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https://www.readbyqxmd.com/read/29651665/evaluation-and-management-of-thromboprophylaxis-in-moroccan-hospitals-at-national-level-the-avail-mona-study
#1
Z Tazi Mezalek, C Nejjari, L Essadouni, M Samkaoui, K Serraj, W Ammouri, N Kanjaa, Z Belkhadir, B Housni, M Awab, M Faroudy, W Bono, S Kabbaj, M Akkaoui, M Barakat, R Rifai, H Charaf, A Aziz, Y Elachhab, A Azzouzi
Venous thromboembolism (VTE) is a common clinical problem that is associated with substantial morbidity and mortality. The aim of this study was to describe the clinical practices in VTE prophylaxis in university and peripheral hospitals in Morocco. This is a national, cross-sectional, multicenter, observational study assessing the management of the VTE risk in selected Moroccan hospitals (four university and three peripheral). The thromboembolic risk of the selected patients was assessed according to the American College of Chest Physicians (ACCP) guidelines (2008)...
April 12, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29649767/heparin-induced-thrombocytopenia-a-critical-appraisal-of-clinical-practice-guidelines-with-the-agree-ii-instrument
#2
Ying Wang, Zhi-Kang Ye, Ji-Feng Li, Xiang-Li Cui, Li-Hong Liu
BACKGROUND: Despite the availability of clinical practice guidelines (CPGs), the risk of death or thromboembolic complication associated with heparin-induced thrombocytopenia (HIT) remains high. Our aim was to systematically review the quality of CPGs for HIT and summarize the recommendations. METHODS: CPGs for HIT were systematically searched on PubMed, Embase, guidelines' websites, and Google up to August 6, 2017. Independently, three appraisers assessed the quality of CPGs using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) instrument and extracted the data...
March 27, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29584756/transcriptional-signature-associated-with-early-rheumatoid-arthritis-and-healthy-individuals-at-high-risk-to-develop-the-disease
#3
N Macías-Segura, J E Castañeda-Delgado, Y Bastian, D Santiago-Algarra, J D Castillo-Ortiz, A L Alemán-Navarro, E Jaime-Sánchez, M Gomez-Moreno, C A Saucedo-Toral, Edgar E Lara-Ramírez, M Zapata-Zuñiga, L Enciso-Moreno, R González-Amaro, C Ramos-Remus, J A Enciso-Moreno
BACKGROUND: Little is known regarding the mechanisms underlying the loss of tolerance in the early and preclinical stages of autoimmune diseases. The aim of this work was to identify the transcriptional profile and signaling pathways associated to non-treated early rheumatoid arthritis (RA) and subjects at high risk. Several biomarker candidates for early RA are proposed. METHODS: Whole blood total RNA was obtained from non-treated early RA patients with <1 year of evolution as well as from healthy first-degree relatives of patients with RA (FDR) classified as ACCP+ and ACCP- according to their antibodies serum levels against cyclic citrullinated peptides...
2018: PloS One
https://www.readbyqxmd.com/read/29541435/prophylaxis-against-deep-venous-thrombosis-in-patients-hospitalized-in-surgical-wards-in-one-of-the-hospitals-in-iran-based-on-the-american-college-of-chest-physician-s-protocol
#4
Masoumeh Shohani, Akram Mansouri, Siros Norozi, Naser Parizad, Milad Azami
Background: There is not enough studies to determine the frequency of using the prophylaxis against deep venous thrombosis (DVT) based on the American College of Chest Physician's (ACCP) guidelines in Iran. Thus, providing such statistics is essential to improve thromboprophylaxis in hospital. The present study aimed to determine the frequency of using the prophylaxis against DVT based on ACCP guidelines in patients hospitalized in surgical wards in one of teaching hospital in Ilam, Iran...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29484515/early-stage-non-small-cell-lung-cancer-patients-need-brain-imaging-regardless-of-symptoms
#5
Takahiro Ando, Hidenori Kage, Minako Saito, Yosuke Amano, Yasushi Goto, Jun Nakajima, Takahide Nagase
BACKGROUND: Japanese Lung Cancer Society and ESMO guideline recommends screening for brain metastasis in all patients with non-small cell lung cancer (NSCLC), while NCCN/ACCP guidelines do not recommend screening patients who are asymptomatic and with clinical stage I NSCLC. However, brain metastasis sometimes occurs in early stage NSCLC patients without any neurological symptoms. METHODS: We retrospectively reviewed medical records of 124 patients admitted to the University of Tokyo Hospital with stage IV NSCLC from January 2012 to April 2016...
February 26, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29399516/below-knee-deep-vein-thrombosis-dvt-diagnostic-and-treatment-patterns
#6
Drew Fleck, Hassan Albadawi, Alex Wallace, Grace Knuttinen, Sailendra Naidu, Rahmi Oklu
Background: Guidelines are lacking for isolated below-knee deep vein thrombosis (BKDVT). The American College of Chest Physicians (ACCP) suggests anticoagulation only if symptoms are severe, otherwise surveillance with follow-up ultrasound in 2 weeks is recommended. Yet clinical practice remains highly variable. Little is known about the natural history of BKDVT and how to best manage these patients. Methods: A retrospective analysis was conducted of medical records from 2014-2016...
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29375058/resolving-family-clinician-disputes-in-the-context-of-contested-definitions-of-futility
#7
Gabriel T Bosslet, Bernard Lo, Douglas B White
The word futile has been a touchstone in debates regarding resolution of disputes regarding life-prolonging treatments since the 1980s. Here, we respond to several criticisms of the Multiorganization Policy Statement, "An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units" (Bosslet et al. 2015). This response highlights the need for a strict definition of the word futile in order to avoid undue treatment differences when end-of-life interventions are contested...
2018: Perspectives in Biology and Medicine
https://www.readbyqxmd.com/read/29319159/leveraging-big-data-in-pediatric-development-programs-proceedings-from-the-2016-american-college-of-clinical-pharmacology-annual-meeting-symposium
#8
REVIEW
Lily Yeruk Mulugeta, Lynne Yao, Diane Mould, Brian Jacobs, Jeffrey Florian, Brian Smith, Vikram Sinha, Jeffrey S Barrett
This article discusses the use of big data in pediatric drug development. The article covers key topics discussed at the ACCP annual meeting symposium in 2016 including the extent to which big data or real-world data can inform clinical trial design and substitute for efficacy and safety data typically obtained in clinical trials. The current states of use, opportunities, and challenges with the use of big data in future pediatric drug development are discussed.
January 10, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29110872/venous-thromboembolism-risks-and-prophylaxis-in-king-fahad-hospital-madinah-saudi-arabia
#9
Ayman Kharaba, Mohammad Al Aboud, Madinah Reham Kharabah, Khaled Alyami, Amal Al Beihany
OBJECTIVE: To evaluate the risk factors, physician's compliance, and implementation of the American College of Chest Physicians (ACCP) guidelines for venous thromboembolism (VTE) prophylaxis at our hospital. METHODS: A retrospective cohort study was conducted in King Fahad Hospital, Madinah, Saudi Arabia, from July 2015 to September 2015. We used the ACCP 2012 guidelines to assess the VTE risk and to determine whether patients had received the recommended prophylaxis...
December 2017: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/29106816/insulin-glargine-300-u-ml-is-associated-with-less-weight-gain-while-maintaining-glycemic-control-and-low-risk-of-hypoglycemia-compared-with-insulin-glargine-100-u-ml-in-an-aging-population-with-type-2-diabetes
#10
Medha N Munshi, Jasvinder Gill, Jason Chao, Elena V Nikonova, Meenakshi Patel
OBJECTIVE: Assess efficacy, hypoglycemia, and weight gain in patients with type 2 diabetes (T2D) treated with insulin glargine 300 U/mL (Gla-300) or 100 U/mL (Gla-100) across different age groups. METHODS: Pooled data were generated for patients randomized to Gla-300 or Gla-100 in the EDITION 2 (NCT01499095) and 3 (NCT01676220) studies. In 4 age groups (<55, ≥55 to <60, ≥60 to <65, ≥65 years), glycated hemoglobin A1C (A1C), percentage of patients reaching A1C <7...
February 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29094871/reflux-cough-syndrome-guidelines-from-the-accp
#11
Marselle Bredemeyer
No abstract text is available yet for this article.
November 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28902808/-anticoagulant-therapy-of-venous-thromboembolic-complications-balancing-between-risks
#12
REVIEW
K V Lobastov, S V Sapelkin
This article is a review of the literature, related to the problem of recurrence of venous thromboembolic complications and the possibilities of their secondary prevention. The problems of determining the rational duration of anticoagulant therapy on the basis of an individual assessment of its benefit and risk are considered. The information on modern prognostic models allowing quantitative assessment of the probability of hemorrhagic and thrombotic events occurrence is presented (Vienna prediction model, DASH, HAS-BLED, stratification according to ACCP 2016)...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28889105/inducible-laryngeal-obstruction-an-official-joint-european-respiratory-society-and-european-laryngological-society-statement
#13
Thomas Halvorsen, Emil Schwarz Walsted, Caterina Bucca, Andrew Bush, Giovanna Cantarella, Gerhard Friedrich, Felix J F Herth, James H Hull, Harald Jung, Robert Maat, Leif Nordang, Marc Remacle, Niels Rasmussen, Janet A Wilson, John-Helge Heimdal
Inducible laryngeal obstruction (ILO) describes an inappropriate, transient, reversible narrowing of the larynx in response to external triggers. ILO is an important cause of a variety of respiratory symptoms and can mimic asthma. Current understanding of ILO has been hampered by imprecise nomenclature and variable approaches to assessment and management. A task force of the European Respiratory Society (ERS) and European Laryngological Society (ELS) was thus set up to address this, and to identify research priorities...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28802287/energy-expenditure-in-severe-sepsis-or-septic-shock-in-a-thai-medical-intensive-care-unit
#14
Anupol Panitchote, Nontapak Thiangpak, Pranithi Hongsprabhas, Cameron Hurst
BACKGROUND AND OBJECTIVES: Energy expenditure in severe sepsis/septic shock patients was measured by indirect calorimetry and the correlation of energy expenditure between indirect calorimetry and predictive equations was determined. METHODS AND STUDY DESIGN: This was a prospective, observational analytical study. Severe sepsis or septic shock patients were measured for energy expenditure over 72 hours by indirect calorimetry that was measured by a mechanical ventilator (EngströmCarestation, GE Healthcare)...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28800668/-epidemiology-risk-factors-and-risk-stratification-of-venous-thromboembolism-in-pregnancy-and-the-puerperium
#15
Panagiotis Tsikouras, Georg-Friedrich von Tempelhoff, Werner Rath
Venous thromboembolism (VTE) remains a leading cause of direct maternal deaths in the developed countries. The incidence of VTE has increased significantly during the past two decades. The absolute risk of VTE is estimated 0.6-2.2 per 1000 deliveries. Compared with age-matched non-pregnant women, the daily risk of VTE is increased 7- to 10-fold for antepartum VTE, but it is 15- to 35-fold for postpartum VTE. The incidence of pulmonary embolism (PE) during the first 6 weeks postpartum is nearly 15-fold higher compared to the incidence in pregnancy, and remains significantly increased up to 12 weeks postpartum...
August 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28738966/-lung-nodules-assessment-analysis-of-four-guidelines
#16
Chunquan Liu, Yong Cui
In the past 20 years, with the popularization of low-dose computed tomography (CT) screening, detection rate of lung nodules increased significantly. However, there are still many difficulties in making qualitative diagnosis for pulmonary nodules. The Lung nodule is a clinical common lung disease. The early onset for malignant nodules is quite hidden. Without early intervention, the course of disease can develop rapidly. For malignant nodules, the exacerbation can be very severe. Besides, the therapeutic effect can be unsatisfactory...
July 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28645546/post-sepsis-cognitive-impairment-and-associated-risk-factors-a-systematic-review
#17
REVIEW
Allan J C Calsavara, Vandack Nobre, Tatiana Barichello, Antonio L Teixeira
INTRODUCTION: Post-sepsis cognitive impairment is one of the major sequelae observed in survivors of sepsis. This cognitive impairment can be global or may affect specific domains. A better understanding of these deficits and associated risk factors could influence the care of patients with sepsis. OBJECTIVE: To perform a systematic review to investigate the presence of cognitive impairment and its associated risk factors among patients who survived sepsis. METHODS: The search was conducted in MEDLINE (1966 to March 2017) and EMBASE (1988 to March 2017)...
June 20, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/28640324/new-paradigms-in-venous-thromboprophylaxis-of-medically-ill-patients
#18
Alex C Spyropoulos, Gary E Raskob
Acutelly-ill hospitalised medical patients are at risk of venous thromboembolism (VTE), both in-hospital and in the immediate post-discharge period, and mortality from VTE is thought to be particularly high in this patient population. However, despite previous mandates from international antithrombotic guidelines such as those of the American College of Chest Physicians (ACCP) for the "universal" use of thromboprophylaxis in hospitalised medical patients, global audits suggest that implementation of thromboprophylaxis continues to be challenging because of the perceived higher risk of bleeding and lower risk of VTE than that reported in clinical trials...
August 30, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28639605/-the-definition-of-sepsis-25-year-experience-of-concept-development
#19
V P Sazhin, A M Karsanov, S S Maskin, O V Remizov
The review, presented in chronological order the stages of formation of the modern definition of sepsis syndrome, since the recommendations of the conciliation conference ACCP/SCCM (1991), the experience of the practical use of which has been extensively critically assessed in future studies. As a result, it formed a strong opinion that the global challenge of early diagnosis of sepsis, under the previously proposed definitive categories have not been solved, moreover, in the scientific community formed a firm belief in the need to make fundamental changes in the definition of the term 'sepsis'...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28600867/reply-to-the-hematology-oncology-pharmacy-association-alternative-viewpoint-on-the-2016-accp-pharmacotherapy-didactic-curriculum-toolkit
#20
Terry L Schwinghammer, Drayton A Hammond, Andrew J Crannage
No abstract text is available yet for this article.
August 2017: Pharmacotherapy
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