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https://www.readbyqxmd.com/read/27932010/bottleneck-analysis-approach-to-accelerate-newborn-care-services-in-two-regions-in-ghana-implications-for-national-newborn-care
#1
A E Yawson, J K Awoonor-Williams, I Sagoe-Moses, P K Aboagye, A O Yawson, L K Senaya, G Bonsu, J B Eleeza, E E A Agongo, H K Banskota
OBJECTIVE: The aim of this work is to describe application of a data-driven approach (bottleneck analysis [BNA] approach process) to accelerate newborn care services in two regions and what effect it had on national-level newborn care interventions in Ghana. STUDY DESIGN: A mixed-method approach was used for the study. The BNA tool generated quantitative data and group discussions provided phenomenological explanations to identified service gaps. METHODS: Regional newborn care health service assessments were conducted in November 2013 through desk reviews, field and health facility visits and coaching/mentorship...
December 2016: Public Health
https://www.readbyqxmd.com/read/27922344/predictors-of-mortality-in-a-paediatric-intensive-care-unit-in-kigali-rwanda
#2
Rosine Nyirasafari, Mark H Corden, Angélique Charlie Karambizi, Jean Claude Kabayiza, Jean Damascene Makuza, Rex Wong, Michael F Canarie
BACKGROUND: The enormous burden of critical illness in resource-limited settings has led to a growing interest in paediatric critical care in these regions. However, published data on the practice of critical care and patient outcomes in these settings are scant. OBJECTIVE: This study sought to identify risk factors associated with mortality in the newly established Paediatric Intensive Care Unit (PICU) at Kigali University Teaching Hospital (KUTH) in Rwanda and test the predictive ability of a newly devised mortality risk score, the modified PRISM (MP) score...
December 6, 2016: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/27919151/-a-systematic-review-of-epidemiological-cohort-studies-based-on-the-italian-medical-birth-register-is-it-time-to-think-of-a-multicentric-birth-cohort
#3
REVIEW
Cristina Canova, Gisella Pitter, Patrizia Schifano
INTRODUCTION: birth cohorts are a necessary tool for the study of the effects of exposures which can occur during pregnancy and early life on the development and health status in paediatric and adult life. The Italian Medical Birth Register (CeDAP), linked with other health administrative data, allows to build population based births cohorts to be followed over time. OBJECTIVES: to sistematically review all published scientific papers using data extracted from the (CeDAP) in order to give a picture of their current use for epidemiological aims; to describe advantages and limits of these data and possible future developments for epidemiological purposes...
November 2016: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/27914683/paediatric-cutaneous-adnexal-tumours-a-study-of-559-cases
#4
Amanda M Ireland, Nathan T Harvey, Bligh D Berry, Benjamin A Wood
Cutaneous adnexal tumours encompass a wide group of lesions with apocrine, eccrine, follicular, sebaceous and mixed differentiation. The large majority are benign and represent sporadic lesions, though malignant forms are occasionally encountered and some cases develop in the setting of inherited tumour syndromes. Accurate histological classification can be difficult as there are numerous histological appearances, many of which are individually uncommon, and complex, overlapping and historically variable nomenclature is typical...
November 30, 2016: Pathology
https://www.readbyqxmd.com/read/27913837/hospitalizations-due-to-preventable-adverse-reactions-a-systematic-review
#5
REVIEW
Nidhi S Patel, Tejas K Patel, Parvati B Patel, Viren N Naik, C B Tripathi
PURPOSE: The study aimed to measure the percentage of preventable adverse drug reactions that lead to the hospitalization (PADRAd) and to explore the heterogeneity in its estimation through subgroup analysis of study characteristics. METHODS: Two investigators independently searched in electronic databases and related bibliography for prospective studies involving PADRAd. We excluded studies investigating medication errors and spontaneous and retrospective reporting...
December 2, 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27882508/regional-early-development-and-eruption-of-permanent-teeth-case-report
#6
A M Al Mullahi, A Bakathir, S Al Jahdhami
BACKGROUND: Early development and eruption of permanent teeth are rarely reported in scientific literature. Early eruption of permanent teeth has been reported to occur due to local factors such as trauma or dental abscesses in primary teeth, and in systemic conditions. Congenital diffuse infiltrating facial lipomatosis (CDIFL) is a rare condition that belongs to a group of lipomatosis tumours. In this disorder, the mature adipocytes invade adjacent soft and hard tissues in the facial region...
November 23, 2016: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27882295/neuroanatomical-correlates-of-childhood-apraxia-of-speech-a-connectomic-approach
#7
Simona Fiori, Andrea Guzzetta, Jhimli Mitra, Kerstin Pannek, Rosa Pasquariello, Paola Cipriani, Michela Tosetti, Giovanni Cioni, Stephen E Rose, Anna Chilosi
Childhood apraxia of speech (CAS) is a paediatric speech sound disorder in which precision and consistency of speech movements are impaired. Most children with idiopathic CAS have normal structural brain MRI. We hypothesize that children with CAS have altered structural connectivity in speech/language networks compared to controls and that these altered connections are related to functional speech/language measures. Whole brain probabilistic tractography, using constrained spherical deconvolution, was performed for connectome generation in 17 children with CAS and 10 age-matched controls...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27878130/an-unusual-case-of-transorificial-abdomino-thoracic-impalement-injury-in-a-child
#8
Hemanshi Shah, Charu Tiwari, Shalika Jayaswal, Keshav Murthy
Impalement injuries are rare in the paediatric age group. Still rarer are injuries which traverse multiple body cavities. Such injuries require multispecialty management at a tertiary care centre. We describe a case of an accidental impalement injury in a 12-year-old boy after a fall from height. The rod was seen passing through the right lung in the paracardiac region, piercing the diaphragm and segment IV of the liver and then coursing anterior to the inferior vena cava in the midline. It was seen passing through the small bowel at multiple places and then coursing behind the bladder, entering the rectum and anal canal...
October 2016: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27865727/-epidemiology-of-patients-hospitalised-due-to-bronchiolitis-in-the-south-of-europe-analysis-of-the-epidemics-2010-2015
#9
José Miguel Ramos-Fernández, Eva Pedrero-Segura, Mario Gutiérrez-Bedmar, Beatriz Delgado-Martín, Ana María Cordón-Martínez, David Moreno-Pérez, Antonio Urda-Cardona
INTRODUCTION: The renewal of clinical practice guidelines on acute bronchiolitis (AB) requires the re-assessment of the consequences of their implementation. An update is presented on the main clinical and epidemiological variables in patients hospitalised due to AB in Southern Europe and an analysis made of the causes associated with longer hospital stay. PATIENTS AND METHOD: A retrospective study was conducted on patients admitted to hospital due to AB during 5 epidemics (2010-2015), with an analysis of the major clinical and epidemiological variables...
November 16, 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/27865381/the-impact-of-bacille-calmette-gu%C3%A3-rin-shortage-on-immunisation-practice-and-policies-in-europe-a-paediatric-tuberculosis-network-european-trials-group-ptbnet-survey
#10
Antti Kontturi, Begoña Santiago, Marc Tebruegge, Ulrich von Both, Eeva Salo, Nicole Ritz
BACKGROUND: Recent reports indicate an ongoing BCG shortage that may influence immunisation practice. This study aimed to determine current availability of BCG vaccine across Europe, and implications on immunisation practices and policies in Europe. METHODS: Web-based survey among Paediatric Tuberculosis Network European Trials Group (ptbnet) members, between May and October 2015. RESULTS: Twenty individuals from 13 European countries participated...
December 2016: Tuberculosis
https://www.readbyqxmd.com/read/27832748/invasive-mucormycosis-in-children-an-epidemiologic-study-in-european-and-non-european-countries-based-on-two-registries
#11
Zoi Dorothea Pana, Danila Seidel, Anna Skiada, Andreas H Groll, Georgios Petrikkos, Oliver A Cornely, Emmanuel Roilides
BACKGROUND: Mucormycosis has emerged as a rare but frequently fatal invasive fungal disease. Current knowledge on paediatric mucormycosis is based on case reports and small series reported over several decades. Contemporary data on a large cohort of patients is lacking. METHODS: Two large international registries (Zygomyco.net and FungiScope™) were searched for mucormycosis cases in ≤19 year-old patients. Cases enrolled between 2005 and 2014 were extracted, and dual entries in the two databases merged...
November 10, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27832416/slow-continuous-enzyme-replacement-via-spinal-csf-in-dogs-with-the-paediatric-onset-neurodegenerative-disease-mps-iiia
#12
Barbara King, Neil R Marshall, Sofia Hassiotis, Paul J Trim, Justin Tucker, Kathryn Hattersley, Marten F Snel, Robert D Jolly, John J Hopwood, Kim M Hemsley
Intra-cerebrospinal fluid (CSF) injection of recombinant human lysosomal enzyme is a potential treatment strategy for several neurodegenerative lysosomal storage disorders including Sanfilippo syndrome (Mucopolysaccharidosis type IIIA; MPS IIIA). Here we have utilised the MPS IIIA Huntaway dog model to compare the effectiveness of the repeated intermittent bolus injection strategy being used in the trials with an alternate approach; slow, continual infusion of replacement enzyme (recombinant human sulphamidase; rhSGSH) into the spinal CSF using a SynchroMed II® pump attached to a spinal infusion cannula...
November 10, 2016: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/27830939/burden-of-usa-hospital-charges-for-traumatic-brain-injury
#13
Jennifer R Marin, Matthew D Weaver, Rebekah C Mannix
OBJECTIVES: This study sought to estimate charges associated with USA hospital visits for traumatic brain injury (TBI), compare charges from 2006-2010 and evaluate factors associated with higher charges. METHODS: The Nationwide Emergency Department Sample database, 2006-2010, was used to estimate charges for emergency department visits and inpatient hospital stays associated with TBI and trends in charges over time were compared. Multivariable linear regression was used to evaluate factors associated with visit charges...
November 10, 2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27825644/-variability-and-suitability-of-anti-asmathic-treatment-in-pediatric-primary-health-care
#14
Cristina Suárez-Castañón, Gracia Modroño-Riaño, Gonzalo Solís-Sánchez
OBJECTIVE: To analyse the use patterns and the characteristics of anti-asmathic prescriptions in pediatric primary health care. DESIGN: Observational and retrospective study. LOCATION: Pediatric primary health care, Asturias, Spain. PARTICIPANTS: Drug prescriptions in respiratory diseases in children (<14years old) during 2011. PRINCIPAL MEASUREMENTS: Data obtained from the billing database of the Regional Health Service of Asturias and analysed by sanitary district and primary health centres, calculating the number of DDD/1...
November 5, 2016: Atencion Primaria
https://www.readbyqxmd.com/read/27806968/impact-of-the-introduction-of-rotavirus-vaccination-on-paediatric-hospital-admissions-lothian-scotland-a-retrospective-observational-study
#15
Ruth Forrest, Laura Jones, Lorna Willocks, Alison Hardie, Kate Templeton
OBJECTIVE: Rotavirus (RV) vaccination was introduced into the UK vaccination schedule in July 2013. This retrospective observational study assessed, in a UK setting, the impact of the vaccination programme on the number of RV gastroenteritis (RVGE) admissions, the complications of RVGE in hospitalised children, and the impact on hospital-acquired RVGE. DESIGN: Over a 3 year period, 1-year before and 2 years after the introduction of the vaccine, children under 13 years of age in Lothian region with RV+ve stool sample by PCR were identified, retrospectively, and admission data (length of stay, complications) and vaccination status analysed...
November 2, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27801359/bed-utilisation-in-an-irish-regional-paediatric-unit-a-cross-sectional-study-using-the-paediatric-appropriateness-evaluation-protocol-paep
#16
Coilín ÓhAiseadha, Mai Mannix, Jean Saunders, Roy K Philip
BACKGROUND: Increasing demand for limited healthcare resources raises questions about appropriate use of inpatient beds. In the first paediatric bed utilisation study at a regional university centre in Ireland, we conducted a cross-sectional study to audit the utilisation of inpatient beds at the Regional Paediatric Unit (RPU) in University Hospital Limerick (UHL), Limerick, Ireland and also examined hospital activity data, to make recommendations for optimal use of inpatient resources...
May 10, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/27792252/questionnaire-based-survey-in-a-developing-country-showing-non-compliance-with-paediatric-gastro-oesophageal-reflux-practice-guidelines
#17
Hayat Manasfi, Rima Hanna-Wakim, Imad Akel, Nadine Yazbeck
AIM: This 2015 study investigated whether Lebanese paediatricians diagnosed and managed gastroesophageal reflux disease (GERD) in infants and children in accordance with the 2009 guidelines from the North American and European Societies for Paediatric Gastroenterology, Hepatology and Nutrition. METHODS: Paediatricians members of the Lebanese Order of Physicians with updated email addresses were invited to complete a web-based survey between September and November 2015, to assess their knowledge and management of GERD...
October 28, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27790433/prevalence-of-esbl-in-escherichia-coli-isolates-among-icu-patients-in-a-tertiary-care-hospital
#18
Nipa Singh, Dipti Pattnaik, Dhruba Kumar Neogi, Jagadananda Jena, Bandana Mallick
INTRODUCTION: Resistance to common antibiotics is a matter of grave concern in treating infections in hospital settings especially in Intensive Care Units (ICUs). One of the most commonly used and effective group of antibiotics, cephalosporins, exhibit resistance due to production of Extended Spectrum Beta- Lactamases (ESBLs). The prevalence of ESBL producing Escherichia coli (E.coli) has increased throughout the world and is a major cause of treatment failure in ICUs. As per our knowledge studies were not available on the prevalence of ESBL producing E...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27784899/plasma-ang2-and-adam17-levels-are-elevated-during-clinical-malaria-ang2-level-correlates-with-severity-and-expression-of-epcr-binding-pfemp1
#19
Jens E V Petersen, Sixbert I Mkumbaye, Anna V Vaaben, Alphaxard Manjurano, Eric Lyimo, Reginald A Kavishe, Steven B Mwakalinga, Jacklin Mosha, Daniel T R Minja, John P A Lusingu, Thor G Theander, Thomas Lavstsen, Christian W Wang
The pathogenesis of Plasmodium falciparum malaria involves a complex interplay between parasite adhesion and inflammatory response that includes release of cytokines and activation of the endothelium with accompanying release of Angiopoitin 2 (Ang2) to the plasma. A-disintegrin and metalloproteinase 17 (ADAM17) is a protein responsible for releasing cytokines, including Tumor Necrosis Factor α (TNFα), and shedding of adhesion proteins. In this study, we show that plasma levels of ADAM17 are increased in Tanzanian children hospitalized with a malaria infection compared with asymptomatic children but similar to children hospitalized with other infectious diseases...
October 27, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27778076/a-retrospective-one-year-estimation-of-the-volume-and-nature-of-surgical-and-anaesthetic-services-delivered-to-the-populations-of-the-fako-division-of-the-south-west-region-of-cameroon-an-urgent-call-for-action
#20
Alain Chichom-Mefire, Victor Mbome Njie, Vincent Verla, Julius Atashili
BACKGROUND: Surgery-related conditions account for the majority of admissions in primary referral hospitals in Sub-Saharan Africa. The role of surgery in the reduction of global disease burden is well recognized, but there is a great qualitative and quantitative disparity in the delivery of surgical and anaesthetic services between countries. This study aims at estimating the nature and volume of surgery delivered in an entire administrative division of Cameroon. METHODS: In this retrospective survey conducted during the year 2013, we used a standard tool to analyse the infrastructure and human resources involved in the delivery of surgical and anaesthetic services in the Fako division in the south-west region of Cameroon...
October 24, 2016: World Journal of Surgery
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