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https://www.readbyqxmd.com/read/28210634/potential-of-a-pharmacogenetic-guided-algorithm-to-predict-optimal-warfarin-dosing-in-a-high-risk-hispanic-patient-role-of-a-novel-nqo1-2-polymorphism
#1
Dagmar F Hernandez-Suarez, Karla Claudio-Campos, Javier E Mirabal-Arroyo, Bianca A Torres-Hernández, Angel López-Candales, Kyle Melin, Jorge Duconge
Deep abdominal vein thrombosis is extremely rare among thrombotic events secondary to the use of contraceptives. A case to illustrate the clinical utility of ethno-specific pharmacogenetic testing in warfarin management of a Hispanic patient is reported. A 37-year-old Hispanic Puerto Rican, non-gravid female with past medical history of abnormal uterine bleeding on hormonal contraceptive therapy was evaluated for abdominal pain. Physical exam was remarkable for unspecific diffuse abdominal tenderness, and general initial laboratory results-including coagulation parameters-were unremarkable...
October 2016: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28205124/routine-radiologic-contrast-agent-examination-after-gastrectomy-for-gastric-cancer-is-not-useful
#2
Benjamin Struecker, Sascha Chopra, Ann-Christin Heilmann, Johanna Spenke, Christian Denecke, Igor M Sauer, Marcus Bahra, Johann Pratschke, Andreas Andreou, Matthias Biebl
Many studies have showed that routine upper gastrointestinal contrast agent examinations (RCE) for testing the patency of the anastomosis after esophagectomy or the stapler line after sleeve gastrectomy cannot be recommended due to low sensitivity. However, the clinical value of RCE after gastrectomy for gastric cancer remains unclear. We have retrospectively analyzed the clinical course of 377 consecutive patients who underwent gastrectomy for gastric cancer in our institution between 2005 and 2015. To date, we have performed a RCE on the fifth postoperative day before removal of the nasogastric tube and return to oral intake...
February 15, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28202862/venous-thromboembolism-due-to-oral-contraceptive-intake-and-spending-nights-in-a-vehicle-a-case-from-the-2016-kumamoto-earthquakes
#3
Daisuke Sueta, Rika Akahoshi, Yoshinori Okamura, Sunao Kojima, Tomokazu Ikemoto, Eiichiro Yamamoto, Yasuhiro Izumiya, Kenichi Tsujita, Koichi Kaikita, Hidetaka Katabuchi, Seiji Hokimoto
A 40-year-old woman experiencing sudden dyspnea went to her personal doctor for advice. She was previously diagnosed with endometriosis and prescribed oral contraceptives for treatment. During earthquakes, she spent 7 nights sleeping in a vehicle. The patient had swelling and pain in her left leg and high D-dimer concentration levels. A contrast-enhanced computed tomography scan revealed a contrast deficit in the bilateral pulmonary artery and in the left lower extremity. She was diagnosed with pulmonary thromboembolism (PTE), and anticoagulation therapy was initiated...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28176914/upward-migration-of-a-ureteric-stone-in-a-military-trainer-a-case-report
#4
Moayid Fallatah, Sakher Tahaineh, Rawan Abu Mughli, Seddig M Fallatah
Retrograde ureteric stone migration is an extremely rare phenomenon with only one previously reported case in the literature. We report on a case of upward spontaneous migration of a ureteric stone in a 39-year-old male military trainer in Saudi Arabia who was diagnosed with upper left ureteric stone based on non-contrast spiral computerized tomography kidney ureter bladder (CT-KUB) scan. The plan was to treat the patient conservatively with alpha blockers and oral hydration. Two weeks after treatment started, repeated CT-KUB scan revealed an upward migration of the stone to the left renal calyx...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/28163657/successful-treatment-of-deep-vein-thrombosis-caused-by-iliac-vein-compression-syndrome-with-a-single-dose-direct-oral-anti-coagulant
#5
Naoya Nakashima, Daisuke Sueta, Yusuke Kanemaru, Seiji Takashio, Eiichiro Yamamoto, Shinsuke Hanatani, Hisanori Kanazawa, Yasuhiro Izumiya, Sunao Kojima, Koichi Kaikita, Seiji Hokimoto, Kenichi Tsujita
BACKGROUND: Although vein stenting is popular for treatment for venous thromboembolism due to mechanical compression, some cases are forced to avoid inserting align agents because of immunodeficiency. CASE PRESENTATION: An 82-year-old man with left extremity redness and swelling presented to a hospital for a medical evaluation. The patient was immunodeficient because of the adverse effects of his treatment for Castleman's disease. A contrast-enhanced computed tomography scan revealed a venous thromboembolism in inferior vena cava and the left lower extremity...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28133232/-a-case-of-metachronous-liver-metastases-of-gall-bladder-cancer-successfully-treated-by-liver-resection
#6
Kensuke Asai, Masaru Murata, Kazuhiro Saso, Moyuru Yamada, Hirokazu Sawami, Rei Suzuki, Hiroki Fukunaga, Nobuo Tanaka, Masayuki Yamamoto, Masahiro Hiratsuka
A 73-year-old woman was diagnosed with gall bladder cancer by contrast enhanced CT images.The tumor was detected at the fundus of the gall bladder and enhanced heterogeneously.She underwent radical cholecystectomy including Japanese D2 lymph node dissection for gall bladder cancer.After 4 courses of oral S-1(80mg/m2 administered for 4 weeks and then stopped for 2 weeks)as adjuvant chemotherapy, a liver metastasis at segment 5 appeared 11 months postoperatively.It showed a ring enhanced tumor on contrast enhanced CT images...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133141/-a-case-of-aortoesophageal-fistula-rupture-due-to-descending-thoracic-aortic-dissection-with-recurrent-colon-cancer-during-chemotherapy-containing-bevacizumab
#7
Takamaru Koda, Junichi Koike, Hiroshi Masuhara, Akiharu Kurihara, Hiroyuki Shiokawa, Mitsunori Ushigome, Tomoaki Kaneko, Takayuki Suzuki, Yuko Sawaguchi, Tomoyuki Katayanagi, Takerou Fujii, Yoshinori Watanabe, Kimihiko Funahashi, Hideaki Shimada, Hironori Kaneko
We report a case of aortoesophageal fistula rupture during the course of chemotherapy following colon cancer resection. The patient was a 77-year-old woman. Following recurrence of cancer of the sigmoid colon, the patient received a course of XELOX plus bevacizumab(Bmab)to treat peritoneal dissemination and lung metastases. She was brought by ambulance to our hospital's emergency department 55 days after the last dose of Bmab, with a chief complaint of hematemesis. Hematolo- gy results showed severe anemia with a hemoglobin level of 4...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28091837/peritoneal-fluid-of-low-ct-hounsfield-units-as-a-screening-criterion-for-traumatic-bowel-perforation
#8
Yon-Cheong Wong, Li-Jen Wang, Cheng-Hsien Wu, Huan-Wu Chen, Being-Chuan Lin, Yu-Pao Hsu
PURPOSE: To investigate whether peritoneal fluid of low CT Hounsfield units is an important screening criterion for traumatic bowel perforation. MATERIALS AND METHODS: We performed a retrospective study on two cohorts of blunt trauma patients who had peritoneal fluid. Intravenous and oral contrast was used for the first cohort (61 patients) as opposed to intravenous contrast only for the second cohort (60 patients). We compared the CT Hounsfield units of peritoneal fluid with bowel perforation...
January 13, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28087955/water-as-neutral-oral-contrast-agent-in-abdominopelvic-ct-comparing-effectiveness-with-gastrografin-in-the-same-patient
#9
C H Lee, H Z Gu, B A Vellayappan, C H Tan
INTRODUCTION: Positive oral contrast is no longer deemed necessary for abdominopelvic computed tomography (CT) scans. Studies have shown water to be an equally effective oral contrast agent. However, to our knowledge no study has compared effectiveness between gastrografin and water in the same patient, which will provide a more objective evaluation of the two oral contrast agents. We aim to make a head-to-head comparison of water as neutral oral contrast (OC) against gastrografin as positive OC for abdominopelvic CT scans in the same patient...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28087066/use-of-water-soluble-contrast-medium-gastrografin-does-not-decrease-the-need-for-operative-intervention-nor-the-duration-of-hospital-stay-in-uncomplicated-acute-adhesive-small-bowel-obstruction-a-multicenter-randomized-clinical-trial-adhesive-small-bowel-obstruction
#10
Michel Scotté, Francois Mauvais, Michael Bubenheim, Cyril Cossé, Leslie Suaud, Celine Savoye-Collet, Isabelle Plenier, Aurelien Péquignot, Thierry Yzet, Jean Marc Regimbeau
BACKGROUND: This study evaluated the association between oral gastrografin administration and the need for operative intervention in patients with presumed adhesive small bowel obstruction. METHODS: Between October 2006 and August 2009, 242 patients with uncomplicated acute adhesive small bowel obstruction were included in a randomized, controlled trial (the Adhesive Small Bowel Obstruction Study, NCT00389116) and allocated to a gastrografin arm or a saline solution arm...
January 10, 2017: Surgery
https://www.readbyqxmd.com/read/28057367/increased-pre-procedural-urinary-microalbumin-is-associated-with-a-risk-for-renal-functional-deterioration-after-coronary-computed-tomography-angiography
#11
Satoshi Isobe, Miyuki Yuba, Hiroaki Mori, Susumu Suzuki, Kimihide Sato, Hideki Ishii, Toyoaki Murohara
BACKGROUND: Urinary microalbumin is a marker for preclinical nephropathy. A percentage change in cystatin C (%CyC) of ≥10% for 24h after tests with contrast media is reportedly an independent predictor for developing contrast-induced nephropathy. We investigated the relationship between the presence of urinary microalbumin and changes in CyC after coronary computed tomography angiography (CCTA). METHODS: Three hundred and thirty-three patients with known or suspected coronary artery disease who scheduled for CCTA using a 70mL of Iopamidol were enrolled...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28048915/su-f-i-29-investigating-the-impact-of-the-amount-of-contrast-material-used-in-abdominal-ct-examinations-regarding-the-diagnosis-of-appendicolith
#12
E Lavdas, N Boci, L Sarantaenna, A Godevenos, I Ntavelis, T Theodoropoulos, G Zaimis, P Mavroidis
PURPOSE: The purpose of this study is to report the case of a young adult in which the incomplete oral administration of contrast material led to diagnosis of an appendicolith, which cause acute appendicitis. METHODS: A male 34 years old underwent CT examination due to acute abdominal pain in the upper abdomen. An ultrasound examination of the upper abdomen and kidneys, an x-ray examination of the abdomen and a CT scan of the entire abdomen and pelvis after both oral and IV administration of contrast material were performed...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047012/we-fg-207b-01-best-in-physics-imaging-abdominal-ct-with-three-k-edge-contrast-materials-using-a-whole-body-photon-counting-scanner-initial-results-of-a-large-animal-experiment
#13
M Lakshmanan, R Symons, T Cork, C Davies-Venn, K Rice, A Malayeri, V Sandfort, D Bluemke, A Pourmorteza
PURPOSE: To demonstrate the feasibility of in vivo three-material decomposition techniques using photon-counting CT (PCCT) with possible advantage of resolving arterial and venous flow of an organ simultaneously. METHODS: Abdominal PCCT scans were acquired using a prototype whole-body PCCT with four energy thresholds (25/50/75/90keV) in a canine. Bismuth subsalicylate (60 mg) was administered orally one day prior to scanning. Immediately prior to CT scan, gadoteric acid (60 ml, Dotarem, Guerbet) was intravenously injected, followed in ten minutes by a 20mL injection of iodinated contrast (iopamidol 370 mg/mL, Bracco)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046275/su-f-p-29-impact-of-oral-contrast-agent-for-assisting-in-outlining-small-intestine-on-pelvic-imat-dose-in-patients-with-cervical-cancer
#14
R Zhang, W Bai, X Fan
PURPOSE: As the advanced intensity modulated arc therapy(IMAT) delivery systems becoming a main role of treatment ways, which places even greater demands on delivering accuracy. The impact of oral contrast agent (meglumine diatrizoate) for assisting in outlining the small intestine on pelvic IMAT dose in patients with cervical cancer was investigated. METHODS: Ten cervical cancer patients for postoperative radiotherapy underwent CT scans, and the planning target volumes (PTV) and organs at risk (including the small intestine, rectum, bladder, colon and the left and right femoral head) were contoured...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025476/a-case-of-hepatocellular-carcinoma-presenting-as-a-gingival-mass
#15
Min Jung Kwon, Soo Hyung Ryu, Soo Yeon Jo, Chul Hoon Kwak, Won Jae Yoon, Jeong Seop Moon, Hye Kyung Lee
Oral metastatic tumor, which is uncommon and represents less than 1% of malignant oral neoplasms, usually arises from a primary mucosal or cutaneous cancer located in the head and neck regions. Metastasis of hepatocellular carcinoma (HCC) to the oral cavity, especially to gingiva, is extremely rare. A 50-year-old man, who was a chronic alcoholic and hepatitis B virus carrier, presented with abdominal distension and weight loss for the past 3 months. Three-phased contrast-enhanced abdominal CT revealed numerous conglomerated masses in the liver, suggesting huge HCCs arising in the background of liver cirrhosis with a large amount of ascites...
December 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28011496/identification-and-management-of-head-and-neck-cancer-recurrences-detected-on-adjuvant-radiation-oncology-simulation-scans
#16
Richard L Bakst, William Su
BACKGROUND/AIM: Computerized tomographic (CT) simulation is used to design precise radiation therapy treatment plans. These scans are not routinely read by radiology and are only used for planning purposes. As radiation oncology departments adopt the addition of intravenous contrast to their CT simulations, there is the potential for identification of post-surgical recurrences. PATIENTS AND METHODS: We identified all biopsy-proven local recurrences of head and neck cancer detected during CT simulation and followed their outcomes...
2017: Anticancer Research
https://www.readbyqxmd.com/read/27933477/impact-of-low-energy-ct-imaging-on-selection-of-positive-oral-contrast-media-concentration
#17
Manuel Patino, Diana J Murcia, Andrea Prochowski Iamurri, Avinash R Kambadakone, Peter F Hahn, Dushyant V Sahani
OBJECTIVES: To determine to what extent low-energy CT imaging affects attenuation of gastrointestinal tract (GIT) opacified with positive oral contrast media (OCM). Second, to establish optimal OCM concentrations for low-energy diagnostic CT exams. METHODS: One hundred patients (38 men and 62 women; age 62 ± 11 years; BMI 26 ± 5) with positive OCM-enhanced 120-kVp single-energy CT (SECT), and follow-up 100-kVp acquisitions (group A; n = 50), or 40-70-keV reconstructions from rapid kV switching-single-source dual-energy CT (ssDECT) (group B; n = 50) were included...
December 8, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27933409/imaging-trends-in-suspected-appendicitis-a-canadian-perspective
#18
Victoria F Tan, Michael N Patlas, Douglas S Katz
PURPOSE: The purpose of our study was to assess trends in the imaging of suspected appendicitis in adult patients in emergency departments of academic centers in Canada. METHODS: A questionnaire was sent to all 17 academic centers in Canada to be completed by a radiologist who works in emergency radiology. The questionnaires were sent and collected over a period of 4 months from October 2015 to February 2016. RESULTS: Sixteen centers (94%) responded to the questionnaire...
December 8, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27917278/the-preventive-and-therapeutic-roles-of-phytoestrogen-%C3%AE-zearalanol-on-osteoporetic-rats-due-to-ovariectomization
#19
Shaochun Li, Weiwei Zhang, Fei Duan, Weihua Liu, Xiaofang Sun, Xuefeng Pan
OBJECTIVES: The aim of this study was to observe the influence of phytoestrogen α-Zearalanol on ovariectomy-induced postmenopausal osteoporosis in rats. MATERIALS AND METHODS: 40 SD female rats were randomly divided into four groups: Sham group, OVX group (ovariectomized and fed estrogen), α-Zearalanol group (ovariectomized and fed α-Zearalanol) and untreated group (ovariectomized). Three weeks later after surgery, α-Zearalanol and estradiol valerate were administered by oral gavage for 12 weeks to the α-Zearalanol group and the OVX group, respectively...
November 2016: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/27908546/effects-of-branched-chain-amino-acid-supplementation-after-radiofrequency-ablation-for-hepatocellular-carcinoma-a-randomized-trial
#20
Shunsuke Nojiri, Kei Fujiwara, Noboru Shinkai, Etsuko Iio, Takashi Joh
OBJECTIVE: Maintenance of liver function is important for better outcomes after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). The aim of this study was to examine the effects of oral branched-chain amino acid (BCAA) supplementation on liver function, intrahepatic recurrence rate, and incidence of complications after RFA for HCC. METHODS: Patients with cirrhosis who underwent RFA were enrolled between August 2009 and April 2012, randomized to oral supplementation with Aminoleban EN (BCAA group) or diet alone (control group), and followed to determine changes in serum parameters and health status...
January 2017: Nutrition
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