29232052/the-us-food-and-drug-administration-s-tentative-approval-process-and-the-global-fight-against-hiv
#9
Harinder Singh Chahal, Jeffrey S Murray, Martin Shimer, Peter Capella, Ryan Presto, Mary Lou Valdez, Peter G Lurie
INTRODUCTION: In 2004, the US government began to utilize the Food and Drug Administration's (USFDA) tentative approval process (tFDA) as a basis to determine which HIV drugs are appropriate to be purchased and used in resource-constrained settings. This process permits products that are not approved for marketing in the US, including medicines with active patents or marketing restrictions in the US, to be purchased and distributed in resource-constrained settings. Although the tFDA was originally intended to support the United States' President's Emergency Plan for AIDS Relief (PEPFAR), the USFDA list has become a cornerstone of international HIV programmes that support procurement of ARVs, such as the World Health Organization and the Global Fund to Fight AIDS, Tuberculosis, and Malaria...
December 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29163864/pathways-into-mental-health-care-for-uk-veterans-a-qualitative-study
#10
Harriet Mellotte, Dominic Murphy, Laura Rafferty, Neil Greenberg
Background: It is well established that veterans suffering from mental health difficulties under use mental health services. Objective: This study aimed to understand more about the barriers that prevent veterans from seeking professional help and the enablers that assist veterans in seeking professional help. It also aimed to explore potential mechanisms to improve veterans' help-seeking and pathways to care. Method: The study employed a qualitative design whereby 17 veterans who had recently attended specialist veteran mental health services took part in semi-structured interviews...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29126317/inflammation-friend-or-foe-for-animal-production
#11
Leon J Broom, Michael H Kogut
Inflammation is an essential immune response that seeks to contain microbial infection and repair damaged tissue. Increased pro-inflammatory mediators have been associated with enhanced resistance to a range of important poultry and pig pathogens. However, inflammation may also have undesirable consequences, including potentially exacerbating tissue damage and diverting nutrients away from productive purposes. The negative effects of inflammation have led to the active pursuit of anti-inflammatory feed additives and/or strategies...
November 4, 2017: Poultry Science
https://www.readbyqxmd.com/read/29117351/finding-the-missing-patients-with-tuberculosis-lessons-learned-from-patient-pathway-analyses-in-5-countries
#12
Christy Hanson, Mike Osberg, Jessie Brown, George Durham, Daniel P Chin
Background: Despite significant progress in diagnosis and treatment of tuberculosis over the past 2 decades, millions of patients with tuberculosis go unreported every year. The patient-pathway analysis (PPA) is designed to assess the alignment between tuberculosis care-seeking patterns and the availability of tuberculosis services. The PPA can help programs understand where they might find the missing patients with tuberculosis. Methods: This analysis aggregates and compares the PPAs from case studies in Kenya, Ethiopia, Indonesia, the Philippines, and Pakistan...
November 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29117349/using-patient-pathway-analysis-to-inform-a-differentiated-program-response-to-tuberculosis-the-case-of-kenya
#13
Enos Masini, Christy Hanson, Jeremiah Ogoro, Jessie Brown, Faith Ngari, Pia Mingkwan, Julia Makayova, Mike Osberg
Background: A recent tuberculosis prevalence survey in Kenya found that the country is home to nearly twice as many patients with tuberculosis as previously estimated. Kenya has prioritized identifying and treating the unnotified or missing cases of tuberculosis. This requires a better understanding of patient care seeking and system weaknesses. Methods: A patient-pathway analysis (PPA) was completed to assess the alignment between patient care seeking and the availability of tuberculosis diagnostic and treatment services at the national level and for all 47 counties at the subnational level in Kenya...
November 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29098119/process-review-for-development-of-quantitative-risk-analyses-for-transboundary-animal-disease-to-pathogen-free-territories
#14
REVIEW
Jonathan Miller, Ken Burton, Joe Fund, Adrian Self
Outbreaks of transboundary animal diseases (TADs) have the potential to cause significant detriment to animal, human, and environmental health; severe economic implications; and national security. Challenges concerning data sharing, model development, decision support, and disease emergence science have recently been promoted. These challenges and recommendations have been recognized and advocated in the disciplines intersecting with outbreak prediction and forecast modeling regarding infectious diseases. To advance the effective application of computation and risk communication, analytical products ought to follow a collaboratively agreed common plan for implementation...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/29096003/socioeconomic-differences-in-the-pathways-to-diagnosis-of-coronary-heart-disease-a-qualitative-study
#15
Sara Lena Schröder, Astrid Fink, Laura Hoffmann, Nadine Schumann, Olaf Martin, Stefan Frantz, Matthias Richter
Background: Socioeconomic inequalities in coronary heart disease (CHD)-related morbidity and mortality are well explored. However, less is known about the causes of inequalities in CHD treatment. In this qualitative study, we explored socioeconomic differences in the pathways to diagnosis of CHD. Methods: The data originated from 38 semi-structured interviews with older CHD patients, aged 59-80 years, conducted at the university hospital in Halle, Germany, between November 2014 and April 2015...
October 31, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29038343/beliefs-regarding-development-and-early-intervention-among-low-income-african-american-and-hispanic-mothers
#16
Dawn M Magnusson, Cynthia S Minkovitz, Karen A Kuhlthau, Tania M Caballero, Kamila B Mistry
OBJECTIVES: Understand the role of health beliefs in shaping maternal decisions regarding help-seeking for children with developmental delay (DD) and explore differences between African American and Hispanic mothers. METHODS: Open-ended, semistructured interviews were conducted with African American and Hispanic mothers of children aged 0 to 36 months with DD. Interviews were recorded, transcribed, and analyzed by using inductive content analysis. RESULTS: Mothers (n = 22) were African American (36%) or Hispanic (64%), 25 to 34 years old (64%), had less than a high school education (59%), and had children receiving public insurance (95%)...
November 2017: Pediatrics
https://www.readbyqxmd.com/read/29034701/urological-issues-following-gender-reassignment-surgery
#17
Iffy Middleton, Fiona Ann Holden
It has been estimated that 0.2% of the UK population identifies as transgender. For those who seek gender reassignment, the pathway can involve the expertise of multiple disciplines, including primary care, psychology, endocrinology and speech and language therapy. A small but significant number of the transgender population will also elect to undergo gender-affirming genital surgery in order to achieve gender congruence. In the UK, very few specialist centres provide genital gender-affirming surgery for trans-men and women...
October 12, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29019048/parental-action-and-referral-patterns-in-spatial-clusters-of-childhood-autism-spectrum-disorder
#18
David Schelly, Patricia Jiménez González, Pedro J Solís
Sociodemographic factors have long been associated with disparities in autism spectrum disorder (ASD) diagnosis. Studies that identified spatial clustering of cases have suggested the importance of information about ASD moving through social networks of parents. Yet there is no direct evidence of this mechanism. This study explores the help-seeking behaviors and referral pathways of parents of diagnosed children in Costa Rica, one of two countries in which spatial clusters of cases have been identified. We interviewed the parents of 54 diagnosed children and focused on social network connections that influenced parents' help seeking and referral pathways that led to assessment...
October 10, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29017319/a-prototype-for-modular-cell-engineering
#19
Brandon Wilbanks, Donovan Layton, Sergio Garcia, Cong Trinh
When aiming to produce a target chemical at high yield, titer, and productivity, various combinations of genetic parts available to build the target pathway can generate a large number of strains for characterization. This engineering approach will become increasingly laborious and expensive when seeking to develop desirable strains for optimal production of a large space of biochemicals due to extensive screening. Our recent theoretical development of modular cell (MODCELL) design principles can offer a promising solution for rapid generation of optimal strains by coupling a modular cell and exchangeable production modules in a plug-and-play fashion...
October 10, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28975109/phytotherapy-of-nephrotoxicity-induced-by-cancer-drugs-an-updated-review
#20
REVIEW
Saeid Heidari-Soreshjani, Majid Asadi-Samani, Qian Yang, Ali Saeedi-Boroujeni
CONTEXT: Kidney is one of the vital organs maintaining homeostasis of body and thus dysfunction of kidney affects quality of life and health severely. Anticancer drugs, particularly chemotherapeutic agents, cause high toxicity leading kidney dysfunction and irreparable kidney injury. Therefore, attention has recently been paid to seeking out alternatives such as nature-based drugs that are effective but less toxic. In this regard, this systematic review article is to report and introduce the most important medicinal plants and their derivatives that are used to reduce anticancer drug-induced nephrotoxicity...
July 2017: Journal of Nephropathology
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