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https://www.readbyqxmd.com/read/29333349/annual-and-spatial-variation-in-composition-and-activity-of-terrestrial-mammals-on-two-replicate-plots-in-lowland-forest-of-eastern-ecuador
#1
John G Blake, Bette A Loiselle
Terrestrial mammals are important components of lowland forests in Amazonia (as seed dispersal agents, herbivores, predators) but there are relatively few detailed studies from areas that have not been affected by human activities (e.g., hunting, logging). Yet, such information is needed to evaluate effects of humans elsewhere. We used camera traps to sample medium to large-sized terrestrial mammals at a site in lowland forests of eastern Ecuador, one of the most biologically rich areas in the world. We deployed cameras on two study plots in terra firme forest at Tiputini Biodiversity Station...
2018: PeerJ
https://www.readbyqxmd.com/read/29332996/optimal-population-and-exhaustible-resource-constraints
#2
Nicholas Lawson, Dean Spears
A large literature considers the optimal size and growth rate of the human population, trading off the utility value of additional people with the costs of a larger population. In this literature, an important parameter is the social weight placed on population size; a standard result is that a planner with a larger weight on population chooses larger population levels and growth rates. We demonstrate that this result is conditionally overturned when an exhaustible resource constraint is introduced: if the discount rate is small enough, the optimal population today decreases with the welfare weight on population size...
January 2018: Journal of Population Economics
https://www.readbyqxmd.com/read/29331855/retrievable-inferior-vena-cava-filters-in-pregnancy-risk-versus-benefit
#3
REVIEW
David A Crosby, Kevin Ryan, Niall McEniff, Patrick Dicker, Carmen Regan, Caoimhe Lynch, Bridgette Byrne
OBJECTIVE: Venous thromboembolism remains one of the leading causes of maternal mortality in the developed world. Retrievable inferior vena cava (IVC) filters have a role in the prevention of lethal pulmonary emboli when anticoagulation is contraindicated or has failed [1]. It is unclear whether or not the physiological changes in pregnancy influence efficacy and complications of these devices. The decision to place an IVC filter in pregnancy is complex and there is limited information in terms of benefit and risk to the mother...
December 21, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29329288/soil-transmitted-helminth-infection-loss-of-education-and-cognitive-impairment-in-school-aged-children-a-systematic-review-and-meta-analysis
#4
Noel Pabalan, Eloisa Singian, Lani Tabangay, Hamdi Jarjanazi, Michael J Boivin, Amara E Ezeamama
BACKGROUND: Evidence of an adverse influence of soil transmitted helminth (STH) infections on cognitive function and educational loss is equivocal. Prior meta-analyses have focused on randomized controlled trials only and have not sufficiently explored the potential for disparate influence of STH infection by cognitive domain. We re-examine the hypothesis that STH infection is associated with cognitive deficit and educational loss using data from all primary epidemiologic studies published between 1992 and 2016...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29327701/distribution-of-killer-immunoglobulin-like-receptor-genes-in-hiv-infected-long-term-non-progressors-from-mumbai-india
#5
Vijay R Chavan, Zakiya Ansari, Preeti Mehta, Jayanti Mania-Pramanik
BACKGROUND: Few reports suggest the association of killer immunoglobulin-like receptors of natural killer cells with human immunodeficiency virus infection. India with world's third largest population of human immunodeficiency virus / acquired immunodeficiency syndrome, offers scope to study such association. OBJECTIVE: Current study (2010-2015) was designed to evaluate if killer immunoglobulin-like receptors gene polymorphisms are associated with HIV infection outcomes specifically, with long term non progressors...
January 12, 2018: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29325940/clinical-features-treatment-and-prognostic-factors-of-56-intracranial-and-intraspinal-clear-cell-meningiomas
#6
Xiaogang Tao, Jinqian Dong, Zonggang Hou, Shuyu Hao, Junting Zhang, Zhen Wu, Baiyun Liu
OBJECTIVE: Intracranial and intraspinal clear cell meningiomas (CCMs) are rarely reported because of their extremely low incidence, and the current understanding of CCM is poor. The purpose of this study was to analyze the incidence and the clinical, radiological, pathological, and prognostic features of intracranial and intraspinal CCMs. METHODS: Among 14310 cases of intracranial and intraspinal meningiomas that were surgically treated between 2006 and 2016 at Beijing Tian Tan Hospital, 56 were chosen for analysis and retrospectively reviewed...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29325774/achievement-of-guideline-targets-for-blood-pressure-lipid-and-glycaemic-control-in-type-2-diabetes-a-meta-analysis
#7
REVIEW
Kamlesh Khunti, Antonio Ceriello, Xavier Cos, Christophe De Block
We assessed global achievement of targets recommended by the American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD), and National Institute of Health and Care Excellence (NICE) for type 2 diabetes. We searched Medline, Embase, and The Cochrane Library for observational studies reporting target attainment (2006 to 2017 inclusive) for HbA1c, blood pressure, or lipids (low density lipoprotein cholesterol [LDL-C], high density lipoprotein cholesterol [HDL-C], or triglycerides)...
January 8, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29325554/an-analysis-of-the-global-pharmacy-workforce-capacity-trends-from-2006-to-2012
#8
Ian Bates, Christopher John, Priyanka Seegobin, Andreia Bruno
BACKGROUND: Human resources for health are at a critical low. The World Health Organization estimates that the current shortage of health workers, including pharmacists, is in excess of 7.2 million worldwide and that, by 2035, the shortage will reach 12.9 million. Pharmacists, in particular, are lacking in the workforce in many countries. The International Pharmaceutical Federation (FIP) and academic partners have conducted periodic global pharmacy workforce surveys in 2006, 2009 and 2012 which have monitored and reported on the status of the pharmacy workforce at the country and territory levels...
January 11, 2018: Human Resources for Health
https://www.readbyqxmd.com/read/29325516/brucellosis-remains-a-neglected-disease-in-the-developing-world-a-call-for-interdisciplinary-action
#9
K A Franc, R C Krecek, B N Häsler, A M Arenas-Gamboa
BACKGROUND: Brucellosis is an endemic zoonotic disease in most of the developing world that causes devastating losses to the livestock industry and small-scale livestock holders. Infected animals exhibit clinical signs that are of economic significance to stakeholders and include reduced fertility, abortion, poor weight gain, lost draught power, and a substantial decline in milk production. In humans, brucellosis typically manifests as a variety of non-specific clinical signs. Chronicity and recurring febrile conditions, as well as devastating complications in pregnant women are common sequelae...
January 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29322919/hadamard-kernel-svm-with-applications-for-breast-cancer-outcome-predictions
#10
Hao Jiang, Wai-Ki Ching, Wai-Shun Cheung, Wenpin Hou, Hong Yin
BACKGROUND: Breast cancer is one of the leading causes of deaths for women. It is of great necessity to develop effective methods for breast cancer detection and diagnosis. Recent studies have focused on gene-based signatures for outcome predictions. Kernel SVM for its discriminative power in dealing with small sample pattern recognition problems has attracted a lot attention. But how to select or construct an appropriate kernel for a specified problem still needs further investigation...
December 21, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29322101/a-novel-individual-level-morphological-brain-networks-constructing-method-and-its-evaluation-in-pet-and-mr-images
#11
Jiehui Jiang, Hucheng Zhou, Huoqiang Duan, Xin Liu, Chuantao Zuo, Zhemin Huang, Zhihua Yu, Zhuangzhi Yan
Mapping the human brain is one of the great scientific challenges of the 21st century. Brain network analysis is an effective technique based on graph theory that is widely used to investigate network patterns in the human brain. Currently, mapping an individual brain network using a single image has been a hotspot in the field of brain science; techniques, such as the Kullback-Leibler (KL) method, have applications in structural Magnetic Resonance (MR) imaging. However, maintaining an image's intensity, shape, texture and gradient information during feature extraction is very challenging...
December 2017: Heliyon
https://www.readbyqxmd.com/read/29321345/genetic-variability-and-structure-of-an-isolated-population-of-ambystoma-altamirani-a-mole-salamander-that-lives-in-the-mountains-of-one-of-the-largest-urban-areas-in-the-world
#12
Rosa-Laura Heredia-Bobadilla, Octavio Monroy-Vilchis, Martha M Zarco-González, Daniel Martínez-Gómez, Germán David Mendoza-Martínez, Armando Sunny
Amphibians are globally threatened by habitat loss and fragmentation; species within the order Ambystoma are not the exception, as there are 18 species of mole salamanders in México, of which 16 are endemic and all species are under some national or international status of protection. The mole salamander, Ambystoma altamirani is a microendemic species, which is distributed in central México, within the trans-Mexican volcanic belt, and is one of the most threatened species due to habitat destruction and the introduction of exotic species...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29319199/histopathological-frequency-of-feline-hepatobiliary-disease-in-the-uk
#13
W A Bayton, C Westgarth, T Scase, D J Price, N H Bexfield
OBJECTIVES: To determine the histopathological frequency of feline hepatobiliary diseases in the UK and to identify breed, age and gender predispositions to developing individual diseases. METHODS: Histopathology results from 1452 feline liver biopsies were assessed. A control population of microchipped cats was used for breed comparison. Data were retrospectively categorised into hepatobiliary diseases according to World Small Animal Veterinary Association standards...
January 10, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29318488/disrupted-topological-organization-of-the-frontal-mesolimbic-network-in-obese-patients
#14
Qianqian Meng, Yu Han, Gang Ji, Guanya Li, Yang Hu, Li Liu, Qingchao Jin, Karen M von Deneen, Jizheng Zhao, Guangbin Cui, Huaning Wang, Dardo Tomasi, Nora D Volkow, Jixin Liu, Yongzhan Nie, Yi Zhang, Gene-Jack Wang
Neuroimaging studies have revealed brain functional abnormalities in frontal-mesolimbic regions in obesity. However, the effects of obesity on brain network topology remains largely unknown. In the current study, we employed resting-state functional magnetic resonance imaging and graph theory methods to investigate obesity-related changes in brain network topology in 26 obese patients and 28 normal weight subjects. Results revealed that the whole-brain networks of the two groups exhibited typical features of small-world topology...
January 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29318385/transcription-factor-network-efficiency-in-the-regulation-of-candida-albicans-biofilms-it-is-a-small-world
#15
Virginia E Glazier, Damian J Krysan
Complex biological processes are frequently regulated through networks comprised of multiple signaling pathways, transcription factors, and effector molecules. The identity of specific genes carrying out these functions is usually determined by single mutant genetic analysis. However, to understand how the individual genes/gene products function, it is necessary to determine how they interact with other components of the larger network; one approach to this is to use genetic interaction analysis. The human fungal pathogen Candida albicans regulates biofilm formation through an interconnected set of transcription factor hubs and is, therefore, an example of this type of complex network...
January 9, 2018: Current Genetics
https://www.readbyqxmd.com/read/29317835/real-world-usage-and-clinical-outcomes-of-alectinib-among-post-crizotinib-progression-anaplastic-lymphoma-kinase-positive-non-small-cell-lung-cancer-patients-in-the-usa
#16
Marco D DiBonaventura, William Wong, Bijal Shah-Manek, Mathias Schulz
Background: Alectinib is an approved treatment for anaplastic lymphoma kinase (ALK)-positive patients with advanced non-small-cell lung cancer. Despite positive supporting clinical data, there is a lack of real-world information on the usage and patient outcomes of those treated with alectinib post-crizotinib progression. Methods: Participating oncologists (N=95) in the USA were recruited from an online physician panel to participate in a retrospective patient chart review...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29317551/characteristics-of-real-world-metastatic-non-small-cell-lung-cancer-patients-treated-with-nivolumab-and-pembrolizumab-during-the-year-following-approval
#17
Sean Khozin, Amy P Abernethy, Nathan C Nussbaum, Jizu Zhi, Melissa D Curtis, Melisa Tucker, Shannon E Lee, David E Light, Anala Gossai, Rachael A Sorg, Aracelis Z Torres, Payal Patel, Gideon Michael Blumenthal, Richard Pazdur
BACKGROUND: Evidence from cancer clinical trials can be difficult to generalize to real-world patient populations, but can be complemented by real-world evidence to optimize personalization of care. Further, real-world usage patterns of programmed cell death protein 1 (PD-1) inhibitors following approval can inform future studies of subpopulations underrepresented in clinical trials. MATERIALS AND METHODS: We performed a multicenter analysis using electronic health record data collected during routine care of patients treated in community cancer care clinics in the Flatiron Health network...
January 9, 2018: Oncologist
https://www.readbyqxmd.com/read/29317333/pocket-size-point-of-care-ultrasound-in-rural-uganda-a-unique-opportunity-to-see-where-no-imaging-facilities-are-available
#18
Danny Epstein, Neta Petersiel, Erez Klein, Erez Marcusohn, Eyal Aviran, Reut Harel, Zaher S Azzam, Ami Neuberger, Lior Fuchs
BACKGROUND: In the developing world, only a small minority of patients have access to radiological services. Over the past decade, technological developments of ultrasound equipment have led to the emergence of point-of-care ultrasonography (POCUS), which is widely used by healthcare professionals of nearly all specialties. We hypothesized that physicians with only basic POCUS training, but with telemedicine support, can use POCUS successfully in rural hospitals in sub-Saharan Africa...
January 6, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29316614/on-the-simulation-based-reliability-of-complex-emergency-logistics-networks-in-post-accident-rescues
#19
Wei Wang, Li Huang, Xuedong Liang
This paper investigates the reliability of complex emergency logistics networks, as reliability is crucial to reducing environmental and public health losses in post-accident emergency rescues. Such networks' statistical characteristics are analyzed first. After the connected reliability and evaluation indices for complex emergency logistics networks are effectively defined, simulation analyses of network reliability are conducted under two different attack modes using a particular emergency logistics network as an example...
January 6, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29315773/mir-451-selectively-increases-sensitivity-to-cisplatin-in-ercc1-high-non-small-cell-lung-cancer-cells
#20
Kaihua Liu, Hong Tian, Yong Zhang, Hao Zhao, Kai Ma
Lung cancer is the leading cause of cancer-related death throughout the world and cisplatin chemoresistance is one of the major hindrances of efficiency in this malignancy therapy. It has been reported that miR-451, a tumor suppressor, is involved in sensitivity of cancer cells to cisplatin. However, the role of miR-451 in chemosensitivity of lung cancer cells and the underlying mechanism still remains to be not fully illuminated. We first assessed the expression of ERCC1 and miR-451 in six NSCLS cell lines and NHBE cells by qRT-PCR...
January 6, 2018: Journal of Cellular Biochemistry
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