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https://www.readbyqxmd.com/read/28431634/multicenter-observational-study-of-abobotulinumtoxina-neurotoxin-in-cervical-dystonia-the-anchor-cd-registry
#1
Richard M Trosch, Alberto J Espay, Daniel Truong, Ramon Gil, Carlos Singer, Peter A LeWitt, Mark F Lew, Michele Tagliati, Charles H Adler, Jack J Chen, Dominic Marchese, Cynthia L Comella
BACKGROUND: The ANCHOR-CD prospective observational registry study evaluated the effectiveness of abobotulinumtoxinA in adult idiopathic cervical dystonia (CD) in clinical practice. METHODS: Adults with CD were eligible. Treating physicians determined abobotulinumtoxinA dose and treatment interval. The primary endpoint was patient response rate (Toronto Western Spasmodic Torticollis Rating Scale [TWSTRS] score reduction≥25% and Patient Global Impression of Change [PGIC] score of +2 or +3 at Week 4 of Cycle 1)...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28428756/neck-circumference-is-associated-with-muscle-sympathetic-nerve-activity-in-overweight-and-obese-men-but-not-women
#2
Nora E Straznicky, Mariee T Grima, Carolina I Sari, Nina Eikelis, Paul J Nestel, John B Dixon, Gavin W Lambert, Markus P Schlaich, Sarah E Phillips, Elisabeth A Lambert
Background: Neck circumference (NC) is a predictor of cardiometabolic risk. The objective of this study was to explore the relationship of NC to muscle sympathetic nerve activity (MSNA) within an overweight and obese population. Methods: The study design was a retrospective cross-sectional analysis. Un-medicated persons (72 men, 53 postmenopausal women) aged 56 ± 1 years (mean ± SEM) with body mass index (BMI) 32.8 ± 0.4 kg/m(2), were studied. NC was measured together with traditional anthropometric measures, supine blood pressure, fasting blood lipids, insulin, and glucose...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28421126/femoral-neck-strain-during-maximal-contraction-of-isolated-hip-spanning-muscle-groups
#3
Saulo Martelli
The aim of the study was to investigate femoral neck strain during maximal isometric contraction of the hip-spanning muscles. The musculoskeletal and the femur finite-element models from an elderly white woman were taken from earlier studies. The hip-spanning muscles were grouped by function in six hip-spanning muscle groups. The peak hip and knee moments in the model were matched to corresponding published measurements of the hip and knee moments during maximal isometric exercises about the hip and the knee in elderly participants...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28416844/clinical-characteristics-of-neurogenic-dysphagia-in-adult-patients-with-chiari-malformation-type-i
#4
T Yu, J Li, K Wang, Y Ge, A C Jiang, L P Duan, Z Y Wang
OBJECTIVE: To investigate changes of swallowing function and associated symptoms in Chiari malformation typeI (CMI) patients with and without dysphagia by the analysis of their clinical and high-resolution manometry (HRM) parameters. METHODS: A total of 42 patients diagnosed with symptomatic CMI without atlantoaxial dislocations which were confirmed by clinical manifestations and magnetic resonance imaging (MRI) findings between January 2010 and July 2015 at Peking University Third Hospital were included in this study...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28415899/specific-muscle-synergies-in-national-elite-female-ice-hockey-players-in-response-to-unexpected-external-perturbation
#5
Minhee Kim, Yushin Kim, Hyeyoung Kim, BumChul Yoon
This study aimed to investigate specific muscle synergies in elite ice hockey players indicating highly developed postural control strategies used to restore balance against unexpected external perturbations. Seven elite athletes (EA) on the women's national ice hockey team and 7 non-athletes (NA) participated in this study. Based on trajectories of centre of mass (COM), analysis periods were divided into an initial phase (a balance disturbance after perturbation onset) and a reversal phase (a balance recovery response), respectively...
April 18, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28414545/modular-use-of-human-body-models-of-varying-levels-of-complexity-validation-of-head-kinematics
#6
William Decker, Bharath Koya, Matthew L Davis, F Scott Gayzik
Objective The significant computational resources required to execute detailed human body finite element models has motivated the development of faster running simplified models (e.g. GHBMC M50-OS). Previous studies have demonstrated the ability to modularly incorporate the validated GHBMC M50-O brain model into the simplified model (GHBMC M50-OS+B), which allows for localized analysis of the brain in a fraction of the computation time required for the detailed model. The objective of this study is to validate the head and neck kinematics of the GHBMC M50-O and M50-OS (detailed and simplified versions of the same model) against human volunteer test data in frontal and lateral loading...
April 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28413557/c2-primary-leiomyoma-in-an-immunocompetent-woman-a-case-report-and-review-of-literature
#7
Mohana Rao Patibandla, Madhukar T Nayak, A K Purohit, Megha Uppin, Sundaram Challa, Gokul Chowdary Addagada, Manisha Nukavarapu
Clinical case report and review of the literature. This is the first case of primary leiomyoma in an immunocompetent woman without previous history of uterine leiomyoma being reported in the literature to the best of our knowledge. Leiomyoma, a type of smooth muscle cell tumor, involving the vertebra is extremely rare. There were very few primary leiomyoma in patients with AIDS or in the immune-suppressed patients. This 48-year-old female came with H/o neck pain, weakness and bladder retention. On examination, tone increased in all four limbs, power on the right side of the limbs 4/5, power on the left upper limb 0/5, lower limb 3/5, left plantar was up going, decreased sensation over the left second cervical vertebra (C2) dermatome and all modalities decreased below C2...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28413118/cadaveric-and-ultrasonographic-validation-of-needling-placement-in-the-cervical-multifidus-muscle
#8
César Fernández-de-Las-Peñas, Juan A Mesa-Jiménez, Jose A Paredes-Mancilla, Shane L Koppenhaver, Samuel Fernández-Carnero
OBJECTIVE: The aim of this study was to determine if a needle is able to reach the cervical multifidus during the application of dry needling or acupuncture. METHODS: Dry needling and ultrasound imaging of cervical multifidi was conducted on 5 patients (age: 32 ± 5 years) with mechanical neck pain and on 2 fresh cadavers (age: 64 ± 1 years). Dry needling was done using a needle of 40 mm in length inserted perpendicular to the skin about 1 cm lateral to the spinous process at C3-C4...
April 13, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28411963/using-a-knowledge-based-planning-solution-to-select-patients-for-proton-therapy
#9
Alexander R Delaney, Max Dahele, Jim P Tol, Ingrid T Kuijper, Ben J Slotman, Wilko F A R Verbakel
BACKGROUND AND PURPOSE: Patient selection for proton therapy by comparing proton/photon treatment plans is time-consuming and prone to bias. RapidPlan™, a knowledge-based-planning solution, uses plan-libraries to model and predict organ-at-risk (OAR) dose-volume-histograms (DVHs). We investigated whether RapidPlan, utilizing an algorithm based only on photon beam characteristics, could generate proton DVH-predictions and whether these could correctly identify patients for proton therapy...
April 12, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28411737/neck-posture-during-lifting-and-its-effect-on-trunk-muscle-activation-and-lumbar-spine-posture
#10
Thomas M Hlavenka, Vanessa F K Christner, Diane E Gregory
Neck and head posture have been found to have a significant influence on the posture of the lower spine region during lifting and both an extended/upward gaze and a flexed/downward gaze have been hypothesized to lead to increased pain and/or overuse of the neck musculature. As a result, strength training recommendations have turned to the use of a retracted neck posture as being the safer posture to assume during lifting. This study examined trunk and neck muscle activity and lumbar spine posture in seven participants while performing moderate load lifts using a retracted neck posture (chin drawn in posteriorly; recently gaining popularity among coaches, trainers, and physical therapists to reduce neck pain during lifting, and freestyle neck posture (no instructions given)...
July 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28411326/neck-muscle-emg-force-relationship-and-its-reliability-during-isometric-contractions
#11
Riccardo Lo Martire, Kristofer Gladh, Anton Westman, Björn O Äng
BACKGROUND: Susceptible to injury, the neck is subject to scientific investigations, frequently aiming to elucidate possible injury mechanisms via surface electromyography (EMG) by indirectly estimating cervical loads. Accurate estimation requires that the EMG-force relationship is known and that its measurement error is quantified. Hence, this study examined the relationship between EMG and isometric force amplitude of the anterior neck (AN), the upper posterior neck (UPN), and the lower posterior neck (LPN) and then assessed the relationships' test-retest reliability across force-percentiles within and between days...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28408276/low-serum-concentrations-of-irisin-are-associated-with-increased-risk-of-hip-fracture-in-chinese-older-women
#12
Jun Yan, Hai-Juan Liu, Wei-Chun Guo, Jian Yang
OBJECTIVE: Irisin derived from muscle in response to exercise may be the molecular entity responsible for muscle wasting-osteoporosis connectivity in the elderly. The objective of the study was to determine whether serum Irisin (sIrisin) provides information on hip fracture prediction which were independent of bone mineral density (BMD) and the fracture risk assessment tool (FRAX) algorithm. METHODS: This study enrolled 160 older women (ages, 70-90 y) with minimal trauma hip fractures (MTHFs) and 160 age-matched women without fracture serving as controls...
April 10, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28405949/transoral-endoscopic-thyroidectomy-preliminary-experience-in-italy
#13
Gianlorenzo Dionigi, Alessandro Bacuzzi, Matteo Lavazza, Davide Inversini, Luigi Boni, Stefano Rausei, Hoon Yub Kim, Angkoon Anuwong
Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a feasible novel surgical procedure that does not need visible incisions. We describe our initial experience with TOETVA. We recruited 15 patients who were willing to undergo TOETVA. Inclusion criteria were (a) patients who had a neck ultrasound (US) with a estimated thyroid diameter not larger than 10 cm; (b) US estimated gland volume ≤45 mL; (c) nodule size ≤50 mm; (d) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter; (e) follicular neoplasm; (f) papillary microcarcinoma without evidence of metastasis...
April 12, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28405219/braided-tape-is-equivalent-to-modified-mason-allen-multi-strand-2-suture-in-subscapularis-muscle-repair-results-of-a-biomechanical-study
#14
Benjamin Léger-St-Jean, Jérémie Ménard, Stéphanie Hinse, Frédéric Balg, Dominique M Rouleau
BACKGROUND: To help determine the optimal fixation method for subscapularis tendon repair in arthroplasty, the present study compares single-passage transosseous tape (BT) and modified Mason-Allen #2 suture (MA). METHODS: Eighteen human cadaveric shoulders were randomized to two repair constructs after arthroplasty preparation. Both techniques included two transosseous passages through the bicipital groove and then through the tendon at the level of the anatomical neck...
April 2017: Shoulder & Elbow
https://www.readbyqxmd.com/read/28401279/current-concepts-in-the-diagnosis-and-management-of-extra-articular-hip-impingement-syndromes
#15
REVIEW
Naoki Nakano, Grace Yip, Vikas Khanduja
PURPOSE: Extra-articular hip impingement syndromes encompass a group of conditions that have previously been an unrecognised source of pain in the hip and on occasion been associated with intra-articular hip impingement as well. As arthroscopic techniques for the hip continue to evolve, the importance of these conditions has been recognised recently and now form an important part of the differential of an individual presenting with hip pain. The aim of this article, therefore, is to provide the reader with an evidence-based and comprehensive update of these syndromes...
April 11, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28399553/rectus-capitis-posterior-minor-histological-and-biomechanical-links-to-the-spinal-dura-mater
#16
Gabriel Venne, Brian J Rasquinha, Manuela Kunz, Randy E Ellis
STUDY DESIGN: Serial histological investigation was performed on 10 cadaveric specimens and biomechanical tests were performed on five specimens, both focused on the tissue connexion between the rectus capitis posterior minor (RCPMi) and the spinal dura. OBJECTIVE: This study had two components: to clarify the microscopic structure of the tissue link between RCPMi and the dura mater, and to evaluate the mechanical role of this tissue complex. SUMMARY OF BACKGROUND DATA: Dissection-based and imaging-based reports have suggested a connective tissue link between the RCPMi and the dura mater at the posterior-atlanto-occipital (PAO) level...
April 15, 2017: Spine
https://www.readbyqxmd.com/read/28399251/association-of-spinal-manipulative-therapy-with-clinical-benefit-and-harm-for-acute-low-back-pain-systematic-review-and-meta-analysis
#17
Neil M Paige, Isomi M Miake-Lye, Marika Suttorp Booth, Jessica M Beroes, Aram S Mardian, Paul Dougherty, Richard Branson, Baron Tang, Sally C Morton, Paul G Shekelle
Importance: Acute low back pain is common and spinal manipulative therapy (SMT) is a treatment option. Randomized clinical trials (RCTs) and meta-analyses have reported different conclusions about the effectiveness of SMT. Objective: To systematically review studies of the effectiveness and harms of SMT for acute (≤6 weeks) low back pain. Data Sources: Search of MEDLINE, Cochrane Database of Systematic Reviews, EMBASE, and Current Nursing and Allied Health Literature from January 1, 2011, through February 6, 2017, as well as identified systematic reviews and RCTs, for RCTs of adults with low back pain treated in ambulatory settings with SMT compared with sham or alternative treatments, and that measured pain or function outcomes for up to 6 weeks...
April 11, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28398951/challenges-in-pathologic-staging-of-bladder-cancer-proposals-for-fresh-approaches-of-assessing-pathologic-stage-in-light-of-recent-studies-and-observations-pertaining-to-bladder-histoanatomic-variances
#18
REVIEW
Gladell P Paner, Rodolfo Montironi, Mahul B Amin
The paradigm of pathologic stage (pT) categorization in bladder cancer remains the depth of invasion into the different histologic layers of the bladder wall. However, the approaches to assigning pT stage category toward an enhanced outcome stratification have been marked by challenges and innovations, due in part to our growing appreciation of the surprisingly perplexing bladder histoanatomy. Upstaging of pT1 tumors after radical cystectomy is substantial and underscores the potential value of pT1 substaging in transurethral resection (TUR) specimens...
May 2017: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/28397021/neck-muscle-moment-arms-obtained-in-vivo-from-mri-effect-of-curved-and-straight-modeled-paths
#19
Bethany L Suderman, Anita N Vasavada
Musculoskeletal models of the cervical spine commonly represent neck muscles with straight paths. However, straight lines do not best represent the natural curvature of muscle paths in the neck, because the paths are constrained by bone and soft tissue. The purpose of this study was to estimate moment arms of curved and straight neck muscle paths using different moment arm calculation methods: tendon excursion, geometric, and effective torque. Curved and straight muscle paths were defined for two subject-specific cervical spine models derived from in vivo magnetic resonance images (MRI)...
April 10, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28394862/the-facial-platysma-and-its-underappreciated-role-in-lower-face-dynamics-and-contour
#20
Ada R T de Almeida, Alessandra Romiti, Jean D A Carruthers
BACKGROUND: The platysma is a superficial muscle involved in important features of the aging neck. Vertical bands, horizontal lines, and loss of lower face contour are effectively treated with botulinum toxin A (BoNT-A). However, its pars facialis, mandibularis, and modiolaris have been underappreciated. OBJECTIVE: To demonstrate the role of BoNT-A treatment of the upper platysma and its impact on lower face dynamics and contour. MATERIAL AND METHODS: Retrospective analysis of cases treated by an injection pattern encompassing the facial platysma components, aiming to block the lower face as a whole complex...
April 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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