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https://www.readbyqxmd.com/read/29786616/derivation-of-new-diagnostic-reference-levels-for-neuro-paediatric-computed-tomography-examinations-in-switzerland
#1
Franca Wagner, Julie Bize, Damien Racine, Regis Le Coultre, Verdun Francis, Philipp Trueb, Reto Treier
Definition of new national diagnostic reference levels (DRLs) for volume computed tomography dose index (CTDIvol) and dose length product (DLP) for neuro-paediatric CT examinations depending on the medical indication.
 Methods: Paediatric cranial CT data sets acquired between January 2013 and December 2016 were retrospectively collected between July 2016 and March 2017 from the eight largest university and cantonal hospitals that perform most of the neuro-paediatric CTs in Switzerland. A consensus review of CTDIvol and DLP was undertaken for the three defined anatomical regions: brain, facial bone and petrous bone; each with and without contrast medium application...
May 22, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29784656/lessons-identified-from-the-2017-manchester-and-london-terrorism-incidents-part-two-the-reception-and-definitive-care-hospital-phases
#2
REVIEW
Paul Hunt
The provision of medical care during the reception and definitive care phases of a terrorist incident will likely take place in designated receiving hospitals such as Major Trauma Centres. There is a need for an enhanced capability in such units to receive, initially manage and hold casualties with more serious injuries. Also, even less severely injured casualties may require significant time and clinical input such as risk management in potential bloodborne viruses.The distribution of casualties from the incident scene requires advance consideration of the injury pattern and regional network organisation of specialist services, such as maxillofacial, neurosurgery or severe burns care...
May 21, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29776847/a-comparative-evaluation-of-spectrophotometric-intracutaneous-analysis-and-laser-doppler-imaging-in-the-assessment-of-adult-and-paediatric-burn-injuries
#3
Somy Charuvila, Masha Singh, Declan Collins, Isabel Jones
INTRODUCTION: Clinical assessment of mid-dermal burns can be challenging. Currently, laser Doppler imaging (LDI) is the gold standard adjunct in the assessment of burn injuries. Although LDI has demonstrated reliable accuracy, it poses various limitations in routine use including cost and ease of use. In comparison, spectrophotometric intracutaneous analysis (SIA) is a relatively cheaper technique, which can be carried out using a modified digital camera that enables easy image acquisition...
March 29, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29754466/temporal-trends-in-paediatric-bacterial-meningitis-in-a-tropical-australian-region-1992-2014
#4
Stephanie White, Hala Katf, Rob Baird, Joshua Francis
AIM: The epidemiology of community-acquired bacterial meningitis has changed following the introduction of routine immunisation against common causative organisms. Indigenous children living in the Northern Territory, Australia, have high rates of bacterial infections. This study describes changes in the epidemiology of childhood bacterial meningitis and the distribution of the burden of disease in the Top End. METHODS: A retrospective review of cases derived from hospital medical records and laboratory data was performed...
May 13, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29752349/paediatric-pancreatic-neuroendocrine-tumours-in-von-hippel-lindau-disease
#5
Samuel Matthew O'Toole, Anju Sahdev, Satya Bhattacharya, Roger Feakins, Evelien F Gevers, William Drake
Extract: Pancreatic neuroendocrine tumours (pNETs) are an established feature of von Hippel-Lindau disease (VHL), occurring in up to 17% of mutation carriers (Libutti et al. 2000; Blansfield et al. 2007; Erlic et al. 2010; Igarashi et al. 2014). The natural history of VHL-pNETs is poorly characterised with metastatic disease occurring in up to 25% of affected individuals (Erlic et al. 2010). Management of this unique pNET subgroup is complicated by the potential for multifocal and metachronous disease as well as extra-pancreatic VHL-related neoplasms (e...
May 11, 2018: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29743059/enhanced-surveillance-for-tuberculosis-among-foreign-born-persons-finland-2014-2016
#6
Pirre E Räisänen, Hanna Soini, Pirjo Turtiainen, Tuula Vasankari, Petri Ruutu, J Pekka Nuorti, Outi Lyytikäinen
BACKGROUND: Tuberculosis (TB) in foreign-born residents is increasing in many European countries including Finland. We conducted enhanced TB surveillance to collect supplementary information on TB cases among recent immigrants and their children to provide data for revising TB control policies in Finland to take into account the decrease in native cases and increase in foreign-born cases. METHODS: TB cases were identified from the National Infectious Diseases Register...
May 9, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29740714/xpert-mtb-rif-diagnosis-of-childhood-tuberculosis-from-sputum-and-stool-samples-in-a-high-tb-hiv-prevalent-setting
#7
Patrick Orikiriza, Margaret Nansumba, Dan Nyehangane, Mathieu Bastard, Ivan Taremwa Mugisha, Denis Nansera, Juliet Mwanga-Amumpaire, Yap Boum, Elias Kumbakumba, Maryline Bonnet
The Xpert MTB/RIF assay is a major advance for diagnosis of tuberculosis (TB) in high-burden countries but is limited in children by their difficulty to produce sputum. We investigated TB in sputum and stool from children with the aim of improving paediatric TB diagnosis. A prospective cohort of children with presumptive TB, provided two sputum or induced sputum at enrolment in a regional referral hospital in Uganda. Stool was collected from those started on TB treatment. All specimen were tested for Xpert MTB/RIF, mycobacteria growth indicator tube (MGIT), Lowenstein Jensen cultures and microscopy (except stool)...
May 8, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29737317/first-robotic-pylorus-preserving-pancreaticoduodenectomy-for-frantz-s-tumour-in-an-adolescent-girl
#8
Palanivelu Chinnusamy, Sumanta Dey, Bhushan Chittawadagi, Srivatsan Gurumurthy, Sandeep Sabnis, Senthilnathan Palanisamy
Solid pseudopapillary tumour (SPT) is one of the uncommon benign cystic neoplasms of pancreas occurring predominantly in young females. Being benign in nature, surgical resection is the treatment of choice with excellent 5-year survival. A 14-year-old girl presented with pain abdomen for 1 week. On evaluation, she was found to have a large SPT involving head and uncinate process of Pancreas She underwent robotic pylorus preserving pancreaticoduodenectomy (R-PPPD) with da Vinci® Si Robotic System (Intuitive Surgical, Sunnyvale, CA, USA)...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29730620/predicting-risk-of-hospitalisation-a-retrospective-population-based-analysis-in-a-paediatric-population-in-emilia-romagna-italy
#9
Daniel Z Louis, Clara A Callahan, Mary Robeson, Mengdan Liu, Jacquelyn McRae, Joseph S Gonnella, Marco Lombardi, Vittorio Maio
OBJECTIVES: Develop predictive models for a paediatric population that provide information for paediatricians and health authorities to identify children at risk of hospitalisation for conditions that may be impacted through improved patient care. DESIGN: Retrospective healthcare utilisation analysis with multivariable logistic regression models. DATA: Demographic information linked with utilisation of health services in the years 2006-2014 was used to predict risk of hospitalisation or death in 2015 using a longitudinal administrative database of 527 458 children aged 1-13 years residing in the Regione Emilia-Romagna (RER), Italy, in 2014...
May 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29728418/understanding-case-mix-across-three-paediatric-services-could-integration-of-primary-and-secondary-general-paediatrics-alter-walk-in-emergency-attendances
#10
Lloyd Steele, Nicky Coote, Robert Klaber, Mando Watson, Michael Coren
OBJECTIVE: To understand the case mix of three different paediatric services, reasons for using an acute paediatric service in a region of developing integrated care and where acute attendances could alternatively have been managed. METHODS: Mixed methods service evaluation, including retrospective review of referrals to general paediatric outpatients (n=534) and a virtual integrated service (email advice line) (n=474), as well as a prospective survey of paediatric ambulatory unit (PAU) attendees (n=95) and review by a paediatric consultant/registrar to decide where these cases could alternatively have been managed...
May 4, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29726390/the-my-child-matters-programme-effect-of-public-private-partnerships-on-paediatric-cancer-care-in-low-income-and-middle-income-countries
#11
REVIEW
Scott C Howard, Alia Zaidi, Xueyuan Cao, Olivier Weil, Pierre Bey, Catherine Patte, Angelica Samudio, Laurie Haddad, Catherine G Lam, Claude Moreira, Augusto Pereira, Mhamed Harif, Laila Hessissen, Salma Choudhury, Ligia Fu, Miguela A Caniza, Julius Lecciones, Fousseyni Traore, Raul C Ribeiro, Anne Gagnepain-Lacheteau
In low-income and middle-income countries, an excess in treatment failure for children with cancer usually results from misdiagnosis, inadequate access to treatment, death from toxicity, treatment abandonment, and relapse. The My Child Matters programme of the Sanofi Espoir Foundation has funded 55 paediatric cancer projects in low-income and middle-income countries over 10 years. We assessed the impact of the projects in these regions by using baseline assessments that were done in 2006. Based on these data, estimated 5-year survival in 2016 increased by a median of 5·1%, ranging from -1·5% in Venezuela to 17·5% in Ukraine...
May 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29723913/observational-pre-post-study-showed-that-a-quality-improvement-project-reduced-paediatric-antibiotic-prescribing-rates-in-primary-care
#12
Simona Di Mario, Carlo Gagliotti, Rossella Buttazzi, Luca Cisbani, Chiara Di Girolamo, Antonio Brambilla, Maria Luisa Moro
AIM: This study assessed the effectiveness of a quality improvement project that aimed to promote more considered antibiotic prescribing in paediatric primary care. Method This was an observational pre-post study that used patient-level prescribing data from the Emilia-Romagna region of Italy to monitor indicators from 2005 to 2016. Multilevel interventions and activities started in 2007 and these included developing guidelines and updates, disseminating evidence, audits and feedback, public information campaigns, engaging health managers and performance incentives...
May 3, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29721345/a-midgut-duplication-cyst-lined-by-respiratory-epithelium
#13
Balaji Mahendran, Tim Bracey, Rajesh T Kochupapy
Duplication cysts are an uncommon finding. Majority of these cases are found in the region of the midgut, and many have been reported in literature. However, there has been only one previous case of a midgut duplication cyst lined by respiratory epithelium. This is a rare pathology, of which very little is known about. The pathophysiology of these cases is also difficult to explain. We aim to present a case of a midgut duplication cyst in a paediatric patient, who had other abnormalities as well. We also aim to offer a hypothesis for this case...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29707516/communication-rehabilitation-in-sub-saharan-africa-the-role-of-speech-and-language-therapists
#14
Karen Wylie, Lindy McAllister, Bronwyn Davidson, Julie Marshall
Background: Workforce factors present a significant barrier to the development of rehabilitation services for people with communication disabilities in sub-Saharan Africa (SSA). Exploring how the work of speech and language therapists (SLTs) in the region is organised and delivered can provide insight into existing services, areas for future workforce development and improved rehabilitation access for people with communication disability. Objectives: This paper describes the employment and service provision patterns and work roles of a sample of SLTs in SSA...
2018: African Journal of Disability
https://www.readbyqxmd.com/read/29704905/the-development-of-a-consensus-based-nutritional-pathway-for-infants-with-chd-before-surgery-using-a-modified-delphi-process
#15
Luise V Marino, Mark J Johnson, Nigel J Hall, Natalie J Davies, Catherine S Kidd, M Lowri Daniels, Julia E Robinson, Trevor Richens, Tara Bharucha, Anne-Sophie E Darlington
IntroductionDespite improvements in the medical and surgical management of infants with CHD, growth failure before surgery in many infants continues to be a significant concern. A nutritional pathway was developed, the aim of which was to provide a structured approach to nutritional care for infants with CHD awaiting surgery.Materials and methodsThe modified Delphi process was development of a nutritional pathway; initial stakeholder meeting to finalise draft guidelines and develop questions; round 1 anonymous online survey; round 2 online survey; regional cardiac conference and pathway revision; and final expert meeting and pathway finalisation...
April 29, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29704520/trends-in-the-incidence-and-outcome-of-paediatric-out-of-hospital-cardiac-arrest-a-17-year-observational-study
#16
Ziad Nehme, Siva Namachivayam, Anri Forrest, Warwick Butt, Stephen Bernard, Karen Smith
BACKGROUND: System-based improvements to the chain of survival have yielded increases in survival from out-of-hospital cardiac arrest (OHCA) in adults. Comparatively little is known about the long-term trends in incidence and survival following paediatric OHCA. METHODS: Between 2000 and 2016, we included children aged ≤16 years who suffered a non-traumatic OHCA in the state of Victoria, Australia. Trends in incidence and unadjusted outcomes were assessed using linear regression and a non-parametric test for trend...
April 25, 2018: Resuscitation
https://www.readbyqxmd.com/read/29701240/a-10-year-longitudinal-follow-up-study-of-a-uk-paediatric-transplant-population-to-assess-for-skin-cancer
#17
S H Foo, P G Nightingale, P Gazzani, E Bader, M Ogboli, A Martin-Clavijo, D V Milford, D A Kelly, C Moss, M A Thomson
BACKGROUND: Our earlier study published in 2004 1 found no skin cancer in a cohort of paediatric organ transplant recipients (POTRs) 5 to 16 years post-transplantation. We re-evaluated the same cohort 10 years later. OBJECTIVES: To determine the prevalence of premalignant and malignant skin lesions and identify known risk factors associated with melanocytic naevi in a UK paediatric transplant population. METHODS: Ninety eight POTRs from the original 2004 study were invited to participate in this longitudinal follow-up study...
April 27, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29700892/prevention-of-perioperative-venous-thromboembolism-in-pediatric-patients-guidelines-from-the-association-of-paediatric-anaesthetists-of-great-britain-and-ireland-apagbi
#18
Judith Morgan, Matthew Checketts, Amaia Arana, Elizabeth Chalmers, Jamie Maclean, Mark Powis, Neil Morton
The Association of Paediatric Anaesthetists of Great Britain and Ireland (APAGBI) Guidelines Working Group on Thromboprophylaxis in Children has reviewed the literature and where possible provided advice on the care of children in the perioperative period. Areas reviewed include the incidence of perioperative venous thromboembolism (VTE), risk factors, evidence for mechanical and chemical prophylaxis, and complications. Safe practice of regional anesthesia with anticoagulant prophylaxis is detailed. In summary, there are few areas of strong evidence...
April 27, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29699897/development-of-regional-extracorporeal-life-support-system-the-importance-of-innovative-simulation-training
#19
Mateusz Puślecki, Marcin Ligowski, Marek Dąbrowski, Sebastian Stefaniak, Małgorzata Ładzińska, Aleksander Pawlak, Marcin Zieliński, Łukasz Szarpak, Bartłomiej Perek, Marek Jemielity
BACKGROUND: Despite advances in mechanical ventilation, severe acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality rates ranging from 30% to 60%. Extracorporeal Membrane Oxygenation (ECMO) can be used as a "bridge to recovery". ECMO is a complex network that provides oxygenation and ventilation and allows the lungs to rest and recover from respiratory failure, while minimizing iatrogenic ventilator-induced lung injury. In the critical care settings, ECMO is shown to improve survival rates and outcomes in patients with severe ARDS...
April 18, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29690971/clinical-spectrum-and-outcome-of-cerebral-venous-sinus-thrombosis-in-children
#20
Iram Javed, Tipu Sultan, Zia Ur Rehman, Muhammad Rizwan Yaseen
OBJECTIVE: To determine clinical spectrum, neuroimaging finding and outcome of cerebral venous sinus thrombosis (CVST) in children. STUDY DESIGN: Descriptive and cross-sectional study. PLACE AND DURATION OF STUDY: Department of Paediatric Neurology, Children's Hospital and Institute of Child Health, Lahore, from 2015 to 2016. METHODOLOGY: Data was collected in a predesigned proforma by non-probability purposive sampling technique from all enrolled 32 patients fulfilling the inclusion criteria...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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