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Premature ventricular complexes

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https://www.readbyqxmd.com/read/28431063/left-ventricular-dysfunction-is-associated-with-frequent-premature-ventricular-complexes-and-asymptomatic-ventricular-tachycardia-in-children
#1
R A Bertels, L M Harteveld, L H Filippini, S A Clur, N A Blom
Aims: To assess the risk factors for left ventricular (LV) dysfunction in a paediatric population with idiopathic frequent premature ventricular contractions (PVCs) and asymptomatic ventricular tachycardias (VTs). Methods and Results: Paediatric patients with the diagnosis of idiopathic frequent PVCs and asymptomatic VTs were retrospectively evaluated. Frequent PVCs were defined as ≥5% on 24 h Holter recording. Left ventricular dysfunction was defined as a shortening fraction of ≤28%...
April 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28424631/mechanisms-underlying-the-emergence-of-post-acidosis-arrhythmia-at-the-tissue-level-a-theoretical-study
#2
Jieyun Bai, Renli Yin, Kuanquan Wang, Henggui Zhang
Acidosis has complex electrophysiological effects, which are associated with a high recurrence of ventricular arrhythmias. Through multi-scale cardiac computer modeling, this study investigated the mechanisms underlying the emergence of post-acidosis arrhythmia at the tissue level. In simulations, ten Tusscher-Panfilov ventricular model was modified to incorporate various data on acidosis-induced alterations of cellular electrophysiology and intercellular electrical coupling. The single cell models were incorporated into multicellular one-dimensional (1D) fiber and 2D sheet tissue models...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28414603/cardiovascular-findings-in-ponies-with-equine-metabolic-syndrome
#3
Natalie Heliczer, Vinzenz Gerber, Rupert Bruckmaier, Johannes H van der Kolk, Cristobal Navas de Solis
OBJECTIVE To determine whether hypertension, high sympathetic tone, resting and exercising arrhythmias, and echocardiographic changes consistent with hypertensive cardiomyopathy were associated with equine metabolic syndrome (EMS) in ponies. DESIGN Prospective case-control study. ANIMALS 19 privately owned ponies with a diagnosis of EMS (history of laminitis, body condition score ≥ 7/9, cresty neck score ≥ 3/5, and abnormal oral sugar test result; cases) and 20 healthy control ponies. PROCEDURES Heart rate (HR), noninvasively measured arterial blood pressure (BP), markers of autonomic tone (splenic volume and HR variability), 24-hour and exercising ECGs, and echocardiograms were compared between cases and controls...
May 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28403080/characteristics-of-diurnal-ventricular-premature-complex-variation-in-right-ventricular-outflow-tract-arrhythmias-after-catheter-ablation
#4
Shih-Jie Jhuo, Li-Wei Lo, Shih-Lin Chang, Yenn-Jiang Lin, Fa-Po Chung, Yu-Feng Hu, Tze-Fan Chao, Ta-Chuan Tuan, Jo-Nan Liao, Chin-Yu Lin, Yao-Ting Chang, Chung-Hsing Lin, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Sunu Budhi Raharjo, Wei-Hua Tang, Kun-Tai Lee, Wen-Ter Lai, Shih-Ann Chen
Diurnal variations in ventricular tachyarrhythmias (VAs) have been demonstrated in idiopathic arrhythmogenic heart disease. The electrophysiological characteristics of diurnal variations in idiopathic right ventricular outflow tract (RVOT) VA have not previously been elucidated. Sixty-two consecutive patients undergoing catheter ablation for idiopathic RVOT VA (mean age: 42.8 ± 12.3 years, 35 females) were enrolled. The diurnal variation type (group 1, n = 36) was defined as those patients who had most ventricular premature contractions (VPCs) during the night hours by preprocedure Holter recordings...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28388306/premature-ventricular-complex-is-more-prevalent-during-acute-exacerbated-than-stable-states-of-chronic-obstructive-pulmonary-disease-and-is-related-to-cardiac-troponin-t
#5
Gunnar Einvik, Rahul Bhatnagar, Nils Henrik Holmedahl, Anke Neukamm, Torbjørn Omland, Vidar Søyseth
During acute exacerbation of chronic obstructive pulmonary disease (AECOPD), myocardial stress may be aggravated. Sparse data exist concerning the prevalence and correlates of cardiac arrhythmias in the stable and exacerbated states of COPD. We hypothesized that AECOPD is associated with increased prevalence of cardiac arrhythmias independent of COPD-severity and co-morbidity, and explored possible mechanisms. A 24-hour Holter recording was obtained in 74 patients with stable COPD and 45 patients with AECOPD (mean age 54 years, 56% women)...
April 7, 2017: COPD
https://www.readbyqxmd.com/read/28367337/premature-ventricular-complex-causing-ice-pick-headache
#6
Selcuk Ozturk, Ertan Yetkin
Ice pick headache is a momentary, transient, repetitive headache disorder and manifests with the stabbing pains and jolts. The exact mechanism causing this disease is unknown. Premature ventricular contractions are early depolarization of the ventricular myocardium and in the absence of a structural heart disease, it is considered to be a benign disease. In this report, we describe a male patient presenting with the symptom of momentary headache attacks accompanied with instant chest pain which is associated with premature ventricular contraction...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28339558/impact-of-sedation-vs-general-anaesthesia-on-percutaneous-epicardial-access-safety-and-procedural-outcomes
#7
Ammar M Killu, Alan Sugrue, Thomas M Munger, David O Hodge, Siva K Mulpuru, Christopher J McLeod, Douglas L Packer, Samuel J Asirvatham, Paul A Friedman
Aims: Patient movement while under moderate/deep sedation may complicate percutaneous epicardial access (EpiAcc), mapping and ablation. We sought to compare procedural outcomes in patients undergoing EpiAcc under sedation vs. general anaesthesia (GA) for ablation. Methods and results: Patients undergoing EpiAcc between January 2004 and July 2014 were included. Safety, procedural, and clinical outcomes were compared between patients undergoing EpiAcc under sedation or GA for ventricular tachycardia or premature ventricular complex ablation...
November 15, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28326823/tp-e-interval-and-tp-e-qt-ratio-before-and-after-catheter-ablation-in-patients-with-premature-ventricular-complexes
#8
Çağrı Yayla, Fırat Özcan, Dursun Aras, Osman Turak, Özcan Özeke, Serkan Çay, Serkan Topaloğlu
AIM: Tp-e/QT ratio is a novel marker of ventricular repolarization. The aim of the study is to evaluate the Tp-e interval and Tp-e/QT ratio before and after radiofrequency ablation (RFA) for patients with frequent premature ventricular complexes (PVCs). PATIENTS & METHODS: The study included 151 consecutive patients who underwent RFA for treatment of symptomatic frequent PVCs. RESULTS: Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio (all p < 0...
April 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28324925/non-invasive-imaging-of-ventricular-activation-during-pacing-and-arrhythmia-methods-and-validation
#9
Long Yu, Steven Pogwizd, Bin He
Cardiovascular disease continued to be a leading killer world widely. Each year, about 400,000 cases of sudden cardiac arrest are reported in the U.S. alone. Clinically, radio-frequency ablative procedure has become widely applied in the treatment of ventricular arrhythmia. Non-invasive approaches have been demonstrated to be able to provide important information on the arrhythmogenesis and potentially assist in the clinical practice. In this work, we develop and validate a novel temporal sparse based imaging method, Cardiac Electrical Sparse Imaging (CESI)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28285456/is-vf-an-ablatable-rhythm
#10
REVIEW
Ghassen Cheniti, Meleze Hocini, Ruairidh Martin, Frederic Sacher, Remi Dubois, Michel Haissaguerre, Pierre Jais
Ventricular fibrillation (VF) has traditionally been considered to be a disorganized arrhythmia not amenable to catheter ablation. However, a better understanding of the VF pathophysiology has allowed identification of targets for ablation. Ablation targeting the premature ventricular complexes which trigger VF was proven to be associated with high success rates and long-term freedom from VF recurrence. Recent mapping data has identified rotors, focal breakthroughs, and figure of eight re-entries as main drivers maintaining human VF...
February 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28283315/a-congenital-left-ventricular-aneurysm-a%C3%A2-cause-of-premature-ventricular-complex-in-a-premature-infant
#11
Wei-Li Hung, Shyh-Jye Chen, Shan-Miao Lin, Ming-Ren Chen
No abstract text is available yet for this article.
April 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28280349/prognostic-indices-among-hypertensive-heart-failure-patients-in-nigeria-the-roles-of-24-hour-holter-electrocardiography-and-6-minute-walk-test
#12
Tuoyo O Mene-Afejuku, Michael O Balogun, Anthony O Akintomide, Rasaaq A Adebayo
BACKGROUND: Hypertensive heart failure (HHF) is associated with a poor prognosis. There is paucity of data in Nigeria on prognosis among HHF patients elucidating the role of 24-hour Holter electrocardiogram (ECG) in concert with other risk factors. OBJECTIVE: The aim of this study was to determine the prognostic utility of 24-hour Holter ECG, the 6-minute walk test (6-MWT), echocardiography, clinical and laboratory parameters among HHF patients. METHODS: A total of 113 HHF patients were recruited and followed up for 6 months...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28255076/beneficial-effect-of-renal-denervation-on-ventricular-premature-complex-induced-cardiomyopathy
#13
Shinya Yamada, Li-Wei Lo, Yu-Hui Chou, Wei-Lun Lin, Shih-Lin Chang, Yenn-Jiang Lin, Shin-Huei Liu, Wen-Han Cheng, Tsung-Ying Tsai, Shih-Ann Chen
BACKGROUND: Frequent ventricular premature complexes (VPCs) can lead to the development of dilated cardiomyopathy and sudden cardiac death. Renal artery sympathetic denervation (RDN) may protect the heart from remodeling. This study aimed to investigate the effect of frequent VPCs on structural and electrical properties and whether RDN can protect the heart from remodeling. METHODS AND RESULTS: Eighteen rabbits were randomized to control (n=6), VPC (n=6), and VPC-RDN (n=6) groups...
March 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28252842/effects-of-transendocardial-stem-cell-injection-on-ventricular-proarrhythmia-in-patients-with-ischemic-cardiomyopathy-results-from-the-poseidon-and-tac-hft-trials
#14
Archana Ramireddy, Chad R Brodt, Adam M Mendizabal, Darcy L DiFede, Chris Healy, Vishal Goyal, Yahya Alansari, James O Coffey, Juan F Viles-Gonzalez, Alan W Heldman, Jeffrey J Goldberger, Robert J Myerburg, Joshua M Hare, Raul D Mitrani
Transendocardial stem cell injection in patients with ischemic cardiomyopathy (ICM) improves left ventricular function and structure but has ill-defined effects on ventricular arrhythmias. We hypothesized that mesenchymal stem cell (MSC) implantation is not proarrhythmic. Post hoc analyses were performed on ambulatory ECGs collected from the POSEIDON and TAC-HFT trials. Eighty-eight subjects (mean age 61 ± 10 years) with ICM (mean EF 32.2% ± 9.8%) received treatment with MSC (n = 48), Placebo (n = 21), or bone marrow mononuclear cells (BMC) (n = 19)...
March 2, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28226451/non-invasive-imaging-of-ventricular-activation-during-pacing-and-arrhythmia-methods-and-validation
#15
Long Yu, Steven Pogwizd, Bin He, Long Yu, Steven Pogwizd, Bin He, Bin He, Steven Pogwizd, Long Yu
Cardiovascular disease continued to be a leading killer world widely. Each year, about 400,000 cases of sudden cardiac arrest are reported in the U.S. alone. Clinically, radio-frequency ablative procedure has become widely applied in the treatment of ventricular arrhythmia. Non-invasive approaches have been demonstrated to be able to provide important information on the arrhythmogenesis and potentially assist in the clinical practice. In this work, we develop and validate a novel temporal sparse based imaging method, Cardiac Electrical Sparse Imaging (CESI)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28214002/relation-between-ventricular-premature-complexes-and-incident-heart-failure
#16
Vratika Agarwal, Eric Vittinghoff, Isaac R Whitman, Thomas A Dewland, Jonathan W Dukes, Gregory M Marcus
Ventricular premature complexes (VPCs) may represent a reversible cause of heart failure (HF); however, the type of patients most prone remains unknown. This study leverages a large population-based database to examine interactions that might prove clinically useful in risk-stratifying patients with VPCs. We used the California Healthcare Cost and Utilization Project to identify patients with VPCs and incident systolic HF from January 1, 2005, to December 31, 2009. We calculated hazard ratios for predictors of incident systolic HF using multivariable Cox proportional hazard models...
April 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28183845/incidence-of-idiopathic-ventricular-arrhythmias-a-population-based-study
#17
Surksha Sirichand, Ammar M Killu, Deepak Padmanabhan, David O Hodge, Alanna M Chamberlain, Peter A Brady, Suraj Kapa, Peter A Noseworthy, Douglas L Packer, Thomas M Munger, Bernard J Gersh, Christopher J McLeod, Win-Kuang Shen, Yong-Mei Cha, Samuel J Asirvatham, Paul A Friedman, Siva K Mulpuru
BACKGROUND: Ventricular tachycardia and premature ventricular complexes (PVCs) most frequently occur in the context of structural heart disease. However, the burden of idiopathic ventricular arrhythmias (IVA) in the general population is unknown. METHODS AND RESULTS: We identified incident cases of IVA between 2005 and 2013 from Olmsted County, Minnesota, using the Rochester Epidemiology Project database. For PVC cohorts, we included those with frequent (defined as ≥100 PVC/24 hours) symptomatic PVCs...
February 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28167081/premature-ventricular-complex-ablation-in-structural-heart-disease
#18
REVIEW
Rakesh Latchamsetty, Frank Bogun
Frequent premature ventricular complexes (PVCs) in patients with underlying structural heart disease, particular after myocardial infarction, can predict increased mortality. Use of antiarrhythmic medications to suppress PVCs in this setting can result in a further increase in mortality. High PVC burdens in patients with structural heart disease can cause or worsen cardiomyopathy and successful elimination of PVCs with catheter ablation can improve or, in some cases normalize, cardiac function. PVCs may also trigger more malignant ventricular arrhythmias, particularly in patients with previous myocardial infarction, and when identified can be mapped and ablated...
March 2017: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/28137981/sudden-cardiac-death-the-pro-arrhythmic-interaction-of-an-acute-loading-with-an-underlying-substrate
#19
George R Sutherland
Sudden cardiac death (SCD) is a complex phenomenon, occurring either in apparently normal individuals or in those where there is a recognized underlying cardiac abnormality. In both groups, the lethal arrhythmia has frequently been related to the physiologic trigger of either exercise or stress. Prior research into SCD has focused mainly on a combination of identifying either vulnerable myocardial substrates; pharmacological approaches to altering electrical activation/repolarisation in substrates; or the suppression of induced lethal arrhythmias with implantable defibrillators...
January 29, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28128201/disruption-of-cardiac-cholinergic-neurons-enhances-susceptibility-to-ventricular-arrhythmias
#20
Christiane Jungen, Katharina Scherschel, Christian Eickholt, Pawel Kuklik, Niklas Klatt, Nadja Bork, Tim Salzbrunn, Fares Alken, Stephan Angendohr, Christiane Klene, Janos Mester, Nikolaj Klöcker, Marieke W Veldkamp, Udo Schumacher, Stephan Willems, Viacheslav O Nikolaev, Christian Meyer
The parasympathetic nervous system plays an important role in the pathophysiology of atrial fibrillation. Catheter ablation, a minimally invasive procedure deactivating abnormal firing cardiac tissue, is increasingly becoming the therapy of choice for atrial fibrillation. This is inevitably associated with the obliteration of cardiac cholinergic neurons. However, the impact on ventricular electrophysiology is unclear. Here we show that cardiac cholinergic neurons modulate ventricular electrophysiology. Mechanical disruption or pharmacological blockade of parasympathetic innervation shortens ventricular refractory periods, increases the incidence of ventricular arrhythmia and decreases ventricular cAMP levels in murine hearts...
January 27, 2017: Nature Communications
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