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Preoperative anemia

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https://www.readbyqxmd.com/read/29348549/preoperative-anemia-in-colorectal-cancer-relationships-with-tumor-characteristics-systemic-inflammation-and-survival
#1
Juha P Väyrynen, Anne Tuomisto, Sara A Väyrynen, Kai Klintrup, Toni Karhu, Jyrki Mäkelä, Karl-Heinz Herzig, Tuomo J Karttunen, Markus J Mäkinen
Anemia is common in colorectal cancer (CRC) but its relationships with tumor characteristics, systemic inflammation, and survival have not been well characterized. In this study, blood hemoglobin levels and erythrocyte mean corpuscular volume (MCV) levels were measured in two independent cohorts of 148 CRC patients and 208 CRC patients, and their correlation with patient and tumor characteristics, systemic inflammatory markers (modified Glasgow Prognostic Score: mGPS; serum levels of thirteen cytokines, C-reactive protein, albumin), and survival were analyzed...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29341506/impact-of-preoperative-anemia-on-outcomes-in-patients-undergoing-curative-resection-for-gastric-cancer-a-single-institution-retrospective-analysis-of-2163-chinese-patients
#2
Xuechao Liu, Haibo Qiu, Yuying Huang, Dazhi Xu, Wei Li, Yuanfang Li, Yingbo Chen, Zhiwei Zhou, Xiaowei Sun
We sought to evaluate whether preoperative anemia was an important determinant of survival in gastric cancer (GC). A single institution cohort of 2163 GC patients who underwent curative resection were retrospectively analyzed. Anemia was defined as a preoperative hemoglobin level <120 g/L in males and <110 g/L in females. Overall survival (OS) was analyzed using the Kaplan-Meier method, and a multivariate Cox proportional hazards model was performed to identify the independent prognostic factor. Anemic patients had a poorer OS compared with nonanemic patients after resection for tumor-nodes-metastasis (TNM) stage III tumors (5-year OS rate: 32...
January 17, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29326843/risk-of-acute-kidney-injury-in-patients-randomized-to-a-restrictive-versus-liberal-approach-to-red-blood-cell-transfusion-in-cardiac-surgery-a-substudy-protocol-of-the-transfusion-requirements-in-cardiac-surgery-iii-noninferiority-trial
#3
Amit X Garg, Nadine Shehata, Shay McGuinness, Richard Whitlock, Dean Fergusson, Ron Wald, Chirag Parikh, Sean M Bagshaw, Boris Khanykin, Alex Gregory, Summer Syed, Gregory M T Hare, Meaghan S Cuerden, Kevin E Thorpe, Judith Hall, Subodh Verma, Pavel S Roshanov, Jessica M Sontrop, C David Mazer
Background: When safe to do so, avoiding blood transfusions in cardiac surgery can avoid the risk of transfusion-related infections and other complications while protecting a scarce resource and reducing costs. This protocol describes a kidney substudy of the Transfusion Requirements in Cardiac Surgery III (TRICS-III) trial, a multinational noninferiority randomized controlled trial to determine whether the risk of major clinical outcomes in patients undergoing planned cardiac surgery with cardiopulmonary bypass is no greater with a restrictive versus liberal approach to red blood cell transfusion...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29326826/collision-tumor-consisting-of-a-colorectal-adenocarcinoma-and-dissemination-of-a-gastric-adenocarcinoma
#4
Ryoichi Miyamoto, Kazunori Kikuchi, Atsushi Uchida, Masayoshi Ozawa, Akira Kemmochi, Naoki Sano, Sosuke Tadano, Satoshi Inagawa, Shinya Adachi, Masayoshi Yamamoto
Background: Collision tumors, composed of histologically distinct tumor types, are rare entities, especially in the colorectum, and corresponding evidence-based clinical management or treatment strategies are poorly defined. This is the first report of a collision tumor composed of two histologically distinct adenocarcinomas. Case presentation: A 78-year-old male showed severe anemia and a 10% body weight loss over 1 month. Preoperative examination revealed T3N1M0 stage IIIA gastric cancer and T3N0M0 stage IIA rectal cancer...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29322515/current-practices-in-perioperative-blood-management-for-patients-undergoing-liver-resection-a-survey-of-surgeons-and-anesthesiologists
#5
Sean Bennett, Abdul Ayoub, Alexandre Tran, Shane English, Alan Tinmouth, Daniel I McIsaac, Dean Fergusson, Guillaume Martel
BACKGROUND: Development of intraoperative techniques and blood management strategies in liver resection, and the multidisciplinary nature of perioperative transfusion decision making, creates an opportunity for practice variation. The aim of this study was to describe the current practices in perioperative blood management and explore differences between surgeons and anesthesiologists. STUDY DESIGN AND METHODS: A Web-based survey was developed, piloted, and circulated to Canadian liver surgeons and anesthesiologists...
January 10, 2018: Transfusion
https://www.readbyqxmd.com/read/29318944/prevalence-of-iron-deficiency-in-a-total-joint-surgery-population
#6
Jonathan H Waters, Peter Johnson, Mark H Yazer
BACKGROUND: Iron deficiency without anemia has been associated with decreases in functional work capacity and fatigue. The aim of this study was to determine the prevalence of iron deficiency without anemia in a preoperative cohort of orthopedic patients and to determine if iron deficiency is a condition which warrants inclusion into a prehabilitation program prior to surgery. METHODS: One hundred consecutive patients going through preoperative testing for total joint replacement were enrolled in the study...
January 10, 2018: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/29287926/hemoglobin-c-reactive-protein-and-ferritin-in-patients-with-oral-carcinoma-and-their-clinical-significance-a-prospective-clinical-study
#7
Sebastian Blatt, Holger Schön, Keyvan Sagheb, Peer W Kämmerer, Bilal Al-Nawas, Eik Schiegnitz
AIM: For oral squamous cell carcinoma (OSCC), biomarkers are much in need to predict prognosis and to overcome possible resistance mechanisms to adjuvant therapies. The aim of this study was to evaluate serum level of hemoglobin, C-reactive protein (CRP) and ferritin as possible liquid biopsy to predict survival, metastasis and tumor relapse of OSCC. MATERIAL AND METHODS: A prospective clinical study was conducted. Overall, serum levels of hemoglobin, CRP and ferritin in 82 OSCC patients and 63 controls were preoperatively investigated...
December 13, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29279517/the-role-of-double-balloon-enteroscopy-in-the-diagnosis-and-surgical-treatment-of-metastatic-small-bowel-tumors
#8
Naoyuki Nishimura, Motowo Mizuno, Yuichi Shimodate, Akira Doi, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto
Objective The aim of the present study is to investigate the role of double-balloon enteroscopy in the diagnosis and surgical treatment of metastatic small bowel tumors. Patients We retrospectively reviewed the records of 13 patients with metastatic small bowel tumors among 376 patients who underwent double-balloon enteroscopy from June 2005 to March 2017 in our hospital. Results The primary lesion sites were the lung (n=9), kidney (n=2), stomach (n=1) and duodenum (n=1). The clinical presentations were anemia requiring blood transfusion (n=10), obstructive symptoms (n=2), and no symptoms (n=1)...
December 27, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29261547/intravenous-iron-for-treatment-of-anemia-in-the-3-perisurgical-phases-a-review-and-analysis-of-the-current-literature
#9
Frank Peters, Ines Ellermann, Andrea U Steinbicker
Anemia is a common comorbidity throughout the entire hospital stay. Treatment options include intravenous (IV) iron, oral iron, erythropoietin, and red blood cell (RBC) transfusions. IV iron has gained in popularity with the implementation of patient blood management programs. A variety of studies have been performed to investigate the use of IV iron in preoperative, perioperative, and postoperative settings. An objective review on these studies has yet to be performed. The current narrative review provides an overview of trials investigating IV iron use in the preoperative, perioperative, and postoperative settings...
December 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29250797/short-term-effect-of-preoperative-intravenous-iron-therapy-in-colorectal-cancer-patients-with-anemia-results-of-a-cohort-study
#10
Michael Jordi Wilson, Jan Willem Dekker, Emma Bruns, Wernard Borstlap, Johannes Jeekel, Jaap Jan Zwaginga, Martin Schipperus
BACKGROUND: In the treatment of preoperative anemia, which is associated with increased postoperative morbidity, iron supplementation can replace blood transfusion and erythropoiesis-stimulating agents. The aim of this study was to assess the efficacy of preoperative intravenous (IV) iron infusion in optimizing hemoglobin (Hb) levels in anemic colorectal cancer patients. STUDY DESIGN AND METHODS: A retrospective cohort study was performed on patients who underwent surgery for colorectal cancer between 2010 and 2016 in a single teaching hospital...
December 17, 2017: Transfusion
https://www.readbyqxmd.com/read/29245285/perioperative-transfusion-in-pancreatoduodenectomy-the-double-edged-sword-of-pancreatic-surgeons
#11
Hyeong Min Park, Sang-Jae Park, Jae Ryong Shim, Eung Chang Lee, Seung Duk Lee, Sung-Sik Han, Seoung Hoon Kim
We designed the study to clarify the prognostic significance of perioperative (preoperative, intraoperative, and postoperative) red blood cell (RBC) transfusion following pancreaticoduodenectomy (PD) for periampullary cancers.This study retrospectively analyzed 244 periampullary cancer patients (pancreatic cancer, 124 patients; bile duct cancer, 63 patients; and ampullary cancer, 57 patients) treated by PD from June 2001 to June 2010 at the National Cancer Center, Korea (NCC2017-0106).A total of 112 (46%) of 244 patients had received transfusion (preoperative, 5%; intraoperative, 17%; and postoperative, 37%)...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29238644/impact-of-preoperative-anemia-on-outcomes-in-adults-undergoing-elective-posterior-cervical-fusion
#12
Kevin Phan, Alexander E Dunn, Jun S Kim, John Di Capua, Sulaiman Somani, Parth Kothari, Nathan J Lee, Joshua Xu, James E Dowdell, Samuel K Cho
Study Design: Retrospective analysis of prospectively collected data. Objectives: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoperative outcomes following posterior cervical spine fusion. Methods: Data from patients undergoing elective posterior cervical fusions between 2005 and 2012 was collected from the American College of Surgeons National Surgical Quality Improvement Program database using inclusion/exclusion criteria...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29209980/predictors-of-increased-length-of-hospital-stay-following-laparoscopic-sleeve-gastrectomy-from-the-national-surgical-quality-improvement-program
#13
Reid Fletcher, Rebecca Deal, John Kubasiak, Alfonso Torquati, Philip Omotosho
BACKGROUND: Laparoscopic sleeve gastrectomy is the most commonly performed bariatric procedure in the USA. Identifying preoperative risk factors for prolonged postoperative hospital stay will help appropriately select patients for fast-track protocols and avoid costly readmissions. To date, there has been no large national database analysis of risk factors for prolonged length of stay following laparoscopic sleeve gastrectomy. METHODS: Laparoscopic sleeve gastrectomy procedures reported to the American College of Surgeons National Surgical Quality Improvement Program between 2009 and 2012 were reviewed...
December 5, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29199087/primary-total-knee-arthroplasty-for-acute-fracture-around-the-knee
#14
REVIEW
S Parratte, M Ollivier, J-N Argenson
Relatively poor results have been reported with open reduction and internal fixation of complex fractures around the knee in elderly osteoporotic patients, and primary total knee arthroplasty (TKA) has been proposed as an alternative solution. While limiting the number of procedures, it meets two prerequisites: 1) to save the patient's life, thanks to early weight-bearing, to limit decubitus complications; and 2) to save knee function and patient autonomy, thanks to early knee mobilization. There are 3 main indications: complex articular fractures in elderly patients with symptomatic osteoarthritis prior to fracture; complex articular fractures of the tibial plateau in elderly patients whose bone quality makes internal fixation hazardous; and major destruction of the distal femur in younger patients...
November 30, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29176491/impact-of-anemia-and-transfusion-on-readmission-and-length-of-stay-after-spinal-surgery-a-single-center-study-of-1187-operations
#15
Ryan Khanna, Dominic A Harris, Joseph L McDevitt, Richard G Fessler, Louanne M Carabini, Sandi K Lam, Nader S Dahdaleh, Zachary A Smith
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To determine whether receipt of blood transfusion and preoperative anemia are associated with increased rates of 30-day all-cause readmission, and secondarily with a prolonged hospital stay after spinal surgery. SUMMARY OF BACKGROUND DATA: Increased focus on health care quality has led to efforts to determine postsurgical readmission rates and predictors of length of postoperative hospital stay...
December 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29153979/individual-surgeon-practice-is-the-most-important-factor-influencing-diverting-loop-ileostomy-creation-for-patients-undergoing-sigmoid-colectomy-for-diverticulitis
#16
Cigdem Benlice, Conor P Delaney, David Liska, Jennifer Hrabe, Scott Steele, Emre Gorgun
BACKGROUND: To identify factors associated with diverting ileostomy creation (DLI) in patients undergoing sigmoid colectomy for diverticular disease in a high volume colorectal unit and to obtain information for better preoperative patient counseling. METHODS: Patients who underwent sigmoid colectomy with colorectal anastomosis with or without DLI for diverticulitis between 01/1994-12/2014 were identified. Preoperative characteristics, surgeon practice year, individual surgeon and postoperative outcomes were compared between patients with DLI or not...
November 10, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29149910/sodium-chloride-pica-causing-recurrent-nephrolithiasis-in-a-patient-with-iron-deficiency-anemia-a-case-report
#17
Brittany Rogers, Joshua Kramer, Stephanie Smith, Vincent Bird, Eric I Rosenberg
BACKGROUND: Iron deficiency anemia is a common finding in women of child-bearing age. Pica, or the ingestion of non-food or non-nutritive items, is a well-known manifestation of iron deficiency. A high sodium diet increases risk for nephrolithiasis. We describe the case of a 31-year-old woman with recurrent calcium nephrolithiasis and anemia who ate ice chips as well as spoons of salt daily. Treatment of pica may prove effective in preventing recurrent nephrolithiasis. CASE PRESENTATION: A 31-year-old white woman with a past medical history of menorrhagia, anemia, and recurrent calcium nephrolithiasis presented for preoperative evaluation prior to ureterolithotomy...
November 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29143088/the-association-of-preoperative-hematocrit-and-transfusion-with-mortality-in-patients-undergoing-elective-non-cardiac-surgery
#18
Rodney A Gabriel, Anthony I Clark, Albert P Nguyen, Ruth S Waterman, Ulrich H Schmidt
BACKGROUND: Patients with anemia frequently undergo surgery, as it is unclear at what threshold clinicians should consider delaying surgery for preoperative anemia optimization. The primary objective of this study was to determine whether there is an association of varying degrees of anemia and transfusion with 30-day mortality. METHODS: This is a retrospective cohort study using the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2013...
November 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29128046/preoperative-anemia-in-cardiac-operation-does-hemoglobin-tell-the-whole-story
#19
Lu Dai, Stephanie L Mick, Keith R McCrae, Penny L Houghtaling, Joseph F Sabik, Eugene H Blackstone, Colleen G Koch
BACKGROUND: Preoperative anemia, defined by hemoglobin level, is associated with elevated risk after cardiac operation. Better understanding of anemia requires characterization beyond this. This investigation focuses on red cell size and its association with patient characteristics and outcomes after cardiac operation. METHODS: From January 2010 to January 2014, 10,589 patients underwent elective cardiac operations at Cleveland Clinic. Anemia was characterized as normocytic, microcytic, or macrocytic based on mean corpuscular volume (MCV)...
November 8, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29126577/the-efficacy-of-postoperative-iron-therapy-in-improving-clinical-and-patient-centered-outcomes-following-surgery-a-systematic-review-and-meta-analysis
#20
REVIEW
Iris Perelman, Remington Winter, Lindsey Sikora, Guillaume Martel, Elianna Saidenberg, Dean Fergusson
Postoperative anemia is a common occurrence in surgical patients and leads to an increased risk for allogeneic blood transfusions. The efficacy of iron therapy in treating postoperative anemia has not been firmly established. The objective of this systematic review was to evaluate the efficacy of postoperative oral and intravenous (IV) iron therapy in increasing hemoglobin levels and improving patient outcomes following elective surgery. The databases Medline, EMBASE, CENTRAL, the Transfusion Evidence Library, and ClinicalTrials...
October 22, 2017: Transfusion Medicine Reviews
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