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Systemic desease

Dafne Braga Diamante Leiderman, Nelson Wolosker, Marcos Vieira de Melo Oliveira, Heitor Andrei Miranda de Carvalho, Felipe Trajano de Freitas Barão, Antonio Eduardo Zerati, Nelson De Luccia, Pedro Puech-Leão
BACKGROUND: Transient paraplegia of the lower limbs is a rare condition and, when has a vascular etiology, is usually associated with thromboembolic events, aortic dissection, aortic aneurysms, or as a complication of the surgical correction of those diseases. There is no case reported of acute paraplegia caused by a segmental thrombotic subocclusion of the descending thoracic aorta. CASE REPORT: We report a not yet described clinical situation of a young patient (51 years) admitted to the emergency care department for treatment of systemic arterial hypertension of difficult control with 4 antihypertensive medication classes...
March 5, 2018: Annals of Vascular Surgery
Mariia Nagalievska, Mariya Sabadashka, Halyna Hachkova, Nataliia Sybirna
BACKGROUND: An impaired leukocytes function is the factor causing the susceptibility of patients with diabetes mellitus to infections. The outmost importance for the understanding of the immunological processes involved in diabetes pathogenesis is to give the characteritics of the immunological profile and changes therein, during the course of desease. Long-used in folk medicine to treat diabetes Galega officinalis L. has been chosen for the correction of the immune system dysfunction...
January 8, 2018: BMC Complementary and Alternative Medicine
Justus G Garweg, Souska Zandi, Isabel B Pfister, Magdalena Skowronska, Christin Gerhardt
PURPOSE: To compare the cyto- and chemokine profiles in the aqueous humor of PEXS eyes in the absence or presence of secondary glaucoma with or without luxation of the intraocular lens (IOL). METHODS: Samples of aqueous humor were collected intraoperatively from 20 healthy controls and from 73 eyes with PEX-syndrome, which was manifested in the absence of any other local or systemic desease. The latter group was sub-devided into eyes with an early form of PEX-syndrome in the absence of complications (PEX, n = 33), those with a late form of PEX-syndrome and glaucoma (PEXG, n = 30), and those with a late form of PEX-syndrome with luxation of the IOL that required surgery (PEXL, n = 10)...
2017: PloS One
Magdalena Madero, Fernando E García-Arroyo, Laura-Gabriela Sánchez-Lozada
PURPOSE OF REVIEW: Mesoamerican nephropathy (MeN) is an emerging pathophysiological entity of Chronic kidney desease (CKD) not related to traditional risk factors (diabetes and hypertension) that have caused thousands of deaths in Central America, mainly in sugarcane workers. The focus of this review is to discuss the risk factors and probable mechanisms involved in the initiation and progression of this devastating disease. RECENT FINDINGS: Frequent episodes of subclinical Acute kidney injury caused by repetitive heat stress, dehydration, and strenuous work have been regarded as the main risk factors for MeN...
July 2017: Current Opinion in Nephrology and Hypertension
Chao-Yang DU, Ru-Yu Yang, Chao Li, Li-Juan Duan
OBJECTIVE: To study the clinical features of of patients with primary central nervous system lymphoma(PCNSL) and their influence on prognosis. METHODS: Forty-two cases of PCNSL hospitallized in our hospital from January 2012 to December 2015 were selected, and the laboratory analysis, imaging examination, bone marrow analysis and pathological examination all were performed, 26 cases were treated by lumbar puncture combined with intrathecal injection of drugs (Ara C, dexamethason and methotrexate), 8 cases were treated by methotrexate combined with rituximab, 8 cases voluntanly abandon treatment after being diagnosed as PCNSL...
December 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
S V Shevchuk, L P Denyschych
The article presents data on levels of osteocalcin and pyridinoline in patients with systemic lupus erythematosus (SLE), their comparison with structural and functional state of bone tissue and course of the disease. Bone metabolism derangements were found in 65.8% of women with SLE. Herewith, the increase of pyridinoline content was observed in 43.9% of patients, the reduction of osteocalcinin 39% of individuals. The deterioration of bone metabolism was associated with the severity of the disease, especially high levels of C-reactive protein (CRP) and interleukin-6 (IL-6) (r = 0...
October 2015: Likars'ka Sprava
Faizan Anwer, Savita Chaurasia, Abid Ali Khan
After the Second World War, infatuation with modern products has exponentially widened the spectrum of chemicals used. Some of them are capable of hijacking the endocrine system by blocking or imitating a hormone and are referred to as hormonally active chemicals or endocrine disruptors. These are chemicals that the body was not designed for evolutionarily and they are present in every matrix of the environment. We are living in a chemical world where the exposures are ubiquitous and take place in combinations that can interact with the endocrine system and some other metabolic activities in unexpected ways...
December 1, 2016: Reviews on Environmental Health
Daniela Ferreira, Ana M L Seca, Diana C G A, Artur M S Silva
UNLABELLED: Human bacterial infections are still a major public health problem throughout the world. Therefore it is fundamental to understand how pathogenic bacteria interact with their human host and to develop more advanced drugs or vaccines in response to the increasing bacterial resistance. Since iron is essential to bacterial survival and growth inside the host tissues, these microorganisms have developed highly efficient iron-acquisition systems; the most common one involves the secretion of iron chelators into the extracellular environment, known as siderophores, and the corresponding siderophore-membrane receptors or transporters responsible for the iron uptake...
August 11, 2016: Journal of Proteomics
Paolo Di Benedetto, Giuseppe Niccoli, Alessandro Beltrame, Renato Gisonni, Vanni Cainero, Araldo Causero
BACKGROUND: The pathogenesis of non traumatic osteonecrosis of the femoral head (ONFH) has not yet been established. The literature shows a variable nomenclatura for this condition that often leads to confusion. Several risk factors have been identified but histopathological and radiological outcomes are common. PURPOSE: To provide the overview on the current knowledges about the nomenclatura, etiology, disease progression, relationship between histopathological changes and imaging techniques in order to stage the disease accurately...
April 15, 2016: Acta Bio-medica: Atenei Parmensis
Qing-hua Wang, Wen-jie Shang, Chun-tao Zhao, Shu-wen Zhang, Shou-long Lu, Xiao-dong Liu
OBJECTIVE: To investigate the prevalence of echinococcosis in Gannan Tibetan Autonomous Prefecture of Gansu Province since the implementation of the echinococcosis control project from Sepical Funds for Central Government Subsidies to Local Public Health (2007-2011). METHODS: Eight counties of Hezuo, Lintan, Zhuoni, Luqu, Maqu, Xiahe, Zhouqu, and Diebu were selected as survey sites. The prevalence in the sampled population was investigated by B ultrasound examination...
February 2015: chinese Journal of Parasitology & Parasitic Diseases
N G Grushka, S I Pavlovych, T M Bryzgina, V S Sukhina, N V Makogon, R I Yanchiy
There were performed the studies of genotoxic stress and the ways of immunocompetent cells death (apoptosis and necrosis) in the modeling of immune system damage by immunization of CBA mice with the bovine serum albumin. Immunofluorescence studies of immunized mice were established the fixation of immune complexes in liver tissue, spleen, kidney and the aorta. Histological studies of these organs showed vascular system affection and, to a lesser extent, parenchyma. It has been shown that DNA comets index increases in 1,4 time in the lymph node cells and in 1,5 time in the thymus cells in the presence of BSA immunization...
2015: Fiziolohichnyĭ Zhurnal
Tomasz Nitoń, Aleksandra Górecka-Nitoń
Acute appendicitis (AA) is the cause one of most operations perform in department of general surgery on emergency ward. Frequency of acute appendicitis range from 6-8% of population. Clinical presentation is frequently unspecified and despite common occurence leads to many difficulties in diagnosis. Diagnosis of acute appendicitis includes clinical examination, laboratory tests, diagnostic scoring systems, computer programs as physisian aids and imaging examinations. About 30-45% patients suspected of acute appendicitis have untypical clinical presentation and here use of US or CT is very helpful...
2014: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
D A Morozov, E S Pimenova, V K Tatochenko, M D Bakradze, D D Gadliya, O L Morozova, A G Talalaev
The rare combination of intestinal lymphangiectasia with malrotation of the duodenum in a child of three months of life is described. Basing on the literature review only 3 similar cases were described in the world practice. The boy with protein-losing enteropathy was examined at Moscow Scientific Centre of Children's Health. The child had vomiting, diarrhea, loss in body weight, hypoproteinemia, lymphopenia. The infectious nature of the disease was excluded. It had been suggested the Waldman desease (primary intestinal lymphangiectasia)...
2015: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Leonardo López, Germán Burguerner, Leonardo Giovanini
BACKGROUND: The spread of an infectious disease is determined by biological and social factors. Models based on cellular automata are adequate to describe such natural systems consisting of a massive collection of simple interacting objects. They characterize the time evolution of the global system as the emergent behaviour resulting from the interaction of the objects, whose behaviour is defined through a set of simple rules that encode the individual behaviour and the transmission dynamic...
2014: BMC Research Notes
O V Dolynna
It is set that in 26.9% patients with coronary desease there are the depressed disorders. The easy degree of depression was observed in 61.1% persons, maskable depression--in 27.8% persons, middle degree of depression--in 11.1% persons. For such patients the decline of heart rhythm variability, increase of sympathetic tone, violation of day's rhythm of vegetative nervous system, prevalence of humoral influence on a heart rhythm were revealed.
July 2013: Likars'ka Sprava
Olivera Sarakinova, Mile Carcev, Biljana Getova, Sofija Carceva Salja, Sevdalina Janevska
Human principles and the fundamental values are the main principles stipulated in the Constitution of Republic of Macedonia. The Government of the Republic of Macedonia, within its program objectives, implementing the laws in the country, the international standards and the global health care as the worlds objective of the Constitution of WHO. According to the information received through the health monitoring system, as well as the results from target and selective studies, they have shown that the condition of oral health, especially the condition with the dental caries is serious health problem of all groups...
2013: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
N B Korsantiia, X T Davarashvili, L E Gogiashvili, M T Mamaladze, Z G Tsagareli, E B Melikadze
The aim of study is the analysis of pulp nerve fibers demyelination degree and its relationship with Visual Analogue Scale (VAS) score that may be measured as objective criteria. Material and methods of study. Step I: electron micrografs of dental pulp simples with special interest of myelin structural changes detected in 3 scores system, obtained from 80 patients, displays in 4 groups: 1) acute and 2) chronic pulpitis without and with accompined systemic deseases, 20 patients in each group. Dental care was realized in Kutaisi N1 Dental clinic...
May 2013: Georgian Medical News
Xu Wang, Ross Sager, Weier Cui, Chong Zhang, Hua Lu, Jung-Youn Lee
In plants, mounting an effective innate immune strategy against microbial pathogens involves triggering local cell death within infected cells as well as boosting the immunity of the uninfected neighboring and systemically located cells. Although not much is known about this, it is evident that well-coordinated cell-cell signaling is critical in this process to confine infection to local tissue while allowing for the spread of systemic immune signals throughout the whole plant. In support of this notion, direct cell-to-cell communication was recently found to play a crucial role in plant defense...
June 2013: Plant Cell
N Mylonas, C Damianou
BACKGROUND: A prototype magnetic resonance imaging (MRI)-compatible positioning device that navigates a high intensity focused ultrasound (HIFU) transducer is presented. The positioning device has three user-controlled degrees of freedom that allow access to brain targets using a lateral coupling approach. The positioning device can be used for the treatment of brain cancer (thermal mode ultrasound) or ischemic stroke (mechanical mode ultrasound). MATERIALS AND METHODS: The positioning device incorporates only MRI compatible materials such as piezoelectric motors, ABS plastic, brass screws, and brass rack and pinion...
March 2014: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
Piffaretti, Haefliger
Lidedema can be a common symptom of diseases of the orbital part of the face. One can differentiate lidedema in two groups, those that are related to an inflammation and those that are not related to an inflammation. Lidedema of the eyelid can also be secondary to a systemic desease. There is also another group that is common in the ageing population that consists of blepharochalasis and dermatochalasis where the skin becomes loose with the years and forms redundant folds.
November 1, 2004: Therapeutische Umschau. Revue Thérapeutique
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