M J Rodríguez Salazar, J M Raya Sánchez, R Rodríguez Sánchez, M M Alonso Socas, M L Brito Barroso, L Hernández Nieto
Primary effusion lymphoma (PEL) is a recently individualized form of non-Hodgkin lymphoma (WHO classification) that mainly develops in HIV infected males, more frequently in homosexuals and advanced stages of the disease (total CD4+ lymphocyte count below 100-200/mL). Occasionally, it appears in others immunodepressive states (such as solid organs postransplant period) and even, although very rarelly, in immunocompetents patients. From a pathogenetic point of view, PEL has been related to Kaposi's sarcoma-associated herpes virus (also named human herpesvirus 8) and to the clinical antecedent of Kaposís sarcoma...
April 2004: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna