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journal of sex medicine

Sharad Hernot, Raman Wadhera, Madhuri Kaintura, Sandeep Bhukar, Dheeraj Shashikumar Pillai, Usha Sehrawat, Jitu Sam George
INTRODUCTION: Tracheocutaneous fistula (TCF) is one of the recognized sequelae of a long-term tracheostomy resulting from mucocutaneous overgrowth which prevents closure of the artificial lumen at the site of tracheostomy. Primary closure of TCF has disappointing results and may lead to complications like pneumothorax, pneumomediastinum, cervicofacial subcutaneous emphysema, and depressed scar. OBJECTIVE: To compare TCF repair using fistulectomy followed by rhomboid flap versus fistulectomy followed by Z plasty repair...
October 4, 2016: Aesthetic Plastic Surgery
Gabriela B Gomez, Robyn Eakle, Judie Mbogua, Godspower Akpomiemie, W D Francois Venter, Helen Rees
INTRODUCTION: Updated guidelines from the WHO recommend antiretroviral treatment for adults with HIV at any CD4 count and daily oral pre-exposure prophylaxis (PrEP) for people at substantial risk of HIV infection. However, implementation challenges may hinder the ability of programmes to translate these recommendations into successful practice. This demonstration project is the first to integrate PrEP and immediate treatment (ITx) for female sex workers (FSWs) in South Africa to answer operational research questions...
2016: BMJ Open
Metin Temel
BACKGROUND: This study aimed to present the long-term results of the consolidative technique otoplasty (CTO). METHODS: Patient age, sex, duration of follow-up, and how the deformity (bilateral-unilateral) occurred were determined. The kind of anesthesia, duration of surgery, surgical techniques used during the operation were reported, and the preoperative and postoperative distances between the ear and head were measured at four points (SUP: The highest point of the helix; SCA: the concha superior sticking points; ICA: stick point of Concha at the inferior; and lobular)...
September 9, 2016: Aesthetic Plastic Surgery
D Agnoletti, A S Mansour, Y Zhang, A D Protogerou, S Ouerdane, J Blacher, M E Safar
Diabetes complications increase with disease duration. No study was performed on the relationship between aortic stiffness and diabetes duration, taking into account the respective influence of such factors on macro- and microcirculation. In total, 618 subjects with type 2 diabetes (259 men) attending the Department of Internal Medicine of Tizi Ouzou Hospital (Algeria) were studied in collaboration with Hotel-Dieu Hospital (Paris, France). Brachial blood pressure (BP), anthropometric, clinical and biological data were evaluated...
September 8, 2016: Journal of Human Hypertension
Neel A Mansukhani, Dustin Y Yoon, Katherine A Teter, Vanessa C Stubbs, Irene B Helenowski, Teresa K Woodruff, Melina R Kibbe
Importance: Sex is a variable that is poorly controlled for in clinical research. Objectives: To determine if sex bias exists in human surgical clinical research, to determine if data are reported and analyzed using sex as an independent variable, and to identify specialties in which the greatest and least sex biases exist. Design, Setting, and Participants: For this bibliometric analysis, data were abstracted from 1303 original peer-reviewed articles published from January 1, 2011, through December 31, 2012, in 5 surgery journals...
August 17, 2016: JAMA Surgery
L Aagaard, C E Hallgreen, E H Hansen
BACKGROUND: Use of anti-obesity medicines has been linked with serious cardiac and psychiatric adverse events (AEs). Spontaneous reports can provide information about serious, rare and unknown AEs occurring after time of marketing. In Europe, information about AEs reported for anti-obesity medicines can be accessed in the EudraVigilance database (EV). Therefore, we aimed to identify and characterise adverse events (AEs) associated with use of anti-obesity medicines in Europe. METHODS: AE reports submitted for anti-obesity medicines (Anatomical Therapeutic Chemical [ATC] group A08A) from 2007 to 2014 and located in EV were analysed...
August 1, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Paola De Castro, Shirin Heidari, Thomas F Babor
Sex and gender are important determinants of health and influence research findings in a variety of ways, yet they are often overlooked and underreported. This oversight limits the generalizability of research findings and their applicability to clinical practice. The objective of this paper is to point out how journal editors can influence better reporting of sex and gender in research by establishing a methodological framework directly addressing authors of scientific publications, as well as referees, and indirectly affecting all the stakeholders in the research cycle, from funders to policy-makers and citizens...
April 2016: Annali Dell'Istituto Superiore di Sanità
Ulrich Dirnagl
Based on research, mainly in rodents, tremendous progress has been made in our basic understanding of the pathophysiology of stroke. After many failures, however, few scientists today deny that bench-to-bedside translation in stroke has a disappointing track record. I here summarize many measures to improve the predictiveness of preclinical stroke research, some of which are currently in various stages of implementation: We must reduce preventable (detrimental) attrition. Key measures for this revolve around improving preclinical study design...
August 2016: Stroke; a Journal of Cerebral Circulation
Matthew Quaife, Robyn Eakle, Maria Cabrera, Peter Vickerman, Motlalepule Tsepe, Fiona Cianci, Sinead Delany-Moretlwe, Fern Terris-Prestholt
INTRODUCTION: For the past few decades, condoms have been the main method of HIV prevention. Recent advances in antiretroviral (ARV)-based prevention products have substantially changed the prevention landscape, yet little is known about how popular these products will be among potential users, or whether new methods might be used in conjunction with, or instead of, condoms. This study will use a discrete choice experiment (DCE) to (1) explore potential users' preferences regarding HIV prevention products, (2) quantify the importance of product attributes and (3) predict the uptake of products to inform estimates of their potential impact on the HIV epidemic in South Africa...
2016: BMJ Open
Matthew M Churpek, Blair Wendlandt, Frank J Zadravecz, Richa Adhikari, Christopher Winslow, Dana P Edelson
BACKGROUND: Previous research investigating the impact of delayed intensive care unit (ICU) transfer on outcomes has utilized subjective criteria for defining critical illness. OBJECTIVE: To investigate the impact of delayed ICU transfer using the electronic Cardiac Arrest Risk Triage (eCART) score, a previously published early warning score, as an objective marker of critical illness. DESIGN: Observational cohort study. SETTING: Medical-surgical wards at 5 hospitals between November 2008 and January 2013...
June 28, 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Sara Belga, Sumit R Majumdar, Sharry Kahlon, Jenelle Pederson, Darren Lau, Raj S Padwal, Mary Forhan, Jeffrey A Bakal, Finlay A McAlister
BACKGROUND: Multiple tools are used to identify frailty. OBJECTIVE: To compare the global Clinical Frailty Scale (CFS) with more objective phenotypic tools (modified Fried score and the Timed Up and Go Test [TUGT]). DESIGN: Prospective cohort study. SETTING: General medical wards in Edmonton, Canada. PARTICIPANTS: Adults being discharged back to the community. MEASUREMENTS: All frailty assessments were done within 24 hours of discharge...
August 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Susan P Phillips, Katarina Hamberg
BACKGROUND: Although observational data show social characteristics such as gender or socio-economic status to be strong predictors of health, their impact is seldom investigated in randomised controlled studies (RCTs). OBJECTIVE & DESIGN: Using a random sample of recent RCTs from high-impact journals, we examined how the most often recorded social characteristic, sex/gender, is considered in design, analysis, and interpretation. Of 712 RCTs published from September 2008 to 31 December 2013 in the Annals of Internal Medicine, British Medical Journal, Lancet, Canadian Medical Association Journal, or New England Journal of Medicine, we randomly selected 57 to analyse funding, methods, number of centres, documentation of social circumstances, inclusion/exclusion criteria, proportions of women/men, and reporting about sex/gender in analyses and discussion...
2016: Global Health Action
Shahryar Cohanzad
OBJECTIVE: To introduce the operative technique of "extensive metoidioplasty" (EM) in female transsexual surgery, for achieving an effective reconstruction of a male-appearing, normally functioning, fully sensate and erectile external genitalia. PATIENTS AND METHODS: Ten female transsexuals (46 xx karyotype) between the ages of 20 and 40 years underwent EM as their sex reassignment surgical procedure with the mean operative time of 171 min (45-211, SD 19.55 min) between 2007 and 2014 in a general hospital in Tehran, Iran...
February 2016: Aesthetic Plastic Surgery
R Holleyman, S Vann Jones
BACKGROUND: Stress and mortality are negatively correlated and it is generally accepted that certain professions are more stressful than others. Medical graduates begin as a relatively homogenous population who then choose vastly different career options making doctors an ideal population in which to try to assess whether job stress is likely to be causal to increased mortality. AIMS: To establish the influence of various modifiable risk factors on the life expectancy of UK doctors...
June 2016: Occupational Medicine
Vladimir Neychev, Vanyo Mitev
ETHNO-PHARMACOLOGICAL RELEVANCE: Historically, aphrodisiacs have had a reputation for making sex more achievable and satisfying. It has been long believed that Tribulus terrestris L. (TT), an annual plant of the family Zygophyllaceae, possesses aphrodisiac properties purportedly attributed to its ability to influence levels or mimic function of sex hormones. Due to this appealing beliefs, the popularity of medicinal products from TT is expanding at a remarkable pace among consumers who are attempting to enhance their sexual health...
February 17, 2016: Journal of Ethnopharmacology
David Silvestri, Sukhjit S Takhar
No abstract text is available yet for this article.
January 2016: Annals of Emergency Medicine
Stefan Danilla, Pedro Cuevas, Sócrates Aedo, Carlos Dominguez, Rocío Jara, María E Calderón, Sarah Al-Himdani, Marco A Rios, Cristián Taladriz, Diego Rodriguez, Rolando Gonzalez, Ángel Lazo, Cristián Erazo, Susana Benitez, Patricio Andrades, Sergio Sepúlveda
OBJECTIVE: To develop a new patient-reported outcome instrument (PRO) to measure body-related satisfaction quality of life (QoL). METHODS: Standard 3-phase PRO design was followed; in the first phase, a qualitative design was used in 45 patients to develop a conceptual framework and to create preliminary scale domains and items. In phase 2, large-scale population testing on 1340 subjects was performed to reduce items and domains. In phase 3, final testing of the developed instrument on 34 patients was performed...
February 2016: Aesthetic Plastic Surgery
Franck Marie Leclère, Vincent Casoli, Jacques Baudet, Romain Weigert
INTRODUCTION: Male-to-female sex reassignment surgery involves three main procedures, namely, clitoroplasty, new urethral meatoplasty and vaginopoiesis. Herein we describe the key steps of our surgical technique. METHODS: Male-to-female sex reassignment surgery includes the following 14 key steps which are documented in this article: (1) patient installation and draping, (2) urethral catheter placement, (3) scrotal incision and vaginal cavity formation, (4) bilateral orchidectomy, (5) penile skin inversion, (6) dismembering of the urethra from the corpora, (7) neoclitoris formation, (8) neoclitoris refinement, (9) neovaginalphallic cylinder formation, (10) fixation of the neoclitoris, (11) neovaginalphallic cylinder insertion, (12) contouring of the labia majora and positioning the neoclitoris and urethra, (13) tie-over dressing and (14) compression dressing...
December 2015: Aesthetic Plastic Surgery
Carolyn M Hettrich, Sommer Hammoud, Lauren E LaMont, Elizabeth A Arendt, Jo A Hannafin
BACKGROUND: In 2001, the Institute of Medicine released a report stating that sex must be considered in all aspects and at all levels of biomedical research. Knowledge of differences between males and females in responses to treatment serves to improve our ability to care for our patients. QUESTIONS/PURPOSES: The purpose of our study was to determine (1) if there is an increase in the proportion of sex-specific reporting from 2000 to 2005 and to 2010; and (2) whether there is a proportional difference in such reporting based on journal type: subspecialty versus general orthopaedics...
December 2015: Clinical Orthopaedics and related Research
Ingela Hasselqvist-Ax, Gabriel Riva, Johan Herlitz, Mårten Rosenqvist, Jacob Hollenberg, Per Nordberg, Mattias Ringh, Martin Jonsson, Christer Axelsson, Jonny Lindqvist, Thomas Karlsson, Leif Svensson
BACKGROUND: Three million people in Sweden are trained in cardiopulmonary resuscitation (CPR). Whether this training increases the frequency of bystander CPR or the survival rate among persons who have out-of-hospital cardiac arrests has been questioned. METHODS: We analyzed a total of 30,381 out-of-hospital cardiac arrests witnessed in Sweden from January 1, 1990, through December 31, 2011, to determine whether CPR was performed before the arrival of emergency medical services (EMS) and whether early CPR was correlated with survival...
June 11, 2015: New England Journal of Medicine
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