keyword
MENU ▼
Read by QxMD icon Read
search

RPE

keyword
https://www.readbyqxmd.com/read/29452908/gait-and-posture-analysis-in-patients-with-maxillary-transverse-discrepancy-before-and-after-rpe
#1
Martina Mason, Fabiola Spolaor, Annamaria Guiotto, Alberto De Stefani, Antonio Gracco, Zimi Sawacha
AIM: The purpose of this study was to evaluate the effects of the rapid palatal expansion (RPE) on posture and gait analysis in subjects with maxillary transverse discrepancies. MATERIAL AND METHODS: Forty-one patients between 6 and 12 years were divided into 3 groups: 10 control subjects (Cs), 16 patients with unilateral posterior crossbite (CbMono), 15 patients with maxillary transverse discrepancy and no crossbite (Nocb). Every subject underwent gait analysis and posturographic examination in order to evaluate the presence of balance alterations before (T0) and after (T4) RPE application...
February 13, 2018: International Orthodontics
https://www.readbyqxmd.com/read/29451602/synthesis-and-cytotoxic-evaluation-of-1h-1-2-3-triazol-1-ylmethyl-2-3-dihydronaphtho-1-2-b-furan-4-5-diones
#2
Ingrid C Chipoline, Evelyne Alves, Paola Branco, Leticia V Costa-Lotufo, Vitor F Ferreira, Fernando C DA Silva
The 1,2-naphthoquinone compound was previously considered active against solid tumors. Moreover, glycosidase inhibitors such as 1,2,3-1H triazoles has been pointed out as efficient compounds in anticancer activity studies. Thus, a series of eleven 1,2-naphthoquinones tethered in C2 to 1,2,3-1H-triazoles 9a-k were designed, synthesized and their cytotoxic activity evaluated using HCT-116 (colon adenocarcinoma), MCF-7 (breast adenocarcinoma) and RPE (human nontumor cell line from retinal epithelium). The chemical synthesis was performed from C-3 allylation of lawsone followed by iodocyclization with subsequent nucleophilic displacement with sodium azide and, finally, the 1,3-dipolar cycloaddition catalyzed by Cu(I) with terminal alkynes led to the formation of 1H-1,2,3-Triazol-1-ylmethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diones in good yields...
February 15, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29450540/endocan-blockade-suppresses-experimental-ocular-neovascularization-in-mice
#3
Ting Su, Yisheng Zhong, Anna M Demetriades, Jikui Shen, Ailing Sui, Yiyun Yao, Yushuo Gao, Yanji Zhu, Xi Shen, Bing Xie
Purpose: Ocular neovascularization (NV) is a pathologic process characterized by the proliferation and infiltration of various types of cells such as RPE, glial, and endothelial cells, which interact with proangiogenic factors and inflammatory cytokines. Endocan is known to be enriched in retinal endothelial tip cells under hypoxia, but the effect of endocan on ocular NV progression is largely unknown. In this study, we investigated the role of endocan in the ocular NV pathologic process and the possible mechanisms involved...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29445097/complete-transcriptome-profiling-of-normal-and-age-related-macular-degeneration-eye-tissues-reveals-dysregulation-of-anti-sense-transcription
#4
Eun Ji Kim, Gregory R Grant, Anita S Bowman, Naqi Haider, Harini V Gudiseva, Venkata Ramana Murthy Chavali
Age-related macular degeneration (AMD) predominantly affects the retina and retinal pigment epithelium in the posterior eye. While there are numerous studies investigating the non-coding transcriptome of retina and RPE, few significant differences between AMD and normal tissues have been reported. Strand specific RNA sequencing of both peripheral retina (PR) and RPE-Choroid-Sclera (PRCS), in both AMD and matched normal controls were generated. The transcriptome analysis reveals a highly significant and consistent impact on anti-sense transcription as well as moderate changes in the regulation of non-coding (sense) RNA...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29444414/no-individual-or-combined-effects-of-caffeine-and-beetroot-juice-supplementation-during-submaximal-or-maximal-running
#5
Johanna Oskarsson, Kerry McGawley
BACKGROUND: Dietary supplements such as caffeine and beetroot juice are used by athletes in an attempt to optimize performance and therefore gain an advantage in competition. AIM: To investigate the individual and combined effects of caffeine and beetroot-juice supplementation during submaximal and maximal treadmill running. METHODS: Seven males (VO<sub>2max</sub>: 59.0 ± 2.9 mL/kg/min) and two females (VO<sub>2max</sub>: 53...
February 14, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29443034/subretinal-transplantation-of-human-embryonic-stem-cell-derived-retinal-pigment-epithelial-cells-into-a-large-eyed-model-of-geographic-atrophy
#6
Sandra Petrus-Reurer, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Fredrik Lanner, Anders Kvanta
Geographic atrophy (GA), the late stage of dry age-related macular degeneration is characterized by loss of the retinal pigment epithelial (RPE) layer, which leads to subsequent degeneration of vital retinal structures (e.g., photoreceptors) causing severe vision impairment. Similarly, RPE-loss and decrease in visual acuity is seen in long-term follow up of patients with advanced wet age-related macular degeneration (AMD) receiving intravitreal anti-vascular endothelial growth factor (VEGF) treatment. Therefore, on the one hand, it is fundamental to efficiently derive RPE cells from an unlimited source that could serve as replacement therapy...
January 22, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29439750/differential-neural-reward-mechanisms-in-treatment-responsive-and-treatment-resistant-schizophrenia
#7
Lucy D Vanes, Elias Mouchlianitis, Tracy Collier, Bruno B Averbeck, Sukhi S Shergill
BACKGROUND: The significant proportion of schizophrenia patients refractory to treatment, primarily directed at the dopamine system, suggests that multiple mechanisms may underlie psychotic symptoms. Reinforcement learning tasks have been employed in schizophrenia to assess dopaminergic functioning and reward processing, but these have not directly compared groups of treatment-refractory and non-refractory patients. METHODS: In the current functional magnetic resonance imaging study, 21 patients with treatment-resistant schizophrenia (TRS), 21 patients with non-treatment-resistant schizophrenia (NTR), and 24 healthy controls (HC) performed a probabilistic reinforcement learning task, utilizing emotionally valenced face stimuli which elicit a social bias toward happy faces...
February 14, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29436636/effects-of-bradykinin-on-tgf%C3%A2-%C3%AE-1%C3%A2-induced-epithelial%C3%A2-mesenchymal-transition-in-arpe%C3%A2-19-cells
#8
Qingquan Wei, Qingyu Liu, Chengda Ren, Junling Liu, Wenting Cai, Meijiang Zhu, Huizi Jin, Mengmei He, Jing Yu
The aim of the present study was to investigate the effects of bradykinin (BK) on an epithelial-mesenchymal transition (EMT) model in retinal pigment epithelium (RPE) cells through exposure to transforming growth factor‑β1 (TGF‑β1). The aim was to improve the effect of BK on proliferative vitreoretinopathy (PVR) progression, and to find a novel method of clinical prevention and treatment for PVR. The morphology of ARPE‑19 cells was observed using an inverted phase‑contrast microscope. A Cell Counting Kit‑8 was used to assess the effects of TGF‑β1 on the proliferation of ARPE‑19 cells...
February 2, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29435412/mirnaexpression-profile-of-retinal-pigment-epithelial-cells-under-oxidative-stress-conditions
#9
Luigi Donato, Placido Bramanti, Concetta Scimone, Carmela Rinaldi, Rosalia D'Angelo, Antonina Sidoti
Deep analysis of regulative mechanisms of transcription and translation in eukaryotes could improve knowledge of many genetic pathologies such as retinitis pigmentosa (RP). New layers of complexity have recently emerged with the discovery that 'junk' DNA is transcribed and, among these, miRNAs have assumed a preponderant role. We compared changes in the expression of miRNAs obtained from whole transcriptome analyses, between two groups of retinal pigment epithelium (RPE) cells, one untreated and the other exposed to the oxidant agent oxidized low-density lipoprotein (oxLDL), examining four time points (1, 2, 4 and 6 h)...
February 2018: FEBS Open Bio
https://www.readbyqxmd.com/read/29435333/combining-perceptual-regulation-and-exergaming-for-exercise-prescription-in-low-active-adults-with-and-without-cognitive-impairment
#10
Liam McAuliffe, Gaynor C Parfitt, Roger G Eston, Caitlin Gray, Hannah A D Keage, Ashleigh E Smith
 Background: Exercise adherence in already low-active older adults with and without mild cognitive impairment (MCI) remains low. Perceptual regulation and exergaming may facilitate future exercise behaviour by improving the affective experience, however evidence that this population can perceptually regulate is lacking. To explore this, we investigated 1) perceptual regulation of exercise intensity during either exergaming or regular ergometer cycling and 2) explored affective responses...
2018: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29434083/survey-of-awareness-about-hazardous-chemicals-of-residents-living-near-chemical-plants-in-south-korea
#11
Don-Hee Han, Min Soo Park
With economic growth, the use of chemicals has continually increased, resulting in an increase of chemical accidents. Chemical accidents pose a life threat and can lead to many health problems among the residents living in close proximity to chemical plants. This study aimed to investigate the awareness of the residents living near chemical plants about hazardous chemicals, as well as to survey the awareness of workers who do not directly handle chemicals at chemical plants (WNHCs). To this end, a questionnaire survey was conducted among a total of 600 residents and 160 WNHCs...
February 10, 2018: Industrial Health
https://www.readbyqxmd.com/read/29432324/classification-of-intensity-in-team-sport-activity
#12
Ted Polglaze, Cruz Hogan, Brian Dawson, Alec Buttfield, Cristian Osgnach, Leanne Lester, Peter Peeling
PURPOSE: To assess the efficacy of critical metabolic power derived from variable-speed movement for classifying intensity in team sport activity. METHODS: Elite male hockey players (n = 12) completed a series of time trials (100 yd, 400 yd, 1500 yd) and a 3-min all-out test to derive both critical speed (CS) and critical power (CP). Heart rate (HR), blood lactate (BLa) and rating of perceived exertion (RPE) were measured during each protocol. Participants (n = 10) then played 2 competitive hockey matches...
February 9, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29431589/development-of-a-golf-specific-load-monitoring-tool-content-validity-and-feasibility
#13
Scott B Williams, Paul B Gastin, Anna E Saw, Sam Robertson
Athletes often record details of their training and competitions, supported by information such as environmental conditions, travel, as well as how they felt. However, it is not known how prevalent these practices are in golfers, or how valuable this process is perceived. The purpose of this study was to develop a golf-specific load monitoring tool (GLMT), and establish the content validity and feasibility of this tool amongst high-level golfers. In the first phase of development, 21 experts were surveyed to determine the suitability of items for inclusion in the GLMT...
February 12, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29430940/positive-effects-of-a-short-term-intense-elastic-resistance-training-program-on-body-composition-and-physical-functioning-in-overweight-older-women
#14
Nicole B Fritz, Álvaro Juesas, Pedro Gargallo, Joaquín Calatayud, Julio Fernández-Garrido, Michael E Rogers, Juan C Colado
The aim of this study was to investigate the effects of a resistance training program (RTP) in older overweight women (OOW) using two different types of elastic devices. METHODS: This study was a randomized controlled trial with pre- and postintervention measures. Participants included OOW, aged 60-85 years, with no medical history of disease that would preclude them from engaging in physical exercise. Participants were randomly divided into the following groups: elastic tubes with handles group (ETG; n = 22), traditional elastic bands group ( n = 21), and control group (CG; n = 20)...
January 1, 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/29427790/activation-of-nrf2-by-ginsenoside-rh3-protects-retinal-pigment-epithelium-cells-and-retinal-ganglion-cells-from-uv
#15
Chun-Zhou Tang, Ke-Ran Li, Qing Yu, Qin Jiang, Jin Yao, Cong Cao
Excessive Ultra-violet (UV) radiation shall induce damages to resident retinal pigment epithelium (RPE) cells (RPEs) and retinal ganglion cells (RGCs). Here we tested the potential activity of Ginsenoside Rh3 ("Rh3") against the process. In cultured human RPEs and RGCs, pretreatment with Rh3 inhibited UV-induced reactive oxygen species (ROS) production and following apoptotic/non-apoptotic cell death. Rh3 treatment in retinal cells induced nuclear-factor-E2-related factor 2 (Nrf2) activation, which was evidenced by Nrf2 protein stabilization and its nuclear translocation, along with transcription of antioxidant responsive element (ARE)-dependent genes (HO1, NOQ1 and GCLC)...
February 7, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29425971/competition-stage-influences-perceived-performance-but-does-not-affect-rating-of-perceived-exertion-and-salivary-neuro-endocrine-immune-markers-in-elite-young-basketball-players
#16
Ademir Felipe Schultz de Arruda, Marcelo Saldanha Aoki, Ana Carolina Paludo, Gustavo Drago, Alexandre Moreira
This study examined the effects of competition stage on the salivary concentration of testosterone (T), cortisol (C), alpha-amylase (sAA), and IL-1ß cytokine, perceived performance (PP) and session rating of perceived exertion (session-RPE) in elite youth basketball players (age, 15.8 ± 0.8 yrs.; stature, 190.9 ± 7.9 cm; body mass, 90.0 ± 16.9 kg) from two age-categories (U16; n = 7; U17; n = 7). Two winning playoff matches (FM; playing for the championship; 1 for each age-category) and two winning regular stage matches (RM; 1 for each age category, played against opponents ranked 2nd place), were assessed in the current study...
February 6, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29421579/polyphenol-enriched-extract-of-rosa-rugosa-thunb-regulates-lipid-metabolism-in-diabetic-rats-by-activation-of-ampk-pathway
#17
Liu Liu, Mireguli Yasen, Dan Tang, Jianping Ye, Haji Akber Aisa, Xuelei Xin
This study was designed to investigate the mechanism of polyphenol-enriched extract of Rosa rugosa Thunb (RPE) in the control of dyslipidemia in diabetic rats. RPE was tested at three dosages (37.5 mg/kg, 75 mg/kg and 150 mg/kg) in the rat dyslipidemia model established with high fat diet feeding in combination with STZ injection (30 mg/kg). The RPE effect was evaluated after 4 weeks of treatment. In the RPE-treated rats, hepatic total cholesterol (TC) and triglyceride (TG) were significantly reduced, lipoprotein lipase (LPL) and liver lipase (HL) were significantly increased...
February 5, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29417735/fetal-bovine-serum-can-reduce-toxicity-of-indocyanine-green-brilliant-blue-g-and-trypan-blue-in-arpe-19-cellular-model-that-suggests-new-surgical-staining-protocols-for-internal-limiting-membrane-peeling-procedure
#18
Yu-Yi Lin, Jorn-Hon Liu, Yin Chang
BACKGROUND: To investigate and compare the cytotoxicity of indocyanine green (ICG), brilliant blue G (BBG) and trypan blue (TB) using ARPE-19 cells that have been pre-treated/post- treated with balanced salt solution (BSS) or fetal bovine serum (FBS). METHODS: The cultured human retina pigment epithelium (RPE) ARPE-19 cells were pre-treated/post-treated with BSS or FBS (represent the autologous serum in clinic) in parallel with cells being soaked with various concentrations of ICG, BBG, and TB...
February 8, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29415988/photosensitization-of-a2e-triggers-telomere-dysfunction-and-accelerates-retinal-pigment-epithelium-senescence
#19
Jing Wang, Yiji Feng, Peng Han, Fenghua Wang, Xueting Luo, Jian Liang, Xiangjun Sun, Jing Ye, Yiming Lu, Xiaodong Sun
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in elderly people. AMD is classified as early, intermediate, advanced non-neovascular, and advanced neovascular forms depending on the clinical features. However, the exact pathogenesis remains unclear. Retinal pigment epithelium (RPE) cells degeneration is a hallmark of AMD. With aging, lipofuscin accumulates in RPE cells. N-retinylidene-N-retinylethanolamine (named A2E), a well-known fluorophore of lipofuscin, may contribute to RPE cells degeneration...
February 7, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29415927/-development-of-alternatives-to-animal-experiments-using-pluripotent-stem-cells
#20
Koichi Saito, Noriyuki Suzuki, Kumiko Kobayashi
Animal experiments have occupied an important position in the safety assessment of chemicals. However, due to the rise in animal welfare as seen in the ban of animal experiments in European cosmetic development, the development of alternative methods for animal experiments has become very important in recent years. Development of in vitro tests for local toxicity such as irritation and sensitization tests is preceded. Meanwhile, alternative tests for systemic toxicity such as chronic and developmental toxicities are under development...
2018: Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
keyword
keyword
99646
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"